CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 734

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12734N734NN5126NsynaaTaaC14481448115640-15642
ORF1ab/nsp12734N734SN5126SnonsynaAtaGt377377115640-15642
ORF1ab/nsp12734N734DN5126DnonsynAatGat3593580.99721415640-15642
ORF1ab/nsp12734N734DN5126DnonsynAaTGaC35910.0027855215640-15642
ORF1ab/nsp12734N734TN5126TnonsynaAtaCt1191170.98319315640-15642
ORF1ab/nsp12734N734TN5126TnonsynaATaCC11920.016806715640-15642
ORF1ab/nsp12734N734YN5126YnonsynAatTat5656115640-15642
ORF1ab/nsp12734N734delN5126deldelAAT---2525115640-15642
ORF1ab/nsp12734N734HN5126HnonsynAatCat1111115640-15642
ORF1ab/nsp12734N734KN5126KnonsynaaTaaG950.55555615640-15642
ORF1ab/nsp12734N734KN5126KnonsynaaTaaA940.44444415640-15642
ORF1ab/nsp12734N734IN5126InonsynaAtaTt22115640-15642
ORF1ab/nsp12734N734FN5126FnonsynAAtTTt11115640-15642
ORF1ab/nsp12734N734del1N5126del1delAat-at11115640-15642

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12734N734NaaTaaC14481448All0.000277
ORF1ab/nsp12734N734NaaTaaC12061206B.1.1.3480.960191
ORF1ab/nsp12734N734SaAtaGt377377All0.000072
ORF1ab/nsp12734N734DAatGat358359All0.000068
ORF1ab/nsp12734N734DAaTGaC1359All0
ORF1ab/nsp12734N734SaAtaGt174174AY.250.001047
ORF1ab/nsp12734N734DAatGat127127B.1.1.70.000114
ORF1ab/nsp12734N734TaAtaCt117119All0.000022
ORF1ab/nsp12734N734TaATaCC2119All0
ORF1ab/nsp12734N734DAatGat9293C.370.010678
ORF1ab/nsp12734N734DAaTGaC193C.370.000116
ORF1ab/nsp12734N734NaaTaaC6363B.1.10.001143
ORF1ab/nsp12734N734YAatTat5656All0.000011
ORF1ab/nsp12734N734TaAtaCt5555P.10.000866
ORF1ab/nsp12734N734SaAtaGt4242B.1.1.70.000038
ORF1ab/nsp12734N734SaAtaGt3939AY.1030.000242
ORF1ab/nsp12734N734NaaTaaC3636B.10.00033
ORF1ab/nsp12734N734DAatGat2727B.1.5760.024479
ORF1ab/nsp12734N734delAAT---2525All0.000005
ORF1ab/nsp12734N734TaAtaCt2525B.1.1.70.000022
ORF1ab/nsp12734N734DAatGat2424B.1.177.170.019704
ORF1ab/nsp12734N734SaAtaGt1313B.1.20.000114
ORF1ab/nsp12734N734YAatTat1313B.1.4290.000306
ORF1ab/nsp12734N734SaAtaGt1313P.1.140.000621
ORF1ab/nsp12734N734DAatGat1212B.1.617.20.000045
ORF1ab/nsp12734N734HAatCat1111All0.000002
ORF1ab/nsp12734N734NaaTaaC1111AY.140.000968
ORF1ab/nsp12734N734NaaTaaC1111B.1.1.3070.027848
ORF1ab/nsp12734N734delAAT---1111B.1.1.70.00001
ORF1ab/nsp12734N734NaaTaaC1010AY.250.00006
ORF1ab/nsp12734N734TaAtaCt1010AY.40.000016
ORF1ab/nsp12734N734NaaTaaC1010AY.90.000676
ORF1ab/nsp12734N734DAatGat1010B.1.2580.000665
ORF1ab/nsp12734N734KaaTaaG59All0.000001
ORF1ab/nsp12734N734KaaTaaA49All0.000001
ORF1ab/nsp12734N734SaAtaGt99B.1.5250.001018
ORF1ab/nsp12734N734NaaTaaC99B.1.617.20.000034
ORF1ab/nsp12734N734SaAtaGt88B.1.617.20.00003
ORF1ab/nsp12734N734NaaTaaC77AY.40.000011
ORF1ab/nsp12734N734YAatTat77B.1.1.70.000006
ORF1ab/nsp12734N734YAatTat77B.1.3290.004253
ORF1ab/nsp12734N734YAatTat77B.1.5260.000165
ORF1ab/nsp12734N734SaAtaGt77P.10.00011
ORF1ab/nsp12734N734SaAtaGt77W.40.009459
ORF1ab/nsp12734N734SaAtaGt66AY.40.000009
ORF1ab/nsp12734N734NaaTaaC66B.1.1.70.000005
ORF1ab/nsp12734N734DAatGat66B.1.177.70.000989
ORF1ab/nsp12734N734DAatGat66B.1.20.000053
ORF1ab/nsp12734N734DAatGat66B.1.4000.002574
ORF1ab/nsp12734N734NaaTaaC55AY.30.00005
ORF1ab/nsp12734N734DAatGat55B.10.000046
ORF1ab/nsp12734N734SaAtaGt44AY.50.000083
ORF1ab/nsp12734N734TaAtaCt44AY.9.20.000147
ORF1ab/nsp12734N734SaAtaGt44AY.98.10.000194
ORF1ab/nsp12734N734SaAtaGt44B.10.000037
ORF1ab/nsp12734N734NaaTaaC44B.1.1.2840.00043
ORF1ab/nsp12734N734NaaTaaC44B.1.1.4170.010811
ORF1ab/nsp12734N734NaaTaaC44B.1.20.000035
ORF1ab/nsp12734N734SaAtaGt44B.1.6340.013699
ORF1ab/nsp12734N734DAatGat33AY.1030.000019
ORF1ab/nsp12734N734TaAtaCt33AY.1200.000112
ORF1ab/nsp12734N734DAatGat33AY.1210.000406
ORF1ab/nsp12734N734TaAtaCt33AY.250.000018
ORF1ab/nsp12734N734SaAtaGt33AY.390.000074
ORF1ab/nsp12734N734DAatGat33AY.40.000005
ORF1ab/nsp12734N734KaaTaaG33AY.40.000005
ORF1ab/nsp12734N734HAatCat33AY.470.000093
ORF1ab/nsp12734N734NaaTaaC33AY.98.10.000145
ORF1ab/nsp12734N734YAatTat33B.10.000027
ORF1ab/nsp12734N734NaaTaaC33B.1.1.1800.032258
ORF1ab/nsp12734N734YAatTat33B.1.1.250.001706
ORF1ab/nsp12734N734NaaTaaC33B.1.1.2690.00406
ORF1ab/nsp12734N734NaaTaaC33B.1.1.3040.008427
ORF1ab/nsp12734N734DAatGat33B.1.3510.000089
ORF1ab/nsp12734N734TaAtaCt33B.1.360.000438
ORF1ab/nsp12734N734SaAtaGt33B.1.36.170.001482
ORF1ab/nsp12734N734DAatGat33B.1.4290.000071
ORF1ab/nsp12734N734NaaTaaC33P.20.00056
ORF1ab/nsp12734N734HAatCat220.111111
ORF1ab/nsp12734N734TaATaCC220.111111
ORF1ab/nsp12734N734KaaTaaG220.111111
ORF1ab/nsp12734N734NaaTaaC22AE.80.000978
ORF1ab/nsp12734N734IaAtaTt22All0
ORF1ab/nsp12734N734SaAtaGt22AY.1020.000053
ORF1ab/nsp12734N734TaAtaCt22AY.200.000078
ORF1ab/nsp12734N734YAatTat22AY.250.000012
ORF1ab/nsp12734N734DAatGat22AY.250.000012
ORF1ab/nsp12734N734SaAtaGt22AY.260.000057
ORF1ab/nsp12734N734DAatGat22AY.30.00002
ORF1ab/nsp12734N734NaaTaaC22AY.39.10.000079
ORF1ab/nsp12734N734HAatCat22AY.40.000003
ORF1ab/nsp12734N734NaaTaaC22AY.420.00008
ORF1ab/nsp12734N734SaAtaGt22AY.440.000012
ORF1ab/nsp12734N734SaAtaGt22AY.990.002099
ORF1ab/nsp12734N734SaAtaGt22AY.99.10.003106
ORF1ab/nsp12734N734delAAT---22B.10.000018
ORF1ab/nsp12734N734YAatTat22B.1.10.000036
ORF1ab/nsp12734N734DAatGat22B.1.10.000036
ORF1ab/nsp12734N734SaAtaGt22B.1.10.000036
ORF1ab/nsp12734N734NaaTaaC22B.1.1.1740.006757
ORF1ab/nsp12734N734YAatTat22B.1.1.2790.002242
ORF1ab/nsp12734N734NaaTaaC22B.1.1.280.000622
ORF1ab/nsp12734N734SaAtaGt22B.1.1.3120.003824
ORF1ab/nsp12734N734SaAtaGt22B.1.1770.000026
ORF1ab/nsp12734N734NaaTaaC22B.1.2430.000139
ORF1ab/nsp12734N734SaAtaGt22B.1.4000.000858
ORF1ab/nsp12734N734DAatGat22B.1.4280.002041
ORF1ab/nsp12734N734DAatGat22B.1.438.10.000215
ORF1ab/nsp12734N734DAatGat22B.1.466.20.000782
ORF1ab/nsp12734N734DAatGat22B.1.5260.000047
ORF1ab/nsp12734N734SaAtaGt22B.1.5260.000047
ORF1ab/nsp12734N734SaAtaGt22B.1.564.10.003155
ORF1ab/nsp12734N734delAAT---22B.1.617.20.000008
ORF1ab/nsp12734N734YAatTat22P.10.000032
ORF1ab/nsp12734N734DAatGat22P.10.000032
ORF1ab/nsp12734N734TaAtaCt22P.1.140.000096
ORF1ab/nsp12734N734NaaTaaC22Q.30.00029
ORF1ab/nsp12734N734IaAtaTt11A0.000387
ORF1ab/nsp12734N734del1Aat-at11All0
ORF1ab/nsp12734N734FAAtTTt11All0
ORF1ab/nsp12734N734NaaTaaC11AY.1020.000027
ORF1ab/nsp12734N734YAatTat11AY.1030.000006
ORF1ab/nsp12734N734SaAtaGt11AY.1070.000466
ORF1ab/nsp12734N734TaAtaCt11AY.1100.000113
ORF1ab/nsp12734N734NaaTaaC11AY.230.00007
ORF1ab/nsp12734N734YAatTat11AY.30.00001
ORF1ab/nsp12734N734KaaTaaA11AY.30.00001
ORF1ab/nsp12734N734FAAtTTt11AY.300.000396
ORF1ab/nsp12734N734NaaTaaC11AY.390.000025
ORF1ab/nsp12734N734delAAT---11AY.40.000002
ORF1ab/nsp12734N734YAatTat11AY.40.000002
ORF1ab/nsp12734N734NaaTaaC11AY.4.20.000022
ORF1ab/nsp12734N734TaAtaCt11AY.4.20.000022
ORF1ab/nsp12734N734DAatGat11AY.4.30.000842
ORF1ab/nsp12734N734delAAT---11AY.4.50.000107
ORF1ab/nsp12734N734KaaTaaA11AY.430.000004
ORF1ab/nsp12734N734TaAtaCt11AY.440.000006
ORF1ab/nsp12734N734NaaTaaC11AY.440.000006
ORF1ab/nsp12734N734NaaTaaC11AY.450.000122
ORF1ab/nsp12734N734SaAtaGt11AY.470.000031
ORF1ab/nsp12734N734NaaTaaC11AY.50.000021
ORF1ab/nsp12734N734YAatTat11AY.50.000021
ORF1ab/nsp12734N734TaAtaCt11AY.50.000021
ORF1ab/nsp12734N734DAatGat11AY.50.000021
ORF1ab/nsp12734N734SaAtaGt11AY.590.00053
ORF1ab/nsp12734N734DAatGat11AY.60.000041
ORF1ab/nsp12734N734KaaTaaA11AY.670.000464
ORF1ab/nsp12734N734NaaTaaC11AY.7.10.000113
ORF1ab/nsp12734N734NaaTaaC11AY.730.000665
ORF1ab/nsp12734N734SaAtaGt11AY.75.10.00018
ORF1ab/nsp12734N734SaAtaGt11AY.820.001357
ORF1ab/nsp12734N734delAAT---11AY.90.000068
ORF1ab/nsp12734N734SaAtaGt11AY.9.20.000037
ORF1ab/nsp12734N734YAatTat11AY.99.20.000092
ORF1ab/nsp12734N734NaaTaaC11B0.000128
ORF1ab/nsp12734N734SaAtaGt11B0.000128
ORF1ab/nsp12734N734TaAtaCt11B0.000128
ORF1ab/nsp12734N734DAatGat11B0.000128
ORF1ab/nsp12734N734TaAtaCt11B.10.000009
ORF1ab/nsp12734N734del1Aat-at11B.1.10.000018
ORF1ab/nsp12734N734NaaTaaC11B.1.1.10.000327
ORF1ab/nsp12734N734NaaTaaC11B.1.1.100.001115
ORF1ab/nsp12734N734NaaTaaC11B.1.1.1710.003676
ORF1ab/nsp12734N734NaaTaaC11B.1.1.1980.001468
ORF1ab/nsp12734N734NaaTaaC11B.1.1.2140.000055
ORF1ab/nsp12734N734NaaTaaC11B.1.1.2200.001859
ORF1ab/nsp12734N734delAAT---11B.1.1.3110.000358
ORF1ab/nsp12734N734TaAtaCt11B.1.1.3540.004386
ORF1ab/nsp12734N734NaaTaaC11B.1.1.3980.003226
ORF1ab/nsp12734N734NaaTaaC11B.1.1.4160.000905
ORF1ab/nsp12734N734NaaTaaC11B.1.1.4420.018519
ORF1ab/nsp12734N734NaaTaaC11B.1.1.4620.008621
ORF1ab/nsp12734N734DAatGat11B.1.1.500.000679
ORF1ab/nsp12734N734NaaTaaC11B.1.1.5140.038462
ORF1ab/nsp12734N734DAatGat11B.1.1.5190.00004
ORF1ab/nsp12734N734SaAtaGt11B.1.1.5190.00004
ORF1ab/nsp12734N734DAatGat11B.1.1.5250.005464
ORF1ab/nsp12734N734SaAtaGt11B.1.1.5260.003546
ORF1ab/nsp12734N734delAAT---11B.1.1.700.000341
ORF1ab/nsp12734N734NaaTaaC11B.1.1.890.006061
ORF1ab/nsp12734N734delAAT---11B.1.1770.000013
ORF1ab/nsp12734N734DAatGat11B.1.1770.000013
ORF1ab/nsp12734N734YAatTat11B.1.1770.000013
ORF1ab/nsp12734N734TaAtaCt11B.1.1770.000013
ORF1ab/nsp12734N734delAAT---11B.1.177.510.004566
ORF1ab/nsp12734N734NaaTaaC11B.1.177.810.000189
ORF1ab/nsp12734N734delAAT---11B.1.177.870.000728
ORF1ab/nsp12734N734YAatTat11B.1.20.000009
ORF1ab/nsp12734N734IaAtaTt11B.1.20.000009
ORF1ab/nsp12734N734KaaTaaA11B.1.20.000009
ORF1ab/nsp12734N734DAatGat11B.1.2210.000071
ORF1ab/nsp12734N734NaaTaaC11B.1.2210.000071
ORF1ab/nsp12734N734HAatCat11B.1.2210.000071
ORF1ab/nsp12734N734NaaTaaC11B.1.230.006061
ORF1ab/nsp12734N734YAatTat11B.1.2320.000537
ORF1ab/nsp12734N734delAAT---11B.1.2580.000067
ORF1ab/nsp12734N734SaAtaGt11B.1.2580.000067
ORF1ab/nsp12734N734NaaTaaC11B.1.258.170.000104
ORF1ab/nsp12734N734TaAtaCt11B.1.36.290.000517
ORF1ab/nsp12734N734NaaTaaC11B.1.3960.000706
ORF1ab/nsp12734N734DAatGat11B.1.416.10.001563
ORF1ab/nsp12734N734SaAtaGt11B.1.4260.001009
ORF1ab/nsp12734N734SaAtaGt11B.1.4270.00005
ORF1ab/nsp12734N734NaaTaaC11B.1.4270.00005
ORF1ab/nsp12734N734TaAtaCt11B.1.5160.001957
ORF1ab/nsp12734N734NaaTaaC11B.1.5350.028571
ORF1ab/nsp12734N734SaAtaGt11B.1.5760.000907
ORF1ab/nsp12734N734HAatCat11B.1.5820.000491
ORF1ab/nsp12734N734NaaTaaC11B.1.6090.000479
ORF1ab/nsp12734N734HAatCat11B.1.617.20.000004
ORF1ab/nsp12734N734SaAtaGt11B.1.6210.000089
ORF1ab/nsp12734N734NaaTaaC11B.1.621.10.000506
ORF1ab/nsp12734N734SaAtaGt11C.370.000116
ORF1ab/nsp12734N734NaaTaaC11C.370.000116
ORF1ab/nsp12734N734DAatGat11D.20.000075
ORF1ab/nsp12734N734HAatCat11P.10.000016
ORF1ab/nsp12734N734NaaTaaC11P.1.160.000374
ORF1ab/nsp12734N734DAatGat11P.1.70.000319
ORF1ab/nsp12734N734delAAT---11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.