CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 269 & Codon = gCt

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12269D269AD4661AnonsyngAtgCt2626114245-14247

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12269D269AgAtgCt2626All0.000005
ORF1ab/nsp12269D269AgAtgCt55A.2.50.002495
ORF1ab/nsp12269D269AgAtgCt44B.1.1.70.000004
ORF1ab/nsp12269D269AgAtgCt33B.1.36.10.003421
ORF1ab/nsp12269D269AgAtgCt22B.1.617.20.000008
ORF1ab/nsp12269D269AgAtgCt11AY.1020.000027
ORF1ab/nsp12269D269AgAtgCt11AY.430.000004
ORF1ab/nsp12269D269AgAtgCt11B0.000128
ORF1ab/nsp12269D269AgAtgCt11B.1.10.000018
ORF1ab/nsp12269D269AgAtgCt11B.1.1.250.000569
ORF1ab/nsp12269D269AgAtgCt11B.1.1770.000013
ORF1ab/nsp12269D269AgAtgCt11B.1.177.450.000381
ORF1ab/nsp12269D269AgAtgCt11B.1.177.600.000218
ORF1ab/nsp12269D269AgAtgCt11B.1.5260.000024
ORF1ab/nsp12269D269AgAtgCt11B.1.617.10.000129
ORF1ab/nsp12269D269AgAtgCt11P.10.000016
ORF1ab/nsp12269D269AgAtgCt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.