CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V844L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12844V844LV5236LnonsynGtaTta1231190.9674815970-15972
ORF1ab/nsp12844V844LV5236LnonsynGtaCta12330.024390215970-15972
ORF1ab/nsp12844V844LV5236LnonsynGtACtG12310.0081300815970-15972

Details of the mutation V844L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12844V844LGtaTta119123All0.000023
ORF1ab/nsp12844V844LGtaCta3123All0.000001
ORF1ab/nsp12844V844LGtACtG1123All0
ORF1ab/nsp12844V844LGtaTta1313AY.260.000368
ORF1ab/nsp12844V844LGtaTta1313B.1.1770.000171
ORF1ab/nsp12844V844LGtaTta1111AY.1030.000068
ORF1ab/nsp12844V844LGtaTta1010B.1.1.70.000009
ORF1ab/nsp12844V844LGtaTta99AY.430.00004
ORF1ab/nsp12844V844LGtaTta88AY.40.000012
ORF1ab/nsp12844V844LGtaTta66AY.250.000036
ORF1ab/nsp12844V844LGtaTta55B.1.5650.004052
ORF1ab/nsp12844V844LGtaTta44AY.30.00004
ORF1ab/nsp12844V844LGtaTta44AY.390.000099
ORF1ab/nsp12844V844LGtaTta44AY.98.10.000194
ORF1ab/nsp12844V844LGtaTta24B.10.000018
ORF1ab/nsp12844V844LGtaCta24B.10.000018
ORF1ab/nsp12844V844LGtaTta33B.1.10.000054
ORF1ab/nsp12844V844LGtaTta33B.1.617.20.000011
ORF1ab/nsp12844V844LGtaTta22AY.99.20.000184
ORF1ab/nsp12844V844LGtaTta22B.1.3510.000059
ORF1ab/nsp12844V844LGtaTta22B.1.4000.000858
ORF1ab/nsp12844V844LGtaTta11AY.1180.000063
ORF1ab/nsp12844V844LGtaTta11AY.1200.000037
ORF1ab/nsp12844V844LGtACtG11AY.120.10.000321
ORF1ab/nsp12844V844LGtaTta11AY.290.000016
ORF1ab/nsp12844V844LGtaTta11AY.440.000006
ORF1ab/nsp12844V844LGtaTta11AY.50.000021
ORF1ab/nsp12844V844LGtaTta11AY.5.30.000337
ORF1ab/nsp12844V844LGtaTta11AZ.10.000867
ORF1ab/nsp12844V844LGtaCta11B.1.1.10.000327
ORF1ab/nsp12844V844LGtaTta11B.1.1.2630.001558
ORF1ab/nsp12844V844LGtaTta11B.1.1.5190.00004
ORF1ab/nsp12844V844LGtaTta11B.1.177.190.001431
ORF1ab/nsp12844V844LGtaTta11B.1.2390.001221
ORF1ab/nsp12844V844LGtaTta11B.1.2430.00007
ORF1ab/nsp12844V844LGtaTta11B.1.4030.003268
ORF1ab/nsp12844V844LGtaTta11B.1.4280.00102
ORF1ab/nsp12844V844LGtaTta11B.1.5970.00463
ORF1ab/nsp12844V844LGtaTta11B.1.6370.000073
ORF1ab/nsp12844V844LGtaTta11P.10.000016
ORF1ab/nsp12844V844LGtaTta11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.