CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = P868L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12868P868LP5260LnonsyncCacTa17160.94117616042-16044
ORF1ab/nsp12868P868LP5260LnonsyncCAcTT1710.058823516042-16044

Details of the mutation P868L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12868P868LcCacTa1617All0.000003
ORF1ab/nsp12868P868LcCAcTT117All0
ORF1ab/nsp12868P868LcCacTa55B.10.000046
ORF1ab/nsp12868P868LcCacTa22AY.40.000003
ORF1ab/nsp12868P868LcCacTa22D.20.00015
ORF1ab/nsp12868P868LcCAcTT11AY.120.10.000321
ORF1ab/nsp12868P868LcCacTa11AY.130.000161
ORF1ab/nsp12868P868LcCacTa11AY.430.000004
ORF1ab/nsp12868P868LcCacTa11B0.000128
ORF1ab/nsp12868P868LcCacTa11B.1.10.000018
ORF1ab/nsp12868P868LcCacTa11B.1.1.70.000001
ORF1ab/nsp12868P868LcCacTa11B.1.20.000009
ORF1ab/nsp12868P868LcCacTa11B.1.617.20.000004

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.