CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 381 & Codon = Tac

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12381H381YH4773YnonsynCacTac111960.86486514581-14583

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12381H381YCacTac96111All0.000018
ORF1ab/nsp12381H381YCacTac1928B.1.1.70.000017
ORF1ab/nsp12381H381YCacTac1313AY.40.00002
ORF1ab/nsp12381H381YCacTac811B.10.000073
ORF1ab/nsp12381H381YCacTac88AY.930.002185
ORF1ab/nsp12381H381YCacTac88B.1.617.20.00003
ORF1ab/nsp12381H381YCacTac55AY.250.00003
ORF1ab/nsp12381H381YCacTac44AY.30.00004
ORF1ab/nsp12381H381YCacTac33AY.1190.000106
ORF1ab/nsp12381H381YCacTac33B.1.1600.000094
ORF1ab/nsp12381H381YCacTac23B.1.20.000018
ORF1ab/nsp12381H381YCacTac22AY.290.000032
ORF1ab/nsp12381H381YCacTac22AY.440.000012
ORF1ab/nsp12381H381YCacTac22AY.980.000158
ORF1ab/nsp12381H381YCacTac22B.1.1770.000026
ORF1ab/nsp12381H381YCacTac12B.1.5250.000113
ORF1ab/nsp12381H381YCacTac12B.1.5760.000907
ORF1ab/nsp12381H381YCacTac11AY.1030.000006
ORF1ab/nsp12381H381YCacTac11AY.1160.000287
ORF1ab/nsp12381H381YCacTac11AY.1180.000063
ORF1ab/nsp12381H381YCacTac11AY.330.000067
ORF1ab/nsp12381H381YCacTac11AY.430.000004
ORF1ab/nsp12381H381YCacTac11AY.46.60.000072
ORF1ab/nsp12381H381YCacTac11B.1.177.520.001757
ORF1ab/nsp12381H381YCacTac11B.1.2410.000812
ORF1ab/nsp12381H381YCacTac11B.1.2580.000067
ORF1ab/nsp12381H381YCacTac11B.1.2650.001271
ORF1ab/nsp12381H381YCacTac11B.1.36.360.000602
ORF1ab/nsp12381H381YCacTac11B.1.4950.009091
ORF1ab/nsp12381H381YCacTac11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.