CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 350 & Codon = gaA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12350E350EE4742EsyngaGgaA550550114488-14490

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12350E350EgaGgaA550550All0.000105
ORF1ab/nsp12350E350EgaGgaA231231B.1.1.70.000207
ORF1ab/nsp12350E350EgaGgaA208208B.1.351.20.062935
ORF1ab/nsp12350E350EgaGgaA2424B.1.20.000211
ORF1ab/nsp12350E350EgaGgaA1818AY.40.000028
ORF1ab/nsp12350E350EgaGgaA77AY.430.000031
ORF1ab/nsp12350E350EgaGgaA66AY.250.000036
ORF1ab/nsp12350E350EgaGgaA66AY.640.003571
ORF1ab/nsp12350E350EgaGgaA55B.1.1.1920.011547
ORF1ab/nsp12350E350EgaGgaA44B.1.617.20.000015
ORF1ab/nsp12350E350EgaGgaA33AY.290.000047
ORF1ab/nsp12350E350EgaGgaA33AY.440.000018
ORF1ab/nsp12350E350EgaGgaA33B.1.1.2220.000612
ORF1ab/nsp12350E350EgaGgaA22AY.1060.00067
ORF1ab/nsp12350E350EgaGgaA22AY.1190.000071
ORF1ab/nsp12350E350EgaGgaA22AY.120.10.000642
ORF1ab/nsp12350E350EgaGgaA22B.10.000018
ORF1ab/nsp12350E350EgaGgaA22B.1.3510.000059
ORF1ab/nsp12350E350EgaGgaA11A.10.000282
ORF1ab/nsp12350E350EgaGgaA11A.20.000662
ORF1ab/nsp12350E350EgaGgaA11AY.1030.000006
ORF1ab/nsp12350E350EgaGgaA11AY.1140.000231
ORF1ab/nsp12350E350EgaGgaA11AY.116.10.000311
ORF1ab/nsp12350E350EgaGgaA11AY.1200.000037
ORF1ab/nsp12350E350EgaGgaA11AY.200.000039
ORF1ab/nsp12350E350EgaGgaA11AY.420.00004
ORF1ab/nsp12350E350EgaGgaA11AY.450.000122
ORF1ab/nsp12350E350EgaGgaA11AY.5.20.002463
ORF1ab/nsp12350E350EgaGgaA11AY.590.00053
ORF1ab/nsp12350E350EgaGgaA11AY.750.000056
ORF1ab/nsp12350E350EgaGgaA11AY.98.10.000048
ORF1ab/nsp12350E350EgaGgaA11B0.000128
ORF1ab/nsp12350E350EgaGgaA11B.1.1.2940.001266
ORF1ab/nsp12350E350EgaGgaA11B.1.1600.000031
ORF1ab/nsp12350E350EgaGgaA11B.1.160.160.000929
ORF1ab/nsp12350E350EgaGgaA11B.1.177.70.000165
ORF1ab/nsp12350E350EgaGgaA11B.1.177.730.000566
ORF1ab/nsp12350E350EgaGgaA11B.1.2800.007143
ORF1ab/nsp12350E350EgaGgaA11B.1.5260.000024
ORF1ab/nsp12350E350EgaGgaA11B.1.6210.000089

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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