CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V742L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12742V742LV5134LnonsynGtgTtg3723670.98655915664-15666
ORF1ab/nsp12742V742LV5134LnonsynGtgCtg37250.013440915664-15666

Details of the mutation V742L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12742V742LGtgTtg367372All0.00007
ORF1ab/nsp12742V742LGtgCtg5372All0.000001
ORF1ab/nsp12742V742LGtgTtg138138AY.140.012146
ORF1ab/nsp12742V742LGtgTtg4244B.1.1.70.000038
ORF1ab/nsp12742V742LGtgCtg244B.1.1.70.000002
ORF1ab/nsp12742V742LGtgTtg3030B.1.617.20.000113
ORF1ab/nsp12742V742LGtgTtg2222AY.440.000134
ORF1ab/nsp12742V742LGtgTtg1616AY.40.000025
ORF1ab/nsp12742V742LGtgTtg1111B.1.1600.000343
ORF1ab/nsp12742V742LGtgTtg1010AY.260.000283
ORF1ab/nsp12742V742LGtgTtg99AY.1030.000056
ORF1ab/nsp12742V742LGtgTtg88AY.690.001493
ORF1ab/nsp12742V742LGtgTtg66B.1.1.500.004073
ORF1ab/nsp12742V742LGtgTtg55AY.1020.000133
ORF1ab/nsp12742V742LGtgTtg55AY.350.001165
ORF1ab/nsp12742V742LGtgTtg55AY.430.000022
ORF1ab/nsp12742V742LGtgTtg44AY.470.000124
ORF1ab/nsp12742V742LGtgTtg44B.1.20.000035
ORF1ab/nsp12742V742LGtgTtg44B.1.3510.000119
ORF1ab/nsp12742V742LGtgTtg33AY.250.000018
ORF1ab/nsp12742V742LGtgTtg33AY.380.001498
ORF1ab/nsp12742V742LGtgTtg33AY.390.000074
ORF1ab/nsp12742V742LGtgTtg33AY.980.000237
ORF1ab/nsp12742V742LGtgTtg33B.10.000027
ORF1ab/nsp12742V742LGtgTtg23P.10.000032
ORF1ab/nsp12742V742LGtgCtg13P.10.000016
ORF1ab/nsp12742V742LGtgTtg22AY.190.002281
ORF1ab/nsp12742V742LGtgTtg22AY.540.000191
ORF1ab/nsp12742V742LGtgTtg22B.1.10.000036
ORF1ab/nsp12742V742LGtgTtg11A.10.000282
ORF1ab/nsp12742V742LGtgTtg11AY.1160.000287
ORF1ab/nsp12742V742LGtgTtg11AY.270.000065
ORF1ab/nsp12742V742LGtgTtg11AY.290.000016
ORF1ab/nsp12742V742LGtgTtg11AY.30.00001
ORF1ab/nsp12742V742LGtgTtg11AY.420.00004
ORF1ab/nsp12742V742LGtgTtg11AY.460.000104
ORF1ab/nsp12742V742LGtgTtg11AY.50.000021
ORF1ab/nsp12742V742LGtgTtg11AY.610.000105
ORF1ab/nsp12742V742LGtgTtg11AY.75.10.00018
ORF1ab/nsp12742V742LGtgTtg11AY.770.001127
ORF1ab/nsp12742V742LGtgTtg11AY.840.000437
ORF1ab/nsp12742V742LGtgTtg11AY.90.000068
ORF1ab/nsp12742V742LGtgTtg11AY.970.001701
ORF1ab/nsp12742V742LGtgTtg11B.1.1.3170.000412
ORF1ab/nsp12742V742LGtgTtg11B.1.1.3690.000446
ORF1ab/nsp12742V742LGtgTtg11B.1.1.890.006061
ORF1ab/nsp12742V742LGtgTtg11B.1.110.30.000718
ORF1ab/nsp12742V742LGtgTtg11B.1.1260.001276
ORF1ab/nsp12742V742LGtgCtg11B.1.177.440.000519
ORF1ab/nsp12742V742LGtgCtg11B.1.177.830.001481
ORF1ab/nsp12742V742LGtgTtg11B.1.2580.000067
ORF1ab/nsp12742V742LGtgTtg11B.1.4000.000429
ORF1ab/nsp12742V742LGtgTtg11B.1.4270.00005
ORF1ab/nsp12742V742LGtgTtg11B.1.5260.000024
ORF1ab/nsp12742V742LGtgTtg11B.1.6230.000536
ORF1ab/nsp12742V742LGtgTtg11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.