CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 300 & Codon = aaT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp12	300	N300N	N4692N	syn	aaC	aaT	12021	12021	1	14338-14340

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp12	300	N300N	aaC	aaT	12021	12021	All	0.002299
ORF1ab/nsp12	300	N300N	aaC	aaT	11075	11075	R.1	0.99685
ORF1ab/nsp12	300	N300N	aaC	aaT	262	262	B.1.1	0.004753
ORF1ab/nsp12	300	N300N	aaC	aaT	100	100	B.1.1.220	0.185874
ORF1ab/nsp12	300	N300N	aaC	aaT	81	81	B.1	0.000742
ORF1ab/nsp12	300	N300N	aaC	aaT	61	61	B.1.1.7	0.000055
ORF1ab/nsp12	300	N300N	aaC	aaT	57	57	B.1.617.2	0.000215
ORF1ab/nsp12	300	N300N	aaC	aaT	55	55	AY.3	0.000547
ORF1ab/nsp12	300	N300N	aaC	aaT	39	39	B.1.2	0.000343
ORF1ab/nsp12	300	N300N	aaC	aaT	34	34	B.1.1.525	0.185792
ORF1ab/nsp12	300	N300N	aaC	aaT	24	24	AY.4	0.000037
ORF1ab/nsp12	300	N300N	aaC	aaT	17	17	B.1.1.317	0.006999
ORF1ab/nsp12	300	N300N	aaC	aaT	16	16	B.1.177	0.000211
ORF1ab/nsp12	300	N300N	aaC	aaT	14	14	AY.103	0.000087
ORF1ab/nsp12	300	N300N	aaC	aaT	14	14	B.1.416	0.017766
ORF1ab/nsp12	300	N300N	aaC	aaT	13	13	AY.35	0.00303
ORF1ab/nsp12	300	N300N	aaC	aaT	12	12	B.1.1.10	0.013378
ORF1ab/nsp12	300	N300N	aaC	aaT	11	11	AY.39	0.000272
ORF1ab/nsp12	300	N300N	aaC	aaT	10	10	AY.25	0.00006
ORF1ab/nsp12	300	N300N	aaC	aaT	8	8	AY.117	0.000676
ORF1ab/nsp12	300	N300N	aaC	aaT	6	6	B.1.1.222	0.001224
ORF1ab/nsp12	300	N300N	aaC	aaT	6	6	D.2	0.00045
ORF1ab/nsp12	300	N300N	aaC	aaT	5	5	AY.16.1	0.00235
ORF1ab/nsp12	300	N300N	aaC	aaT	4	4	AY.43	0.000018
ORF1ab/nsp12	300	N300N	aaC	aaT	4	4	AY.44	0.000024
ORF1ab/nsp12	300	N300N	aaC	aaT	4	4	AY.9.1	0.000335
ORF1ab/nsp12	300	N300N	aaC	aaT	3	3	AY.120	0.000112
ORF1ab/nsp12	300	N300N	aaC	aaT	3	3	B.1.1.39	0.001529
ORF1ab/nsp12	300	N300N	aaC	aaT	3	3	B.1.1.521	0.016043
ORF1ab/nsp12	300	N300N	aaC	aaT	3	3	B.1.108	0.017442
ORF1ab/nsp12	300	N300N	aaC	aaT	3	3	B.1.524	0.004219
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	AY.107	0.000932
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	AY.20	0.000078
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	AY.48	0.00093
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	AY.99.2	0.000184
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.1.25	0.001137
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.1.263	0.003115
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.1.291	0.001485
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.1.51	0.003436
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.1.519	0.000079
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.1.83	0.00542
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.258	0.000133
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.349	0.00143
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	B.1.568	0.002222
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	P.1	0.000032
ORF1ab/nsp12	300	N300N	aaC	aaT	2	2	Q.7	0.002222
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.121	0.000135
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.29	0.000016
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.3.1	0.000085
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.33	0.000067
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.4.2	0.000022
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.4.5	0.000107
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.46	0.000104
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.5	0.000021
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.75	0.000056
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	AY.96	0.002075
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.1	0.000327
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.196	0.005714
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.198	0.001468
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.214	0.000055
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.236	0.006897
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.258	0.003257
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.305	0.003861
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.33	0.000421
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.464	0.001473
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.522	0.017241
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.528	0.004808
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.56	0.017857
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.1.8	0.003584
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.160	0.000031
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.161	0.017241
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.177.23	0.003236
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.177.84	0.006667
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.214.2	0.0006
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.234	0.000132
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.265	0.001271
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.36.19	0.009259
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.375	0.00082
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.427	0.00005
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.429	0.000024
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.436	0.001029
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.468	0.005714
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.517	0.000427
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.533	0.009615
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.564	0.000426
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.596	0.000087
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.604	0.017241
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.1.617.1	0.000129
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	B.23	0.002924
ORF1ab/nsp12	300	N300N	aaC	aaT	1	1	P.1.14	0.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.