CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V174V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12174V174VV4566VsyngtAgtG205420420.99415813960-13962
ORF1ab/nsp12174V174VV4566VsyngtAgtT205470.0034079813960-13962
ORF1ab/nsp12174V174VV4566VsyngtAgtC205450.0024342713960-13962

Details of the mutation V174V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12174V174VgtAgtG20422054All0.000391
ORF1ab/nsp12174V174VgtAgtT72054All0.000001
ORF1ab/nsp12174V174VgtAgtC52054All0.000001
ORF1ab/nsp12174V174VgtAgtG10951095AY.750.061345
ORF1ab/nsp12174V174VgtAgtG303303AY.9.20.011129
ORF1ab/nsp12174V174VgtAgtG169170B.1.1.70.000151
ORF1ab/nsp12174V174VgtAgtT1170B.1.1.70.000001
ORF1ab/nsp12174V174VgtAgtG116118AY.40.000181
ORF1ab/nsp12174V174VgtAgtT1118AY.40.000002
ORF1ab/nsp12174V174VgtAgtC1118AY.40.000002
ORF1ab/nsp12174V174VgtAgtG6161AY.1030.000379
ORF1ab/nsp12174V174VgtAgtG6060B.1.1.2240.857143
ORF1ab/nsp12174V174VgtAgtG2223B.1.617.20.000083
ORF1ab/nsp12174V174VgtAgtC123B.1.617.20.000004
ORF1ab/nsp12174V174VgtAgtG1717AY.4.20.000369
ORF1ab/nsp12174V174VgtAgtG1515AY.50.00031
ORF1ab/nsp12174V174VgtAgtG1414B.1.258.170.001456
ORF1ab/nsp12174V174VgtAgtG1011AY.250.00006
ORF1ab/nsp12174V174VgtAgtC111AY.250.000006
ORF1ab/nsp12174V174VgtAgtG1010AY.540.000953
ORF1ab/nsp12174V174VgtAgtG1010B.1.1770.000132
ORF1ab/nsp12174V174VgtAgtG99AY.440.000055
ORF1ab/nsp12174V174VgtAgtG78B.1.5250.000792
ORF1ab/nsp12174V174VgtAgtT18B.1.5250.000113
ORF1ab/nsp12174V174VgtAgtG77B.1.20.000062
ORF1ab/nsp12174V174VgtAgtG66AY.390.000148
ORF1ab/nsp12174V174VgtAgtG66B.10.000055
ORF1ab/nsp12174V174VgtAgtG55A0.001935
ORF1ab/nsp12174V174VgtAgtG55B.1.177.600.001092
ORF1ab/nsp12174V174VgtAgtG44AY.1130.00057
ORF1ab/nsp12174V174VgtAgtG44AY.200.000155
ORF1ab/nsp12174V174VgtAgtG44AY.290.000063
ORF1ab/nsp12174V174VgtAgtG44B.1.5680.004444
ORF1ab/nsp12174V174VgtAgtG33AY.1180.000188
ORF1ab/nsp12174V174VgtAgtG33AY.30.00003
ORF1ab/nsp12174V174VgtAgtG23AY.430.000009
ORF1ab/nsp12174V174VgtAgtT13AY.430.000004
ORF1ab/nsp12174V174VgtAgtG23AY.75.10.000361
ORF1ab/nsp12174V174VgtAgtC13AY.75.10.00018
ORF1ab/nsp12174V174VgtAgtG23B.1.10.000036
ORF1ab/nsp12174V174VgtAgtT13B.1.10.000018
ORF1ab/nsp12174V174VgtAgtG33B.1.2210.000213
ORF1ab/nsp12174V174VgtAgtG33B.1.5880.00273
ORF1ab/nsp12174V174VgtAgtG22AY.1170.000169
ORF1ab/nsp12174V174VgtAgtG22AY.1200.000074
ORF1ab/nsp12174V174VgtAgtG22AY.140.000176
ORF1ab/nsp12174V174VgtAgtG22AY.260.000057
ORF1ab/nsp12174V174VgtAgtG22AY.300.000791
ORF1ab/nsp12174V174VgtAgtG22AY.620.000871
ORF1ab/nsp12174V174VgtAgtG22AY.850.000854
ORF1ab/nsp12174V174VgtAgtG22AY.980.000158
ORF1ab/nsp12174V174VgtAgtG22B.1.1.2140.000111
ORF1ab/nsp12174V174VgtAgtG22B.1.1.2840.000215
ORF1ab/nsp12174V174VgtAgtG22B.1.177.100.001756
ORF1ab/nsp12174V174VgtAgtT22B.1.177.450.000762
ORF1ab/nsp12174V174VgtAgtG22B.1.3510.000059
ORF1ab/nsp12174V174VgtAgtG22B.1.360.000292
ORF1ab/nsp12174V174VgtAgtG22B.1.36.290.001035
ORF1ab/nsp12174V174VgtAgtG22D.20.00015
ORF1ab/nsp12174V174VgtAgtG22P.10.000032
ORF1ab/nsp12174V174VgtAgtG11AY.1000.000046
ORF1ab/nsp12174V174VgtAgtG11AY.1010.00049
ORF1ab/nsp12174V174VgtAgtG11AY.1020.000027
ORF1ab/nsp12174V174VgtAgtG11AY.1190.000035
ORF1ab/nsp12174V174VgtAgtG11AY.120.000316
ORF1ab/nsp12174V174VgtAgtG11AY.1210.000135
ORF1ab/nsp12174V174VgtAgtG11AY.240.000431
ORF1ab/nsp12174V174VgtAgtC11AY.350.000233
ORF1ab/nsp12174V174VgtAgtG11AY.470.000031
ORF1ab/nsp12174V174VgtAgtG11AY.5.40.000277
ORF1ab/nsp12174V174VgtAgtG11AY.60.000041
ORF1ab/nsp12174V174VgtAgtG11AY.640.000595
ORF1ab/nsp12174V174VgtAgtG11AY.650.000533
ORF1ab/nsp12174V174VgtAgtG11AY.680.000274
ORF1ab/nsp12174V174VgtAgtG11AY.99.20.000092
ORF1ab/nsp12174V174VgtAgtG11B.1.1.1760.000439
ORF1ab/nsp12174V174VgtAgtG11B.1.1.2940.001266
ORF1ab/nsp12174V174VgtAgtG11B.1.1.390.00051
ORF1ab/nsp12174V174VgtAgtG11B.1.177.70.000165
ORF1ab/nsp12174V174VgtAgtG11B.1.177.790.002342
ORF1ab/nsp12174V174VgtAgtG11B.1.177.850.005435
ORF1ab/nsp12174V174VgtAgtG11B.1.214.20.0006
ORF1ab/nsp12174V174VgtAgtG11B.1.2580.000067
ORF1ab/nsp12174V174VgtAgtG11B.1.36.80.001
ORF1ab/nsp12174V174VgtAgtG11B.1.4290.000024
ORF1ab/nsp12174V174VgtAgtG11B.1.5820.000491
ORF1ab/nsp12174V174VgtAgtG11B.1.595.40.007299
ORF1ab/nsp12174V174VgtAgtG11B.1.6210.000089
ORF1ab/nsp12174V174VgtAgtG11C.370.000116
ORF1ab/nsp12174V174VgtAgtG11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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