CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = T246N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12246T246NT4638NnonsynaCcaAc100960.9614176-14178
ORF1ab/nsp12246T246NT4638NnonsynaCCaAT10040.0414176-14178

Details of the mutation T246N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12246T246NaCcaAc96100All0.000018
ORF1ab/nsp12246T246NaCCaAT4100All0.000001
ORF1ab/nsp12246T246NaCcaAc5353AY.1030.000329
ORF1ab/nsp12246T246NaCcaAc3434B.1.617.20.000128
ORF1ab/nsp12246T246NaCCaAT33B.1.1.630.001157
ORF1ab/nsp12246T246NaCcaAc120.055556
ORF1ab/nsp12246T246NaCCaAT120.055556
ORF1ab/nsp12246T246NaCcaAc22AY.440.000012
ORF1ab/nsp12246T246NaCcaAc22B.1.10.000036
ORF1ab/nsp12246T246NaCcaAc11AY.40.000002
ORF1ab/nsp12246T246NaCcaAc11B.10.000009
ORF1ab/nsp12246T246NaCcaAc11B.1.1.2840.000107
ORF1ab/nsp12246T246NaCcaAc11B.1.1.70.000001

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.