CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = D738N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12738D738ND5130NnonsynGacAac80730.912515652-15654
ORF1ab/nsp12738D738ND5130NnonsynGaCAaT8070.087515652-15654

Details of the mutation D738N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12738D738NGacAac7380All0.000014
ORF1ab/nsp12738D738NGaCAaT780All0.000001
ORF1ab/nsp12738D738NGacAac1111AY.250.000066
ORF1ab/nsp12738D738NGacAac99B.1.1.5190.000357
ORF1ab/nsp12738D738NGacAac66B.1.1.70.000005
ORF1ab/nsp12738D738NGacAac55AY.40.000008
ORF1ab/nsp12738D738NGaCAaT55AY.560.008026
ORF1ab/nsp12738D738NGacAac55B.1.10.000091
ORF1ab/nsp12738D738NGacAac44AY.440.000024
ORF1ab/nsp12738D738NGacAac34B.1.617.20.000011
ORF1ab/nsp12738D738NGaCAaT14B.1.617.20.000004
ORF1ab/nsp12738D738NGacAac33AY.1030.000019
ORF1ab/nsp12738D738NGacAac33AY.750.000168
ORF1ab/nsp12738D738NGacAac33B.1.1770.00004
ORF1ab/nsp12738D738NGacAac220.111111
ORF1ab/nsp12738D738NGacAac22AY.330.000134
ORF1ab/nsp12738D738NGacAac22AY.420.00008
ORF1ab/nsp12738D738NGacAac22B.10.000018
ORF1ab/nsp12738D738NGacAac22B.1.177.170.001642
ORF1ab/nsp12738D738NGacAac22B.1.4700.002809
ORF1ab/nsp12738D738NGacAac11AY.1140.000231
ORF1ab/nsp12738D738NGaCAaT11AY.30.00001
ORF1ab/nsp12738D738NGacAac11AY.4.20.000022
ORF1ab/nsp12738D738NGacAac11AY.4.50.000107
ORF1ab/nsp12738D738NGacAac11AY.46.60.000072
ORF1ab/nsp12738D738NGacAac11AY.98.10.000048
ORF1ab/nsp12738D738NGacAac11B.1.1.700.000341
ORF1ab/nsp12738D738NGacAac11B.1.20.000009
ORF1ab/nsp12738D738NGacAac11B.1.2390.001221
ORF1ab/nsp12738D738NGacAac11B.1.2400.000216

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.