CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = T246A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12246T246AT4638AnonsynAccGcc16150.937514176-14178
ORF1ab/nsp12246T246AT4638AnonsynAcCGcT1610.062514176-14178

Details of the mutation T246A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12246T246AAccGcc1516All0.000003
ORF1ab/nsp12246T246AAcCGcT116All0
ORF1ab/nsp12246T246AAccGcc44B.1.1.5190.000159
ORF1ab/nsp12246T246AAccGcc44B.1.5760.003626
ORF1ab/nsp12246T246AAccGcc120.055556
ORF1ab/nsp12246T246AAcCGcT120.055556
ORF1ab/nsp12246T246AAccGcc11AY.40.000002
ORF1ab/nsp12246T246AAccGcc11AY.9.20.000037
ORF1ab/nsp12246T246AAccGcc11B.1.10.000018
ORF1ab/nsp12246T246AAccGcc11B.1.1.70.000001
ORF1ab/nsp12246T246AAccGcc11B.1.177.180.00116
ORF1ab/nsp12246T246AAccGcc11B.1.621.10.000506

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.