CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 594

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12594F594FF4986FsynttCttT26822682115220-15222
ORF1ab/nsp12594F594CF4986CnonsyntTctGc200200115220-15222
ORF1ab/nsp12594F594LF4986LnonsynTtcCtc61360.59016415220-15222
ORF1ab/nsp12594F594LF4986LnonsynttCttA61220.36065615220-15222
ORF1ab/nsp12594F594LF4986LnonsynttCttG6130.049180315220-15222
ORF1ab/nsp12594F594delF4986deldelTTC---4343115220-15222
ORF1ab/nsp12594F594SF4986SnonsyntTctCc66115220-15222
ORF1ab/nsp12594F594VF4986VnonsynTtcGtc44115220-15222
ORF1ab/nsp12594F594del1F4986del1delttCtt-420.515220-15222
ORF1ab/nsp12594F594del1F4986del1delTtc-tc420.515220-15222
ORF1ab/nsp12594F594del2F4986del2delTTc--c320.66666715220-15222
ORF1ab/nsp12594F594del2F4986del2deltTCt--310.33333315220-15222
ORF1ab/nsp12594F594YF4986YnonsyntTctAc22115220-15222
ORF1ab/nsp12594F594IF4986InonsynTtcAtc11115220-15222

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12594F594FttCttT26822682All0.000513
ORF1ab/nsp12594F594FttCttT486486B.1.1.70.000435
ORF1ab/nsp12594F594FttCttT336336AY.40.000523
ORF1ab/nsp12594F594CtTctGc200200All0.000038
ORF1ab/nsp12594F594CtTctGc192192B.1.1.70.000172
ORF1ab/nsp12594F594FttCttT170170B.1.617.20.00064
ORF1ab/nsp12594F594FttCttT163163AY.250.00098
ORF1ab/nsp12594F594FttCttT148148B.1.20.001303
ORF1ab/nsp12594F594FttCttT130130B.1.1.2280.396341
ORF1ab/nsp12594F594FttCttT115115AY.1020.003049
ORF1ab/nsp12594F594FttCttT8989N.50.157244
ORF1ab/nsp12594F594FttCttT6767P.10.001056
ORF1ab/nsp12594F594LTtcCtc3661All0.000007
ORF1ab/nsp12594F594LttCttA2261All0.000004
ORF1ab/nsp12594F594LttCttG361All0.000001
ORF1ab/nsp12594F594FttCttT6060B.1.1.2240.857143
ORF1ab/nsp12594F594FttCttT5656AY.260.001585
ORF1ab/nsp12594F594FttCttT5353AY.50.001094
ORF1ab/nsp12594F594FttCttT4444AY.460.00458
ORF1ab/nsp12594F594delTTC---4343All0.000008
ORF1ab/nsp12594F594FttCttT4040AY.440.000243
ORF1ab/nsp12594F594FttCttT3838AY.470.001182
ORF1ab/nsp12594F594FttCttT3636AY.1100.004057
ORF1ab/nsp12594F594FttCttT3636AY.430.000159
ORF1ab/nsp12594F594FttCttT3030AY.1030.000186
ORF1ab/nsp12594F594FttCttT2424B.1.3510.000713
ORF1ab/nsp12594F594FttCttT2323B.1.10.000417
ORF1ab/nsp12594F594delTTC---2323B.1.1.70.000021
ORF1ab/nsp12594F594FttCttT1818AY.30.000179
ORF1ab/nsp12594F594FttCttT1818B.10.000165
ORF1ab/nsp12594F594FttCttT1818B.1.177.830.026667
ORF1ab/nsp12594F594FttCttT1818P.1.140.00086
ORF1ab/nsp12594F594FttCttT1717AY.540.001621
ORF1ab/nsp12594F594FttCttT1616AY.390.000395
ORF1ab/nsp12594F594FttCttT1616B.1.5260.000376
ORF1ab/nsp12594F594FttCttT1515B.1.2430.001044
ORF1ab/nsp12594F594FttCttT1515B.1.3810.117188
ORF1ab/nsp12594F594FttCttT1515B.1.4290.000353
ORF1ab/nsp12594F594FttCttT1313B.1.1.4340.004531
ORF1ab/nsp12594F594LttCttA812AY.40.000012
ORF1ab/nsp12594F594LTtcCtc312AY.40.000005
ORF1ab/nsp12594F594LttCttG112AY.40.000002
ORF1ab/nsp12594F594FttCttT1212AY.690.00224
ORF1ab/nsp12594F594FttCttT1111AY.1190.000388
ORF1ab/nsp12594F594FttCttT1111B.1.1.5190.000437
ORF1ab/nsp12594F594FttCttT1111B.1.4270.000555
ORF1ab/nsp12594F594FttCttT1010B.1.6370.000731
ORF1ab/nsp12594F594FttCttT99AY.98.10.000436
ORF1ab/nsp12594F594FttCttT99B.1.1.3060.003946
ORF1ab/nsp12594F594FttCttT99B.350.070312
ORF1ab/nsp12594F594FttCttT88AY.330.000534
ORF1ab/nsp12594F594FttCttT88B.1.1600.00025
ORF1ab/nsp12594F594FttCttT88P.1.120.003872
ORF1ab/nsp12594F594FttCttT77AY.290.00011
ORF1ab/nsp12594F594FttCttT77B.1.1.330.002946
ORF1ab/nsp12594F594StTctCc66All0.000001
ORF1ab/nsp12594F594FttCttT66B.1.1.2220.001224
ORF1ab/nsp12594F594FttCttT66B.1.1.3170.00247
ORF1ab/nsp12594F594LTtcCtc66B.1.1.70.000005
ORF1ab/nsp12594F594FttCttT66B.1.1770.000079
ORF1ab/nsp12594F594FttCttT55A.2.50.002495
ORF1ab/nsp12594F594FttCttT55AY.1170.000423
ORF1ab/nsp12594F594FttCttT55AY.4.20.000108
ORF1ab/nsp12594F594FttCttT55AY.400.004822
ORF1ab/nsp12594F594FttCttT55AY.980.000395
ORF1ab/nsp12594F594LttCttA45B.10.000037
ORF1ab/nsp12594F594LTtcCtc15B.10.000009
ORF1ab/nsp12594F594FttCttT55B.1.5820.002453
ORF1ab/nsp12594F594VTtcGtc44All0.000001
ORF1ab/nsp12594F594del1Ttc-tc24All0
ORF1ab/nsp12594F594del1ttCtt-24All0
ORF1ab/nsp12594F594FttCttT44AY.1210.000541
ORF1ab/nsp12594F594FttCttT44B.1.1.2140.000222
ORF1ab/nsp12594F594FttCttT44B.1.1.3480.003185
ORF1ab/nsp12594F594FttCttT44B.1.617.10.000516
ORF1ab/nsp12594F594del2TTc--c23All0
ORF1ab/nsp12594F594del2tTCt--13All0
ORF1ab/nsp12594F594FttCttT33AY.1060.001005
ORF1ab/nsp12594F594FttCttT33AY.1130.000427
ORF1ab/nsp12594F594FttCttT33AY.130.000483
ORF1ab/nsp12594F594LTtcCtc33AY.290.000047
ORF1ab/nsp12594F594FttCttT33AY.340.000291
ORF1ab/nsp12594F594FttCttT33AY.360.000445
ORF1ab/nsp12594F594delTTC---33AY.40.000005
ORF1ab/nsp12594F594FttCttT33AY.4.40.001227
ORF1ab/nsp12594F594FttCttT33AY.420.000121
ORF1ab/nsp12594F594LTtcCtc23AY.440.000012
ORF1ab/nsp12594F594LttCttA13AY.440.000006
ORF1ab/nsp12594F594FttCttT33AY.830.005172
ORF1ab/nsp12594F594FttCttT33AY.920.000862
ORF1ab/nsp12594F594FttCttT33B.1.1.280.000934
ORF1ab/nsp12594F594FttCttT33B.1.1.3110.001074
ORF1ab/nsp12594F594del1Ttc-tc23B.1.1.70.000002
ORF1ab/nsp12594F594del1ttCtt-13B.1.1.70.000001
ORF1ab/nsp12594F594delTTC---33B.1.1770.00004
ORF1ab/nsp12594F594FttCttT33B.1.177.770.002179
ORF1ab/nsp12594F594FttCttT33B.1.2580.0002
ORF1ab/nsp12594F594FttCttT33B.1.5950.000783
ORF1ab/nsp12594F594FttCttT33B.1.5960.000261
ORF1ab/nsp12594F594FttCttT33B.1.6010.090909
ORF1ab/nsp12594F594FttCttT33B.1.6090.001438
ORF1ab/nsp12594F594LTtcCtc33B.1.617.20.000011
ORF1ab/nsp12594F594FttCttT33B.1.6210.000266
ORF1ab/nsp12594F594FttCttT33Q.30.000435
ORF1ab/nsp12594F594YtTctAc22All0
ORF1ab/nsp12594F594FttCttT22AY.100.00106
ORF1ab/nsp12594F594LttCttG12AY.1030.000006
ORF1ab/nsp12594F594LTtcCtc12AY.1030.000006
ORF1ab/nsp12594F594FttCttT22AY.1160.000574
ORF1ab/nsp12594F594FttCttT22AY.1200.000074
ORF1ab/nsp12594F594FttCttT22AY.140.000176
ORF1ab/nsp12594F594FttCttT22AY.200.000078
ORF1ab/nsp12594F594FttCttT22AY.230.000139
ORF1ab/nsp12594F594FttCttT22AY.300.000791
ORF1ab/nsp12594F594delTTC---22AY.4.50.000215
ORF1ab/nsp12594F594FttCttT22AY.450.000243
ORF1ab/nsp12594F594FttCttT22AY.46.20.001271
ORF1ab/nsp12594F594FttCttT22AY.640.00119
ORF1ab/nsp12594F594FttCttT22AY.7.10.000225
ORF1ab/nsp12594F594FttCttT22AY.740.000231
ORF1ab/nsp12594F594FttCttT22AY.750.000112
ORF1ab/nsp12594F594FttCttT22AY.90.000135
ORF1ab/nsp12594F594CtTctGc22B.10.000018
ORF1ab/nsp12594F594FttCttT22B.1.1.1570.001826
ORF1ab/nsp12594F594FttCttT22B.1.1.1890.003026
ORF1ab/nsp12594F594FttCttT22B.1.1.2690.002706
ORF1ab/nsp12594F594FttCttT22B.1.1.3180.000604
ORF1ab/nsp12594F594FttCttT22B.1.1.5260.007092
ORF1ab/nsp12594F594del2TTc--c22B.1.1.70.000002
ORF1ab/nsp12594F594FttCttT22B.1.177.150.001262
ORF1ab/nsp12594F594FttCttT22B.1.177.210.000153
ORF1ab/nsp12594F594StTctCc22B.1.20.000018
ORF1ab/nsp12594F594FttCttT22B.1.2210.000142
ORF1ab/nsp12594F594FttCttT22B.1.2340.000264
ORF1ab/nsp12594F594FttCttT22B.1.2400.000431
ORF1ab/nsp12594F594FttCttT22B.1.2410.001623
ORF1ab/nsp12594F594FttCttT22B.1.258.170.000208
ORF1ab/nsp12594F594FttCttT22B.1.3060.011429
ORF1ab/nsp12594F594FttCttT22B.1.360.000292
ORF1ab/nsp12594F594FttCttT22B.1.3690.00057
ORF1ab/nsp12594F594FttCttT22B.1.3890.002004
ORF1ab/nsp12594F594FttCttT22C.10.004785
ORF1ab/nsp12594F594FttCttT22P.1.170.000324
ORF1ab/nsp12594F594ITtcAtc11A.2.40.003367
ORF1ab/nsp12594F594FttCttT11A.2.5.10.004808
ORF1ab/nsp12594F594FttCttT11AD.10.004115
ORF1ab/nsp12594F594delTTC---11AD.20.000219
ORF1ab/nsp12594F594ITtcAtc11All0
ORF1ab/nsp12594F594FttCttT11AM.40.003571
ORF1ab/nsp12594F594FttCttT11AY.10.000396
ORF1ab/nsp12594F594FttCttT11AY.1000.000046
ORF1ab/nsp12594F594FttCttT11AY.1180.000063
ORF1ab/nsp12594F594FttCttT11AY.120.10.000321
ORF1ab/nsp12594F594del2tTCt--11AY.190.00114
ORF1ab/nsp12594F594LttCttA11AY.200.000039
ORF1ab/nsp12594F594LttCttA11AY.240.000431
ORF1ab/nsp12594F594LTtcCtc11AY.260.000028
ORF1ab/nsp12594F594FttCttT11AY.270.000065
ORF1ab/nsp12594F594CtTctGc11AY.290.000016
ORF1ab/nsp12594F594LTtcCtc11AY.30.00001
ORF1ab/nsp12594F594delTTC---11AY.330.000067
ORF1ab/nsp12594F594FttCttT11AY.34.10.00051
ORF1ab/nsp12594F594FttCttT11AY.380.000499
ORF1ab/nsp12594F594LttCttG11AY.390.000025
ORF1ab/nsp12594F594VTtcGtc11AY.39.10.00004
ORF1ab/nsp12594F594CtTctGc11AY.40.000002
ORF1ab/nsp12594F594VTtcGtc11AY.4.20.000022
ORF1ab/nsp12594F594FttCttT11AY.4.50.000107
ORF1ab/nsp12594F594VTtcGtc11AY.430.000004
ORF1ab/nsp12594F594LttCttA11AY.430.000004
ORF1ab/nsp12594F594delTTC---11AY.430.000004
ORF1ab/nsp12594F594del1ttCtt-11AY.440.000006
ORF1ab/nsp12594F594FttCttT11AY.46.10.001027
ORF1ab/nsp12594F594LTtcCtc11AY.46.60.000072
ORF1ab/nsp12594F594LTtcCtc11AY.50.000021
ORF1ab/nsp12594F594FttCttT11AY.5.40.000277
ORF1ab/nsp12594F594FttCttT11AY.510.000909
ORF1ab/nsp12594F594LttCttA11AY.520.000814
ORF1ab/nsp12594F594delTTC---11AY.520.000814
ORF1ab/nsp12594F594FttCttT11AY.530.000288
ORF1ab/nsp12594F594FttCttT11AY.60.000041
ORF1ab/nsp12594F594LTtcCtc11AY.610.000105
ORF1ab/nsp12594F594FttCttT11AY.610.000105
ORF1ab/nsp12594F594FttCttT11AY.70.000196
ORF1ab/nsp12594F594FttCttT11AY.710.000475
ORF1ab/nsp12594F594LTtcCtc11AY.750.000056
ORF1ab/nsp12594F594FttCttT11AY.840.000437
ORF1ab/nsp12594F594LTtcCtc11AY.920.000287
ORF1ab/nsp12594F594delTTC---11AY.99.10.001553
ORF1ab/nsp12594F594FttCttT11AZ.10.000867
ORF1ab/nsp12594F594LttCttA11B0.000128
ORF1ab/nsp12594F594FttCttT11B0.000128
ORF1ab/nsp12594F594YtTctAc11B.10.000009
ORF1ab/nsp12594F594StTctCc11B.10.000009
ORF1ab/nsp12594F594FttCttT11B.1.1.1100.090909
ORF1ab/nsp12594F594FttCttT11B.1.1.1170.009709
ORF1ab/nsp12594F594FttCttT11B.1.1.2050.003717
ORF1ab/nsp12594F594CtTctGc11B.1.1.2070.001182
ORF1ab/nsp12594F594FttCttT11B.1.1.2310.003096
ORF1ab/nsp12594F594FttCttT11B.1.1.2840.000107
ORF1ab/nsp12594F594FttCttT11B.1.1.3490.010309
ORF1ab/nsp12594F594FttCttT11B.1.1.3860.066667
ORF1ab/nsp12594F594FttCttT11B.1.1.4090.002833
ORF1ab/nsp12594F594LTtcCtc11B.1.1.4340.000349
ORF1ab/nsp12594F594YtTctAc11B.1.1.5190.00004
ORF1ab/nsp12594F594VTtcGtc11B.1.1.70.000001
ORF1ab/nsp12594F594delTTC---11B.1.1.700.000341
ORF1ab/nsp12594F594FttCttT11B.1.130.002375
ORF1ab/nsp12594F594delTTC---11B.1.1600.000031
ORF1ab/nsp12594F594delTTC---11B.1.160.230.004831
ORF1ab/nsp12594F594LTtcCtc11B.1.177.100.000878
ORF1ab/nsp12594F594delTTC---11B.1.177.160.000664
ORF1ab/nsp12594F594FttCttT11B.1.177.230.003236
ORF1ab/nsp12594F594FttCttT11B.1.177.50.001242
ORF1ab/nsp12594F594delTTC---11B.1.177.540.000606
ORF1ab/nsp12594F594FttCttT11B.1.177.600.000218
ORF1ab/nsp12594F594FttCttT11B.1.177.730.000566
ORF1ab/nsp12594F594LttCttA11B.1.177.790.002342
ORF1ab/nsp12594F594delTTC---11B.1.177.810.000189
ORF1ab/nsp12594F594FttCttT11B.1.177.860.000183
ORF1ab/nsp12594F594FttCttT11B.1.2980.002114
ORF1ab/nsp12594F594FttCttT11B.1.3130.006579
ORF1ab/nsp12594F594LTtcCtc11B.1.3380.008621
ORF1ab/nsp12594F594StTctCc11B.1.3510.00003
ORF1ab/nsp12594F594LTtcCtc11B.1.360.000146
ORF1ab/nsp12594F594FttCttT11B.1.3980.002976
ORF1ab/nsp12594F594FttCttT11B.1.4110.003704
ORF1ab/nsp12594F594FttCttT11B.1.4160.001269
ORF1ab/nsp12594F594LTtcCtc11B.1.4220.000812
ORF1ab/nsp12594F594LTtcCtc11B.1.4270.00005
ORF1ab/nsp12594F594LTtcCtc11B.1.4290.000024
ORF1ab/nsp12594F594FttCttT11B.1.4590.004082
ORF1ab/nsp12594F594FttCttT11B.1.4620.007246
ORF1ab/nsp12594F594FttCttT11B.1.466.20.000391
ORF1ab/nsp12594F594LTtcCtc11B.1.466.20.000391
ORF1ab/nsp12594F594LttCttA11B.1.5260.000024
ORF1ab/nsp12594F594LTtcCtc11B.1.5330.009615
ORF1ab/nsp12594F594CtTctGc11B.1.5760.000907
ORF1ab/nsp12594F594LttCttA11B.1.5960.000087
ORF1ab/nsp12594F594FttCttT11B.1.596.10.009346
ORF1ab/nsp12594F594StTctCc11B.1.617.20.000004
ORF1ab/nsp12594F594LttCttA11B.1.6230.000536
ORF1ab/nsp12594F594FttCttT11B.1.9.50.005682
ORF1ab/nsp12594F594FttCttT11C.110.010638
ORF1ab/nsp12594F594FttCttT11C.360.000911
ORF1ab/nsp12594F594FttCttT11C.370.000116
ORF1ab/nsp12594F594FttCttT11D.20.000075
ORF1ab/nsp12594F594LTtcCtc11D.20.000075
ORF1ab/nsp12594F594StTctCc11D.20.000075
ORF1ab/nsp12594F594FttCttT11P.1.160.000374
ORF1ab/nsp12594F594FttCttT11P.1.20.001156
ORF1ab/nsp12594F594FttCttT11P.20.000187
ORF1ab/nsp12594F594CtTctGc11Q.10.000126
ORF1ab/nsp12594F594CtTctGc11Q.80.000165
ORF1ab/nsp12594F594FttCttT11Q.80.000165
ORF1ab/nsp12594F594delTTC---11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.