CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = E744D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12744E744DE5136DnonsyngaGgaT696868590.98435715670-15672
ORF1ab/nsp12744E744DE5136DnonsyngaGgaC69681090.015642915670-15672

Details of the mutation E744D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12744E744DgaGgaT68596968All0.001312
ORF1ab/nsp12744E744DgaGgaC1096968All0.000021
ORF1ab/nsp12744E744DgaGgaT12831358B.1.1.70.001149
ORF1ab/nsp12744E744DgaGgaC751358B.1.1.70.000067
ORF1ab/nsp12744E744DgaGgaT10971098B.1.617.20.004131
ORF1ab/nsp12744E744DgaGgaC11098B.1.617.20.000004
ORF1ab/nsp12744E744DgaGgaT681683AY.430.003017
ORF1ab/nsp12744E744DgaGgaC2683AY.430.000009
ORF1ab/nsp12744E744DgaGgaT526526AY.1030.003266
ORF1ab/nsp12744E744DgaGgaT430433AY.40.000669
ORF1ab/nsp12744E744DgaGgaC3433AY.40.000005
ORF1ab/nsp12744E744DgaGgaT201201B.1.5680.223333
ORF1ab/nsp12744E744DgaGgaT193193AY.420.007764
ORF1ab/nsp12744E744DgaGgaT179179B.1.5640.076235
ORF1ab/nsp12744E744DgaGgaT176176B.1.177.70.029014
ORF1ab/nsp12744E744DgaGgaT120125AY.440.00073
ORF1ab/nsp12744E744DgaGgaC5125AY.440.00003
ORF1ab/nsp12744E744DgaGgaT9999AY.4.20.002147
ORF1ab/nsp12744E744DgaGgaT8990B.1.20.000784
ORF1ab/nsp12744E744DgaGgaC190B.1.20.000009
ORF1ab/nsp12744E744DgaGgaT7980AY.1020.002095
ORF1ab/nsp12744E744DgaGgaC180AY.1020.000027
ORF1ab/nsp12744E744DgaGgaT6969AY.1170.005832
ORF1ab/nsp12744E744DgaGgaT6262AY.290.000978
ORF1ab/nsp12744E744DgaGgaT5960P.10.000929
ORF1ab/nsp12744E744DgaGgaC160P.10.000016
ORF1ab/nsp12744E744DgaGgaT5757AY.390.001409
ORF1ab/nsp12744E744DgaGgaT5454AY.50.001115
ORF1ab/nsp12744E744DgaGgaT4949AY.250.000295
ORF1ab/nsp12744E744DgaGgaT4646B.1.6370.003361
ORF1ab/nsp12744E744DgaGgaT4444AY.9.20.001616
ORF1ab/nsp12744E744DgaGgaT4043B.1.3510.001189
ORF1ab/nsp12744E744DgaGgaC343B.1.3510.000089
ORF1ab/nsp12744E744DgaGgaT4041AY.200.001555
ORF1ab/nsp12744E744DgaGgaC141AY.200.000039
ORF1ab/nsp12744E744DgaGgaT4141AY.260.001161
ORF1ab/nsp12744E744DgaGgaT4041AY.30.000398
ORF1ab/nsp12744E744DgaGgaC141AY.30.00001
ORF1ab/nsp12744E744DgaGgaT3939AY.5.30.013158
ORF1ab/nsp12744E744DgaGgaT3737P.1.130.033243
ORF1ab/nsp12744E744DgaGgaT3636B.1.1.3550.553846
ORF1ab/nsp12744E744DgaGgaT3636B.1.177.170.029557
ORF1ab/nsp12744E744DgaGgaT3636B.1.2210.002557
ORF1ab/nsp12744E744DgaGgaT3333AY.4.40.013502
ORF1ab/nsp12744E744DgaGgaT2931B.10.000266
ORF1ab/nsp12744E744DgaGgaC231B.10.000018
ORF1ab/nsp12744E744DgaGgaT2929AY.330.001937
ORF1ab/nsp12744E744DgaGgaT2425B.1.10.000435
ORF1ab/nsp12744E744DgaGgaC125B.1.10.000018
ORF1ab/nsp12744E744DgaGgaT2424B.1.1.3690.01071
ORF1ab/nsp12744E744DgaGgaT2424B.1.4290.000565
ORF1ab/nsp12744E744DgaGgaT1919AY.1200.000706
ORF1ab/nsp12744E744DgaGgaT1919AY.470.000591
ORF1ab/nsp12744E744DgaGgaT1919AY.690.003547
ORF1ab/nsp12744E744DgaGgaT1718AY.98.10.000823
ORF1ab/nsp12744E744DgaGgaC118AY.98.10.000048
ORF1ab/nsp12744E744DgaGgaT1717AY.1190.0006
ORF1ab/nsp12744E744DgaGgaT1717B.1.177.810.003218
ORF1ab/nsp12744E744DgaGgaT1616AE.80.007824
ORF1ab/nsp12744E744DgaGgaT1616AY.1000.000736
ORF1ab/nsp12744E744DgaGgaT1616AY.770.018038
ORF1ab/nsp12744E744DgaGgaT1616B.1.177.80.012039
ORF1ab/nsp12744E744DgaGgaT1616B.1.2430.001113
ORF1ab/nsp12744E744DgaGgaT1515B.1.1770.000198
ORF1ab/nsp12744E744DgaGgaT1515B.1.3490.010722
ORF1ab/nsp12744E744DgaGgaT1313AY.460.001353
ORF1ab/nsp12744E744DgaGgaT1313AY.5.40.003597
ORF1ab/nsp12744E744DgaGgaT1313B.1.5260.000306
ORF1ab/nsp12744E744DgaGgaT1212A.23.10.008451
ORF1ab/nsp12744E744DgaGgaT1212AY.46.60.000866
ORF1ab/nsp12744E744DgaGgaT1212B.1.5311
ORF1ab/nsp12744E744DgaGgaT1111AY.450.001339
ORF1ab/nsp12744E744DgaGgaT1010AY.1210.001353
ORF1ab/nsp12744E744DgaGgaT1010AY.210.018975
ORF1ab/nsp12744E744DgaGgaT1010B.1.1600.000312
ORF1ab/nsp12744E744DgaGgaT1010B.1.2340.001319
ORF1ab/nsp12744E744DgaGgaT1010B.1.6210.000885
ORF1ab/nsp12744E744DgaGgaT99AY.39.10.000357
ORF1ab/nsp12744E744DgaGgaT99B.1.2400.00194
ORF1ab/nsp12744E744DgaGgaT99B.1.4270.000454
ORF1ab/nsp12744E744DgaGgaT99P.1.140.00043
ORF1ab/nsp12744E744DgaGgaT88B.1.466.20.00313
ORF1ab/nsp12744E744DgaGgaT77AY.60.000288
ORF1ab/nsp12744E744DgaGgaT77AY.750.000392
ORF1ab/nsp12744E744DgaGgaT77AY.900.004791
ORF1ab/nsp12744E744DgaGgaT77AY.950.005327
ORF1ab/nsp12744E744DgaGgaT77B.1.1.3770.009669
ORF1ab/nsp12744E744DgaGgaT77B.1.2580.000466
ORF1ab/nsp12744E744DgaGgaT66AY.230.000418
ORF1ab/nsp12744E744DgaGgaT36AY.75.10.000541
ORF1ab/nsp12744E744DgaGgaC36AY.75.10.000541
ORF1ab/nsp12744E744DgaGgaT66AY.9.10.000502
ORF1ab/nsp12744E744DgaGgaT66B.1.1.1630.045802
ORF1ab/nsp12744E744DgaGgaT66B.1.1.5190.000238
ORF1ab/nsp12744E744DgaGgaT66B.1.5750.00182
ORF1ab/nsp12744E744DgaGgaT55AY.1010.002452
ORF1ab/nsp12744E744DgaGgaT55AY.1180.000313
ORF1ab/nsp12744E744DgaGgaT55AY.34.10.00255
ORF1ab/nsp12744E744DgaGgaT55AY.610.000524
ORF1ab/nsp12744E744DgaGgaT55AY.90.000338
ORF1ab/nsp12744E744DgaGgaT55B.1.1.2140.000277
ORF1ab/nsp12744E744DgaGgaT55B.1.360.00073
ORF1ab/nsp12744E744DgaGgaT55B.1.5250.000566
ORF1ab/nsp12744E744DgaGgaT55P.1.150.001162
ORF1ab/nsp12744E744DgaGgaT55Q.40.002274
ORF1ab/nsp12744E744DgaGgaT44AY.1130.00057
ORF1ab/nsp12744E744DgaGgaT44AY.4.50.00043
ORF1ab/nsp12744E744DgaGgaT44B0.000511
ORF1ab/nsp12744E744DgaGgaT44B.1.1.2220.000816
ORF1ab/nsp12744E744DgaGgaT44B.1.1.3480.003185
ORF1ab/nsp12744E744DgaGgaT44B.1.110.30.002874
ORF1ab/nsp12744E744DgaGgaT33AY.1140.000693
ORF1ab/nsp12744E744DgaGgaT33AY.160.001139
ORF1ab/nsp12744E744DgaGgaT33AY.270.000194
ORF1ab/nsp12744E744DgaGgaT33AY.3.10.000256
ORF1ab/nsp12744E744DgaGgaT33AY.370.000948
ORF1ab/nsp12744E744DgaGgaT33AY.540.000286
ORF1ab/nsp12744E744DgaGgaT33AY.550.002752
ORF1ab/nsp12744E744DgaGgaT33AY.660.003209
ORF1ab/nsp12744E744DgaGgaT33AY.740.000347
ORF1ab/nsp12744E744DgaGgaT33AY.930.000819
ORF1ab/nsp12744E744DgaGgaT33AY.940.001328
ORF1ab/nsp12744E744DgaGgaT33AY.980.000237
ORF1ab/nsp12744E744DgaGgaT33AY.990.003148
ORF1ab/nsp12744E744DgaGgaT33B.1.1.2840.000322
ORF1ab/nsp12744E744DgaGgaT33B.1.177.430.004431
ORF1ab/nsp12744E744DgaGgaT33B.1.36.290.001552
ORF1ab/nsp12744E744DgaGgaT33B.1.4970.000944
ORF1ab/nsp12744E744DgaGgaT33B.1.930.002801
ORF1ab/nsp12744E744DgaGgaT33C.36.30.001702
ORF1ab/nsp12744E744DgaGgaT33P.1.100.000808
ORF1ab/nsp12744E744DgaGgaT33P.1.170.000485
ORF1ab/nsp12744E744DgaGgaT33R.10.00027
ORF1ab/nsp12744E744DgaGgaT22AY.1070.000932
ORF1ab/nsp12744E744DgaGgaT22AY.1100.000225
ORF1ab/nsp12744E744DgaGgaT22AY.1110.000366
ORF1ab/nsp12744E744DgaGgaT22AY.340.000194
ORF1ab/nsp12744E744DgaGgaT22AY.4.2.10.000298
ORF1ab/nsp12744E744DgaGgaT22AY.400.001929
ORF1ab/nsp12744E744DgaGgaT22AY.46.10.002053
ORF1ab/nsp12744E744DgaGgaT22AY.570.001312
ORF1ab/nsp12744E744DgaGgaC22AY.600.001876
ORF1ab/nsp12744E744DgaGgaT22AY.680.000547
ORF1ab/nsp12744E744DgaGgaT22AY.70.000392
ORF1ab/nsp12744E744DgaGgaT22AY.7.10.000225
ORF1ab/nsp12744E744DgaGgaT22AY.7.20.001119
ORF1ab/nsp12744E744DgaGgaT22AY.700.000417
ORF1ab/nsp12744E744DgaGgaT22AY.840.000875
ORF1ab/nsp12744E744DgaGgaT22AY.920.000575
ORF1ab/nsp12744E744DgaGgaT22B.1.1.1210.004854
ORF1ab/nsp12744E744DgaGgaT22B.1.1.250.001137
ORF1ab/nsp12744E744DgaGgaT22B.1.1.2740.010101
ORF1ab/nsp12744E744DgaGgaT22B.1.1.2790.002242
ORF1ab/nsp12744E744DgaGgaT22B.1.1.4200.002012
ORF1ab/nsp12744E744DgaGgaT22B.1.1.4320.002532
ORF1ab/nsp12744E744DgaGgaT22B.1.1.4340.000697
ORF1ab/nsp12744E744DgaGgaT22B.1.1.540.006042
ORF1ab/nsp12744E744DgaGgaT12B.1.1.630.000386
ORF1ab/nsp12744E744DgaGgaC12B.1.1.630.000386
ORF1ab/nsp12744E744DgaGgaT22B.1.1180.013423
ORF1ab/nsp12744E744DgaGgaT22B.1.177.770.001452
ORF1ab/nsp12744E744DgaGgaT22B.1.243.20.028986
ORF1ab/nsp12744E744DgaGgaT22B.1.2790.001027
ORF1ab/nsp12744E744DgaGgaT22B.1.3690.00057
ORF1ab/nsp12744E744DgaGgaT22B.1.438.10.000215
ORF1ab/nsp12744E744DgaGgaT22B.1.5990.007299
ORF1ab/nsp12744E744DgaGgaT22B.1.617.10.000258
ORF1ab/nsp12744E744DgaGgaT22B.1.6250.004706
ORF1ab/nsp12744E744DgaGgaT22B.560.057143
ORF1ab/nsp12744E744DgaGgaT22C.20.032258
ORF1ab/nsp12744E744DgaGgaT12Q.10.000126
ORF1ab/nsp12744E744DgaGgaC12Q.10.000126
ORF1ab/nsp12744E744DgaGgaT22Q.80.00033
ORF1ab/nsp12744E744DgaGgaT11A0.000387
ORF1ab/nsp12744E744DgaGgaT11A.2.40.003367
ORF1ab/nsp12744E744DgaGgaT11A.270.001656
ORF1ab/nsp12744E744DgaGgaT11A.280.002646
ORF1ab/nsp12744E744DgaGgaT11AY.10.000396
ORF1ab/nsp12744E744DgaGgaT11AY.1060.000335
ORF1ab/nsp12744E744DgaGgaT11AY.1090.00074
ORF1ab/nsp12744E744DgaGgaT11AY.1160.000287
ORF1ab/nsp12744E744DgaGgaT11AY.120.10.000321
ORF1ab/nsp12744E744DgaGgaT11AY.150.002222
ORF1ab/nsp12744E744DgaGgaT11AY.16.10.00047
ORF1ab/nsp12744E744DgaGgaT11AY.23.10.000417
ORF1ab/nsp12744E744DgaGgaT11AY.240.000431
ORF1ab/nsp12744E744DgaGgaT11AY.360.000148
ORF1ab/nsp12744E744DgaGgaT11AY.410.000294
ORF1ab/nsp12744E744DgaGgaT11AY.480.000465
ORF1ab/nsp12744E744DgaGgaT11AY.630.000387
ORF1ab/nsp12744E744DgaGgaT11AY.670.000464
ORF1ab/nsp12744E744DgaGgaT11AY.790.001211
ORF1ab/nsp12744E744DgaGgaT11AY.850.000427
ORF1ab/nsp12744E744DgaGgaT11AY.890.004902
ORF1ab/nsp12744E744DgaGgaT11B.1.1.100.001115
ORF1ab/nsp12744E744DgaGgaC11B.1.1.1380.006061
ORF1ab/nsp12744E744DgaGgaT11B.1.1.1920.002309
ORF1ab/nsp12744E744DgaGgaT11B.1.1.2070.001182
ORF1ab/nsp12744E744DgaGgaT11B.1.1.2620.015152
ORF1ab/nsp12744E744DgaGgaT11B.1.1.280.000311
ORF1ab/nsp12744E744DgaGgaT11B.1.1.2940.001266
ORF1ab/nsp12744E744DgaGgaT11B.1.1.3050.003861
ORF1ab/nsp12744E744DgaGgaC11B.1.1.3060.000438
ORF1ab/nsp12744E744DgaGgaT11B.1.1.3180.000302
ORF1ab/nsp12744E744DgaGgaT11B.1.1.3540.004386
ORF1ab/nsp12744E744DgaGgaT11B.1.1.3720.000689
ORF1ab/nsp12744E744DgaGgaT11B.1.1.390.00051
ORF1ab/nsp12744E744DgaGgaT11B.1.1.4090.002833
ORF1ab/nsp12744E744DgaGgaT11B.1.1.440.00241
ORF1ab/nsp12744E744DgaGgaT11B.1.1.500.000679
ORF1ab/nsp12744E744DgaGgaT11B.1.1.700.000341
ORF1ab/nsp12744E744DgaGgaT11B.1.1640.014925
ORF1ab/nsp12744E744DgaGgaT11B.1.1670.007812
ORF1ab/nsp12744E744DgaGgaT11B.1.177.100.000878
ORF1ab/nsp12744E744DgaGgaT11B.1.177.120.000152
ORF1ab/nsp12744E744DgaGgaC11B.1.177.320.00135
ORF1ab/nsp12744E744DgaGgaT11B.1.177.40.000211
ORF1ab/nsp12744E744DgaGgaT11B.1.177.440.000519
ORF1ab/nsp12744E744DgaGgaT11B.1.177.510.004566
ORF1ab/nsp12744E744DgaGgaT11B.1.177.570.000281
ORF1ab/nsp12744E744DgaGgaT11B.1.177.590.016129
ORF1ab/nsp12744E744DgaGgaT11B.1.177.820.000477
ORF1ab/nsp12744E744DgaGgaT11B.1.2220.001692
ORF1ab/nsp12744E744DgaGgaT11B.1.3110.000275
ORF1ab/nsp12744E744DgaGgaT11B.1.351.10.038462
ORF1ab/nsp12744E744DgaGgaT11B.1.351.20.000303
ORF1ab/nsp12744E744DgaGgaT11B.1.36.240.006173
ORF1ab/nsp12744E744DgaGgaC11B.1.3890.001002
ORF1ab/nsp12744E744DgaGgaT11B.1.3960.000706
ORF1ab/nsp12744E744DgaGgaT11B.1.4040.001302
ORF1ab/nsp12744E744DgaGgaT11B.1.4280.00102
ORF1ab/nsp12744E744DgaGgaT11B.1.4320.011236
ORF1ab/nsp12744E744DgaGgaT11B.1.4560.003268
ORF1ab/nsp12744E744DgaGgaT11B.1.5090.000866
ORF1ab/nsp12744E744DgaGgaT11B.1.5520.015152
ORF1ab/nsp12744E744DgaGgaT11B.1.5580.004566
ORF1ab/nsp12744E744DgaGgaT11B.1.5820.000491
ORF1ab/nsp12744E744DgaGgaT11B.1.5950.000261
ORF1ab/nsp12744E744DgaGgaT11B.110.005128
ORF1ab/nsp12744E744DgaGgaT11B.200.023256
ORF1ab/nsp12744E744DgaGgaT11B.6.60.000889
ORF1ab/nsp12744E744DgaGgaT11C.10.002392
ORF1ab/nsp12744E744DgaGgaT11C.1.20.004255
ORF1ab/nsp12744E744DgaGgaT11C.350.000774
ORF1ab/nsp12744E744DgaGgaT11C.370.000116
ORF1ab/nsp12744E744DgaGgaT11N.50.001767
ORF1ab/nsp12744E744DgaGgaT11P.1.10.000318
ORF1ab/nsp12744E744DgaGgaT11P.1.120.000484
ORF1ab/nsp12744E744DgaGgaT11Q.20.000613
ORF1ab/nsp12744E744DgaGgaT11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.