CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = D738Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12738D738YD5130YnonsynGacTac455945580.99978115652-15654
ORF1ab/nsp12738D738YD5130YnonsynGaCTaT455910.00021934615652-15654

Details of the mutation D738Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12738D738YGacTac45584559All0.000872
ORF1ab/nsp12738D738YGaCTaT14559All0
ORF1ab/nsp12738D738YGacTac10991099B.1.1.2770.833839
ORF1ab/nsp12738D738YGacTac917917B.1.1.70.000821
ORF1ab/nsp12738D738YGacTac258258AY.1200.009592
ORF1ab/nsp12738D738YGacTac242242AY.40.000377
ORF1ab/nsp12738D738YGacTac225225B.1.617.20.000847
ORF1ab/nsp12738D738YGacTac162162K.31
ORF1ab/nsp12738D738YGacTac136136B.10.001246
ORF1ab/nsp12738D738YGacTac9898AY.430.000434
ORF1ab/nsp12738D738YGacTac9090AY.1020.002386
ORF1ab/nsp12738D738YGacTac8888P.1.10.027954
ORF1ab/nsp12738D738YGacTac8686AY.1190.003037
ORF1ab/nsp12738D738YGacTac7878AY.600.073171
ORF1ab/nsp12738D738YGacTac7474AY.440.00045
ORF1ab/nsp12738D738YGacTac7070B.1.1770.000922
ORF1ab/nsp12738D738YGacTac6667AY.30.000656
ORF1ab/nsp12738D738YGaCTaT167AY.30.00001
ORF1ab/nsp12738D738YGacTac6262AY.250.000373
ORF1ab/nsp12738D738YGacTac6262AY.340.006012
ORF1ab/nsp12738D738YGacTac5656AY.1030.000348
ORF1ab/nsp12738D738YGacTac4141B.1.20.000361
ORF1ab/nsp12738D738YGacTac3434AY.390.00084
ORF1ab/nsp12738D738YGacTac2626AY.330.001736
ORF1ab/nsp12738D738YGacTac2424B.1.6230.012876
ORF1ab/nsp12738D738YGacTac2121AY.20.007479
ORF1ab/nsp12738D738YGacTac2121AY.290.000331
ORF1ab/nsp12738D738YGacTac2020B.1.10.000363
ORF1ab/nsp12738D738YGacTac1717AY.4.20.000369
ORF1ab/nsp12738D738YGacTac1717B.1.4290.0004
ORF1ab/nsp12738D738YGacTac1717B.1.5960.001481
ORF1ab/nsp12738D738YGacTac1717P.10.000268
ORF1ab/nsp12738D738YGacTac1616B.1.177.500.075117
ORF1ab/nsp12738D738YGacTac1515AY.260.000425
ORF1ab/nsp12738D738YGacTac1515P.1.140.000717
ORF1ab/nsp12738D738YGacTac1414AY.50.000289
ORF1ab/nsp12738D738YGacTac1414B.1.1.5190.000556
ORF1ab/nsp12738D738YGacTac1414B.1.2790.007191
ORF1ab/nsp12738D738YGacTac1111AY.470.000342
ORF1ab/nsp12738D738YGacTac1111B.1.5750.003337
ORF1ab/nsp12738D738YGacTac88AY.230.000558
ORF1ab/nsp12738D738YGacTac88C.370.000929
ORF1ab/nsp12738D738YGacTac77AY.850.00299
ORF1ab/nsp12738D738YGacTac77AY.90.000473
ORF1ab/nsp12738D738YGacTac77AY.9.20.000257
ORF1ab/nsp12738D738YGacTac77B.1.2210.000497
ORF1ab/nsp12738D738YGacTac66AY.200.000233
ORF1ab/nsp12738D738YGacTac66AY.300.002374
ORF1ab/nsp12738D738YGacTac66AY.460.000624
ORF1ab/nsp12738D738YGacTac66AY.60.000247
ORF1ab/nsp12738D738YGacTac66AY.99.20.000553
ORF1ab/nsp12738D738YGacTac66B.1.1.2140.000333
ORF1ab/nsp12738D738YGacTac66B.1.3510.000178
ORF1ab/nsp12738D738YGacTac66K.10.142857
ORF1ab/nsp12738D738YGacTac55AY.120.10.001605
ORF1ab/nsp12738D738YGacTac55AY.920.001436
ORF1ab/nsp12738D738YGacTac55B.1.5260.000118
ORF1ab/nsp12738D738YGacTac55B.1.617.10.000645
ORF1ab/nsp12738D738YGacTac44AY.1000.000184
ORF1ab/nsp12738D738YGacTac44AY.1170.000338
ORF1ab/nsp12738D738YGacTac44AY.39.10.000158
ORF1ab/nsp12738D738YGacTac44AY.5.30.00135
ORF1ab/nsp12738D738YGacTac44AY.740.000463
ORF1ab/nsp12738D738YGacTac44AY.840.00175
ORF1ab/nsp12738D738YGacTac44AY.98.10.000194
ORF1ab/nsp12738D738YGacTac44B.1.1.10.001307
ORF1ab/nsp12738D738YGacTac44B.1.1.120.029851
ORF1ab/nsp12738D738YGacTac44B.1.1.3060.001754
ORF1ab/nsp12738D738YGacTac44B.1.1.4320.005063
ORF1ab/nsp12738D738YGacTac44B.1.1600.000125
ORF1ab/nsp12738D738YGacTac44B.1.2430.000278
ORF1ab/nsp12738D738YGacTac44B.1.258.70.007648
ORF1ab/nsp12738D738YGacTac44P.1.170.000647
ORF1ab/nsp12738D738YGacTac33AY.1080.003308
ORF1ab/nsp12738D738YGacTac33AY.410.000882
ORF1ab/nsp12738D738YGacTac33AY.450.000365
ORF1ab/nsp12738D738YGacTac33AY.46.20.001906
ORF1ab/nsp12738D738YGacTac33AY.540.000286
ORF1ab/nsp12738D738YGacTac33AY.650.001599
ORF1ab/nsp12738D738YGacTac33AY.750.000168
ORF1ab/nsp12738D738YGacTac33AY.900.002053
ORF1ab/nsp12738D738YGacTac33B.1.1.1350.014085
ORF1ab/nsp12738D738YGacTac33B.1.1.1680.078947
ORF1ab/nsp12738D738YGacTac33B.1.177.350.002073
ORF1ab/nsp12738D738YGacTac33B.1.177.570.000843
ORF1ab/nsp12738D738YGacTac33B.1.2320.001612
ORF1ab/nsp12738D738YGacTac33B.1.3360.007317
ORF1ab/nsp12738D738YGacTac33B.1.36.290.001552
ORF1ab/nsp12738D738YGacTac33B.1.5250.000339
ORF1ab/nsp12738D738YGacTac33D.20.000225
ORF1ab/nsp12738D738YGacTac22A0.000774
ORF1ab/nsp12738D738YGacTac22AY.1130.000285
ORF1ab/nsp12738D738YGacTac22AY.1180.000125
ORF1ab/nsp12738D738YGacTac22AY.1210.000271
ORF1ab/nsp12738D738YGacTac22AY.160.000759
ORF1ab/nsp12738D738YGacTac22AY.75.10.000361
ORF1ab/nsp12738D738YGacTac22B.1.1.280.000622
ORF1ab/nsp12738D738YGacTac22B.1.1.3540.008772
ORF1ab/nsp12738D738YGacTac22B.1.1.3850.008929
ORF1ab/nsp12738D738YGacTac22B.1.177.600.000437
ORF1ab/nsp12738D738YGacTac22B.1.2400.000431
ORF1ab/nsp12738D738YGacTac22B.1.5950.000522
ORF1ab/nsp12738D738YGacTac11A.230.010526
ORF1ab/nsp12738D738YGacTac11AP.10.001502
ORF1ab/nsp12738D738YGacTac11AY.10.000396
ORF1ab/nsp12738D738YGacTac11AY.1070.000466
ORF1ab/nsp12738D738YGacTac11AY.1110.000183
ORF1ab/nsp12738D738YGacTac11AY.1160.000287
ORF1ab/nsp12738D738YGacTac11AY.120.000316
ORF1ab/nsp12738D738YGacTac11AY.130.000161
ORF1ab/nsp12738D738YGacTac11AY.16.10.00047
ORF1ab/nsp12738D738YGacTac11AY.280.00189
ORF1ab/nsp12738D738YGacTac11AY.29.10.000221
ORF1ab/nsp12738D738YGacTac11AY.3.10.000085
ORF1ab/nsp12738D738YGacTac11AY.350.000233
ORF1ab/nsp12738D738YGacTac11AY.39.1.10.000725
ORF1ab/nsp12738D738YGacTac11AY.4.2.10.000149
ORF1ab/nsp12738D738YGacTac11AY.4.40.000409
ORF1ab/nsp12738D738YGacTac11AY.420.00004
ORF1ab/nsp12738D738YGacTac11AY.46.60.000072
ORF1ab/nsp12738D738YGacTac11AY.5.40.000277
ORF1ab/nsp12738D738YGacTac11AY.520.000814
ORF1ab/nsp12738D738YGacTac11AY.570.000656
ORF1ab/nsp12738D738YGacTac11AY.590.00053
ORF1ab/nsp12738D738YGacTac11AY.610.000105
ORF1ab/nsp12738D738YGacTac11AY.680.000274
ORF1ab/nsp12738D738YGacTac11AY.690.000187
ORF1ab/nsp12738D738YGacTac11AY.7.10.000113
ORF1ab/nsp12738D738YGacTac11AY.9.10.000084
ORF1ab/nsp12738D738YGacTac11AY.940.000443
ORF1ab/nsp12738D738YGacTac11AY.960.002075
ORF1ab/nsp12738D738YGacTac11AY.980.000079
ORF1ab/nsp12738D738YGacTac11B.1.1.1010.01
ORF1ab/nsp12738D738YGacTac11B.1.1.1340.011364
ORF1ab/nsp12738D738YGacTac11B.1.1.1590.004673
ORF1ab/nsp12738D738YGacTac11B.1.1.1720.018182
ORF1ab/nsp12738D738YGacTac11B.1.1.2220.000204
ORF1ab/nsp12738D738YGacTac11B.1.1.2310.003096
ORF1ab/nsp12738D738YGacTac11B.1.1.2860.002899
ORF1ab/nsp12738D738YGacTac11B.1.1.2940.001266
ORF1ab/nsp12738D738YGacTac11B.1.1.3230.014085
ORF1ab/nsp12738D738YGacTac11B.1.1.390.00051
ORF1ab/nsp12738D738YGacTac11B.1.1.4480.002033
ORF1ab/nsp12738D738YGacTac11B.1.1.5220.017241
ORF1ab/nsp12738D738YGacTac11B.1.1110.001175
ORF1ab/nsp12738D738YGacTac11B.1.1690.014925
ORF1ab/nsp12738D738YGacTac11B.1.177.120.000152
ORF1ab/nsp12738D738YGacTac11B.1.177.230.003236
ORF1ab/nsp12738D738YGacTac11B.1.177.450.000381
ORF1ab/nsp12738D738YGacTac11B.1.177.580.001332
ORF1ab/nsp12738D738YGacTac11B.1.177.650.000665
ORF1ab/nsp12738D738YGacTac11B.1.177.830.001481
ORF1ab/nsp12738D738YGacTac11B.1.1890.004292
ORF1ab/nsp12738D738YGacTac11B.1.2580.000067
ORF1ab/nsp12738D738YGacTac11B.1.2930.0125
ORF1ab/nsp12738D738YGacTac11B.1.3110.000275
ORF1ab/nsp12738D738YGacTac11B.1.351.20.000303
ORF1ab/nsp12738D738YGacTac11B.1.360.000146
ORF1ab/nsp12738D738YGacTac11B.1.3610.001289
ORF1ab/nsp12738D738YGacTac11B.1.3750.00082
ORF1ab/nsp12738D738YGacTac11B.1.4000.000429
ORF1ab/nsp12738D738YGacTac11B.1.4020.009804
ORF1ab/nsp12738D738YGacTac11B.1.4090.000781
ORF1ab/nsp12738D738YGacTac11B.1.4280.00102
ORF1ab/nsp12738D738YGacTac11B.1.4370.020833
ORF1ab/nsp12738D738YGacTac11B.1.466.20.000391
ORF1ab/nsp12738D738YGacTac11B.1.4990.00105
ORF1ab/nsp12738D738YGacTac11B.1.575.10.002439
ORF1ab/nsp12738D738YGacTac11B.1.5770.000687
ORF1ab/nsp12738D738YGacTac11B.1.6210.000089
ORF1ab/nsp12738D738YGacTac11B.1.6270.00202
ORF1ab/nsp12738D738YGacTac11C.350.000774
ORF1ab/nsp12738D738YGacTac11C.360.000911
ORF1ab/nsp12738D738YGacTac11N.50.001767
ORF1ab/nsp12738D738YGacTac11P.1.80.004785
ORF1ab/nsp12738D738YGacTac11Q.10.000126
ORF1ab/nsp12738D738YGacTac11Q.30.000145
ORF1ab/nsp12738D738YGacTac11Q.80.000165
ORF1ab/nsp12738D738YGacTac11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.