CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = T680T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12680T680TT5072TsynacCacT820772480.88314915478-15480
ORF1ab/nsp12680T680TT5072TsynacCacA82079550.11636415478-15480
ORF1ab/nsp12680T680TT5072TsynacCacG820740.00048738915478-15480

Details of the mutation T680T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12680T680TacCacT72488207All0.001386
ORF1ab/nsp12680T680TacCacA9558207All0.000183
ORF1ab/nsp12680T680TacCacG48207All0.000001
ORF1ab/nsp12680T680TacCacT59575957B.1.177.70.982031
ORF1ab/nsp12680T680TacCacA570570AY.450.06936
ORF1ab/nsp12680T680TacCacT224253B.1.1.70.000201
ORF1ab/nsp12680T680TacCacA27253B.1.1.70.000024
ORF1ab/nsp12680T680TacCacG2253B.1.1.70.000002
ORF1ab/nsp12680T680TacCacT203208AY.440.001236
ORF1ab/nsp12680T680TacCacA5208AY.440.00003
ORF1ab/nsp12680T680TacCacT108108AY.1200.004015
ORF1ab/nsp12680T680TacCacT93100B.1.1770.001225
ORF1ab/nsp12680T680TacCacA7100B.1.1770.000092
ORF1ab/nsp12680T680TacCacT7892AY.30.000776
ORF1ab/nsp12680T680TacCacA1492AY.30.000139
ORF1ab/nsp12680T680TacCacT8383B.1.1.3170.03417
ORF1ab/nsp12680T680TacCacT5366B.1.617.20.0002
ORF1ab/nsp12680T680TacCacA1366B.1.617.20.000049
ORF1ab/nsp12680T680TacCacT4656AY.250.000277
ORF1ab/nsp12680T680TacCacA1056AY.250.00006
ORF1ab/nsp12680T680TacCacA5050AY.850.021358
ORF1ab/nsp12680T680TacCacA2448AY.40.000037
ORF1ab/nsp12680T680TacCacT2348AY.40.000036
ORF1ab/nsp12680T680TacCacG148AY.40.000002
ORF1ab/nsp12680T680TacCacT3746B.10.000339
ORF1ab/nsp12680T680TacCacA946B.10.000082
ORF1ab/nsp12680T680TacCacA3437AY.39.10.001347
ORF1ab/nsp12680T680TacCacT337AY.39.10.000119
ORF1ab/nsp12680T680TacCacT2736B.1.20.000238
ORF1ab/nsp12680T680TacCacA936B.1.20.000079
ORF1ab/nsp12680T680TacCacA3131B.1.5870.058824
ORF1ab/nsp12680T680TacCacT2829AY.1030.000174
ORF1ab/nsp12680T680TacCacA129AY.1030.000006
ORF1ab/nsp12680T680TacCacA2525AY.120.10.008026
ORF1ab/nsp12680T680TacCacT2424B.1.177.160.015947
ORF1ab/nsp12680T680TacCacT1623AY.430.000071
ORF1ab/nsp12680T680TacCacA723AY.430.000031
ORF1ab/nsp12680T680TacCacT2323B.1.2370.114428
ORF1ab/nsp12680T680TacCacA1919AY.1180.00119
ORF1ab/nsp12680T680TacCacT1116AY.1020.000292
ORF1ab/nsp12680T680TacCacA516AY.1020.000133
ORF1ab/nsp12680T680TacCacA1515AY.5.30.005061
ORF1ab/nsp12680T680TacCacT1414AY.3.10.001194
ORF1ab/nsp12680T680TacCacT1414B.1.36.90.045016
ORF1ab/nsp12680T680TacCacT1313B0.001662
ORF1ab/nsp12680T680TacCacA812AY.390.000198
ORF1ab/nsp12680T680TacCacT412AY.390.000099
ORF1ab/nsp12680T680TacCacT1111B.1.10.0002
ORF1ab/nsp12680T680TacCacA610AY.200.000233
ORF1ab/nsp12680T680TacCacT410AY.200.000155
ORF1ab/nsp12680T680TacCacT510AY.260.000142
ORF1ab/nsp12680T680TacCacA510AY.260.000142
ORF1ab/nsp12680T680TacCacT610AY.98.10.000291
ORF1ab/nsp12680T680TacCacA410AY.98.10.000194
ORF1ab/nsp12680T680TacCacT88AY.60.000329
ORF1ab/nsp12680T680TacCacT78P.10.00011
ORF1ab/nsp12680T680TacCacA18P.10.000016
ORF1ab/nsp12680T680TacCacT77AH.30.026616
ORF1ab/nsp12680T680TacCacT56A0.001935
ORF1ab/nsp12680T680TacCacA16A0.000387
ORF1ab/nsp12680T680TacCacT56AY.4.20.000108
ORF1ab/nsp12680T680TacCacA16AY.4.20.000022
ORF1ab/nsp12680T680TacCacT66B.1.1.5190.000238
ORF1ab/nsp12680T680TacCacT45AY.50.000083
ORF1ab/nsp12680T680TacCacA15AY.50.000021
ORF1ab/nsp12680T680TacCacT55B.1.1.4350.172414
ORF1ab/nsp12680T680TacCacA55C.370.00058
ORF1ab/nsp12680T680TacCacT44AY.1170.000338
ORF1ab/nsp12680T680TacCacT44AY.29.10.000882
ORF1ab/nsp12680T680TacCacT44AY.750.000224
ORF1ab/nsp12680T680TacCacA44B.1.1.330.001684
ORF1ab/nsp12680T680TacCacT44B.1.177.650.002661
ORF1ab/nsp12680T680TacCacT34B.1.4290.000071
ORF1ab/nsp12680T680TacCacA14B.1.4290.000024
ORF1ab/nsp12680T680TacCacT34B.1.5250.000339
ORF1ab/nsp12680T680TacCacA14B.1.5250.000113
ORF1ab/nsp12680T680TacCacA33AW.10.009146
ORF1ab/nsp12680T680TacCacT23AY.1130.000285
ORF1ab/nsp12680T680TacCacA13AY.1130.000142
ORF1ab/nsp12680T680TacCacA23AY.230.000139
ORF1ab/nsp12680T680TacCacT13AY.230.00007
ORF1ab/nsp12680T680TacCacA23AY.330.000134
ORF1ab/nsp12680T680TacCacT13AY.330.000067
ORF1ab/nsp12680T680TacCacA33AY.46.50.000595
ORF1ab/nsp12680T680TacCacT33B.1.1600.000094
ORF1ab/nsp12680T680TacCacT33B.1.177.150.001893
ORF1ab/nsp12680T680TacCacT33B.1.2580.0002
ORF1ab/nsp12680T680TacCacT33B.1.5610.001191
ORF1ab/nsp12680T680TacCacT33B.1.617.10.000387
ORF1ab/nsp12680T680TacCacT33B.290.010526
ORF1ab/nsp12680T680TacCacT22AY.1000.000092
ORF1ab/nsp12680T680TacCacT22AY.1140.000462
ORF1ab/nsp12680T680TacCacA22AY.270.000129
ORF1ab/nsp12680T680TacCacA22AY.420.00008
ORF1ab/nsp12680T680TacCacT22AY.46.40.000329
ORF1ab/nsp12680T680TacCacT22AY.740.000231
ORF1ab/nsp12680T680TacCacA12B.1.1.280.000311
ORF1ab/nsp12680T680TacCacT12B.1.1.280.000311
ORF1ab/nsp12680T680TacCacA22B.1.1.2940.002532
ORF1ab/nsp12680T680TacCacT22B.1.177.500.00939
ORF1ab/nsp12680T680TacCacT22B.1.177.630.005405
ORF1ab/nsp12680T680TacCacT22B.1.2430.000139
ORF1ab/nsp12680T680TacCacT22B.1.5260.000047
ORF1ab/nsp12680T680TacCacT22B.1.5950.000522
ORF1ab/nsp12680T680TacCacT22B.1.6020.013072
ORF1ab/nsp12680T680TacCacT22B.1.6210.000177
ORF1ab/nsp12680T680TacCacA110.055556
ORF1ab/nsp12680T680TacCacT11A.20.000662
ORF1ab/nsp12680T680TacCacA11A.23.10.000704
ORF1ab/nsp12680T680TacCacA11AD.20.000219
ORF1ab/nsp12680T680TacCacA11AY.1010.00049
ORF1ab/nsp12680T680TacCacT11AY.1210.000135
ORF1ab/nsp12680T680TacCacA11AY.4.30.000842
ORF1ab/nsp12680T680TacCacT11AY.4.50.000107
ORF1ab/nsp12680T680TacCacT11AY.410.000294
ORF1ab/nsp12680T680TacCacA11AY.460.000104
ORF1ab/nsp12680T680TacCacA11AY.46.60.000072
ORF1ab/nsp12680T680TacCacA11AY.520.000814
ORF1ab/nsp12680T680TacCacA11AY.620.000436
ORF1ab/nsp12680T680TacCacT11AY.810.001992
ORF1ab/nsp12680T680TacCacA11AY.9.10.000084
ORF1ab/nsp12680T680TacCacA11AY.9.20.000037
ORF1ab/nsp12680T680TacCacT11AY.91.10.004065
ORF1ab/nsp12680T680TacCacT11AY.980.000079
ORF1ab/nsp12680T680TacCacA11AY.99.20.000092
ORF1ab/nsp12680T680TacCacA11B.1.1.2070.001182
ORF1ab/nsp12680T680TacCacT11B.1.1.2570.009709
ORF1ab/nsp12680T680TacCacT11B.1.1.2710.055556
ORF1ab/nsp12680T680TacCacT11B.1.1.3060.000438
ORF1ab/nsp12680T680TacCacT11B.1.1.3110.000358
ORF1ab/nsp12680T680TacCacT11B.1.1.370.000193
ORF1ab/nsp12680T680TacCacT11B.1.1.630.000386
ORF1ab/nsp12680T680TacCacT11B.1.177.170.000821
ORF1ab/nsp12680T680TacCacT11B.1.177.60.000977
ORF1ab/nsp12680T680TacCacT11B.1.177.760.002494
ORF1ab/nsp12680T680TacCacT11B.1.2210.000071
ORF1ab/nsp12680T680TacCacT11B.1.2320.000537
ORF1ab/nsp12680T680TacCacA11B.1.2360.002053
ORF1ab/nsp12680T680TacCacT11B.1.2400.000216
ORF1ab/nsp12680T680TacCacA11B.1.3510.00003
ORF1ab/nsp12680T680TacCacA11B.1.36.350.002604
ORF1ab/nsp12680T680TacCacA11B.1.36.70.004
ORF1ab/nsp12680T680TacCacT11B.1.3620.001541
ORF1ab/nsp12680T680TacCacT11B.1.3710.001122
ORF1ab/nsp12680T680TacCacT11B.1.4200.010417
ORF1ab/nsp12680T680TacCacA11B.1.4270.00005
ORF1ab/nsp12680T680TacCacT11B.1.4730.019231
ORF1ab/nsp12680T680TacCacA11B.1.4990.00105
ORF1ab/nsp12680T680TacCacT11B.1.5480.035714
ORF1ab/nsp12680T680TacCacA11B.1.5820.000491
ORF1ab/nsp12680T680TacCacT11B.1.6090.000479
ORF1ab/nsp12680T680TacCacA11B.1.6230.000536
ORF1ab/nsp12680T680TacCacA11B.1.6250.002353
ORF1ab/nsp12680T680TacCacT11B.1.6280.000352
ORF1ab/nsp12680T680TacCacG11B.550.00295
ORF1ab/nsp12680T680TacCacA11N.10.016949
ORF1ab/nsp12680T680TacCacA11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.