CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 583

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12583R583GR4975GnonsynAgaGga18671867115187-15189
ORF1ab/nsp12583R583RR4975RsynagAagG134113290.99105115187-15189
ORF1ab/nsp12583R583RR4975RsynAgaCga1341120.0089485515187-15189
ORF1ab/nsp12583R583KR4975KnonsynaGaaAa8080115187-15189
ORF1ab/nsp12583R583delR4975deldelAGA---4343115187-15189
ORF1ab/nsp12583R583TR4975TnonsynaGaaCa2828115187-15189
ORF1ab/nsp12583R583IR4975InonsynaGaaTa2020115187-15189
ORF1ab/nsp12583R583SR4975SnonsynagAagC16140.87515187-15189
ORF1ab/nsp12583R583SR4975SnonsynagAagT1620.12515187-15189
ORF1ab/nsp12583R583del2R4975del2delAGa--a430.7515187-15189
ORF1ab/nsp12583R583del2R4975del2delAGA--G410.2515187-15189
ORF1ab/nsp12583R583del1R4975del1delagAag-320.66666715187-15189
ORF1ab/nsp12583R583del1R4975del1delAga-ga310.33333315187-15189
ORF1ab/nsp12583R583XR4975XnonsynAgaTga210.515187-15189
ORF1ab/nsp12583R583XR4975XnonsynAGaTAa210.515187-15189

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12583R583GAgaGga18671867All0.000357
ORF1ab/nsp12583R583GAgaGga14271427B.1.214.20.855516
ORF1ab/nsp12583R583RagAagG13291341All0.000254
ORF1ab/nsp12583R583RAgaCga121341All0.000002
ORF1ab/nsp12583R583RagAagG12211232B.1.1.70.001093
ORF1ab/nsp12583R583RAgaCga111232B.1.1.70.00001
ORF1ab/nsp12583R583GAgaGga117117B.1.214.30.835714
ORF1ab/nsp12583R583GAgaGga110110B.1.214.41
ORF1ab/nsp12583R583KaGaaAa8080All0.000015
ORF1ab/nsp12583R583delAGA---4343All0.000008
ORF1ab/nsp12583R583RagAagG3030AY.1030.000186
ORF1ab/nsp12583R583delAGA---3030B.1.1.70.000027
ORF1ab/nsp12583R583GAgaGga2929B.10.000266
ORF1ab/nsp12583R583KaGaaAa2929B.1.1.70.000026
ORF1ab/nsp12583R583TaGaaCa2828All0.000005
ORF1ab/nsp12583R583GAgaGga2222B.1.1.70.00002
ORF1ab/nsp12583R583TaGaaCa2121B.1.3510.000624
ORF1ab/nsp12583R583IaGaaTa2020All0.000004
ORF1ab/nsp12583R583KaGaaAa1919B.1.6230.010193
ORF1ab/nsp12583R583SagAagC1416All0.000003
ORF1ab/nsp12583R583SagAagT216All0
ORF1ab/nsp12583R583GAgaGga1313AY.1030.000081
ORF1ab/nsp12583R583GAgaGga1212B.1.20.000106
ORF1ab/nsp12583R583GAgaGga1212B.1.2100.025586
ORF1ab/nsp12583R583GAgaGga1111AY.430.000049
ORF1ab/nsp12583R583RagAagG1010AY.40.000016
ORF1ab/nsp12583R583SagAagC1010B.1.1.70.000009
ORF1ab/nsp12583R583RagAagG99AY.160.003417
ORF1ab/nsp12583R583GAgaGga99B.1.10.000163
ORF1ab/nsp12583R583GAgaGga99B.1.2210.000639
ORF1ab/nsp12583R583GAgaGga88AY.9.10.00067
ORF1ab/nsp12583R583GAgaGga88B.1.2140.029304
ORF1ab/nsp12583R583GAgaGga77AY.40.000011
ORF1ab/nsp12583R583RagAagG77B.1.1.5190.000278
ORF1ab/nsp12583R583KaGaaAa66B.10.000055
ORF1ab/nsp12583R583RagAagG66B.10.000055
ORF1ab/nsp12583R583GAgaGga66B.1.214.10.12
ORF1ab/nsp12583R583GAgaGga66B.1.617.20.000023
ORF1ab/nsp12583R583GAgaGga66P.10.000095
ORF1ab/nsp12583R583RagAagG55AY.250.00003
ORF1ab/nsp12583R583RagAagG45AY.430.000018
ORF1ab/nsp12583R583RAgaCga15AY.430.000004
ORF1ab/nsp12583R583RagAagG55AY.730.003327
ORF1ab/nsp12583R583IaGaaTa55B.1.1.70.000004
ORF1ab/nsp12583R583KaGaaAa55B.1.4290.000118
ORF1ab/nsp12583R583del2AGa--a34All0.000001
ORF1ab/nsp12583R583del2AGA--G14All0
ORF1ab/nsp12583R583RagAagG44AY.99.20.000369
ORF1ab/nsp12583R583GAgaGga44B.1.1.5190.000159
ORF1ab/nsp12583R583TaGaaCa44B.1.1.70.000004
ORF1ab/nsp12583R583RagAagG44B.1.258.140.003922
ORF1ab/nsp12583R583RagAagG44B.1.617.20.000015
ORF1ab/nsp12583R583del1agAag-23All0
ORF1ab/nsp12583R583del1Aga-ga13All0
ORF1ab/nsp12583R583GAgaGga33AY.360.000445
ORF1ab/nsp12583R583delAGA---33AY.40.000005
ORF1ab/nsp12583R583TaGaaCa33B.1.20.000026
ORF1ab/nsp12583R583GAgaGga33B.1.2430.000209
ORF1ab/nsp12583R583GAgaGga33B.1.3490.002144
ORF1ab/nsp12583R583GAgaGga33B.1.4000.001287
ORF1ab/nsp12583R583GAgaGga33B.1.438.10.000322
ORF1ab/nsp12583R583XAgaTga12All0
ORF1ab/nsp12583R583XAGaTAa12All0
ORF1ab/nsp12583R583IaGaaTa22AY.250.000012
ORF1ab/nsp12583R583GAgaGga22AY.3.10.000171
ORF1ab/nsp12583R583GAgaGga22AY.39.10.000079
ORF1ab/nsp12583R583delAGA---22AY.4.50.000215
ORF1ab/nsp12583R583IaGaaTa22B0.000256
ORF1ab/nsp12583R583SagAagC12B.10.000009
ORF1ab/nsp12583R583XAGaTAa12B.10.000009
ORF1ab/nsp12583R583XAgaTga12B.10.000009
ORF1ab/nsp12583R583SagAagT12B.10.000009
ORF1ab/nsp12583R583RagAagG22B.1.10.000036
ORF1ab/nsp12583R583KaGaaAa22B.1.1.2840.000215
ORF1ab/nsp12583R583IaGaaTa22B.1.20.000018
ORF1ab/nsp12583R583RagAagG22B.1.2580.000133
ORF1ab/nsp12583R583GAgaGga22B.1.258.170.000208
ORF1ab/nsp12583R583GAgaGga22B.1.4270.000101
ORF1ab/nsp12583R583GAgaGga22B.1.4590.008163
ORF1ab/nsp12583R583RagAagG22B.1.5260.000047
ORF1ab/nsp12583R583KaGaaAa22B.1.617.10.000258
ORF1ab/nsp12583R583KaGaaAa22B.1.617.20.000008
ORF1ab/nsp12583R583KaGaaAa22P.10.000032
ORF1ab/nsp12583R583GAgaGga22P.1.140.000096
ORF1ab/nsp12583R583KaGaaAa110.055556
ORF1ab/nsp12583R583KaGaaAa11A.2.5.20.001572
ORF1ab/nsp12583R583del1agAag-11AD.20.000219
ORF1ab/nsp12583R583KaGaaAa11AY.120.10.000321
ORF1ab/nsp12583R583RagAagG11AY.140.000088
ORF1ab/nsp12583R583RagAagG11AY.200.000039
ORF1ab/nsp12583R583GAgaGga11AY.200.000039
ORF1ab/nsp12583R583IaGaaTa11AY.220.002092
ORF1ab/nsp12583R583RagAagG11AY.230.00007
ORF1ab/nsp12583R583GAgaGga11AY.23.10.000417
ORF1ab/nsp12583R583KaGaaAa11AY.250.000006
ORF1ab/nsp12583R583RagAagG11AY.260.000028
ORF1ab/nsp12583R583GAgaGga11AY.260.000028
ORF1ab/nsp12583R583GAgaGga11AY.270.000065
ORF1ab/nsp12583R583RagAagG11AY.290.000016
ORF1ab/nsp12583R583GAgaGga11AY.390.000025
ORF1ab/nsp12583R583SagAagC11AY.40.000002
ORF1ab/nsp12583R583IaGaaTa11AY.40.000002
ORF1ab/nsp12583R583GAgaGga11AY.4.40.000409
ORF1ab/nsp12583R583delAGA---11AY.430.000004
ORF1ab/nsp12583R583del2AGa--a11AY.440.000006
ORF1ab/nsp12583R583KaGaaAa11AY.440.000006
ORF1ab/nsp12583R583RagAagG11AY.440.000006
ORF1ab/nsp12583R583KaGaaAa11AY.470.000031
ORF1ab/nsp12583R583KaGaaAa11AY.50.000021
ORF1ab/nsp12583R583RagAagG11AY.50.000021
ORF1ab/nsp12583R583RagAagG11AY.540.000095
ORF1ab/nsp12583R583GAgaGga11AY.590.00053
ORF1ab/nsp12583R583IaGaaTa11AY.7.10.000113
ORF1ab/nsp12583R583GAgaGga11AY.750.000056
ORF1ab/nsp12583R583RagAagG11AY.850.000427
ORF1ab/nsp12583R583GAgaGga11AY.9.20.000037
ORF1ab/nsp12583R583RagAagG11AY.920.000287
ORF1ab/nsp12583R583del2AGa--a11B0.000128
ORF1ab/nsp12583R583IaGaaTa11B.10.000009
ORF1ab/nsp12583R583delAGA---11B.1.10.000018
ORF1ab/nsp12583R583delAGA---11B.1.1.1390.022727
ORF1ab/nsp12583R583SagAagC11B.1.1.2170.003636
ORF1ab/nsp12583R583SagAagT11B.1.1.2220.000204
ORF1ab/nsp12583R583GAgaGga11B.1.1.4160.000905
ORF1ab/nsp12583R583GAgaGga11B.1.1.4340.000349
ORF1ab/nsp12583R583KaGaaAa11B.1.1.5190.00004
ORF1ab/nsp12583R583GAgaGga11B.1.1.5280.004808
ORF1ab/nsp12583R583del1Aga-ga11B.1.1.70.000001
ORF1ab/nsp12583R583GAgaGga11B.1.1420.002899
ORF1ab/nsp12583R583KaGaaAa11B.1.1600.000031
ORF1ab/nsp12583R583RagAagG11B.1.1600.000031
ORF1ab/nsp12583R583delAGA---11B.1.1600.000031
ORF1ab/nsp12583R583delAGA---11B.1.160.230.004831
ORF1ab/nsp12583R583IaGaaTa11B.1.1770.000013
ORF1ab/nsp12583R583delAGA---11B.1.1770.000013
ORF1ab/nsp12583R583GAgaGga11B.1.1770.000013
ORF1ab/nsp12583R583KaGaaAa11B.1.177.150.000631
ORF1ab/nsp12583R583delAGA---11B.1.177.540.000606
ORF1ab/nsp12583R583delAGA---11B.1.177.600.000218
ORF1ab/nsp12583R583del1agAag-11B.1.177.810.000189
ORF1ab/nsp12583R583GAgaGga11B.1.1790.003759
ORF1ab/nsp12583R583del2AGa--a11B.1.20.000009
ORF1ab/nsp12583R583RagAagG11B.1.20.000009
ORF1ab/nsp12583R583IaGaaTa11B.1.2210.000071
ORF1ab/nsp12583R583SagAagC11B.1.2310.032258
ORF1ab/nsp12583R583RagAagG11B.1.2430.00007
ORF1ab/nsp12583R583GAgaGga11B.1.258.110.000396
ORF1ab/nsp12583R583KaGaaAa11B.1.258.170.000104
ORF1ab/nsp12583R583GAgaGga11B.1.258.90.005
ORF1ab/nsp12583R583GAgaGga11B.1.3510.00003
ORF1ab/nsp12583R583KaGaaAa11B.1.362.20.004717
ORF1ab/nsp12583R583GAgaGga11B.1.4620.007246
ORF1ab/nsp12583R583GAgaGga11B.1.5260.000024
ORF1ab/nsp12583R583GAgaGga11B.1.5610.000397
ORF1ab/nsp12583R583del2AGA--G11B.1.5960.000087
ORF1ab/nsp12583R583GAgaGga11B.1.617.10.000129
ORF1ab/nsp12583R583IaGaaTa11B.1.617.20.000004
ORF1ab/nsp12583R583GAgaGga11B.30.000831
ORF1ab/nsp12583R583KaGaaAa11C.160.00106
ORF1ab/nsp12583R583GAgaGga11C.370.000116
ORF1ab/nsp12583R583IaGaaTa11D.20.000075
ORF1ab/nsp12583R583IaGaaTa11P.10.000016
ORF1ab/nsp12583R583RagAagG11S.10.00495

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.