CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 436 & Codon = gTa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12436E436VE4828VnonsyngAagTa22210.95454514746-14748

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12436E436VgAagTa2122All0.000004
ORF1ab/nsp12436E436VgAagTa56B.1.1.70.000004
ORF1ab/nsp12436E436VgAagTa44B.1.20.000035
ORF1ab/nsp12436E436VgAagTa22B.1.1.3010.002358
ORF1ab/nsp12436E436VgAagTa110.055556
ORF1ab/nsp12436E436VgAagTa11B.1.1770.000013
ORF1ab/nsp12436E436VgAagTa11B.1.177.70.000165
ORF1ab/nsp12436E436VgAagTa11B.1.177.860.000183
ORF1ab/nsp12436E436VgAagTa11B.1.2430.00007
ORF1ab/nsp12436E436VgAagTa11B.1.466.20.000391
ORF1ab/nsp12436E436VgAagTa11B.1.617.20.000004
ORF1ab/nsp12436E436VgAagTa11B.400.000364
ORF1ab/nsp12436E436VgAagTa11B.610.005747
ORF1ab/nsp12436E436VgAagTa11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.