CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = V166V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12166V166VV4558VsyngtAgtG2641360.51515213936-13938
ORF1ab/nsp12166V166VV4558VsyngtAgtC264690.26136413936-13938
ORF1ab/nsp12166V166VV4558VsyngtAgtT264590.22348513936-13938

Details of the mutation V166V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12166V166VgtAgtG136264All0.000026
ORF1ab/nsp12166V166VgtAgtC69264All0.000013
ORF1ab/nsp12166V166VgtAgtT59264All0.000011
ORF1ab/nsp12166V166VgtAgtC4747B.1.1600.001466
ORF1ab/nsp12166V166VgtAgtG2738B.1.1.70.000024
ORF1ab/nsp12166V166VgtAgtC1138B.1.1.70.00001
ORF1ab/nsp12166V166VgtAgtG2533B.10.000229
ORF1ab/nsp12166V166VgtAgtC733B.10.000064
ORF1ab/nsp12166V166VgtAgtT133B.10.000009
ORF1ab/nsp12166V166VgtAgtG1317AY.40.00002
ORF1ab/nsp12166V166VgtAgtT417AY.40.000006
ORF1ab/nsp12166V166VgtAgtT1415AY.330.000935
ORF1ab/nsp12166V166VgtAgtG115AY.330.000067
ORF1ab/nsp12166V166VgtAgtT910AY.30.00009
ORF1ab/nsp12166V166VgtAgtG110AY.30.00001
ORF1ab/nsp12166V166VgtAgtG910B.1.1770.000119
ORF1ab/nsp12166V166VgtAgtC110B.1.1770.000013
ORF1ab/nsp12166V166VgtAgtG610B.1.617.20.000023
ORF1ab/nsp12166V166VgtAgtT410B.1.617.20.000015
ORF1ab/nsp12166V166VgtAgtT77AY.460.000729
ORF1ab/nsp12166V166VgtAgtG66B.1.2580.000399
ORF1ab/nsp12166V166VgtAgtG66B.1.360.000875
ORF1ab/nsp12166V166VgtAgtT450.222222
ORF1ab/nsp12166V166VgtAgtG150.055556
ORF1ab/nsp12166V166VgtAgtT55AY.440.00003
ORF1ab/nsp12166V166VgtAgtG45B.1.177.810.000757
ORF1ab/nsp12166V166VgtAgtC15B.1.177.810.000189
ORF1ab/nsp12166V166VgtAgtG44AY.250.000024
ORF1ab/nsp12166V166VgtAgtG24AY.390.000049
ORF1ab/nsp12166V166VgtAgtT24AY.390.000049
ORF1ab/nsp12166V166VgtAgtG33AY.1030.000019
ORF1ab/nsp12166V166VgtAgtG33AY.750.000168
ORF1ab/nsp12166V166VgtAgtT33B.1.1.3120.005736
ORF1ab/nsp12166V166VgtAgtG22AY.260.000057
ORF1ab/nsp12166V166VgtAgtG22AY.4.20.000043
ORF1ab/nsp12166V166VgtAgtG22AY.470.000062
ORF1ab/nsp12166V166VgtAgtG12B.1.10.000018
ORF1ab/nsp12166V166VgtAgtT12B.1.10.000018
ORF1ab/nsp12166V166VgtAgtT22B.1.617.10.000258
ORF1ab/nsp12166V166VgtAgtC12P.1.10.000318
ORF1ab/nsp12166V166VgtAgtT12P.1.10.000318
ORF1ab/nsp12166V166VgtAgtG11AY.1000.000046
ORF1ab/nsp12166V166VgtAgtG11AY.1170.000085
ORF1ab/nsp12166V166VgtAgtG11AY.140.000088
ORF1ab/nsp12166V166VgtAgtG11AY.200.000039
ORF1ab/nsp12166V166VgtAgtG11AY.290.000016
ORF1ab/nsp12166V166VgtAgtG11AY.430.000004
ORF1ab/nsp12166V166VgtAgtG11AY.46.60.000072
ORF1ab/nsp12166V166VgtAgtG11AY.50.000021
ORF1ab/nsp12166V166VgtAgtG11AY.590.00053
ORF1ab/nsp12166V166VgtAgtG11AY.90.000068
ORF1ab/nsp12166V166VgtAgtG11B.1.1.2160.00089
ORF1ab/nsp12166V166VgtAgtT11B.1.1.280.000311
ORF1ab/nsp12166V166VgtAgtG11B.1.1170.0125
ORF1ab/nsp12166V166VgtAgtC11B.1.36.80.001
ORF1ab/nsp12166V166VgtAgtG11B.1.4560.003268
ORF1ab/nsp12166V166VgtAgtG11B.1.5750.000303
ORF1ab/nsp12166V166VgtAgtG11B.1.6210.000089
ORF1ab/nsp12166V166VgtAgtG11B.1.940.027027
ORF1ab/nsp12166V166VgtAgtT11D.20.000075
ORF1ab/nsp12166V166VgtAgtG11P.10.000016
ORF1ab/nsp12166V166VgtAgtG11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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