CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = D269N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12269D269ND4661NnonsynGatAat14561456114245-14247

Details of the mutation D269N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12269D269NGatAat14561456All0.000278
ORF1ab/nsp12269D269NGatAat10111011B.1.1.70.000905
ORF1ab/nsp12269D269NGatAat218218B.1.6180.879032
ORF1ab/nsp12269D269NGatAat7777AY.40.00012
ORF1ab/nsp12269D269NGatAat3030B.1.617.20.000113
ORF1ab/nsp12269D269NGatAat1919B.10.000174
ORF1ab/nsp12269D269NGatAat1515B.1.5820.00736
ORF1ab/nsp12269D269NGatAat99AY.250.000054
ORF1ab/nsp12269D269NGatAat99AY.440.000055
ORF1ab/nsp12269D269NGatAat88AY.430.000035
ORF1ab/nsp12269D269NGatAat66AY.260.00017
ORF1ab/nsp12269D269NGatAat55AY.1030.000031
ORF1ab/nsp12269D269NGatAat55AY.30.00005
ORF1ab/nsp12269D269NGatAat44B.1.10.000073
ORF1ab/nsp12269D269NGatAat33B.1.1.2160.002671
ORF1ab/nsp12269D269NGatAat22AY.130.000322
ORF1ab/nsp12269D269NGatAat22AY.390.000049
ORF1ab/nsp12269D269NGatAat22AY.99.20.000184
ORF1ab/nsp12269D269NGatAat22B.1.20.000018
ORF1ab/nsp12269D269NGatAat22B.1.2210.000142
ORF1ab/nsp12269D269NGatAat22Q.80.00033
ORF1ab/nsp12269D269NGatAat110.055556
ORF1ab/nsp12269D269NGatAat11AH.20.012048
ORF1ab/nsp12269D269NGatAat11AY.1140.000231
ORF1ab/nsp12269D269NGatAat11AY.1180.000063
ORF1ab/nsp12269D269NGatAat11AY.230.00007
ORF1ab/nsp12269D269NGatAat11AY.290.000016
ORF1ab/nsp12269D269NGatAat11AY.300.000396
ORF1ab/nsp12269D269NGatAat11AY.330.000067
ORF1ab/nsp12269D269NGatAat11AY.380.000499
ORF1ab/nsp12269D269NGatAat11AY.460.000104
ORF1ab/nsp12269D269NGatAat11AY.46.10.001027
ORF1ab/nsp12269D269NGatAat11AY.46.60.000072
ORF1ab/nsp12269D269NGatAat11AY.720.001361
ORF1ab/nsp12269D269NGatAat11AY.730.000665
ORF1ab/nsp12269D269NGatAat11AY.98.10.000048
ORF1ab/nsp12269D269NGatAat11B.1.1.1610.003534
ORF1ab/nsp12269D269NGatAat11B.1.1.2140.000055
ORF1ab/nsp12269D269NGatAat11B.1.1.3480.000796
ORF1ab/nsp12269D269NGatAat11B.1.1600.000031
ORF1ab/nsp12269D269NGatAat11B.1.1770.000013
ORF1ab/nsp12269D269NGatAat11B.1.2580.000067
ORF1ab/nsp12269D269NGatAat11B.1.3910.001127
ORF1ab/nsp12269D269NGatAat11B.1.5960.000087
ORF1ab/nsp12269D269NGatAat11P.10.000016
ORF1ab/nsp12269D269NGatAat11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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