CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = K91N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1291K91NK4483NnonsynaaGaaT7257000.96551713711-13713
ORF1ab/nsp1291K91NK4483NnonsynaaGaaC725250.034482813711-13713

Details of the mutation K91N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1291K91NaaGaaT700725All0.000134
ORF1ab/nsp1291K91NaaGaaC25725All0.000005
ORF1ab/nsp1291K91NaaGaaT282282AY.40.000439
ORF1ab/nsp1291K91NaaGaaT112112P.10.001764
ORF1ab/nsp1291K91NaaGaaT103103B.1.177.781
ORF1ab/nsp1291K91NaaGaaT2635B.1.1.70.000023
ORF1ab/nsp1291K91NaaGaaC935B.1.1.70.000008
ORF1ab/nsp1291K91NaaGaaT2626AY.260.000736
ORF1ab/nsp1291K91NaaGaaT2424B.1.1.390.012232
ORF1ab/nsp1291K91NaaGaaT1414B.1.617.20.000053
ORF1ab/nsp1291K91NaaGaaC99B.1.5250.001018
ORF1ab/nsp1291K91NaaGaaT88AY.250.000048
ORF1ab/nsp1291K91NaaGaaT77AY.290.00011
ORF1ab/nsp1291K91NaaGaaT77AY.390.000173
ORF1ab/nsp1291K91NaaGaaT66B.10.000055
ORF1ab/nsp1291K91NaaGaaT66B.1.10.000109
ORF1ab/nsp1291K91NaaGaaC45AY.1050.002572
ORF1ab/nsp1291K91NaaGaaT15AY.1050.000643
ORF1ab/nsp1291K91NaaGaaT55B.1.1.2820.05814
ORF1ab/nsp1291K91NaaGaaT55B.1.1770.000066
ORF1ab/nsp1291K91NaaGaaT45B.1.20.000035
ORF1ab/nsp1291K91NaaGaaC15B.1.20.000009
ORF1ab/nsp1291K91NaaGaaT44AY.430.000018
ORF1ab/nsp1291K91NaaGaaT44AY.440.000024
ORF1ab/nsp1291K91NaaGaaT44B.400.001457
ORF1ab/nsp1291K91NaaGaaT33AY.30.00003
ORF1ab/nsp1291K91NaaGaaT33B.1.36.290.001552
ORF1ab/nsp1291K91NaaGaaT33P.1.140.000143
ORF1ab/nsp1291K91NaaGaaT22AY.1190.000071
ORF1ab/nsp1291K91NaaGaaT22AY.50.000041
ORF1ab/nsp1291K91NaaGaaT22AY.690.000373
ORF1ab/nsp1291K91NaaGaaT22B.1.1.2850.013072
ORF1ab/nsp1291K91NaaGaaT22B.1.177.180.00232
ORF1ab/nsp1291K91NaaGaaT22B.1.4000.000858
ORF1ab/nsp1291K91NaaGaaT22B.1.617.10.000258
ORF1ab/nsp1291K91NaaGaaC12B.1.6360.006711
ORF1ab/nsp1291K91NaaGaaT12B.1.6360.006711
ORF1ab/nsp1291K91NaaGaaT22P.1.150.000465
ORF1ab/nsp1291K91NaaGaaT11AY.1020.000027
ORF1ab/nsp1291K91NaaGaaT11AY.1030.000006
ORF1ab/nsp1291K91NaaGaaT11AY.1070.000466
ORF1ab/nsp1291K91NaaGaaT11AY.1170.000085
ORF1ab/nsp1291K91NaaGaaT11AY.200.000039
ORF1ab/nsp1291K91NaaGaaT11AY.230.00007
ORF1ab/nsp1291K91NaaGaaT11AY.330.000067
ORF1ab/nsp1291K91NaaGaaT11AY.39.10.00004
ORF1ab/nsp1291K91NaaGaaT11AY.4.20.000022
ORF1ab/nsp1291K91NaaGaaT11AY.450.000122
ORF1ab/nsp1291K91NaaGaaT11AY.5.20.002463
ORF1ab/nsp1291K91NaaGaaC11AY.620.000436
ORF1ab/nsp1291K91NaaGaaT11AY.90.000068
ORF1ab/nsp1291K91NaaGaaT11B.1.1.10.000327
ORF1ab/nsp1291K91NaaGaaT11B.1.1.3290.003846
ORF1ab/nsp1291K91NaaGaaT11B.1.1.4160.000905
ORF1ab/nsp1291K91NaaGaaT11B.1.1.700.000341
ORF1ab/nsp1291K91NaaGaaT11B.1.214.20.0006
ORF1ab/nsp1291K91NaaGaaT11B.1.2210.000071
ORF1ab/nsp1291K91NaaGaaT11B.1.3320.003497
ORF1ab/nsp1291K91NaaGaaT11B.1.360.000146
ORF1ab/nsp1291K91NaaGaaT11B.1.4290.000024
ORF1ab/nsp1291K91NaaGaaT11B.1.438.10.000107
ORF1ab/nsp1291K91NaaGaaT11B.1.4560.003268
ORF1ab/nsp1291K91NaaGaaT11B.1.6210.000089
ORF1ab/nsp1291K91NaaGaaT11B.60.00091
ORF1ab/nsp1291K91NaaGaaT11C.170.055556

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.