CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : Mut = A253A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12253A253AA4645AsyngcAgcG5284570.8655314197-14199
ORF1ab/nsp12253A253AA4645AsyngcAgcT528570.10795514197-14199
ORF1ab/nsp12253A253AA4645AsyngcAgcC528140.026515214197-14199

Details of the mutation A253A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12253A253AgcAgcG457528All0.000087
ORF1ab/nsp12253A253AgcAgcT57528All0.000011
ORF1ab/nsp12253A253AgcAgcC14528All0.000003
ORF1ab/nsp12253A253AgcAgcG133144B.1.1.70.000119
ORF1ab/nsp12253A253AgcAgcT7144B.1.1.70.000006
ORF1ab/nsp12253A253AgcAgcC4144B.1.1.70.000004
ORF1ab/nsp12253A253AgcAgcG127130B.1.20.001118
ORF1ab/nsp12253A253AgcAgcC2130B.1.20.000018
ORF1ab/nsp12253A253AgcAgcT1130B.1.20.000009
ORF1ab/nsp12253A253AgcAgcG4848B.1.1.4320.060759
ORF1ab/nsp12253A253AgcAgcG2531B.10.000229
ORF1ab/nsp12253A253AgcAgcT531B.10.000046
ORF1ab/nsp12253A253AgcAgcC131B.10.000009
ORF1ab/nsp12253A253AgcAgcG1323AY.30.000129
ORF1ab/nsp12253A253AgcAgcT1023AY.30.000099
ORF1ab/nsp12253A253AgcAgcG1515B.1.360.002189
ORF1ab/nsp12253A253AgcAgcG1414B.1.5820.006869
ORF1ab/nsp12253A253AgcAgcT913AY.40.000014
ORF1ab/nsp12253A253AgcAgcG413AY.40.000006
ORF1ab/nsp12253A253AgcAgcG1011B.1.617.20.000038
ORF1ab/nsp12253A253AgcAgcT111B.1.617.20.000004
ORF1ab/nsp12253A253AgcAgcG77B.1.1770.000092
ORF1ab/nsp12253A253AgcAgcT77B.1.350.11
ORF1ab/nsp12253A253AgcAgcG36AY.440.000018
ORF1ab/nsp12253A253AgcAgcC26AY.440.000012
ORF1ab/nsp12253A253AgcAgcT16AY.440.000006
ORF1ab/nsp12253A253AgcAgcG36P.10.000047
ORF1ab/nsp12253A253AgcAgcT36P.10.000047
ORF1ab/nsp12253A253AgcAgcT35AY.250.000018
ORF1ab/nsp12253A253AgcAgcC25AY.250.000012
ORF1ab/nsp12253A253AgcAgcG55AY.300.001979
ORF1ab/nsp12253A253AgcAgcG44B.1.160.170.006803
ORF1ab/nsp12253A253AgcAgcG33A.10.000846
ORF1ab/nsp12253A253AgcAgcG33AY.1030.000019
ORF1ab/nsp12253A253AgcAgcT33B.1.1.5190.000119
ORF1ab/nsp12253A253AgcAgcG33B.1.3370.01676
ORF1ab/nsp12253A253AgcAgcG22AY.1000.000092
ORF1ab/nsp12253A253AgcAgcT12AY.1190.000035
ORF1ab/nsp12253A253AgcAgcG12AY.1190.000035
ORF1ab/nsp12253A253AgcAgcG22AY.230.000139
ORF1ab/nsp12253A253AgcAgcG22AY.450.000243
ORF1ab/nsp12253A253AgcAgcG22B.1.1600.000062
ORF1ab/nsp12253A253AgcAgcT22B.1.2210.000142
ORF1ab/nsp12253A253AgcAgcG22B.1.4290.000047
ORF1ab/nsp12253A253AgcAgcG110.055556
ORF1ab/nsp12253A253AgcAgcG11AY.1020.000027
ORF1ab/nsp12253A253AgcAgcG11AY.1060.000335
ORF1ab/nsp12253A253AgcAgcG11AY.1200.000037
ORF1ab/nsp12253A253AgcAgcC11AY.140.000088
ORF1ab/nsp12253A253AgcAgcG11AY.380.000499
ORF1ab/nsp12253A253AgcAgcG11AY.390.000025
ORF1ab/nsp12253A253AgcAgcG11AY.39.10.00004
ORF1ab/nsp12253A253AgcAgcG11AY.430.000004
ORF1ab/nsp12253A253AgcAgcG11AY.46.40.000165
ORF1ab/nsp12253A253AgcAgcC11AY.470.000031
ORF1ab/nsp12253A253AgcAgcT11AY.590.00053
ORF1ab/nsp12253A253AgcAgcT11AY.740.000116
ORF1ab/nsp12253A253AgcAgcC11AY.850.000427
ORF1ab/nsp12253A253AgcAgcG11AY.9.20.000037
ORF1ab/nsp12253A253AgcAgcG11B.1.10.000018
ORF1ab/nsp12253A253AgcAgcG11B.1.1.2070.001182
ORF1ab/nsp12253A253AgcAgcG11B.1.1.2140.000055
ORF1ab/nsp12253A253AgcAgcG11B.1.1.3150.008475
ORF1ab/nsp12253A253AgcAgcG11B.1.1.3350.012987
ORF1ab/nsp12253A253AgcAgcT11B.1.1.370.000193
ORF1ab/nsp12253A253AgcAgcG11B.1.1.3750.011905
ORF1ab/nsp12253A253AgcAgcG11B.1.160.160.000929
ORF1ab/nsp12253A253AgcAgcG11B.1.2580.000067
ORF1ab/nsp12253A253AgcAgcG11B.1.3500.002933
ORF1ab/nsp12253A253AgcAgcG11B.1.3510.00003
ORF1ab/nsp12253A253AgcAgcT11B.1.4590.004082
ORF1ab/nsp12253A253AgcAgcG11B.1.4740.001901
ORF1ab/nsp12253A253AgcAgcG11B.1.5260.000024
ORF1ab/nsp12253A253AgcAgcG11B.1.5770.000687
ORF1ab/nsp12253A253AgcAgcG11B.6.60.000889
ORF1ab/nsp12253A253AgcAgcG11P.1.140.000048
ORF1ab/nsp12253A253AgcAgcG11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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