CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 525

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12525D525DD4917DsyngaTgaC663663115013-15015
ORF1ab/nsp12525D525ND4917NnonsynGatAat2292260.986915013-15015
ORF1ab/nsp12525D525ND4917NnonsynGaTAaC22930.013100415013-15015
ORF1ab/nsp12525D525delD4917deldelGAT---4343115013-15015
ORF1ab/nsp12525D525YD4917YnonsynGatTat1414115013-15015
ORF1ab/nsp12525D525ED4917EnonsyngaTgaA1280.66666715013-15015
ORF1ab/nsp12525D525ED4917EnonsyngaTgaG1240.33333315013-15015
ORF1ab/nsp12525D525VD4917VnonsyngAtgTt860.7515013-15015
ORF1ab/nsp12525D525VD4917VnonsyngATgTA820.2515013-15015
ORF1ab/nsp12525D525AD4917AnonsyngAtgCt640.66666715013-15015
ORF1ab/nsp12525D525AD4917AnonsyngATgCA620.33333315013-15015
ORF1ab/nsp12525D525HD4917HnonsynGatCat530.615013-15015
ORF1ab/nsp12525D525HD4917HnonsynGaTCaC520.415013-15015
ORF1ab/nsp12525D525GD4917GnonsyngAtgGt44115013-15015
ORF1ab/nsp12525D525del1D4917del1delGat-at11115013-15015
ORF1ab/nsp12525D525CD4917CnonsynGAtTGt11115013-15015
ORF1ab/nsp12525D525ID4917InonsynGATATC11115013-15015

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12525D525DgaTgaC663663All0.000127
ORF1ab/nsp12525D525DgaTgaC337337B.1.1.70.000302
ORF1ab/nsp12525D525NGatAat226229All0.000043
ORF1ab/nsp12525D525NGaTAaC3229All0.000001
ORF1ab/nsp12525D525NGatAat167167AY.40.00026
ORF1ab/nsp12525D525DgaTgaC9595B.1.1770.001251
ORF1ab/nsp12525D525DgaTgaC5757C.40.57
ORF1ab/nsp12525D525delGAT---4343All0.000008
ORF1ab/nsp12525D525DgaTgaC2424B.1.1.4350.827586
ORF1ab/nsp12525D525NGatAat2222AY.250.000132
ORF1ab/nsp12525D525DgaTgaC1515AY.1170.001268
ORF1ab/nsp12525D525YGatTat1414All0.000003
ORF1ab/nsp12525D525NGatAat1313AY.9.20.000477
ORF1ab/nsp12525D525EgaTgaA812All0.000002
ORF1ab/nsp12525D525EgaTgaG412All0.000001
ORF1ab/nsp12525D525DgaTgaC1212B.1.1.2800.037037
ORF1ab/nsp12525D525DgaTgaC1111B.1.2390.013431
ORF1ab/nsp12525D525delGAT---1010B.1.1.70.000009
ORF1ab/nsp12525D525DgaTgaC1010B.1.617.20.000038
ORF1ab/nsp12525D525DgaTgaC99AY.440.000055
ORF1ab/nsp12525D525VgAtgTt68All0.000001
ORF1ab/nsp12525D525VgATgTA28All0
ORF1ab/nsp12525D525DgaTgaC88AY.250.000048
ORF1ab/nsp12525D525DgaTgaC77AY.1030.000043
ORF1ab/nsp12525D525DgaTgaC77AY.40.000011
ORF1ab/nsp12525D525DgaTgaC77B.10.000064
ORF1ab/nsp12525D525DgaTgaC77B.1.5680.007778
ORF1ab/nsp12525D525AgAtgCt46All0.000001
ORF1ab/nsp12525D525AgATgCA26All0
ORF1ab/nsp12525D525VgAtgTt350.166667
ORF1ab/nsp12525D525VgATgTA250.111111
ORF1ab/nsp12525D525HGatCat35All0.000001
ORF1ab/nsp12525D525HGaTCaC25All0
ORF1ab/nsp12525D525DgaTgaC55AY.390.000124
ORF1ab/nsp12525D525DgaTgaC55AY.430.000022
ORF1ab/nsp12525D525EgaTgaA45AY.440.000024
ORF1ab/nsp12525D525EgaTgaG15AY.440.000006
ORF1ab/nsp12525D525NGatAat45B.1.617.20.000015
ORF1ab/nsp12525D525NGaTAaC15B.1.617.20.000004
ORF1ab/nsp12525D525delGAT---440.222222
ORF1ab/nsp12525D525AgATgCA240.111111
ORF1ab/nsp12525D525AgAtgCt240.111111
ORF1ab/nsp12525D525GgAtgGt44All0.000001
ORF1ab/nsp12525D525NGatAat34AY.440.000018
ORF1ab/nsp12525D525NGaTAaC14AY.440.000006
ORF1ab/nsp12525D525DgaTgaC44B.1.10.000073
ORF1ab/nsp12525D525DgaTgaC44B.1.1.10.001307
ORF1ab/nsp12525D525NGatAat33AY.1030.000019
ORF1ab/nsp12525D525delGAT---33AY.1070.001398
ORF1ab/nsp12525D525DgaTgaC33AY.290.000047
ORF1ab/nsp12525D525YGatTat33B.10.000027
ORF1ab/nsp12525D525YGatTat33B.1.10.000054
ORF1ab/nsp12525D525delGAT---33B.1.10.000054
ORF1ab/nsp12525D525DgaTgaC33B.1.4270.000151
ORF1ab/nsp12525D525DgaTgaC33B.1.6370.000219
ORF1ab/nsp12525D525EgaTgaA220.111111
ORF1ab/nsp12525D525DgaTgaC220.111111
ORF1ab/nsp12525D525NGatAat22AY.1000.000092
ORF1ab/nsp12525D525NGatAat22AY.390.000049
ORF1ab/nsp12525D525delGAT---22AY.40.000003
ORF1ab/nsp12525D525delGAT---22AY.430.000009
ORF1ab/nsp12525D525DgaTgaC22AZ.60.016807
ORF1ab/nsp12525D525DgaTgaC22B.1.1.1700.002494
ORF1ab/nsp12525D525DgaTgaC22B.1.2210.000142
ORF1ab/nsp12525D525DgaTgaC22B.1.3510.000059
ORF1ab/nsp12525D525DgaTgaC22B.1.36.10.002281
ORF1ab/nsp12525D525DgaTgaC22C.370.000232
ORF1ab/nsp12525D525DgaTgaC22P.10.000032
ORF1ab/nsp12525D525delGAT---22P.10.000032
ORF1ab/nsp12525D525YGatTat11A0.000387
ORF1ab/nsp12525D525VgAtgTt11A.2.40.003367
ORF1ab/nsp12525D525DgaTgaC11AD.20.000219
ORF1ab/nsp12525D525del1Gat-at11All0
ORF1ab/nsp12525D525CGAtTGt11All0
ORF1ab/nsp12525D525IGATATC11All0
ORF1ab/nsp12525D525DgaTgaC11AY.1000.000046
ORF1ab/nsp12525D525NGatAat11AY.1020.000027
ORF1ab/nsp12525D525DgaTgaC11AY.1100.000113
ORF1ab/nsp12525D525NGatAat11AY.1170.000085
ORF1ab/nsp12525D525DgaTgaC11AY.1190.000035
ORF1ab/nsp12525D525delGAT---11AY.250.000006
ORF1ab/nsp12525D525HGatCat11AY.250.000006
ORF1ab/nsp12525D525NGatAat11AY.290.000016
ORF1ab/nsp12525D525NGatAat11AY.30.00001
ORF1ab/nsp12525D525GgAtgGt11AY.30.00001
ORF1ab/nsp12525D525GgAtgGt11AY.390.000025
ORF1ab/nsp12525D525DgaTgaC11AY.39.10.00004
ORF1ab/nsp12525D525GgAtgGt11AY.40.000002
ORF1ab/nsp12525D525YGatTat11AY.4.40.000409
ORF1ab/nsp12525D525AgAtgCt11AY.420.00004
ORF1ab/nsp12525D525delGAT---11AY.420.00004
ORF1ab/nsp12525D525HGaTCaC11AY.430.000004
ORF1ab/nsp12525D525delGAT---11AY.440.000006
ORF1ab/nsp12525D525VgAtgTt11AY.440.000006
ORF1ab/nsp12525D525NGatAat11AY.50.000021
ORF1ab/nsp12525D525AgAtgCt11AY.510.000909
ORF1ab/nsp12525D525EgaTgaA11AY.540.000095
ORF1ab/nsp12525D525delGAT---11AY.650.000533
ORF1ab/nsp12525D525delGAT---11AY.670.000464
ORF1ab/nsp12525D525DgaTgaC11AY.750.000056
ORF1ab/nsp12525D525CGAtTGt11AY.750.000056
ORF1ab/nsp12525D525DgaTgaC11AY.75.10.00018
ORF1ab/nsp12525D525HGaTCaC11AY.840.000437
ORF1ab/nsp12525D525NGatAat11AY.850.000427
ORF1ab/nsp12525D525delGAT---11AY.990.001049
ORF1ab/nsp12525D525NGatAat11B.10.000009
ORF1ab/nsp12525D525NGatAat11B.1.10.000018
ORF1ab/nsp12525D525HGatCat11B.1.1.1980.001468
ORF1ab/nsp12525D525delGAT---11B.1.1.3060.000438
ORF1ab/nsp12525D525del1Gat-at11B.1.1.3060.000438
ORF1ab/nsp12525D525delGAT---11B.1.1.3110.000358
ORF1ab/nsp12525D525EgaTgaG11B.1.1.3690.000446
ORF1ab/nsp12525D525DgaTgaC11B.1.1.3720.000689
ORF1ab/nsp12525D525YGatTat11B.1.1.70.000001
ORF1ab/nsp12525D525delGAT---11B.1.1.700.000341
ORF1ab/nsp12525D525delGAT---11B.1.160.230.004831
ORF1ab/nsp12525D525delGAT---11B.1.160.70.002079
ORF1ab/nsp12525D525DgaTgaC11B.1.160.90.007194
ORF1ab/nsp12525D525DgaTgaC11B.1.177.480.003125
ORF1ab/nsp12525D525EgaTgaG11B.1.177.480.003125
ORF1ab/nsp12525D525delGAT---11B.1.177.600.000218
ORF1ab/nsp12525D525delGAT---11B.1.177.680.015152
ORF1ab/nsp12525D525delGAT---11B.1.177.760.002494
ORF1ab/nsp12525D525delGAT---11B.1.177.870.000728
ORF1ab/nsp12525D525DgaTgaC11B.1.20.000009
ORF1ab/nsp12525D525DgaTgaC11B.1.2360.002053
ORF1ab/nsp12525D525YGatTat11B.1.3510.00003
ORF1ab/nsp12525D525DgaTgaC11B.1.3670.000792
ORF1ab/nsp12525D525VgAtgTt11B.1.4160.001269
ORF1ab/nsp12525D525DgaTgaC11B.1.4290.000024
ORF1ab/nsp12525D525YGatTat11B.1.4290.000024
ORF1ab/nsp12525D525NGatAat11B.1.4290.000024
ORF1ab/nsp12525D525NGatAat11B.1.466.20.000391
ORF1ab/nsp12525D525EgaTgaG11B.1.5250.000113
ORF1ab/nsp12525D525HGatCat11B.1.5610.000397
ORF1ab/nsp12525D525NGaTAaC11B.1.5680.001111
ORF1ab/nsp12525D525GgAtgGt11B.1.5950.000261
ORF1ab/nsp12525D525IGATATC11B.1.617.20.000004
ORF1ab/nsp12525D525YGatTat11B.1.617.20.000004
ORF1ab/nsp12525D525EgaTgaA11B.6.60.000889
ORF1ab/nsp12525D525YGatTat11D.20.000075
ORF1ab/nsp12525D525YGatTat11P.10.000016
ORF1ab/nsp12525D525delGAT---11P.1.40.000977
ORF1ab/nsp12525D525delGAT---11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.