CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = S647I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12647S647IS5039InonsynaGcaTc57045704115379-15381

Details of the mutation S647I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12647S647IaGcaTc57045704All0.001091
ORF1ab/nsp12647S647IaGcaTc10621062AY.40.001653
ORF1ab/nsp12647S647IaGcaTc679679AY.860.563485
ORF1ab/nsp12647S647IaGcaTc475475B.1.617.20.001789
ORF1ab/nsp12647S647IaGcaTc469469B.1.1.70.00042
ORF1ab/nsp12647S647IaGcaTc309309B.1.1.3010.364387
ORF1ab/nsp12647S647IaGcaTc238238B.10.00218
ORF1ab/nsp12647S647IaGcaTc233233AY.430.001032
ORF1ab/nsp12647S647IaGcaTc130130AY.1030.000807
ORF1ab/nsp12647S647IaGcaTc110110B.1.1110.12926
ORF1ab/nsp12647S647IaGcaTc100100AY.250.000601
ORF1ab/nsp12647S647IaGcaTc8484AY.190.095781
ORF1ab/nsp12647S647IaGcaTc8484B.1.20.00074
ORF1ab/nsp12647S647IaGcaTc7979AY.440.000481
ORF1ab/nsp12647S647IaGcaTc7474B.1.1.510.127148
ORF1ab/nsp12647S647IaGcaTc6464AY.260.001812
ORF1ab/nsp12647S647IaGcaTc6363B.1.1.2160.0561
ORF1ab/nsp12647S647IaGcaTc5959B.1.416.10.092188
ORF1ab/nsp12647S647IaGcaTc5757B.1.177.210.004359
ORF1ab/nsp12647S647IaGcaTc5454B.1.10.00098
ORF1ab/nsp12647S647IaGcaTc5454B.1.4290.001271
ORF1ab/nsp12647S647IaGcaTc5050AY.980.00395
ORF1ab/nsp12647S647IaGcaTc4545AY.1020.001193
ORF1ab/nsp12647S647IaGcaTc4242AY.50.000867
ORF1ab/nsp12647S647IaGcaTc3636AY.330.002404
ORF1ab/nsp12647S647IaGcaTc3434AY.390.00084
ORF1ab/nsp12647S647IaGcaTc3333P.10.00052
ORF1ab/nsp12647S647IaGcaTc3131AY.30.000308
ORF1ab/nsp12647S647IaGcaTc3030AY.200.001166
ORF1ab/nsp12647S647IaGcaTc2828B.1.1.280.008715
ORF1ab/nsp12647S647IaGcaTc2727AY.1130.003845
ORF1ab/nsp12647S647IaGcaTc2727B.1.1.4320.034177
ORF1ab/nsp12647S647IaGcaTc2626AY.99.20.002396
ORF1ab/nsp12647S647IaGcaTc2323AY.46.60.001661
ORF1ab/nsp12647S647IaGcaTc2121B.1.1.2770.015933
ORF1ab/nsp12647S647IaGcaTc2020AY.470.000622
ORF1ab/nsp12647S647IaGcaTc1919B.1.5250.00215
ORF1ab/nsp12647S647IaGcaTc1818B.1.1.2140.000998
ORF1ab/nsp12647S647IaGcaTc1818B.1.2430.001253
ORF1ab/nsp12647S647IaGcaTc1717B.1.1770.000224
ORF1ab/nsp12647S647IaGcaTc1717B.1.617.10.002192
ORF1ab/nsp12647S647IaGcaTc1616B.1.1.3060.007014
ORF1ab/nsp12647S647IaGcaTc1515AY.360.002223
ORF1ab/nsp12647S647IaGcaTc1515AY.420.000603
ORF1ab/nsp12647S647IaGcaTc1414B.1.6330.583333
ORF1ab/nsp12647S647IaGcaTc1313AY.650.00693
ORF1ab/nsp12647S647IaGcaTc1212AU.10.01519
ORF1ab/nsp12647S647IaGcaTc1212AY.9.20.000441
ORF1ab/nsp12647S647IaGcaTc1111B.1.3510.000327
ORF1ab/nsp12647S647IaGcaTc1010AY.1080.011025
ORF1ab/nsp12647S647IaGcaTc1010AY.460.001041
ORF1ab/nsp12647S647IaGcaTc1010B.1.360.001459
ORF1ab/nsp12647S647IaGcaTc1010B.1.36.170.004941
ORF1ab/nsp12647S647IaGcaTc1010D.20.00075
ORF1ab/nsp12647S647IaGcaTc1010P.1.170.001618
ORF1ab/nsp12647S647IaGcaTc1010P.20.001866
ORF1ab/nsp12647S647IaGcaTc99AM.11
ORF1ab/nsp12647S647IaGcaTc99AY.290.000142
ORF1ab/nsp12647S647IaGcaTc99AY.540.000858
ORF1ab/nsp12647S647IaGcaTc99B.1.177.560.006008
ORF1ab/nsp12647S647IaGcaTc99B.1.5260.000212
ORF1ab/nsp12647S647IaGcaTc88AY.4.20.000174
ORF1ab/nsp12647S647IaGcaTc88AY.450.000973
ORF1ab/nsp12647S647IaGcaTc88AY.98.10.000387
ORF1ab/nsp12647S647IaGcaTc88B.1.1.3680.024691
ORF1ab/nsp12647S647IaGcaTc77AY.140.000616
ORF1ab/nsp12647S647IaGcaTc77AY.230.000488
ORF1ab/nsp12647S647IaGcaTc77AY.39.10.000277
ORF1ab/nsp12647S647IaGcaTc77AY.60.000288
ORF1ab/nsp12647S647IaGcaTc77B.1.2210.000497
ORF1ab/nsp12647S647IaGcaTc77B.1.2580.000466
ORF1ab/nsp12647S647IaGcaTc77B.1.4270.000353
ORF1ab/nsp12647S647IaGcaTc77P.1.140.000335
ORF1ab/nsp12647S647IaGcaTc66AY.1180.000376
ORF1ab/nsp12647S647IaGcaTc66AY.1200.000223
ORF1ab/nsp12647S647IaGcaTc66AY.90.000406
ORF1ab/nsp12647S647IaGcaTc66B.1.1600.000187
ORF1ab/nsp12647S647IaGcaTc66B.1.5440.036145
ORF1ab/nsp12647S647IaGcaTc66B.1.6030.06383
ORF1ab/nsp12647S647IaGcaTc55A0.001935
ORF1ab/nsp12647S647IaGcaTc55AY.1110.000916
ORF1ab/nsp12647S647IaGcaTc55AY.1190.000177
ORF1ab/nsp12647S647IaGcaTc55AY.270.000324
ORF1ab/nsp12647S647IaGcaTc55AY.560.008026
ORF1ab/nsp12647S647IaGcaTc55AY.610.000524
ORF1ab/nsp12647S647IaGcaTc55B0.000639
ORF1ab/nsp12647S647IaGcaTc55B.1.177.120.000758
ORF1ab/nsp12647S647IaGcaTc55B.1.6250.011765
ORF1ab/nsp12647S647IaGcaTc55B.1.6370.000365
ORF1ab/nsp12647S647IaGcaTc44AY.120.10.001284
ORF1ab/nsp12647S647IaGcaTc44AY.5.40.001107
ORF1ab/nsp12647S647IaGcaTc44AY.870.003331
ORF1ab/nsp12647S647IaGcaTc44B.1.1.1760.001757
ORF1ab/nsp12647S647IaGcaTc44B.1.1.2850.026144
ORF1ab/nsp12647S647IaGcaTc44B.1.1.3050.015444
ORF1ab/nsp12647S647IaGcaTc44B.1.1.3590.111111
ORF1ab/nsp12647S647IaGcaTc44B.1.1.5190.000159
ORF1ab/nsp12647S647IaGcaTc44B.1.2400.000862
ORF1ab/nsp12647S647IaGcaTc44B.1.4160.005076
ORF1ab/nsp12647S647IaGcaTc44C.370.000464
ORF1ab/nsp12647S647IaGcaTc33A.2.50.001497
ORF1ab/nsp12647S647IaGcaTc33A.23.10.002113
ORF1ab/nsp12647S647IaGcaTc33A.290.015957
ORF1ab/nsp12647S647IaGcaTc33AY.1060.001005
ORF1ab/nsp12647S647IaGcaTc33AY.1170.000254
ORF1ab/nsp12647S647IaGcaTc33AY.1210.000406
ORF1ab/nsp12647S647IaGcaTc33AY.160.001139
ORF1ab/nsp12647S647IaGcaTc33AY.4.50.000322
ORF1ab/nsp12647S647IaGcaTc33AY.400.002893
ORF1ab/nsp12647S647IaGcaTc33AY.5.30.001012
ORF1ab/nsp12647S647IaGcaTc33AY.550.002752
ORF1ab/nsp12647S647IaGcaTc33AY.70.000588
ORF1ab/nsp12647S647IaGcaTc33AY.75.10.000541
ORF1ab/nsp12647S647IaGcaTc33AY.960.006224
ORF1ab/nsp12647S647IaGcaTc33B.1.1.2910.002227
ORF1ab/nsp12647S647IaGcaTc33B.1.1.500.002037
ORF1ab/nsp12647S647IaGcaTc33B.1.30.007853
ORF1ab/nsp12647S647IaGcaTc33B.1.36.160.004274
ORF1ab/nsp12647S647IaGcaTc33B.1.4260.003027
ORF1ab/nsp12647S647IaGcaTc33B.1.4780.035294
ORF1ab/nsp12647S647IaGcaTc33B.1.6210.000266
ORF1ab/nsp12647S647IaGcaTc22AY.1000.000092
ORF1ab/nsp12647S647IaGcaTc22AY.1090.001479
ORF1ab/nsp12647S647IaGcaTc22AY.16.10.00094
ORF1ab/nsp12647S647IaGcaTc22AY.170.016393
ORF1ab/nsp12647S647IaGcaTc22AY.3.10.000171
ORF1ab/nsp12647S647IaGcaTc22AY.4.30.001684
ORF1ab/nsp12647S647IaGcaTc22AY.46.20.001271
ORF1ab/nsp12647S647IaGcaTc22AY.740.000231
ORF1ab/nsp12647S647IaGcaTc22AY.750.000112
ORF1ab/nsp12647S647IaGcaTc22AY.9.10.000167
ORF1ab/nsp12647S647IaGcaTc22AY.920.000575
ORF1ab/nsp12647S647IaGcaTc22B.1.1.2220.000408
ORF1ab/nsp12647S647IaGcaTc22B.1.1.2610.017241
ORF1ab/nsp12647S647IaGcaTc22B.1.1.3170.000823
ORF1ab/nsp12647S647IaGcaTc22B.1.1.3390.021053
ORF1ab/nsp12647S647IaGcaTc22B.1.1.3690.000892
ORF1ab/nsp12647S647IaGcaTc22B.1.1.370.000386
ORF1ab/nsp12647S647IaGcaTc22B.1.130.004751
ORF1ab/nsp12647S647IaGcaTc22B.1.177.860.000367
ORF1ab/nsp12647S647IaGcaTc22B.1.221.30.001667
ORF1ab/nsp12647S647IaGcaTc22B.1.2360.004107
ORF1ab/nsp12647S647IaGcaTc22B.1.3110.000549
ORF1ab/nsp12647S647IaGcaTc22B.1.351.20.000605
ORF1ab/nsp12647S647IaGcaTc22B.1.36.290.001035
ORF1ab/nsp12647S647IaGcaTc22B.1.36.80.002
ORF1ab/nsp12647S647IaGcaTc22B.1.4000.000858
ORF1ab/nsp12647S647IaGcaTc22B.1.4030.006536
ORF1ab/nsp12647S647IaGcaTc22B.1.5170.000854
ORF1ab/nsp12647S647IaGcaTc22B.1.5280.095238
ORF1ab/nsp12647S647IaGcaTc22B.1.5610.000794
ORF1ab/nsp12647S647IaGcaTc22B.1.5710.019417
ORF1ab/nsp12647S647IaGcaTc22B.1.6270.00404
ORF1ab/nsp12647S647IaGcaTc22C.36.30.001134
ORF1ab/nsp12647S647IaGcaTc22N.50.003534
ORF1ab/nsp12647S647IaGcaTc22P.1.150.000465
ORF1ab/nsp12647S647IaGcaTc22Q.30.00029
ORF1ab/nsp12647S647IaGcaTc22R.10.00018
ORF1ab/nsp12647S647IaGcaTc11A.20.000662
ORF1ab/nsp12647S647IaGcaTc11A.40.012821
ORF1ab/nsp12647S647IaGcaTc11AT.10.005128
ORF1ab/nsp12647S647IaGcaTc11AY.100.00053
ORF1ab/nsp12647S647IaGcaTc11AY.1050.000643
ORF1ab/nsp12647S647IaGcaTc11AY.120.2.10.000498
ORF1ab/nsp12647S647IaGcaTc11AY.130.000161
ORF1ab/nsp12647S647IaGcaTc11AY.240.000431
ORF1ab/nsp12647S647IaGcaTc11AY.29.10.000221
ORF1ab/nsp12647S647IaGcaTc11AY.34.10.00051
ORF1ab/nsp12647S647IaGcaTc11AY.4.2.10.000149
ORF1ab/nsp12647S647IaGcaTc11AY.4.40.000409
ORF1ab/nsp12647S647IaGcaTc11AY.410.000294
ORF1ab/nsp12647S647IaGcaTc11AY.46.10.001027
ORF1ab/nsp12647S647IaGcaTc11AY.46.40.000165
ORF1ab/nsp12647S647IaGcaTc11AY.590.00053
ORF1ab/nsp12647S647IaGcaTc11AY.620.000436
ORF1ab/nsp12647S647IaGcaTc11AY.7.10.000113
ORF1ab/nsp12647S647IaGcaTc11AY.820.001357
ORF1ab/nsp12647S647IaGcaTc11AY.840.000437
ORF1ab/nsp12647S647IaGcaTc11AY.850.000427
ORF1ab/nsp12647S647IaGcaTc11AY.930.000273
ORF1ab/nsp12647S647IaGcaTc11AY.990.001049
ORF1ab/nsp12647S647IaGcaTc11B.1.1.1250.010204
ORF1ab/nsp12647S647IaGcaTc11B.1.1.2040.00304
ORF1ab/nsp12647S647IaGcaTc11B.1.1.2440.015385
ORF1ab/nsp12647S647IaGcaTc11B.1.1.250.000569
ORF1ab/nsp12647S647IaGcaTc11B.1.1.270.00565
ORF1ab/nsp12647S647IaGcaTc11B.1.1.2940.001266
ORF1ab/nsp12647S647IaGcaTc11B.1.1.3180.000302
ORF1ab/nsp12647S647IaGcaTc11B.1.1.3260.001761
ORF1ab/nsp12647S647IaGcaTc11B.1.1.3740.002375
ORF1ab/nsp12647S647IaGcaTc11B.1.1.3800.009804
ORF1ab/nsp12647S647IaGcaTc11B.1.1.3970.002252
ORF1ab/nsp12647S647IaGcaTc11B.1.1.4330.001425
ORF1ab/nsp12647S647IaGcaTc11B.1.1.4480.002033
ORF1ab/nsp12647S647IaGcaTc11B.1.1.4640.001473
ORF1ab/nsp12647S647IaGcaTc11B.1.1.470.005348
ORF1ab/nsp12647S647IaGcaTc11B.1.1.590.006494
ORF1ab/nsp12647S647IaGcaTc11B.1.1030.019231
ORF1ab/nsp12647S647IaGcaTc11B.1.1260.001276
ORF1ab/nsp12647S647IaGcaTc11B.1.1570.002985
ORF1ab/nsp12647S647IaGcaTc11B.1.177.420.000894
ORF1ab/nsp12647S647IaGcaTc11B.1.177.460.000918
ORF1ab/nsp12647S647IaGcaTc11B.1.177.650.000665
ORF1ab/nsp12647S647IaGcaTc11B.1.177.730.000566
ORF1ab/nsp12647S647IaGcaTc11B.1.177.90.001332
ORF1ab/nsp12647S647IaGcaTc11B.1.221.20.004016
ORF1ab/nsp12647S647IaGcaTc11B.1.2290.009709
ORF1ab/nsp12647S647IaGcaTc11B.1.258.170.000104
ORF1ab/nsp12647S647IaGcaTc11B.1.2600.003344
ORF1ab/nsp12647S647IaGcaTc11B.1.2650.001271
ORF1ab/nsp12647S647IaGcaTc11B.1.3200.001245
ORF1ab/nsp12647S647IaGcaTc11B.1.36.180.00042
ORF1ab/nsp12647S647IaGcaTc11B.1.36.190.009259
ORF1ab/nsp12647S647IaGcaTc11B.1.36.380.001642
ORF1ab/nsp12647S647IaGcaTc11B.1.3620.001541
ORF1ab/nsp12647S647IaGcaTc11B.1.3670.000792
ORF1ab/nsp12647S647IaGcaTc11B.1.400.019608
ORF1ab/nsp12647S647IaGcaTc11B.1.4090.000781
ORF1ab/nsp12647S647IaGcaTc11B.1.4280.00102
ORF1ab/nsp12647S647IaGcaTc11B.1.438.10.000107
ORF1ab/nsp12647S647IaGcaTc11B.1.4620.007246
ORF1ab/nsp12647S647IaGcaTc11B.1.466.20.000391
ORF1ab/nsp12647S647IaGcaTc11B.1.4980.020408
ORF1ab/nsp12647S647IaGcaTc11B.1.5240.001406
ORF1ab/nsp12647S647IaGcaTc11B.1.5380.008065
ORF1ab/nsp12647S647IaGcaTc11B.1.575.10.002439
ORF1ab/nsp12647S647IaGcaTc11B.1.5760.000907
ORF1ab/nsp12647S647IaGcaTc11B.1.5770.000687
ORF1ab/nsp12647S647IaGcaTc11B.1.5910.010638
ORF1ab/nsp12647S647IaGcaTc11B.1.5950.000261
ORF1ab/nsp12647S647IaGcaTc11B.1.6280.000352
ORF1ab/nsp12647S647IaGcaTc11B.4.10.018868
ORF1ab/nsp12647S647IaGcaTc11B.400.000364
ORF1ab/nsp12647S647IaGcaTc11C.140.004329
ORF1ab/nsp12647S647IaGcaTc11C.180.002591
ORF1ab/nsp12647S647IaGcaTc11C.350.000774
ORF1ab/nsp12647S647IaGcaTc11C.400.027778
ORF1ab/nsp12647S647IaGcaTc11K.10.02381
ORF1ab/nsp12647S647IaGcaTc11P.1.120.000484
ORF1ab/nsp12647S647IaGcaTc11P.1.160.000374
ORF1ab/nsp12647S647IaGcaTc11P.1.70.000319
ORF1ab/nsp12647S647IaGcaTc11Q.10.000126
ORF1ab/nsp12647S647IaGcaTc11Q.20.000613
ORF1ab/nsp12647S647IaGcaTc11Q.80.000165
ORF1ab/nsp12647S647IaGcaTc11W.30.005263

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.