CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 742

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12742V742VV5134VsyngtGgtT4172990.71702615664-15666
ORF1ab/nsp12742V742VV5134VsyngtGgtA417990.2374115664-15666
ORF1ab/nsp12742V742VV5134VsyngtGgtC417190.045563515664-15666
ORF1ab/nsp12742V742LV5134LnonsynGtgTtg3723670.98655915664-15666
ORF1ab/nsp12742V742LV5134LnonsynGtgCtg37250.013440915664-15666
ORF1ab/nsp12742V742AV5134AnonsyngTggCg130130115664-15666
ORF1ab/nsp12742V742MV5134MnonsynGtgAtg6666115664-15666
ORF1ab/nsp12742V742delV5134deldelGTG---1515115664-15666
ORF1ab/nsp12742V742GV5134GnonsyngTggGg1090.915664-15666
ORF1ab/nsp12742V742GV5134GnonsyngTGgGA1010.115664-15666
ORF1ab/nsp12742V742EV5134EnonsyngTggAg66115664-15666
ORF1ab/nsp12742V742KV5134KnonsynGTgAAg430.7515664-15666
ORF1ab/nsp12742V742del1V5134del1delGtg-tg430.7515664-15666
ORF1ab/nsp12742V742del1V5134del1delGTgA-g410.2515664-15666
ORF1ab/nsp12742V742KV5134KnonsynGTGAAA410.2515664-15666
ORF1ab/nsp12742V742RV5134RnonsynGTgAGg22115664-15666
ORF1ab/nsp12742V742del2V5134del2delGTG--C11115664-15666
ORF1ab/nsp12742V742XV5134XnonsynGTGTAA11115664-15666

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12742V742VgtGgtT299417All0.000057
ORF1ab/nsp12742V742VgtGgtA99417All0.000019
ORF1ab/nsp12742V742VgtGgtC19417All0.000004
ORF1ab/nsp12742V742LGtgTtg367372All0.00007
ORF1ab/nsp12742V742LGtgCtg5372All0.000001
ORF1ab/nsp12742V742VgtGgtT137140B.1.1.70.000123
ORF1ab/nsp12742V742VgtGgtC2140B.1.1.70.000002
ORF1ab/nsp12742V742VgtGgtA1140B.1.1.70.000001
ORF1ab/nsp12742V742LGtgTtg138138AY.140.012146
ORF1ab/nsp12742V742AgTggCg130130All0.000025
ORF1ab/nsp12742V742MGtgAtg6666All0.000013
ORF1ab/nsp12742V742VgtGgtT6666AY.39.10.002614
ORF1ab/nsp12742V742AgTggCg6464B.1.5260.001504
ORF1ab/nsp12742V742LGtgTtg4244B.1.1.70.000038
ORF1ab/nsp12742V742LGtgCtg244B.1.1.70.000002
ORF1ab/nsp12742V742VgtGgtT2633AY.40.00004
ORF1ab/nsp12742V742VgtGgtA533AY.40.000008
ORF1ab/nsp12742V742VgtGgtC233AY.40.000003
ORF1ab/nsp12742V742LGtgTtg3030B.1.617.20.000113
ORF1ab/nsp12742V742LGtgTtg2222AY.440.000134
ORF1ab/nsp12742V742MGtgAtg1818AY.40.000028
ORF1ab/nsp12742V742VgtGgtA1717B.1.4090.013281
ORF1ab/nsp12742V742LGtgTtg1616AY.40.000025
ORF1ab/nsp12742V742VgtGgtA1616B.1.1.3301
ORF1ab/nsp12742V742delGTG---1515All0.000003
ORF1ab/nsp12742V742VgtGgtT1415AY.430.000062
ORF1ab/nsp12742V742VgtGgtA115AY.430.000004
ORF1ab/nsp12742V742AgTggCg1212AY.40.000019
ORF1ab/nsp12742V742AgTggCg1111AY.1160.003155
ORF1ab/nsp12742V742LGtgTtg1111B.1.1600.000343
ORF1ab/nsp12742V742GgTggGg910All0.000002
ORF1ab/nsp12742V742GgTGgGA110All0
ORF1ab/nsp12742V742LGtgTtg1010AY.260.000283
ORF1ab/nsp12742V742VgtGgtC710B.1.1770.000092
ORF1ab/nsp12742V742VgtGgtT310B.1.1770.00004
ORF1ab/nsp12742V742MGtgAtg1010B.1.177.650.006653
ORF1ab/nsp12742V742VgtGgtA610B.1.617.20.000023
ORF1ab/nsp12742V742VgtGgtT410B.1.617.20.000015
ORF1ab/nsp12742V742LGtgTtg99AY.1030.000056
ORF1ab/nsp12742V742LGtgTtg88AY.690.001493
ORF1ab/nsp12742V742VgtGgtT58B.1.10.000091
ORF1ab/nsp12742V742VgtGgtA38B.1.10.000054
ORF1ab/nsp12742V742AgTggCg88B.1.1.70.000007
ORF1ab/nsp12742V742GgTggGg88B.1.20.00007
ORF1ab/nsp12742V742EgTggAg66All0.000001
ORF1ab/nsp12742V742VgtGgtT66AY.1030.000037
ORF1ab/nsp12742V742VgtGgtT36B.10.000027
ORF1ab/nsp12742V742VgtGgtA36B.10.000027
ORF1ab/nsp12742V742LGtgTtg66B.1.1.500.004073
ORF1ab/nsp12742V742VgtGgtA46B.1.4290.000094
ORF1ab/nsp12742V742VgtGgtT26B.1.4290.000047
ORF1ab/nsp12742V742LGtgTtg55AY.1020.000133
ORF1ab/nsp12742V742LGtgTtg55AY.350.001165
ORF1ab/nsp12742V742LGtgTtg55AY.430.000022
ORF1ab/nsp12742V742MGtgAtg55B.1.1.3240.263158
ORF1ab/nsp12742V742VgtGgtA55B.1.1.3960.227273
ORF1ab/nsp12742V742VgtGgtA45B.1.20.000035
ORF1ab/nsp12742V742VgtGgtC15B.1.20.000009
ORF1ab/nsp12742V742KGTgAAg34All0.000001
ORF1ab/nsp12742V742del1Gtg-tg34All0.000001
ORF1ab/nsp12742V742KGTGAAA14All0
ORF1ab/nsp12742V742del1GTgA-g14All0
ORF1ab/nsp12742V742AgTggCg44AY.30.00004
ORF1ab/nsp12742V742VgtGgtA44AY.370.001264
ORF1ab/nsp12742V742VgtGgtC24AY.4.20.000043
ORF1ab/nsp12742V742VgtGgtT14AY.4.20.000022
ORF1ab/nsp12742V742VgtGgtA14AY.4.20.000022
ORF1ab/nsp12742V742LGtgTtg44AY.470.000124
ORF1ab/nsp12742V742VgtGgtT24AY.470.000062
ORF1ab/nsp12742V742VgtGgtA24AY.470.000062
ORF1ab/nsp12742V742VgtGgtC44AY.520.003257
ORF1ab/nsp12742V742delGTG---44B.1.1.70.000004
ORF1ab/nsp12742V742VgtGgtT44B.1.1110.0047
ORF1ab/nsp12742V742LGtgTtg44B.1.20.000035
ORF1ab/nsp12742V742LGtgTtg44B.1.3510.000119
ORF1ab/nsp12742V742VgtGgtA33AY.1020.00008
ORF1ab/nsp12742V742MGtgAtg33AY.1030.000019
ORF1ab/nsp12742V742VgtGgtT33AY.200.000117
ORF1ab/nsp12742V742LGtgTtg33AY.250.000018
ORF1ab/nsp12742V742LGtgTtg33AY.380.001498
ORF1ab/nsp12742V742LGtgTtg33AY.390.000074
ORF1ab/nsp12742V742MGtgAtg33AY.430.000013
ORF1ab/nsp12742V742VgtGgtA33AY.440.000018
ORF1ab/nsp12742V742LGtgTtg33AY.980.000237
ORF1ab/nsp12742V742LGtgTtg33B.10.000027
ORF1ab/nsp12742V742MGtgAtg33B.1.1.70.000003
ORF1ab/nsp12742V742VgtGgtT33B.1.1600.000094
ORF1ab/nsp12742V742VgtGgtA33B.1.258.170.000312
ORF1ab/nsp12742V742AgTggCg33B.30.002492
ORF1ab/nsp12742V742VgtGgtA23D.20.00015
ORF1ab/nsp12742V742VgtGgtT13D.20.000075
ORF1ab/nsp12742V742LGtgTtg23P.10.000032
ORF1ab/nsp12742V742LGtgCtg13P.10.000016
ORF1ab/nsp12742V742RGTgAGg220.111111
ORF1ab/nsp12742V742EgTggAg220.111111
ORF1ab/nsp12742V742AgTggCg220.111111
ORF1ab/nsp12742V742KGTgAAg220.111111
ORF1ab/nsp12742V742MGtgAtg220.111111
ORF1ab/nsp12742V742RGTgAGg22All0
ORF1ab/nsp12742V742EgTggAg22AY.1020.000053
ORF1ab/nsp12742V742AgTggCg22AY.1040.003968
ORF1ab/nsp12742V742MGtgAtg22AY.1100.000225
ORF1ab/nsp12742V742VgtGgtT22AY.1190.000071
ORF1ab/nsp12742V742LGtgTtg22AY.190.002281
ORF1ab/nsp12742V742AgTggCg22AY.250.000012
ORF1ab/nsp12742V742MGtgAtg22AY.270.000129
ORF1ab/nsp12742V742AgTggCg22AY.330.000134
ORF1ab/nsp12742V742del1Gtg-tg12AY.440.000006
ORF1ab/nsp12742V742del1GTgA-g12AY.440.000006
ORF1ab/nsp12742V742LGtgTtg22AY.540.000191
ORF1ab/nsp12742V742AgTggCg22AY.60.000082
ORF1ab/nsp12742V742AgTggCg22B.10.000018
ORF1ab/nsp12742V742LGtgTtg22B.1.10.000036
ORF1ab/nsp12742V742VgtGgtA22B.1.177.120.000303
ORF1ab/nsp12742V742MGtgAtg22B.1.177.440.001038
ORF1ab/nsp12742V742VgtGgtT12B.1.2210.000071
ORF1ab/nsp12742V742VgtGgtA12B.1.2210.000071
ORF1ab/nsp12742V742VgtGgtA12B.1.5260.000024
ORF1ab/nsp12742V742VgtGgtT12B.1.5260.000024
ORF1ab/nsp12742V742AgTggCg22B.1.617.20.000008
ORF1ab/nsp12742V742GgTGgGA12B.3.10.001658
ORF1ab/nsp12742V742GgTggGg12B.3.10.001658
ORF1ab/nsp12742V742LGtgTtg11A.10.000282
ORF1ab/nsp12742V742del2GTG--C11All0
ORF1ab/nsp12742V742XGTGTAA11All0
ORF1ab/nsp12742V742MGtgAtg11AY.1020.000027
ORF1ab/nsp12742V742VgtGgtT11AY.1130.000142
ORF1ab/nsp12742V742LGtgTtg11AY.1160.000287
ORF1ab/nsp12742V742VgtGgtA11AY.1180.000063
ORF1ab/nsp12742V742MGtgAtg11AY.1200.000037
ORF1ab/nsp12742V742AgTggCg11AY.200.000039
ORF1ab/nsp12742V742MGtgAtg11AY.230.00007
ORF1ab/nsp12742V742VgtGgtA11AY.250.000006
ORF1ab/nsp12742V742MGtgAtg11AY.250.000006
ORF1ab/nsp12742V742VgtGgtA11AY.260.000028
ORF1ab/nsp12742V742LGtgTtg11AY.270.000065
ORF1ab/nsp12742V742LGtgTtg11AY.290.000016
ORF1ab/nsp12742V742VgtGgtT11AY.290.000016
ORF1ab/nsp12742V742VgtGgtA11AY.30.00001
ORF1ab/nsp12742V742LGtgTtg11AY.30.00001
ORF1ab/nsp12742V742delGTG---11AY.30.00001
ORF1ab/nsp12742V742AgTggCg11AY.350.000233
ORF1ab/nsp12742V742VgtGgtT11AY.390.000025
ORF1ab/nsp12742V742VgtGgtT11AY.39.1.10.000725
ORF1ab/nsp12742V742delGTG---11AY.40.000002
ORF1ab/nsp12742V742LGtgTtg11AY.420.00004
ORF1ab/nsp12742V742del2GTG--C11AY.430.000004
ORF1ab/nsp12742V742AgTggCg11AY.430.000004
ORF1ab/nsp12742V742EgTggAg11AY.430.000004
ORF1ab/nsp12742V742VgtGgtT11AY.460.000104
ORF1ab/nsp12742V742LGtgTtg11AY.460.000104
ORF1ab/nsp12742V742LGtgTtg11AY.50.000021
ORF1ab/nsp12742V742VgtGgtT11AY.60.000041
ORF1ab/nsp12742V742LGtgTtg11AY.610.000105
ORF1ab/nsp12742V742VgtGgtT11AY.610.000105
ORF1ab/nsp12742V742delGTG---11AY.670.000464
ORF1ab/nsp12742V742KGTgAAg11AY.670.000464
ORF1ab/nsp12742V742AgTggCg11AY.750.000056
ORF1ab/nsp12742V742LGtgTtg11AY.75.10.00018
ORF1ab/nsp12742V742LGtgTtg11AY.770.001127
ORF1ab/nsp12742V742LGtgTtg11AY.840.000437
ORF1ab/nsp12742V742LGtgTtg11AY.90.000068
ORF1ab/nsp12742V742delGTG---11AY.90.000068
ORF1ab/nsp12742V742MGtgAtg11AY.9.20.000037
ORF1ab/nsp12742V742VgtGgtA11AY.920.000287
ORF1ab/nsp12742V742LGtgTtg11AY.970.001701
ORF1ab/nsp12742V742MGtgAtg11B0.000128
ORF1ab/nsp12742V742del1Gtg-tg11B0.000128
ORF1ab/nsp12742V742delGTG---11B.10.000009
ORF1ab/nsp12742V742MGtgAtg11B.1.10.000018
ORF1ab/nsp12742V742KGTGAAA11B.1.10.000018
ORF1ab/nsp12742V742XGTGTAA11B.1.10.000018
ORF1ab/nsp12742V742VgtGgtC11B.1.1.3060.000438
ORF1ab/nsp12742V742LGtgTtg11B.1.1.3170.000412
ORF1ab/nsp12742V742VgtGgtT11B.1.1.330.000421
ORF1ab/nsp12742V742MGtgAtg11B.1.1.3550.015385
ORF1ab/nsp12742V742LGtgTtg11B.1.1.3690.000446
ORF1ab/nsp12742V742AgTggCg11B.1.1.3720.000689
ORF1ab/nsp12742V742VgtGgtA11B.1.1.3750.011905
ORF1ab/nsp12742V742VgtGgtT11B.1.1.620.027027
ORF1ab/nsp12742V742delGTG---11B.1.1.700.000341
ORF1ab/nsp12742V742LGtgTtg11B.1.1.890.006061
ORF1ab/nsp12742V742LGtgTtg11B.1.110.30.000718
ORF1ab/nsp12742V742LGtgTtg11B.1.1260.001276
ORF1ab/nsp12742V742MGtgAtg11B.1.160.160.000929
ORF1ab/nsp12742V742delGTG---11B.1.1770.000013
ORF1ab/nsp12742V742AgTggCg11B.1.177.190.001431
ORF1ab/nsp12742V742AgTggCg11B.1.177.230.003236
ORF1ab/nsp12742V742LGtgCtg11B.1.177.440.000519
ORF1ab/nsp12742V742delGTG---11B.1.177.510.004566
ORF1ab/nsp12742V742AgTggCg11B.1.177.600.000218
ORF1ab/nsp12742V742LGtgCtg11B.1.177.830.001481
ORF1ab/nsp12742V742MGtgAtg11B.1.177.860.000183
ORF1ab/nsp12742V742MGtgAtg11B.1.20.000009
ORF1ab/nsp12742V742del1Gtg-tg11B.1.20.000009
ORF1ab/nsp12742V742EgTggAg11B.1.20.000009
ORF1ab/nsp12742V742AgTggCg11B.1.20.000009
ORF1ab/nsp12742V742MGtgAtg11B.1.2210.000071
ORF1ab/nsp12742V742VgtGgtA11B.1.221.10.002907
ORF1ab/nsp12742V742VgtGgtA11B.1.2320.000537
ORF1ab/nsp12742V742LGtgTtg11B.1.2580.000067
ORF1ab/nsp12742V742delGTG---11B.1.2580.000067
ORF1ab/nsp12742V742VgtGgtT11B.1.3510.00003
ORF1ab/nsp12742V742LGtgTtg11B.1.4000.000429
ORF1ab/nsp12742V742VgtGgtT11B.1.4250.002994
ORF1ab/nsp12742V742LGtgTtg11B.1.4270.00005
ORF1ab/nsp12742V742VgtGgtA11B.1.4320.011236
ORF1ab/nsp12742V742VgtGgtT11B.1.4680.005714
ORF1ab/nsp12742V742AgTggCg11B.1.5170.000427
ORF1ab/nsp12742V742VgtGgtT11B.1.5170.000427
ORF1ab/nsp12742V742LGtgTtg11B.1.5260.000024
ORF1ab/nsp12742V742VgtGgtA11B.1.5820.000491
ORF1ab/nsp12742V742MGtgAtg11B.1.5820.000491
ORF1ab/nsp12742V742MGtgAtg11B.1.5950.000261
ORF1ab/nsp12742V742VgtGgtT11B.1.5960.000087
ORF1ab/nsp12742V742MGtgAtg11B.1.617.20.000004
ORF1ab/nsp12742V742delGTG---11B.1.617.20.000004
ORF1ab/nsp12742V742LGtgTtg11B.1.6230.000536
ORF1ab/nsp12742V742AgTggCg11B.1.6370.000073
ORF1ab/nsp12742V742VgtGgtA11B.3.10.001658
ORF1ab/nsp12742V742VgtGgtT11B.60.00091
ORF1ab/nsp12742V742LGtgTtg11D.20.000075
ORF1ab/nsp12742V742MGtgAtg11P.10.000016
ORF1ab/nsp12742V742AgTggCg11P.1.150.000232
ORF1ab/nsp12742V742VgtGgtA11P.1.70.000319
ORF1ab/nsp12742V742delGTG---11Q.10.000126
ORF1ab/nsp12742V742AgTggCg11Q.80.000165
ORF1ab/nsp12742V742AgTggCg11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.