CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 846

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12846D846DD5238DsyngaTgaC18611861115976-15978
ORF1ab/nsp12846D846GD5238GnonsyngAtgGt245245115976-15978
ORF1ab/nsp12846D846YD5238YnonsynGatTat5151115976-15978
ORF1ab/nsp12846D846delD5238deldelGAT---4444115976-15978
ORF1ab/nsp12846D846AD5238AnonsyngAtgCt3939115976-15978
ORF1ab/nsp12846D846ND5238NnonsynGatAat3434115976-15978
ORF1ab/nsp12846D846ED5238EnonsyngaTgaG20190.9515976-15978
ORF1ab/nsp12846D846ED5238EnonsyngaTgaA2010.0515976-15978
ORF1ab/nsp12846D846HD5238HnonsynGatCat88115976-15978
ORF1ab/nsp12846D846del2D5238del2delgATg--88115976-15978
ORF1ab/nsp12846D846del1D5238del1delGat-at320.66666715976-15978
ORF1ab/nsp12846D846del1D5238del1delgaTga-310.33333315976-15978
ORF1ab/nsp12846D846VD5238VnonsyngAtgTt22115976-15978

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12846D846DgaTgaC18611861All0.000356
ORF1ab/nsp12846D846DgaTgaC947947B.1.1600.029535
ORF1ab/nsp12846D846GgAtgGt245245All0.000047
ORF1ab/nsp12846D846GgAtgGt216216AY.250.001299
ORF1ab/nsp12846D846DgaTgaC156156AY.40.000243
ORF1ab/nsp12846D846DgaTgaC8080B.1.5960.006971
ORF1ab/nsp12846D846DgaTgaC7474B.1.1.70.000066
ORF1ab/nsp12846D846DgaTgaC6161B.1.617.20.00023
ORF1ab/nsp12846D846DgaTgaC5959AY.1030.000366
ORF1ab/nsp12846D846DgaTgaC5555B.1.10.000998
ORF1ab/nsp12846D846YGatTat5151All0.00001
ORF1ab/nsp12846D846DgaTgaC4545B.1.20.000396
ORF1ab/nsp12846D846delGAT---4444All0.000008
ORF1ab/nsp12846D846AgAtgCt3939All0.000007
ORF1ab/nsp12846D846NGatAat3434All0.000007
ORF1ab/nsp12846D846DgaTgaC2727AY.430.00012
ORF1ab/nsp12846D846DgaTgaC2626B.1.1770.000342
ORF1ab/nsp12846D846DgaTgaC2525AY.410.007349
ORF1ab/nsp12846D846DgaTgaC2323AY.260.000651
ORF1ab/nsp12846D846DgaTgaC2222AY.50.000454
ORF1ab/nsp12846D846DgaTgaC2222B.1.5260.000517
ORF1ab/nsp12846D846EgaTgaG1920All0.000004
ORF1ab/nsp12846D846EgaTgaA120All0
ORF1ab/nsp12846D846DgaTgaC1919AY.1000.000874
ORF1ab/nsp12846D846DgaTgaC1919B.10.000174
ORF1ab/nsp12846D846GgAtgGt1818AY.40.000028
ORF1ab/nsp12846D846DgaTgaC1515AY.250.00009
ORF1ab/nsp12846D846DgaTgaC1515AY.30.000149
ORF1ab/nsp12846D846DgaTgaC1515AY.440.000091
ORF1ab/nsp12846D846delGAT---1515B.1.1.70.000013
ORF1ab/nsp12846D846DgaTgaC1414AY.4.20.000304
ORF1ab/nsp12846D846EgaTgaG1313B.1.1.70.000012
ORF1ab/nsp12846D846YGatTat1212AY.40.000019
ORF1ab/nsp12846D846AgAtgCt1111B.1.5310.916667
ORF1ab/nsp12846D846DgaTgaC1010B.1.1.5190.000397
ORF1ab/nsp12846D846DgaTgaC99AY.470.00028
ORF1ab/nsp12846D846DgaTgaC99P.10.000142
ORF1ab/nsp12846D846del2gATg--88All0.000002
ORF1ab/nsp12846D846HGatCat88All0.000002
ORF1ab/nsp12846D846DgaTgaC88B.1.2580.000532
ORF1ab/nsp12846D846DgaTgaC77AY.390.000173
ORF1ab/nsp12846D846DgaTgaC77B.1.2400.001509
ORF1ab/nsp12846D846AgAtgCt66AY.40.000009
ORF1ab/nsp12846D846NGatAat66AY.40.000009
ORF1ab/nsp12846D846YGatTat66B.1.1.70.000005
ORF1ab/nsp12846D846NGatAat66B.1.617.20.000023
ORF1ab/nsp12846D846DgaTgaC55AY.350.001165
ORF1ab/nsp12846D846DgaTgaC55B.1.177.600.001092
ORF1ab/nsp12846D846DgaTgaC55B.1.36.290.002587
ORF1ab/nsp12846D846GgAtgGt55B.1.617.20.000019
ORF1ab/nsp12846D846AgAtgCt44AY.1030.000025
ORF1ab/nsp12846D846DgaTgaC44AY.230.000279
ORF1ab/nsp12846D846DgaTgaC44AY.340.000388
ORF1ab/nsp12846D846DgaTgaC44B.1.2430.000278
ORF1ab/nsp12846D846del1Gat-at23All0
ORF1ab/nsp12846D846del1gaTga-13All0
ORF1ab/nsp12846D846NGatAat33AY.1030.000019
ORF1ab/nsp12846D846NGatAat33AY.430.000013
ORF1ab/nsp12846D846DgaTgaC33AY.850.001282
ORF1ab/nsp12846D846YGatTat33AY.98.10.000145
ORF1ab/nsp12846D846YGatTat33B.1.1.5190.000119
ORF1ab/nsp12846D846AgAtgCt33B.1.1.70.000003
ORF1ab/nsp12846D846delGAT---33B.1.1.700.001023
ORF1ab/nsp12846D846delGAT---33B.1.1770.00004
ORF1ab/nsp12846D846DgaTgaC33B.1.177.320.004049
ORF1ab/nsp12846D846NGatAat33B.1.20.000026
ORF1ab/nsp12846D846DgaTgaC33B.1.3490.002144
ORF1ab/nsp12846D846AgAtgCt33B.1.617.20.000011
ORF1ab/nsp12846D846DgaTgaC33R.10.00027
ORF1ab/nsp12846D846YGatTat33R.10.00027
ORF1ab/nsp12846D846VgAtgTt22All0
ORF1ab/nsp12846D846DgaTgaC22AY.1100.000225
ORF1ab/nsp12846D846DgaTgaC22AY.1170.000169
ORF1ab/nsp12846D846DgaTgaC22AY.1190.000071
ORF1ab/nsp12846D846GgAtgGt22AY.290.000032
ORF1ab/nsp12846D846DgaTgaC22AY.330.000134
ORF1ab/nsp12846D846delGAT---22AY.40.000003
ORF1ab/nsp12846D846NGatAat22AY.4.20.000043
ORF1ab/nsp12846D846delGAT---22AY.430.000009
ORF1ab/nsp12846D846YGatTat22AY.430.000009
ORF1ab/nsp12846D846YGatTat22AY.440.000012
ORF1ab/nsp12846D846NGatAat22AY.440.000012
ORF1ab/nsp12846D846GgAtgGt22AY.440.000012
ORF1ab/nsp12846D846HGatCat22AY.610.00021
ORF1ab/nsp12846D846YGatTat22B.10.000018
ORF1ab/nsp12846D846delGAT---22B.1.10.000036
ORF1ab/nsp12846D846YGatTat22B.1.10.000036
ORF1ab/nsp12846D846DgaTgaC22B.1.1.3060.000877
ORF1ab/nsp12846D846NGatAat22B.1.1.3260.003521
ORF1ab/nsp12846D846del2gATg--22B.1.1.70.000002
ORF1ab/nsp12846D846DgaTgaC22B.1.160.290.008439
ORF1ab/nsp12846D846delGAT---22B.1.177.540.001213
ORF1ab/nsp12846D846AgAtgCt22B.1.20.000018
ORF1ab/nsp12846D846del2gATg--22B.1.20.000018
ORF1ab/nsp12846D846DgaTgaC22B.1.2310.064516
ORF1ab/nsp12846D846EgaTgaG22B.1.2430.000139
ORF1ab/nsp12846D846DgaTgaC22B.1.351.20.000605
ORF1ab/nsp12846D846NGatAat22B.1.5960.000174
ORF1ab/nsp12846D846delGAT---22B.1.617.20.000008
ORF1ab/nsp12846D846DgaTgaC22D.20.00015
ORF1ab/nsp12846D846DgaTgaC22Q.10.000253
ORF1ab/nsp12846D846YGatTat11A0.000387
ORF1ab/nsp12846D846AgAtgCt11A.270.001656
ORF1ab/nsp12846D846HGatCat11AY.1030.000006
ORF1ab/nsp12846D846DgaTgaC11AY.1060.000335
ORF1ab/nsp12846D846delGAT---11AY.1110.000183
ORF1ab/nsp12846D846AgAtgCt11AY.1180.000063
ORF1ab/nsp12846D846delGAT---11AY.1200.000037
ORF1ab/nsp12846D846DgaTgaC11AY.120.10.000321
ORF1ab/nsp12846D846NGatAat11AY.120.10.000321
ORF1ab/nsp12846D846del2gATg--11AY.120.2.10.000498
ORF1ab/nsp12846D846DgaTgaC11AY.160.00038
ORF1ab/nsp12846D846AgAtgCt11AY.16.10.00047
ORF1ab/nsp12846D846delGAT---11AY.250.000006
ORF1ab/nsp12846D846DgaTgaC11AY.270.000065
ORF1ab/nsp12846D846DgaTgaC11AY.290.000016
ORF1ab/nsp12846D846YGatTat11AY.290.000016
ORF1ab/nsp12846D846NGatAat11AY.30.00001
ORF1ab/nsp12846D846YGatTat11AY.30.00001
ORF1ab/nsp12846D846EgaTgaA11AY.390.000025
ORF1ab/nsp12846D846HGatCat11AY.40.000002
ORF1ab/nsp12846D846EgaTgaG11AY.40.000002
ORF1ab/nsp12846D846delGAT---11AY.4.50.000107
ORF1ab/nsp12846D846DgaTgaC11AY.420.00004
ORF1ab/nsp12846D846EgaTgaG11AY.430.000004
ORF1ab/nsp12846D846AgAtgCt11AY.440.000006
ORF1ab/nsp12846D846DgaTgaC11AY.450.000122
ORF1ab/nsp12846D846del2gATg--11AY.460.000104
ORF1ab/nsp12846D846AgAtgCt11AY.46.40.000165
ORF1ab/nsp12846D846HGatCat11AY.480.000465
ORF1ab/nsp12846D846YGatTat11AY.50.000021
ORF1ab/nsp12846D846DgaTgaC11AY.510.000909
ORF1ab/nsp12846D846DgaTgaC11AY.60.000041
ORF1ab/nsp12846D846DgaTgaC11AY.690.000187
ORF1ab/nsp12846D846DgaTgaC11AY.7.10.000113
ORF1ab/nsp12846D846del2gATg--11AY.750.000056
ORF1ab/nsp12846D846DgaTgaC11AY.930.000273
ORF1ab/nsp12846D846AgAtgCt11AY.980.000079
ORF1ab/nsp12846D846NGatAat11AY.98.10.000048
ORF1ab/nsp12846D846DgaTgaC11AY.99.20.000092
ORF1ab/nsp12846D846delGAT---11B0.000128
ORF1ab/nsp12846D846DgaTgaC11B0.000128
ORF1ab/nsp12846D846YGatTat11B0.000128
ORF1ab/nsp12846D846AgAtgCt11B.10.000009
ORF1ab/nsp12846D846GgAtgGt11B.10.000009
ORF1ab/nsp12846D846EgaTgaG11B.1.10.000018
ORF1ab/nsp12846D846YGatTat11B.1.1.1280.007092
ORF1ab/nsp12846D846DgaTgaC11B.1.1.2140.000055
ORF1ab/nsp12846D846DgaTgaC11B.1.1.2220.000204
ORF1ab/nsp12846D846delGAT---11B.1.1.3110.000358
ORF1ab/nsp12846D846DgaTgaC11B.1.1.3620.005618
ORF1ab/nsp12846D846HGatCat11B.1.1.460.004367
ORF1ab/nsp12846D846NGatAat11B.1.1.5190.00004
ORF1ab/nsp12846D846VgAtgTt11B.1.1.70.000001
ORF1ab/nsp12846D846DgaTgaC11B.1.1.700.000341
ORF1ab/nsp12846D846DgaTgaC11B.1.1.950.019608
ORF1ab/nsp12846D846DgaTgaC11B.1.160.150.00495
ORF1ab/nsp12846D846DgaTgaC11B.1.160.210.020408
ORF1ab/nsp12846D846YGatTat11B.1.1770.000013
ORF1ab/nsp12846D846NGatAat11B.1.1770.000013
ORF1ab/nsp12846D846delGAT---11B.1.177.210.000076
ORF1ab/nsp12846D846delGAT---11B.1.177.40.000211
ORF1ab/nsp12846D846delGAT---11B.1.177.510.004566
ORF1ab/nsp12846D846YGatTat11B.1.177.550.002331
ORF1ab/nsp12846D846delGAT---11B.1.177.560.000668
ORF1ab/nsp12846D846delGAT---11B.1.177.690.001484
ORF1ab/nsp12846D846delGAT---11B.1.177.830.001481
ORF1ab/nsp12846D846DgaTgaC11B.1.177.860.000183
ORF1ab/nsp12846D846GgAtgGt11B.1.20.000009
ORF1ab/nsp12846D846del1gaTga-11B.1.20.000009
ORF1ab/nsp12846D846YGatTat11B.1.2340.000132
ORF1ab/nsp12846D846DgaTgaC11B.1.2340.000132
ORF1ab/nsp12846D846VgAtgTt11B.1.2600.003344
ORF1ab/nsp12846D846AgAtgCt11B.1.3110.000275
ORF1ab/nsp12846D846YGatTat11B.1.3510.00003
ORF1ab/nsp12846D846DgaTgaC11B.1.360.000146
ORF1ab/nsp12846D846YGatTat11B.1.360.000146
ORF1ab/nsp12846D846del1Gat-at11B.1.36.80.001
ORF1ab/nsp12846D846DgaTgaC11B.1.3960.000706
ORF1ab/nsp12846D846DgaTgaC11B.1.4270.00005
ORF1ab/nsp12846D846AgAtgCt11B.1.4280.00102
ORF1ab/nsp12846D846DgaTgaC11B.1.4290.000024
ORF1ab/nsp12846D846YGatTat11B.1.4290.000024
ORF1ab/nsp12846D846AgAtgCt11B.1.4290.000024
ORF1ab/nsp12846D846HGatCat11B.1.5440.006024
ORF1ab/nsp12846D846DgaTgaC11B.1.5550.022222
ORF1ab/nsp12846D846EgaTgaG11B.1.5760.000907
ORF1ab/nsp12846D846del2gATg--11B.1.5760.000907
ORF1ab/nsp12846D846DgaTgaC11B.1.6000.005848
ORF1ab/nsp12846D846YGatTat11B.1.617.20.000004
ORF1ab/nsp12846D846DgaTgaC11B.1.6370.000073
ORF1ab/nsp12846D846YGatTat11B.30.000831
ORF1ab/nsp12846D846delGAT---11B.550.00295
ORF1ab/nsp12846D846DgaTgaC11C.370.000116
ORF1ab/nsp12846D846YGatTat11D.20.000075
ORF1ab/nsp12846D846HGatCat11D.20.000075
ORF1ab/nsp12846D846del1Gat-at11D.20.000075
ORF1ab/nsp12846D846DgaTgaC11P.1.140.000048
ORF1ab/nsp12846D846YGatTat11Q.70.001111
ORF1ab/nsp12846D846DgaTgaC11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.