CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V720I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12720V720IV5112InonsynGtcAtc25309253070.99992115598-15600
ORF1ab/nsp12720V720IV5112InonsynGtCAtT2530920.000079023315598-15600

Details of the mutation V720I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12720V720IGtcAtc2530725309All0.00484
ORF1ab/nsp12720V720IGtCAtT225309All0
ORF1ab/nsp12720V720IGtcAtc1040410404B.1.2580.692354
ORF1ab/nsp12720V720IGtcAtc95759575B.1.258.170.995529
ORF1ab/nsp12720V720IGtcAtc24772477B.1.258.110.981768
ORF1ab/nsp12720V720IGtcAtc523523B.1.258.71
ORF1ab/nsp12720V720IGtcAtc374374B.1.258.220.997333
ORF1ab/nsp12720V720IGtcAtc290290B.1.258.41
ORF1ab/nsp12720V720IGtcAtc268268B.10.002455
ORF1ab/nsp12720V720IGtcAtc200200B.1.258.91
ORF1ab/nsp12720V720IGtcAtc141141B.1.258.191
ORF1ab/nsp12720V720IGtcAtc129129B.1.258.211
ORF1ab/nsp12720V720IGtcAtc125125B.1.258.120.984252
ORF1ab/nsp12720V720IGtcAtc114114B.1.258.51
ORF1ab/nsp12720V720IGtcAtc8787B.1.258.100.988636
ORF1ab/nsp12720V720IGtcAtc6363B.1.258.201
ORF1ab/nsp12720V720IGtcAtc5151B.1.258.61
ORF1ab/nsp12720V720IGtcAtc4848B.1.1600.001497
ORF1ab/nsp12720V720IGtcAtc4242B.1.258.231
ORF1ab/nsp12720V720IGtcAtc4141AY.750.002297
ORF1ab/nsp12720V720IGtcAtc3535B.1.1770.000461
ORF1ab/nsp12720V720IGtcAtc3131B.1.258.240.333333
ORF1ab/nsp12720V720IGtcAtc2828B.1.10.000508
ORF1ab/nsp12720V720IGtcAtc2727B.1.6090.012943
ORF1ab/nsp12720V720IGtcAtc2222AY.40.000034
ORF1ab/nsp12720V720IGtcAtc1313B.1.258.140.012745
ORF1ab/nsp12720V720IGtcAtc1112B.1.1.70.00001
ORF1ab/nsp12720V720IGtCAtT112B.1.1.70.000001
ORF1ab/nsp12720V720IGtcAtc1010AY.260.000283
ORF1ab/nsp12720V720IGtcAtc1010B.1.258.181
ORF1ab/nsp12720V720IGtcAtc99AY.116.10.002803
ORF1ab/nsp12720V720IGtcAtc88AY.1030.00005
ORF1ab/nsp12720V720IGtcAtc88B.1.177.860.001468
ORF1ab/nsp12720V720IGtcAtc88B.1.2430.000557
ORF1ab/nsp12720V720IGtcAtc77A0.002709
ORF1ab/nsp12720V720IGtcAtc77AY.440.000043
ORF1ab/nsp12720V720IGtcAtc77B.1.2210.000497
ORF1ab/nsp12720V720IGtcAtc77B.4.10.132075
ORF1ab/nsp12720V720IGtcAtc66B0.000767
ORF1ab/nsp12720V720IGtcAtc66B.1.177.730.003398
ORF1ab/nsp12720V720IGtcAtc66B.1.2220.010152
ORF1ab/nsp12720V720IGtcAtc66B.1.3750.004918
ORF1ab/nsp12720V720IGtcAtc55B.1.4110.018519
ORF1ab/nsp12720V720IGtcAtc55B.1.6000.02924
ORF1ab/nsp12720V720IGtcAtc44B.1.177.440.002076
ORF1ab/nsp12720V720IGtcAtc44B.1.177.60.003906
ORF1ab/nsp12720V720IGtcAtc33AY.250.000018
ORF1ab/nsp12720V720IGtcAtc33AY.430.000013
ORF1ab/nsp12720V720IGtcAtc33B.1.258.150.056604
ORF1ab/nsp12720V720IGtcAtc220.111111
ORF1ab/nsp12720V720IGtcAtc22AY.390.000049
ORF1ab/nsp12720V720IGtcAtc22AY.39.20.003082
ORF1ab/nsp12720V720IGtCAtT12AY.420.00004
ORF1ab/nsp12720V720IGtcAtc12AY.420.00004
ORF1ab/nsp12720V720IGtcAtc22B.1.1.1530.002191
ORF1ab/nsp12720V720IGtcAtc22B.1.1.390.001019
ORF1ab/nsp12720V720IGtcAtc22B.1.177.170.001642
ORF1ab/nsp12720V720IGtcAtc22B.1.177.210.000153
ORF1ab/nsp12720V720IGtcAtc22B.1.5900.009091
ORF1ab/nsp12720V720IGtcAtc22B.1.617.20.000008
ORF1ab/nsp12720V720IGtcAtc11A.2.50.000499
ORF1ab/nsp12720V720IGtcAtc11AY.1080.001103
ORF1ab/nsp12720V720IGtcAtc11AY.1130.000142
ORF1ab/nsp12720V720IGtcAtc11AY.190.00114
ORF1ab/nsp12720V720IGtcAtc11AY.30.00001
ORF1ab/nsp12720V720IGtcAtc11AY.4.20.000022
ORF1ab/nsp12720V720IGtcAtc11AY.46.40.000165
ORF1ab/nsp12720V720IGtcAtc11AY.5.30.000337
ORF1ab/nsp12720V720IGtcAtc11AY.540.000095
ORF1ab/nsp12720V720IGtcAtc11AY.920.000287
ORF1ab/nsp12720V720IGtcAtc11B.1.1.500.000679
ORF1ab/nsp12720V720IGtcAtc11B.1.1570.002985
ORF1ab/nsp12720V720IGtcAtc11B.1.177.120.000152
ORF1ab/nsp12720V720IGtcAtc11B.1.177.420.000894
ORF1ab/nsp12720V720IGtcAtc11B.1.177.70.000165
ORF1ab/nsp12720V720IGtcAtc11B.1.177.750.001041
ORF1ab/nsp12720V720IGtcAtc11B.1.20.000009
ORF1ab/nsp12720V720IGtcAtc11B.1.2370.004975
ORF1ab/nsp12720V720IGtcAtc11B.1.2410.000812
ORF1ab/nsp12720V720IGtcAtc11B.1.258.160.001637
ORF1ab/nsp12720V720IGtcAtc11B.1.258.30.001675
ORF1ab/nsp12720V720IGtcAtc11B.1.2930.0125
ORF1ab/nsp12720V720IGtcAtc11B.1.3260.007576
ORF1ab/nsp12720V720IGtcAtc11B.1.3370.005587
ORF1ab/nsp12720V720IGtcAtc11B.1.3620.001541
ORF1ab/nsp12720V720IGtcAtc11B.1.3670.000792
ORF1ab/nsp12720V720IGtcAtc11B.1.4060.006061
ORF1ab/nsp12720V720IGtcAtc11B.1.4160.001269
ORF1ab/nsp12720V720IGtcAtc11B.1.4320.011236
ORF1ab/nsp12720V720IGtcAtc11B.1.5510.00129
ORF1ab/nsp12720V720IGtcAtc11B.1.5610.000397
ORF1ab/nsp12720V720IGtcAtc11B.1.5760.000907
ORF1ab/nsp12720V720IGtcAtc11B.1.5960.000087
ORF1ab/nsp12720V720IGtcAtc11B.1.5990.00365
ORF1ab/nsp12720V720IGtcAtc11B.6.60.000889
ORF1ab/nsp12720V720IGtcAtc11C.370.000116
ORF1ab/nsp12720V720IGtcAtc11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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