CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V742V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12742V742VV5134VsyngtGgtT4172990.71702615664-15666
ORF1ab/nsp12742V742VV5134VsyngtGgtA417990.2374115664-15666
ORF1ab/nsp12742V742VV5134VsyngtGgtC417190.045563515664-15666

Details of the mutation V742V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12742V742VgtGgtT299417All0.000057
ORF1ab/nsp12742V742VgtGgtA99417All0.000019
ORF1ab/nsp12742V742VgtGgtC19417All0.000004
ORF1ab/nsp12742V742VgtGgtT137140B.1.1.70.000123
ORF1ab/nsp12742V742VgtGgtC2140B.1.1.70.000002
ORF1ab/nsp12742V742VgtGgtA1140B.1.1.70.000001
ORF1ab/nsp12742V742VgtGgtT6666AY.39.10.002614
ORF1ab/nsp12742V742VgtGgtT2633AY.40.00004
ORF1ab/nsp12742V742VgtGgtA533AY.40.000008
ORF1ab/nsp12742V742VgtGgtC233AY.40.000003
ORF1ab/nsp12742V742VgtGgtA1717B.1.4090.013281
ORF1ab/nsp12742V742VgtGgtA1616B.1.1.3301
ORF1ab/nsp12742V742VgtGgtT1415AY.430.000062
ORF1ab/nsp12742V742VgtGgtA115AY.430.000004
ORF1ab/nsp12742V742VgtGgtC710B.1.1770.000092
ORF1ab/nsp12742V742VgtGgtT310B.1.1770.00004
ORF1ab/nsp12742V742VgtGgtA610B.1.617.20.000023
ORF1ab/nsp12742V742VgtGgtT410B.1.617.20.000015
ORF1ab/nsp12742V742VgtGgtT58B.1.10.000091
ORF1ab/nsp12742V742VgtGgtA38B.1.10.000054
ORF1ab/nsp12742V742VgtGgtT66AY.1030.000037
ORF1ab/nsp12742V742VgtGgtA36B.10.000027
ORF1ab/nsp12742V742VgtGgtT36B.10.000027
ORF1ab/nsp12742V742VgtGgtA46B.1.4290.000094
ORF1ab/nsp12742V742VgtGgtT26B.1.4290.000047
ORF1ab/nsp12742V742VgtGgtA55B.1.1.3960.227273
ORF1ab/nsp12742V742VgtGgtA45B.1.20.000035
ORF1ab/nsp12742V742VgtGgtC15B.1.20.000009
ORF1ab/nsp12742V742VgtGgtA44AY.370.001264
ORF1ab/nsp12742V742VgtGgtC24AY.4.20.000043
ORF1ab/nsp12742V742VgtGgtA14AY.4.20.000022
ORF1ab/nsp12742V742VgtGgtT14AY.4.20.000022
ORF1ab/nsp12742V742VgtGgtT24AY.470.000062
ORF1ab/nsp12742V742VgtGgtA24AY.470.000062
ORF1ab/nsp12742V742VgtGgtC44AY.520.003257
ORF1ab/nsp12742V742VgtGgtT44B.1.1110.0047
ORF1ab/nsp12742V742VgtGgtA33AY.1020.00008
ORF1ab/nsp12742V742VgtGgtT33AY.200.000117
ORF1ab/nsp12742V742VgtGgtA33AY.440.000018
ORF1ab/nsp12742V742VgtGgtT33B.1.1600.000094
ORF1ab/nsp12742V742VgtGgtA33B.1.258.170.000312
ORF1ab/nsp12742V742VgtGgtA23D.20.00015
ORF1ab/nsp12742V742VgtGgtT13D.20.000075
ORF1ab/nsp12742V742VgtGgtT22AY.1190.000071
ORF1ab/nsp12742V742VgtGgtA22B.1.177.120.000303
ORF1ab/nsp12742V742VgtGgtT12B.1.2210.000071
ORF1ab/nsp12742V742VgtGgtA12B.1.2210.000071
ORF1ab/nsp12742V742VgtGgtT12B.1.5260.000024
ORF1ab/nsp12742V742VgtGgtA12B.1.5260.000024
ORF1ab/nsp12742V742VgtGgtT11AY.1130.000142
ORF1ab/nsp12742V742VgtGgtA11AY.1180.000063
ORF1ab/nsp12742V742VgtGgtA11AY.250.000006
ORF1ab/nsp12742V742VgtGgtA11AY.260.000028
ORF1ab/nsp12742V742VgtGgtT11AY.290.000016
ORF1ab/nsp12742V742VgtGgtA11AY.30.00001
ORF1ab/nsp12742V742VgtGgtT11AY.390.000025
ORF1ab/nsp12742V742VgtGgtT11AY.39.1.10.000725
ORF1ab/nsp12742V742VgtGgtT11AY.460.000104
ORF1ab/nsp12742V742VgtGgtT11AY.60.000041
ORF1ab/nsp12742V742VgtGgtT11AY.610.000105
ORF1ab/nsp12742V742VgtGgtA11AY.920.000287
ORF1ab/nsp12742V742VgtGgtC11B.1.1.3060.000438
ORF1ab/nsp12742V742VgtGgtT11B.1.1.330.000421
ORF1ab/nsp12742V742VgtGgtA11B.1.1.3750.011905
ORF1ab/nsp12742V742VgtGgtT11B.1.1.620.027027
ORF1ab/nsp12742V742VgtGgtA11B.1.221.10.002907
ORF1ab/nsp12742V742VgtGgtA11B.1.2320.000537
ORF1ab/nsp12742V742VgtGgtT11B.1.3510.00003
ORF1ab/nsp12742V742VgtGgtT11B.1.4250.002994
ORF1ab/nsp12742V742VgtGgtA11B.1.4320.011236
ORF1ab/nsp12742V742VgtGgtT11B.1.4680.005714
ORF1ab/nsp12742V742VgtGgtT11B.1.5170.000427
ORF1ab/nsp12742V742VgtGgtA11B.1.5820.000491
ORF1ab/nsp12742V742VgtGgtT11B.1.5960.000087
ORF1ab/nsp12742V742VgtGgtA11B.3.10.001658
ORF1ab/nsp12742V742VgtGgtT11B.60.00091
ORF1ab/nsp12742V742VgtGgtA11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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