CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V257F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12257V257FV4649FnonsynGttTtt575257510.99982614209-14211
ORF1ab/nsp12257V257FV4649FnonsynGtTTtC575210.00017385314209-14211

Details of the mutation V257F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12257V257FGttTtt57515752All0.0011
ORF1ab/nsp12257V257FGtTTtC15752All0
ORF1ab/nsp12257V257FGttTtt21852185AY.4.40.894026
ORF1ab/nsp12257V257FGttTtt842842AY.40.001311
ORF1ab/nsp12257V257FGttTtt416416AY.220.870293
ORF1ab/nsp12257V257FGttTtt358358B.1.1.70.00032
ORF1ab/nsp12257V257FGttTtt172172AY.430.000762
ORF1ab/nsp12257V257FGttTtt149149B.1.617.20.000561
ORF1ab/nsp12257V257FGttTtt123123B.10.001127
ORF1ab/nsp12257V257FGttTtt114114AY.200.004431
ORF1ab/nsp12257V257FGttTtt100100B.1.1770.001317
ORF1ab/nsp12257V257FGttTtt9999AY.30.000985
ORF1ab/nsp12257V257FGttTtt8686AY.580.07804
ORF1ab/nsp12257V257FGttTtt8484AY.3.10.007162
ORF1ab/nsp12257V257FGttTtt5858AY.490.185304
ORF1ab/nsp12257V257FGttTtt5757B.1.20.000502
ORF1ab/nsp12257V257FGttTtt5555B.1.2210.003907
ORF1ab/nsp12257V257FGttTtt4242AY.1030.000261
ORF1ab/nsp12257V257FGttTtt4141AY.1020.001087
ORF1ab/nsp12257V257FGttTtt3333P.10.00052
ORF1ab/nsp12257V257FGttTtt3131AY.1140.007164
ORF1ab/nsp12257V257FGttTtt3030B.1.10.000544
ORF1ab/nsp12257V257FGttTtt3030B.1.4010.245902
ORF1ab/nsp12257V257FGttTtt2727AY.440.000164
ORF1ab/nsp12257V257FGttTtt2626B.1.1.2690.035183
ORF1ab/nsp12257V257FGttTtt2121AY.250.000126
ORF1ab/nsp12257V257FGttTtt2020B.1.110.30.014368
ORF1ab/nsp12257V257FGttTtt1919AY.1200.000706
ORF1ab/nsp12257V257FGttTtt1414AY.50.000289
ORF1ab/nsp12257V257FGttTtt1414AY.90.000946
ORF1ab/nsp12257V257FGttTtt1313AY.120.004109
ORF1ab/nsp12257V257FGttTtt1313B.1.2390.015873
ORF1ab/nsp12257V257FGttTtt1212B.1.1.4480.02439
ORF1ab/nsp12257V257FGttTtt1212B.1.2580.000799
ORF1ab/nsp12257V257FGttTtt1212B.1.3510.000357
ORF1ab/nsp12257V257FGttTtt1111B.1.1.2220.002244
ORF1ab/nsp12257V257FGttTtt1010AY.420.000402
ORF1ab/nsp12257V257FGttTtt1010AY.9.20.000367
ORF1ab/nsp12257V257FGttTtt99AY.390.000222
ORF1ab/nsp12257V257FGttTtt88B.1.1.1870.070796
ORF1ab/nsp12257V257FGttTtt88B.1.177.360.129032
ORF1ab/nsp12257V257FGttTtt88B.1.3260.060606
ORF1ab/nsp12257V257FGttTtt88B.1.4290.000188
ORF1ab/nsp12257V257FGttTtt88C.370.000929
ORF1ab/nsp12257V257FGttTtt77AY.1060.002344
ORF1ab/nsp12257V257FGttTtt77B.1.1610.12069
ORF1ab/nsp12257V257FGttTtt77B.1.2180.036082
ORF1ab/nsp12257V257FGttTtt77P.1.20.008092
ORF1ab/nsp12257V257FGttTtt66AY.1210.000812
ORF1ab/nsp12257V257FGttTtt66AY.330.000401
ORF1ab/nsp12257V257FGttTtt66AY.610.000629
ORF1ab/nsp12257V257FGttTtt66B.1.1.1860.020619
ORF1ab/nsp12257V257FGttTtt66B.1.1600.000187
ORF1ab/nsp12257V257FGttTtt66B.1.177.750.006243
ORF1ab/nsp12257V257FGttTtt66B.1.5960.000523
ORF1ab/nsp12257V257FGttTtt55AY.460.00052
ORF1ab/nsp12257V257FGttTtt55AY.470.000156
ORF1ab/nsp12257V257FGttTtt55AY.860.004149
ORF1ab/nsp12257V257FGttTtt55AY.980.000395
ORF1ab/nsp12257V257FGttTtt55B.1.1.2320.009074
ORF1ab/nsp12257V257FGttTtt55B.1.1.5230.007812
ORF1ab/nsp12257V257FGttTtt55B.1.1460.021186
ORF1ab/nsp12257V257FGttTtt55B.1.5260.000118
ORF1ab/nsp12257V257FGttTtt55P.1.140.000239
ORF1ab/nsp12257V257FGttTtt44AY.370.001264
ORF1ab/nsp12257V257FGttTtt44AY.4.20.000087
ORF1ab/nsp12257V257FGttTtt44AY.680.001095
ORF1ab/nsp12257V257FGttTtt44AY.770.00451
ORF1ab/nsp12257V257FGttTtt44AY.780.006163
ORF1ab/nsp12257V257FGttTtt44B.1.1.5190.000159
ORF1ab/nsp12257V257FGttTtt44B.1.1.630.001543
ORF1ab/nsp12257V257FGttTtt44B.1.177.40.000844
ORF1ab/nsp12257V257FGttTtt44B.1.2340.000528
ORF1ab/nsp12257V257FGttTtt44B.1.2430.000278
ORF1ab/nsp12257V257FGttTtt44B.1.4270.000202
ORF1ab/nsp12257V257FGttTtt44B.1.5950.001044
ORF1ab/nsp12257V257FGttTtt44B.1.6210.000354
ORF1ab/nsp12257V257FGttTtt44C.160.004242
ORF1ab/nsp12257V257FGttTtt33AY.1000.000138
ORF1ab/nsp12257V257FGttTtt33AY.1160.00086
ORF1ab/nsp12257V257FGttTtt33AY.450.000365
ORF1ab/nsp12257V257FGttTtt33AY.46.40.000494
ORF1ab/nsp12257V257FGttTtt33AY.46.60.000217
ORF1ab/nsp12257V257FGttTtt33AY.550.002752
ORF1ab/nsp12257V257FGttTtt33AY.750.000168
ORF1ab/nsp12257V257FGttTtt33B.1.1.480.008621
ORF1ab/nsp12257V257FGttTtt33B.1.2190.028302
ORF1ab/nsp12257V257FGttTtt33B.1.351.30.002629
ORF1ab/nsp12257V257FGttTtt33C.36.10.012448
ORF1ab/nsp12257V257FGttTtt33P.20.00056
ORF1ab/nsp12257V257FGttTtt33R.10.00027
ORF1ab/nsp12257V257FGtTTtC120.055556
ORF1ab/nsp12257V257FGttTtt120.055556
ORF1ab/nsp12257V257FGttTtt22A0.000774
ORF1ab/nsp12257V257FGttTtt22A.2.50.000998
ORF1ab/nsp12257V257FGttTtt22A.230.021053
ORF1ab/nsp12257V257FGttTtt22AY.1130.000285
ORF1ab/nsp12257V257FGttTtt22AY.1150.010417
ORF1ab/nsp12257V257FGttTtt22AY.1180.000125
ORF1ab/nsp12257V257FGttTtt22AY.1190.000071
ORF1ab/nsp12257V257FGttTtt22AY.230.000139
ORF1ab/nsp12257V257FGttTtt22AY.260.000057
ORF1ab/nsp12257V257FGttTtt22AY.290.000032
ORF1ab/nsp12257V257FGttTtt22AY.340.000194
ORF1ab/nsp12257V257FGttTtt22AY.350.000466
ORF1ab/nsp12257V257FGttTtt22AY.360.000296
ORF1ab/nsp12257V257FGttTtt22AY.5.40.000553
ORF1ab/nsp12257V257FGttTtt22AY.560.00321
ORF1ab/nsp12257V257FGttTtt22AY.60.000082
ORF1ab/nsp12257V257FGttTtt22AY.600.001876
ORF1ab/nsp12257V257FGttTtt22AY.690.000373
ORF1ab/nsp12257V257FGttTtt22AY.710.00095
ORF1ab/nsp12257V257FGttTtt22AY.9.10.000167
ORF1ab/nsp12257V257FGttTtt22AY.920.000575
ORF1ab/nsp12257V257FGttTtt22AY.98.10.000097
ORF1ab/nsp12257V257FGttTtt22AY.99.20.000184
ORF1ab/nsp12257V257FGttTtt22B.1.1.1890.003026
ORF1ab/nsp12257V257FGttTtt22B.1.1.2140.000111
ORF1ab/nsp12257V257FGttTtt22B.1.1.2160.001781
ORF1ab/nsp12257V257FGttTtt22B.1.1.280.000622
ORF1ab/nsp12257V257FGttTtt22B.1.1.3160.00185
ORF1ab/nsp12257V257FGttTtt22B.1.1.4320.002532
ORF1ab/nsp12257V257FGttTtt22B.1.1.520.02439
ORF1ab/nsp12257V257FGttTtt22B.1.177.160.001329
ORF1ab/nsp12257V257FGttTtt22B.1.2670.037037
ORF1ab/nsp12257V257FGttTtt22B.1.3340.036364
ORF1ab/nsp12257V257FGttTtt22B.1.351.20.000605
ORF1ab/nsp12257V257FGttTtt22B.1.360.000292
ORF1ab/nsp12257V257FGttTtt22B.1.36.180.00084
ORF1ab/nsp12257V257FGttTtt22B.1.5750.000607
ORF1ab/nsp12257V257FGttTtt22B.1.6370.000146
ORF1ab/nsp12257V257FGttTtt22N.90.011905
ORF1ab/nsp12257V257FGttTtt22P.1.100.000539
ORF1ab/nsp12257V257FGttTtt22P.1.130.001797
ORF1ab/nsp12257V257FGttTtt22P.1.170.000324
ORF1ab/nsp12257V257FGttTtt22Q.10.000253
ORF1ab/nsp12257V257FGttTtt11A.280.002646
ORF1ab/nsp12257V257FGttTtt11AP.10.001502
ORF1ab/nsp12257V257FGttTtt11AY.100.00053
ORF1ab/nsp12257V257FGttTtt11AY.1110.000183
ORF1ab/nsp12257V257FGttTtt11AY.1170.000085
ORF1ab/nsp12257V257FGttTtt11AY.120.10.000321
ORF1ab/nsp12257V257FGttTtt11AY.16.10.00047
ORF1ab/nsp12257V257FGttTtt11AY.190.00114
ORF1ab/nsp12257V257FGttTtt11AY.240.000431
ORF1ab/nsp12257V257FGttTtt11AY.4.2.10.000149
ORF1ab/nsp12257V257FGttTtt11AY.4.50.000107
ORF1ab/nsp12257V257FGttTtt11AY.46.20.000635
ORF1ab/nsp12257V257FGttTtt11AY.46.50.000198
ORF1ab/nsp12257V257FGttTtt11AY.5.30.000337
ORF1ab/nsp12257V257FGttTtt11AY.540.000095
ORF1ab/nsp12257V257FGttTtt11AY.720.001361
ORF1ab/nsp12257V257FGttTtt11AY.740.000116
ORF1ab/nsp12257V257FGttTtt11AY.75.10.00018
ORF1ab/nsp12257V257FGttTtt11AY.820.001357
ORF1ab/nsp12257V257FGttTtt11AY.850.000427
ORF1ab/nsp12257V257FGttTtt11AY.880.000884
ORF1ab/nsp12257V257FGttTtt11AY.930.000273
ORF1ab/nsp12257V257FGttTtt11B.1.1.1610.003534
ORF1ab/nsp12257V257FGttTtt11B.1.1.1700.001247
ORF1ab/nsp12257V257FGttTtt11B.1.1.1760.000439
ORF1ab/nsp12257V257FGttTtt11B.1.1.3120.001912
ORF1ab/nsp12257V257FGttTtt11B.1.1.3180.000302
ORF1ab/nsp12257V257FGttTtt11B.1.1.330.000421
ORF1ab/nsp12257V257FGttTtt11B.1.1.3490.010309
ORF1ab/nsp12257V257FGttTtt11B.1.1.3510.002793
ORF1ab/nsp12257V257FGttTtt11B.1.1.4190.007407
ORF1ab/nsp12257V257FGttTtt11B.1.1390.000733
ORF1ab/nsp12257V257FGttTtt11B.1.160.120.00641
ORF1ab/nsp12257V257FGttTtt11B.1.177.110.001698
ORF1ab/nsp12257V257FGttTtt11B.1.177.120.000152
ORF1ab/nsp12257V257FGttTtt11B.1.177.170.000821
ORF1ab/nsp12257V257FGttTtt11B.1.177.820.000477
ORF1ab/nsp12257V257FGttTtt11B.1.1790.003759
ORF1ab/nsp12257V257FGttTtt11B.1.2410.000812
ORF1ab/nsp12257V257FGttTtt11B.1.3110.000275
ORF1ab/nsp12257V257FGttTtt11B.1.3360.002439
ORF1ab/nsp12257V257FGttTtt11B.1.3460.001311
ORF1ab/nsp12257V257FGttTtt11B.1.36.10.00114
ORF1ab/nsp12257V257FGttTtt11B.1.36.290.000517
ORF1ab/nsp12257V257FGttTtt11B.1.36.90.003215
ORF1ab/nsp12257V257FGttTtt11B.1.3750.00082
ORF1ab/nsp12257V257FGttTtt11B.1.3930.028571
ORF1ab/nsp12257V257FGttTtt11B.1.3960.000706
ORF1ab/nsp12257V257FGttTtt11B.1.4160.001269
ORF1ab/nsp12257V257FGttTtt11B.1.4220.000812
ORF1ab/nsp12257V257FGttTtt11B.1.4590.004082
ORF1ab/nsp12257V257FGttTtt11B.1.5250.000113
ORF1ab/nsp12257V257FGttTtt11B.1.5640.000426
ORF1ab/nsp12257V257FGttTtt11B.1.5900.004545
ORF1ab/nsp12257V257FGttTtt11B.1.6090.000479
ORF1ab/nsp12257V257FGttTtt11B.1.617.10.000129
ORF1ab/nsp12257V257FGttTtt11B.30.000831
ORF1ab/nsp12257V257FGttTtt11C.36.30.000567
ORF1ab/nsp12257V257FGttTtt11C.40.01
ORF1ab/nsp12257V257FGttTtt11D.20.000075
ORF1ab/nsp12257V257FGttTtt11N.40.004255
ORF1ab/nsp12257V257FGttTtt11P.1.120.000484
ORF1ab/nsp12257V257FGttTtt11P.1.150.000232
ORF1ab/nsp12257V257FGttTtt11P.1.70.000319
ORF1ab/nsp12257V257FGttTtt11P.1.80.004785
ORF1ab/nsp12257V257FGttTtt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.