CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 558 & Codon = gcA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12558A558AA4950AsyngcTgcA23112620.11337115112-15114

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12558A558AgcTgcA2622311All0.00005
ORF1ab/nsp12558A558AgcTgcA180194B.1.1.70.000161
ORF1ab/nsp12558A558AgcTgcA266AY.40.000003
ORF1ab/nsp12558A558AgcTgcA5252AZ.10.0451
ORF1ab/nsp12558A558AgcTgcA228B.1.617.20.000008
ORF1ab/nsp12558A558AgcTgcA120B.1.10.000018
ORF1ab/nsp12558A558AgcTgcA215B.1.20.000018
ORF1ab/nsp12558A558AgcTgcA89B.1.5250.000905
ORF1ab/nsp12558A558AgcTgcA28B.10.000018
ORF1ab/nsp12558A558AgcTgcA23AY.470.000062
ORF1ab/nsp12558A558AgcTgcA12AY.5.30.000337
ORF1ab/nsp12558A558AgcTgcA22AY.99.20.000184
ORF1ab/nsp12558A558AgcTgcA22B.1.5960.000174
ORF1ab/nsp12558A558AgcTgcA11AY.160.00038
ORF1ab/nsp12558A558AgcTgcA11B0.000128
ORF1ab/nsp12558A558AgcTgcA11B.1.4160.001269
ORF1ab/nsp12558A558AgcTgcA11B.1.4620.007246
ORF1ab/nsp12558A558AgcTgcA11B.1.6360.006711
ORF1ab/nsp12558A558AgcTgcA11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.