CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 350

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12350E350DE4742DnonsyngaGgaT7097010.98871614488-14490
ORF1ab/nsp12350E350DE4742DnonsyngaGgaC70980.011283514488-14490
ORF1ab/nsp12350E350EE4742EsyngaGgaA550550114488-14490
ORF1ab/nsp12350E350GE4742GnonsyngAggGg320320114488-14490
ORF1ab/nsp12350E350delE4742deldelGAG---199199114488-14490
ORF1ab/nsp12350E350XE4742XnonsynGagTag55530.96363614488-14490
ORF1ab/nsp12350E350XE4742XnonsynGAGTGA5520.036363614488-14490
ORF1ab/nsp12350E350AE4742AnonsyngAggCg44420.95454514488-14490
ORF1ab/nsp12350E350AE4742AnonsyngAGgCC4420.045454514488-14490
ORF1ab/nsp12350E350KE4742KnonsynGagAag980.88888914488-14490
ORF1ab/nsp12350E350KE4742KnonsynGaGAaA910.11111114488-14490
ORF1ab/nsp12350E350VE4742VnonsyngAggTg870.87514488-14490
ORF1ab/nsp12350E350VE4742VnonsyngAGgTA810.12514488-14490
ORF1ab/nsp12350E350del2E4742del2delgAGg--530.614488-14490
ORF1ab/nsp12350E350del2E4742del2delGAg--g510.214488-14490
ORF1ab/nsp12350E350del2E4742del2delGAGA--510.214488-14490
ORF1ab/nsp12350E350LE4742LnonsynGAGCTC33114488-14490
ORF1ab/nsp12350E350QE4742QnonsynGagCag33114488-14490
ORF1ab/nsp12350E350NE4742NnonsynGaGAaT320.66666714488-14490
ORF1ab/nsp12350E350NE4742NnonsynGaGAaC310.33333314488-14490
ORF1ab/nsp12350E350del1E4742del1delgaGga-310.33333314488-14490
ORF1ab/nsp12350E350del1E4742del1delGaG-aA310.33333314488-14490
ORF1ab/nsp12350E350del1E4742del1delGAGAG-310.33333314488-14490
ORF1ab/nsp12350E350HE4742HnonsynGaGCaT22114488-14490
ORF1ab/nsp12350E350SE4742SnonsynGAGAGC210.514488-14490
ORF1ab/nsp12350E350SE4742SnonsynGAgTCg210.514488-14490
ORF1ab/nsp12350E350ME4742MnonsynGAgATg11114488-14490
ORF1ab/nsp12350E350RE4742RnonsynGAGAGA11114488-14490
ORF1ab/nsp12350E350PE4742PnonsynGAGCCA11114488-14490

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12350E350DgaGgaT701709All0.000134
ORF1ab/nsp12350E350DgaGgaC8709All0.000002
ORF1ab/nsp12350E350EgaGgaA550550All0.000105
ORF1ab/nsp12350E350GgAggGg320320All0.000061
ORF1ab/nsp12350E350EgaGgaA231231B.1.1.70.000207
ORF1ab/nsp12350E350EgaGgaA208208B.1.351.20.062935
ORF1ab/nsp12350E350delGAG---199199All0.000038
ORF1ab/nsp12350E350DgaGgaT156156B.1.20.001374
ORF1ab/nsp12350E350DgaGgaT140140B.1.4290.003294
ORF1ab/nsp12350E350DgaGgaT116117B.1.1.70.000104
ORF1ab/nsp12350E350DgaGgaC1117B.1.1.70.000001
ORF1ab/nsp12350E350GgAggGg9191AY.40.000142
ORF1ab/nsp12350E350delGAG---7878B.1.1.70.00007
ORF1ab/nsp12350E350GgAggGg7171B.1.5260.001669
ORF1ab/nsp12350E350DgaGgaT6060B.1.4270.00303
ORF1ab/nsp12350E350GgAggGg5959B.1.5631
ORF1ab/nsp12350E350XGagTag5355All0.00001
ORF1ab/nsp12350E350XGAGTGA255All0
ORF1ab/nsp12350E350AgAggCg4244All0.000008
ORF1ab/nsp12350E350AgAGgCC244All0
ORF1ab/nsp12350E350GgAggGg4040AY.620.017429
ORF1ab/nsp12350E350XGagTag3535D.20.002626
ORF1ab/nsp12350E350DgaGgaT2829B.10.000256
ORF1ab/nsp12350E350DgaGgaC129B.10.000009
ORF1ab/nsp12350E350DgaGgaT2727B.1.258.240.290323
ORF1ab/nsp12350E350EgaGgaA2424B.1.20.000211
ORF1ab/nsp12350E350DgaGgaT2424B.1.2430.00167
ORF1ab/nsp12350E350AgAggCg2222AY.40.000034
ORF1ab/nsp12350E350DgaGgaT2020B.1.5960.001743
ORF1ab/nsp12350E350EgaGgaA1818AY.40.000028
ORF1ab/nsp12350E350DgaGgaT1616B.1.1.5190.000635
ORF1ab/nsp12350E350delGAG---1111B.10.000101
ORF1ab/nsp12350E350delGAG---1111B.1.617.20.000041
ORF1ab/nsp12350E350KGagAag89All0.000002
ORF1ab/nsp12350E350KGaGAaA19All0
ORF1ab/nsp12350E350delGAG---99AY.40.000014
ORF1ab/nsp12350E350GgAggGg99B.10.000082
ORF1ab/nsp12350E350GgAggGg99B.1.20.000079
ORF1ab/nsp12350E350DgaGgaT99B.1.2340.001187
ORF1ab/nsp12350E350VgAggTg78All0.000001
ORF1ab/nsp12350E350VgAGgTA18All0
ORF1ab/nsp12350E350DgaGgaT88AY.4.2.10.001192
ORF1ab/nsp12350E350AgAggCg88B.1.1.70.000007
ORF1ab/nsp12350E350GgAggGg88B.1.617.20.00003
ORF1ab/nsp12350E350EgaGgaA77AY.430.000031
ORF1ab/nsp12350E350GgAggGg77B.1.1.70.000006
ORF1ab/nsp12350E350DgaGgaT77B.1.5510.009032
ORF1ab/nsp12350E350DgaGgaT77B.1.5610.002779
ORF1ab/nsp12350E350EgaGgaA66AY.250.000036
ORF1ab/nsp12350E350EgaGgaA66AY.640.003571
ORF1ab/nsp12350E350DgaGgaT66B.1.3110.001647
ORF1ab/nsp12350E350DgaGgaT66B.1.4040.007812
ORF1ab/nsp12350E350DgaGgaT66B.1.6090.002876
ORF1ab/nsp12350E350del2gAGg--35All0.000001
ORF1ab/nsp12350E350del2GAg--g15All0
ORF1ab/nsp12350E350del2GAGA--15All0
ORF1ab/nsp12350E350GgAggGg55AY.250.00003
ORF1ab/nsp12350E350EgaGgaA55B.1.1.1920.011547
ORF1ab/nsp12350E350delGAG---44AY.1020.000106
ORF1ab/nsp12350E350delGAG---44AY.1080.00441
ORF1ab/nsp12350E350DgaGgaT44AY.540.000381
ORF1ab/nsp12350E350DgaGgaT44B.1.1.2220.000816
ORF1ab/nsp12350E350DgaGgaT44B.1.1.3160.0037
ORF1ab/nsp12350E350XGagTag34B.1.1.70.000003
ORF1ab/nsp12350E350XGAGTGA14B.1.1.70.000001
ORF1ab/nsp12350E350DgaGgaT44B.1.4000.001716
ORF1ab/nsp12350E350EgaGgaA44B.1.617.20.000015
ORF1ab/nsp12350E350GgAggGg44P.10.000063
ORF1ab/nsp12350E350DgaGgaT44P.20.000747
ORF1ab/nsp12350E350LGAGCTC33All0.000001
ORF1ab/nsp12350E350QGagCag33All0.000001
ORF1ab/nsp12350E350NGaGAaT23All0
ORF1ab/nsp12350E350NGaGAaC13All0
ORF1ab/nsp12350E350del1GAGAG-13All0
ORF1ab/nsp12350E350del1GaG-aA13All0
ORF1ab/nsp12350E350del1gaGga-13All0
ORF1ab/nsp12350E350EgaGgaA33AY.290.000047
ORF1ab/nsp12350E350DgaGgaT23AY.40.000003
ORF1ab/nsp12350E350DgaGgaC13AY.40.000002
ORF1ab/nsp12350E350delGAG---33AY.4.50.000322
ORF1ab/nsp12350E350delGAG---33AY.430.000013
ORF1ab/nsp12350E350EgaGgaA33AY.440.000018
ORF1ab/nsp12350E350delGAG---33AY.9.20.00011
ORF1ab/nsp12350E350XGagTag33B.10.000027
ORF1ab/nsp12350E350delGAG---33B.1.10.000054
ORF1ab/nsp12350E350EgaGgaA33B.1.1.2220.000612
ORF1ab/nsp12350E350delGAG---33B.1.20.000026
ORF1ab/nsp12350E350delGAG---33B.1.3670.002377
ORF1ab/nsp12350E350delGAG---33B.1.5250.000339
ORF1ab/nsp12350E350DgaGgaT33B.1.5260.000071
ORF1ab/nsp12350E350DgaGgaT33B.1.5950.000783
ORF1ab/nsp12350E350XGagTag33B.1.617.20.000011
ORF1ab/nsp12350E350GgAggGg33R.10.00027
ORF1ab/nsp12350E350DgaGgaC220.111111
ORF1ab/nsp12350E350AgAGgCC220.111111
ORF1ab/nsp12350E350HGaGCaT220.111111
ORF1ab/nsp12350E350HGaGCaT22All0
ORF1ab/nsp12350E350SGAgTCg12All0
ORF1ab/nsp12350E350SGAGAGC12All0
ORF1ab/nsp12350E350EgaGgaA22AY.1060.00067
ORF1ab/nsp12350E350EgaGgaA22AY.1190.000071
ORF1ab/nsp12350E350EgaGgaA22AY.120.10.000642
ORF1ab/nsp12350E350AgAggCg22AY.39.10.000079
ORF1ab/nsp12350E350GgAggGg22AY.4.20.000043
ORF1ab/nsp12350E350delGAG---22AY.750.000112
ORF1ab/nsp12350E350delGAG---22AY.990.002099
ORF1ab/nsp12350E350EgaGgaA22B.10.000018
ORF1ab/nsp12350E350GgAggGg22B.1.10.000036
ORF1ab/nsp12350E350DgaGgaT22B.1.1.4320.002532
ORF1ab/nsp12350E350KGagAag22B.1.1.70.000002
ORF1ab/nsp12350E350VgAggTg22B.1.1.70.000002
ORF1ab/nsp12350E350del2gAGg--22B.1.1.70.000002
ORF1ab/nsp12350E350delGAG---22B.1.177.540.001213
ORF1ab/nsp12350E350DgaGgaT22B.1.2390.002442
ORF1ab/nsp12350E350DgaGgaT22B.1.243.10.044444
ORF1ab/nsp12350E350delGAG---22B.1.3510.000059
ORF1ab/nsp12350E350EgaGgaA22B.1.3510.000059
ORF1ab/nsp12350E350DgaGgaT22B.1.3510.000059
ORF1ab/nsp12350E350AgAggCg22B.1.4330.00639
ORF1ab/nsp12350E350DgaGgaT22B.1.5820.000981
ORF1ab/nsp12350E350delGAG---22B.1.617.10.000258
ORF1ab/nsp12350E350DgaGgaT22D.20.00015
ORF1ab/nsp12350E350DgaGgaT22R.10.00018
ORF1ab/nsp12350E350GgAggGg110.055556
ORF1ab/nsp12350E350XGagTag110.055556
ORF1ab/nsp12350E350delGAG---11A0.000387
ORF1ab/nsp12350E350EgaGgaA11A.10.000282
ORF1ab/nsp12350E350EgaGgaA11A.20.000662
ORF1ab/nsp12350E350XGagTag11A.20.000662
ORF1ab/nsp12350E350DgaGgaT11A.2.50.000499
ORF1ab/nsp12350E350delGAG---11AE.20.058824
ORF1ab/nsp12350E350MGAgATg11All0
ORF1ab/nsp12350E350RGAGAGA11All0
ORF1ab/nsp12350E350PGAGCCA11All0
ORF1ab/nsp12350E350DgaGgaT11AY.1000.000046
ORF1ab/nsp12350E350EgaGgaA11AY.1030.000006
ORF1ab/nsp12350E350DgaGgaC11AY.1030.000006
ORF1ab/nsp12350E350delGAG---11AY.1070.000466
ORF1ab/nsp12350E350delGAG---11AY.1110.000183
ORF1ab/nsp12350E350EgaGgaA11AY.1140.000231
ORF1ab/nsp12350E350EgaGgaA11AY.116.10.000311
ORF1ab/nsp12350E350MGAgATg11AY.1190.000035
ORF1ab/nsp12350E350KGagAag11AY.1190.000035
ORF1ab/nsp12350E350EgaGgaA11AY.1200.000037
ORF1ab/nsp12350E350del1GAGAG-11AY.120.10.000321
ORF1ab/nsp12350E350GgAggGg11AY.160.00038
ORF1ab/nsp12350E350delGAG---11AY.190.00114
ORF1ab/nsp12350E350EgaGgaA11AY.200.000039
ORF1ab/nsp12350E350AgAggCg11AY.250.000006
ORF1ab/nsp12350E350delGAG---11AY.260.000028
ORF1ab/nsp12350E350delGAG---11AY.30.00001
ORF1ab/nsp12350E350AgAggCg11AY.30.00001
ORF1ab/nsp12350E350delGAG---11AY.360.000148
ORF1ab/nsp12350E350LGAGCTC11AY.40.000002
ORF1ab/nsp12350E350delGAG---11AY.420.00004
ORF1ab/nsp12350E350EgaGgaA11AY.420.00004
ORF1ab/nsp12350E350KGaGAaA11AY.430.000004
ORF1ab/nsp12350E350XGagTag11AY.440.000006
ORF1ab/nsp12350E350delGAG---11AY.440.000006
ORF1ab/nsp12350E350KGagAag11AY.440.000006
ORF1ab/nsp12350E350del2GAg--g11AY.440.000006
ORF1ab/nsp12350E350del1GaG-aA11AY.440.000006
ORF1ab/nsp12350E350EgaGgaA11AY.450.000122
ORF1ab/nsp12350E350GgAggGg11AY.460.000104
ORF1ab/nsp12350E350GgAggGg11AY.46.40.000165
ORF1ab/nsp12350E350delGAG---11AY.46.60.000072
ORF1ab/nsp12350E350SGAGAGC11AY.46.60.000072
ORF1ab/nsp12350E350DgaGgaT11AY.470.000031
ORF1ab/nsp12350E350delGAG---11AY.50.000021
ORF1ab/nsp12350E350EgaGgaA11AY.5.20.002463
ORF1ab/nsp12350E350delGAG---11AY.5.40.000277
ORF1ab/nsp12350E350EgaGgaA11AY.590.00053
ORF1ab/nsp12350E350delGAG---11AY.620.000436
ORF1ab/nsp12350E350delGAG---11AY.650.000533
ORF1ab/nsp12350E350AgAggCg11AY.670.000464
ORF1ab/nsp12350E350delGAG---11AY.720.001361
ORF1ab/nsp12350E350EgaGgaA11AY.750.000056
ORF1ab/nsp12350E350delGAG---11AY.75.10.00018
ORF1ab/nsp12350E350delGAG---11AY.90.000068
ORF1ab/nsp12350E350EgaGgaA11AY.98.10.000048
ORF1ab/nsp12350E350DgaGgaT11AZ.30.00152
ORF1ab/nsp12350E350delGAG---11AZ.50.003509
ORF1ab/nsp12350E350DgaGgaT11AZ.50.003509
ORF1ab/nsp12350E350DgaGgaT11B0.000128
ORF1ab/nsp12350E350EgaGgaA11B0.000128
ORF1ab/nsp12350E350QGagCag11B.10.000009
ORF1ab/nsp12350E350KGagAag11B.10.000009
ORF1ab/nsp12350E350VgAggTg11B.10.000009
ORF1ab/nsp12350E350DgaGgaT11B.1.10.000018
ORF1ab/nsp12350E350QGagCag11B.1.10.000018
ORF1ab/nsp12350E350KGagAag11B.1.10.000018
ORF1ab/nsp12350E350delGAG---11B.1.1.1390.022727
ORF1ab/nsp12350E350delGAG---11B.1.1.1920.002309
ORF1ab/nsp12350E350VgAggTg11B.1.1.1920.002309
ORF1ab/nsp12350E350DgaGgaT11B.1.1.2070.001182
ORF1ab/nsp12350E350del2gAGg--11B.1.1.2180.007692
ORF1ab/nsp12350E350delGAG---11B.1.1.2210.010101
ORF1ab/nsp12350E350DgaGgaT11B.1.1.2310.003096
ORF1ab/nsp12350E350XGagTag11B.1.1.280.000311
ORF1ab/nsp12350E350delGAG---11B.1.1.2840.000107
ORF1ab/nsp12350E350delGAG---11B.1.1.2880.001916
ORF1ab/nsp12350E350EgaGgaA11B.1.1.2940.001266
ORF1ab/nsp12350E350GgAggGg11B.1.1.3120.001912
ORF1ab/nsp12350E350XGagTag11B.1.1.370.000193
ORF1ab/nsp12350E350delGAG---11B.1.1.370.000193
ORF1ab/nsp12350E350delGAG---11B.1.1.390.00051
ORF1ab/nsp12350E350AgAggCg11B.1.1.4340.000349
ORF1ab/nsp12350E350del2GAGA--11B.1.1.5190.00004
ORF1ab/nsp12350E350PGAGCCA11B.1.1.70.000001
ORF1ab/nsp12350E350SGAgTCg11B.1.1.70.000001
ORF1ab/nsp12350E350QGagCag11B.1.1.70.000001
ORF1ab/nsp12350E350RGAGAGA11B.1.1.70.000001
ORF1ab/nsp12350E350LGAGCTC11B.1.1.70.000001
ORF1ab/nsp12350E350DgaGgaT11B.1.1390.000733
ORF1ab/nsp12350E350VgAggTg11B.1.1600.000031
ORF1ab/nsp12350E350EgaGgaA11B.1.1600.000031
ORF1ab/nsp12350E350EgaGgaA11B.1.160.160.000929
ORF1ab/nsp12350E350delGAG---11B.1.1610.017241
ORF1ab/nsp12350E350delGAG---11B.1.1770.000013
ORF1ab/nsp12350E350DgaGgaT11B.1.1770.000013
ORF1ab/nsp12350E350XGagTag11B.1.1770.000013
ORF1ab/nsp12350E350DgaGgaT11B.1.177.120.000152
ORF1ab/nsp12350E350KGagAag11B.1.177.230.003236
ORF1ab/nsp12350E350delGAG---11B.1.177.40.000211
ORF1ab/nsp12350E350GgAggGg11B.1.177.560.000668
ORF1ab/nsp12350E350delGAG---11B.1.177.570.000281
ORF1ab/nsp12350E350delGAG---11B.1.177.620.001192
ORF1ab/nsp12350E350EgaGgaA11B.1.177.70.000165
ORF1ab/nsp12350E350EgaGgaA11B.1.177.730.000566
ORF1ab/nsp12350E350delGAG---11B.1.177.760.002494
ORF1ab/nsp12350E350delGAG---11B.1.177.830.001481
ORF1ab/nsp12350E350delGAG---11B.1.1950.005025
ORF1ab/nsp12350E350AgAggCg11B.1.20.000009
ORF1ab/nsp12350E350NGaGAaC11B.1.20.000009
ORF1ab/nsp12350E350XGagTag11B.1.20.000009
ORF1ab/nsp12350E350DgaGgaT11B.1.2210.000071
ORF1ab/nsp12350E350delGAG---11B.1.2210.000071
ORF1ab/nsp12350E350DgaGgaC11B.1.230.006061
ORF1ab/nsp12350E350DgaGgaT11B.1.2320.000537
ORF1ab/nsp12350E350DgaGgaT11B.1.2400.000216
ORF1ab/nsp12350E350delGAG---11B.1.2580.000067
ORF1ab/nsp12350E350XGAGTGA11B.1.2580.000067
ORF1ab/nsp12350E350EgaGgaA11B.1.2800.007143
ORF1ab/nsp12350E350AgAggCg11B.1.3510.00003
ORF1ab/nsp12350E350delGAG---11B.1.351.30.000876
ORF1ab/nsp12350E350delGAG---11B.1.360.000146
ORF1ab/nsp12350E350delGAG---11B.1.36.180.00042
ORF1ab/nsp12350E350delGAG---11B.1.36.310.001751
ORF1ab/nsp12350E350GgAggGg11B.1.3610.001289
ORF1ab/nsp12350E350VgAggTg11B.1.3620.001541
ORF1ab/nsp12350E350GgAggGg11B.1.3620.001541
ORF1ab/nsp12350E350DgaGgaT11B.1.3690.000285
ORF1ab/nsp12350E350DgaGgaT11B.1.3750.00082
ORF1ab/nsp12350E350delGAG---11B.1.3960.000706
ORF1ab/nsp12350E350AgAggCg11B.1.4270.00005
ORF1ab/nsp12350E350delGAG---11B.1.4460.02
ORF1ab/nsp12350E350DgaGgaT11B.1.5150.014493
ORF1ab/nsp12350E350VgAggTg11B.1.5160.001957
ORF1ab/nsp12350E350delGAG---11B.1.5170.000427
ORF1ab/nsp12350E350NGaGAaT11B.1.5250.000113
ORF1ab/nsp12350E350EgaGgaA11B.1.5260.000024
ORF1ab/nsp12350E350DgaGgaT11B.1.5640.000426
ORF1ab/nsp12350E350DgaGgaT11B.1.5680.001111
ORF1ab/nsp12350E350XGagTag11B.1.5740.002151
ORF1ab/nsp12350E350DgaGgaT11B.1.5770.000687
ORF1ab/nsp12350E350delGAG---11B.1.5800.004065
ORF1ab/nsp12350E350VgAGgTA11B.1.617.10.000129
ORF1ab/nsp12350E350DgaGgaT11B.1.617.20.000004
ORF1ab/nsp12350E350NGaGAaT11B.1.617.20.000004
ORF1ab/nsp12350E350EgaGgaA11B.1.6210.000089
ORF1ab/nsp12350E350delGAG---11B.1.6210.000089
ORF1ab/nsp12350E350AgAggCg11B.1.6270.00202
ORF1ab/nsp12350E350delGAG---11B.1.6300.005236
ORF1ab/nsp12350E350delGAG---11B.1.6370.000073
ORF1ab/nsp12350E350DgaGgaT11C.130.025641
ORF1ab/nsp12350E350delGAG---11C.170.055556
ORF1ab/nsp12350E350delGAG---11C.360.000911
ORF1ab/nsp12350E350del1gaGga-11D.20.000075
ORF1ab/nsp12350E350GgAggGg11D.20.000075
ORF1ab/nsp12350E350XGagTag11D.30.005917
ORF1ab/nsp12350E350KGagAag11P.10.000016
ORF1ab/nsp12350E350LGAGCTC11P.10.000016
ORF1ab/nsp12350E350DgaGgaC11P.10.000016
ORF1ab/nsp12350E350delGAG---11P.10.000016
ORF1ab/nsp12350E350delGAG---11P.1.100.000269
ORF1ab/nsp12350E350GgAggGg11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.