CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = A382A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12382A382AA4774AsyngcTgcC4462750.61659214584-14586
ORF1ab/nsp12382A382AA4774AsyngcTgcA4461550.34753414584-14586
ORF1ab/nsp12382A382AA4774AsyngcTgcG446160.035874414584-14586

Details of the mutation A382A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12382A382AgcTgcC275446All0.000053
ORF1ab/nsp12382A382AgcTgcA155446All0.00003
ORF1ab/nsp12382A382AgcTgcG16446All0.000003
ORF1ab/nsp12382A382AgcTgcC133183B.1.1.70.000119
ORF1ab/nsp12382A382AgcTgcA50183B.1.1.70.000045
ORF1ab/nsp12382A382AgcTgcC1825AY.40.000028
ORF1ab/nsp12382A382AgcTgcA725AY.40.000011
ORF1ab/nsp12382A382AgcTgcA1121B.1.617.20.000041
ORF1ab/nsp12382A382AgcTgcC1021B.1.617.20.000038
ORF1ab/nsp12382A382AgcTgcG1415B.1.2210.000994
ORF1ab/nsp12382A382AgcTgcC115B.1.2210.000071
ORF1ab/nsp12382A382AgcTgcA1314AY.1030.000081
ORF1ab/nsp12382A382AgcTgcC114AY.1030.000006
ORF1ab/nsp12382A382AgcTgcA812AY.250.000048
ORF1ab/nsp12382A382AgcTgcC412AY.250.000024
ORF1ab/nsp12382A382AgcTgcA1212B.1.1770.000158
ORF1ab/nsp12382A382AgcTgcC1111B.1.1.3170.004529
ORF1ab/nsp12382A382AgcTgcC910B.1.1.5190.000357
ORF1ab/nsp12382A382AgcTgcA110B.1.1.5190.00004
ORF1ab/nsp12382A382AgcTgcA910B.1.4290.000212
ORF1ab/nsp12382A382AgcTgcC110B.1.4290.000024
ORF1ab/nsp12382A382AgcTgcA59B.1.20.000044
ORF1ab/nsp12382A382AgcTgcC49B.1.20.000035
ORF1ab/nsp12382A382AgcTgcC89B.1.5250.000905
ORF1ab/nsp12382A382AgcTgcG19B.1.5250.000113
ORF1ab/nsp12382A382AgcTgcC67AY.30.00006
ORF1ab/nsp12382A382AgcTgcA17AY.30.00001
ORF1ab/nsp12382A382AgcTgcA66AY.1140.001387
ORF1ab/nsp12382A382AgcTgcC55AY.1020.000133
ORF1ab/nsp12382A382AgcTgcC55AY.390.000124
ORF1ab/nsp12382A382AgcTgcC45AY.440.000024
ORF1ab/nsp12382A382AgcTgcA15AY.440.000006
ORF1ab/nsp12382A382AgcTgcC55AY.610.000524
ORF1ab/nsp12382A382AgcTgcC45B.10.000037
ORF1ab/nsp12382A382AgcTgcA15B.10.000009
ORF1ab/nsp12382A382AgcTgcC35B.1.3510.000089
ORF1ab/nsp12382A382AgcTgcA25B.1.3510.000059
ORF1ab/nsp12382A382AgcTgcC45P.10.000063
ORF1ab/nsp12382A382AgcTgcA15P.10.000016
ORF1ab/nsp12382A382AgcTgcC24B.1.10.000036
ORF1ab/nsp12382A382AgcTgcA24B.1.10.000036
ORF1ab/nsp12382A382AgcTgcA34B.1.1.2220.000612
ORF1ab/nsp12382A382AgcTgcC14B.1.1.2220.000204
ORF1ab/nsp12382A382AgcTgcC44B.1.360.000584
ORF1ab/nsp12382A382AgcTgcA23P.1.140.000096
ORF1ab/nsp12382A382AgcTgcG13P.1.140.000048
ORF1ab/nsp12382A382AgcTgcC22AY.1160.000574
ORF1ab/nsp12382A382AgcTgcC22AY.116.10.000623
ORF1ab/nsp12382A382AgcTgcA22AY.1190.000071
ORF1ab/nsp12382A382AgcTgcA22AY.20.000712
ORF1ab/nsp12382A382AgcTgcC12AY.430.000004
ORF1ab/nsp12382A382AgcTgcA12AY.430.000004
ORF1ab/nsp12382A382AgcTgcC22AY.46.40.000329
ORF1ab/nsp12382A382AgcTgcC22AY.50.000041
ORF1ab/nsp12382A382AgcTgcC22AY.500.001599
ORF1ab/nsp12382A382AgcTgcA22AY.510.001818
ORF1ab/nsp12382A382AgcTgcA22AY.540.000191
ORF1ab/nsp12382A382AgcTgcC22AY.700.000417
ORF1ab/nsp12382A382AgcTgcC22AY.840.000875
ORF1ab/nsp12382A382AgcTgcC22B.1.1110.00235
ORF1ab/nsp12382A382AgcTgcA12B.1.4270.00005
ORF1ab/nsp12382A382AgcTgcC12B.1.4270.00005
ORF1ab/nsp12382A382AgcTgcC11AD.20.000219
ORF1ab/nsp12382A382AgcTgcC11AY.1210.000135
ORF1ab/nsp12382A382AgcTgcC11AY.160.00038
ORF1ab/nsp12382A382AgcTgcC11AY.200.000039
ORF1ab/nsp12382A382AgcTgcA11AY.350.000233
ORF1ab/nsp12382A382AgcTgcA11AY.470.000031
ORF1ab/nsp12382A382AgcTgcA11AY.60.000041
ORF1ab/nsp12382A382AgcTgcC11B0.000128
ORF1ab/nsp12382A382AgcTgcC11B.1.1.3340.016393
ORF1ab/nsp12382A382AgcTgcC11B.1.1.410.006329
ORF1ab/nsp12382A382AgcTgcC11B.1.1.4480.002033
ORF1ab/nsp12382A382AgcTgcA11B.1.177.60.000977
ORF1ab/nsp12382A382AgcTgcA11B.1.2580.000067
ORF1ab/nsp12382A382AgcTgcC11B.1.2680.010417
ORF1ab/nsp12382A382AgcTgcC11B.1.3360.002439
ORF1ab/nsp12382A382AgcTgcA11B.1.3600.012658
ORF1ab/nsp12382A382AgcTgcC11B.1.4530.003236
ORF1ab/nsp12382A382AgcTgcA11B.1.466.20.000391
ORF1ab/nsp12382A382AgcTgcC11B.1.5510.00129
ORF1ab/nsp12382A382AgcTgcA11B.1.5760.000907
ORF1ab/nsp12382A382AgcTgcA11B.1.6000.005848
ORF1ab/nsp12382A382AgcTgcC11B.1.6360.006711
ORF1ab/nsp12382A382AgcTgcA11Q.40.000455
ORF1ab/nsp12382A382AgcTgcC11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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