CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = Y87Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1287Y87YY4479YsyntaTtaC52735273113699-13701

Details of the mutation Y87Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1287Y87YtaTtaC52735273All0.001009
ORF1ab/nsp1287Y87YtaTtaC36163616AY.30.035966
ORF1ab/nsp1287Y87YtaTtaC804804AY.600.754221
ORF1ab/nsp1287Y87YtaTtaC149149AY.40.000232
ORF1ab/nsp1287Y87YtaTtaC143143AY.320.076145
ORF1ab/nsp1287Y87YtaTtaC107107AY.440.000651
ORF1ab/nsp1287Y87YtaTtaC8888B.1.617.20.000331
ORF1ab/nsp1287Y87YtaTtaC3333B.1.1.70.00003
ORF1ab/nsp1287Y87YtaTtaC2929B.1.10.000526
ORF1ab/nsp1287Y87YtaTtaC2222AY.250.000132
ORF1ab/nsp1287Y87YtaTtaC2020AY.430.000089
ORF1ab/nsp1287Y87YtaTtaC1818AY.1170.001521
ORF1ab/nsp1287Y87YtaTtaC1717AY.420.000684
ORF1ab/nsp1287Y87YtaTtaC1616AY.1020.000424
ORF1ab/nsp1287Y87YtaTtaC1616AY.46.60.001155
ORF1ab/nsp1287Y87YtaTtaC1515B.1.20.000132
ORF1ab/nsp1287Y87YtaTtaC1212AY.99.20.001106
ORF1ab/nsp1287Y87YtaTtaC1111AY.920.00316
ORF1ab/nsp1287Y87YtaTtaC77AY.470.000218
ORF1ab/nsp1287Y87YtaTtaC77P.1.140.000335
ORF1ab/nsp1287Y87YtaTtaC66AY.1030.000037
ORF1ab/nsp1287Y87YtaTtaC66AY.390.000148
ORF1ab/nsp1287Y87YtaTtaC66AY.460.000624
ORF1ab/nsp1287Y87YtaTtaC66AY.840.002625
ORF1ab/nsp1287Y87YtaTtaC66B.1.1.3750.071429
ORF1ab/nsp1287Y87YtaTtaC66B.1.177.210.000459
ORF1ab/nsp1287Y87YtaTtaC66B.1.6280.002114
ORF1ab/nsp1287Y87YtaTtaC55AY.230.000349
ORF1ab/nsp1287Y87YtaTtaC55AY.50.000103
ORF1ab/nsp1287Y87YtaTtaC55B.1.2430.000348
ORF1ab/nsp1287Y87YtaTtaC44AY.1000.000184
ORF1ab/nsp1287Y87YtaTtaC44AY.330.000267
ORF1ab/nsp1287Y87YtaTtaC44B.10.000037
ORF1ab/nsp1287Y87YtaTtaC33AY.1190.000106
ORF1ab/nsp1287Y87YtaTtaC33AY.39.10.000119
ORF1ab/nsp1287Y87YtaTtaC22AY.10.000791
ORF1ab/nsp1287Y87YtaTtaC22AY.1050.001286
ORF1ab/nsp1287Y87YtaTtaC22AY.1200.000074
ORF1ab/nsp1287Y87YtaTtaC22AY.200.000078
ORF1ab/nsp1287Y87YtaTtaC22AY.290.000032
ORF1ab/nsp1287Y87YtaTtaC22AY.4.20.000043
ORF1ab/nsp1287Y87YtaTtaC22AY.550.001835
ORF1ab/nsp1287Y87YtaTtaC22AY.670.000929
ORF1ab/nsp1287Y87YtaTtaC22AY.730.001331
ORF1ab/nsp1287Y87YtaTtaC22AY.740.000231
ORF1ab/nsp1287Y87YtaTtaC22AY.75.10.000361
ORF1ab/nsp1287Y87YtaTtaC22AY.880.001768
ORF1ab/nsp1287Y87YtaTtaC22AY.930.000546
ORF1ab/nsp1287Y87YtaTtaC22AY.950.001522
ORF1ab/nsp1287Y87YtaTtaC22B.1.1640.029851
ORF1ab/nsp1287Y87YtaTtaC22B.1.1770.000026
ORF1ab/nsp1287Y87YtaTtaC22B.1.5960.000174
ORF1ab/nsp1287Y87YtaTtaC11AY.1060.000335
ORF1ab/nsp1287Y87YtaTtaC11AY.1100.000113
ORF1ab/nsp1287Y87YtaTtaC11AY.1110.000183
ORF1ab/nsp1287Y87YtaTtaC11AY.1160.000287
ORF1ab/nsp1287Y87YtaTtaC11AY.130.000161
ORF1ab/nsp1287Y87YtaTtaC11AY.270.000065
ORF1ab/nsp1287Y87YtaTtaC11AY.340.000097
ORF1ab/nsp1287Y87YtaTtaC11AY.350.000233
ORF1ab/nsp1287Y87YtaTtaC11AY.370.000316
ORF1ab/nsp1287Y87YtaTtaC11AY.450.000122
ORF1ab/nsp1287Y87YtaTtaC11AY.46.10.001027
ORF1ab/nsp1287Y87YtaTtaC11AY.46.40.000165
ORF1ab/nsp1287Y87YtaTtaC11AY.5.30.000337
ORF1ab/nsp1287Y87YtaTtaC11AY.520.000814
ORF1ab/nsp1287Y87YtaTtaC11AY.580.000907
ORF1ab/nsp1287Y87YtaTtaC11AY.610.000105
ORF1ab/nsp1287Y87YtaTtaC11AY.70.000196
ORF1ab/nsp1287Y87YtaTtaC11AY.700.000209
ORF1ab/nsp1287Y87YtaTtaC11AY.750.000056
ORF1ab/nsp1287Y87YtaTtaC11AY.780.001541
ORF1ab/nsp1287Y87YtaTtaC11AY.98.10.000048
ORF1ab/nsp1287Y87YtaTtaC11B0.000128
ORF1ab/nsp1287Y87YtaTtaC11B.1.1.370.000193
ORF1ab/nsp1287Y87YtaTtaC11B.1.1.3720.000689
ORF1ab/nsp1287Y87YtaTtaC11B.1.1.5190.00004
ORF1ab/nsp1287Y87YtaTtaC11B.1.2100.002132
ORF1ab/nsp1287Y87YtaTtaC11B.1.2360.002053
ORF1ab/nsp1287Y87YtaTtaC11B.1.2400.000216
ORF1ab/nsp1287Y87YtaTtaC11B.1.360.000146
ORF1ab/nsp1287Y87YtaTtaC11B.1.466.20.000391
ORF1ab/nsp1287Y87YtaTtaC11B.1.5260.000024
ORF1ab/nsp1287Y87YtaTtaC11B.290.003509
ORF1ab/nsp1287Y87YtaTtaC11D.20.000075
ORF1ab/nsp1287Y87YtaTtaC11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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