CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 228

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12228G228SG4620SnonsynGgtAgt8538500.99648314122-14124
ORF1ab/nsp12228G228SG4620SnonsynGgTAgC85330.00351714122-14124
ORF1ab/nsp12228G228CG4620CnonsynGgtTgt574574114122-14124
ORF1ab/nsp12228G228DG4620DnonsyngGtgAt329329114122-14124
ORF1ab/nsp12228G228GG4620GsynggTggC72700.97222214122-14124
ORF1ab/nsp12228G228GG4620GsynggTggG7220.027777814122-14124
ORF1ab/nsp12228G228VG4620VnonsyngGtgTt50470.9414122-14124
ORF1ab/nsp12228G228VG4620VnonsyngGTgTC5020.0414122-14124
ORF1ab/nsp12228G228VG4620VnonsyngGTgTG5010.0214122-14124
ORF1ab/nsp12228G228AG4620AnonsyngGtgCt44430.97727314122-14124
ORF1ab/nsp12228G228AG4620AnonsyngGTgCC4410.022727314122-14124
ORF1ab/nsp12228G228delG4620deldelGGT---1414114122-14124
ORF1ab/nsp12228G228RG4620RnonsynGgtCgt1090.914122-14124
ORF1ab/nsp12228G228RG4620RnonsynGgTAgG1010.114122-14124
ORF1ab/nsp12228G228IG4620InonsynGGtATt420.514122-14124
ORF1ab/nsp12228G228IG4620InonsynGGTATC420.514122-14124
ORF1ab/nsp12228G228WG4620WnonsynGgTTgG11114122-14124
ORF1ab/nsp12228G228MG4620MnonsynGGTATG11114122-14124

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12228G228SGgtAgt850853All0.000163
ORF1ab/nsp12228G228SGgTAgC3853All0.000001
ORF1ab/nsp12228G228SGgtAgt590590B.1.617.20.002222
ORF1ab/nsp12228G228CGgtTgt574574All0.00011
ORF1ab/nsp12228G228DgGtgAt329329All0.000063
ORF1ab/nsp12228G228CGgtTgt135135AY.1030.000838
ORF1ab/nsp12228G228CGgtTgt7777AY.40.00012
ORF1ab/nsp12228G228GggTggC7072All0.000013
ORF1ab/nsp12228G228GggTggG272All0
ORF1ab/nsp12228G228DgGtgAt6363AY.250.000379
ORF1ab/nsp12228G228CGgtTgt6161B.1.36.231
ORF1ab/nsp12228G228DgGtgAt5353AY.40.000082
ORF1ab/nsp12228G228VgGtgTt4750All0.000009
ORF1ab/nsp12228G228VgGTgTC250All0
ORF1ab/nsp12228G228VgGTgTG150All0
ORF1ab/nsp12228G228SGgtAgt4646B.1.1.70.000041
ORF1ab/nsp12228G228AgGtgCt4344All0.000008
ORF1ab/nsp12228G228AgGTgCC144All0
ORF1ab/nsp12228G228AgGtgCt4040B.1.1.70.000036
ORF1ab/nsp12228G228DgGtgAt3333B.1.1.70.00003
ORF1ab/nsp12228G228CGgtTgt3232AY.430.000142
ORF1ab/nsp12228G228CGgtTgt3131B.1.1.70.000028
ORF1ab/nsp12228G228CGgtTgt2929AY.260.000821
ORF1ab/nsp12228G228SGgtAgt2828AY.560.044944
ORF1ab/nsp12228G228DgGtgAt2727B.1.6210.00239
ORF1ab/nsp12228G228CGgtTgt2424B.1.1.1440.685714
ORF1ab/nsp12228G228CGgtTgt2424B.1.617.20.00009
ORF1ab/nsp12228G228DgGtgAt2323AY.30.000229
ORF1ab/nsp12228G228GggTggC2323B.1.1.70.000021
ORF1ab/nsp12228G228SGgtAgt2020AY.40.000031
ORF1ab/nsp12228G228DgGtgAt2020B.1.5700.058824
ORF1ab/nsp12228G228SGgtAgt1919B.1.5260.000447
ORF1ab/nsp12228G228CGgtTgt1818B.10.000165
ORF1ab/nsp12228G228DgGtgAt1616AY.430.000071
ORF1ab/nsp12228G228CGgtTgt1515B.1.5260.000353
ORF1ab/nsp12228G228delGGT---1414All0.000003
ORF1ab/nsp12228G228GggTggC1313B.1.5260.000306
ORF1ab/nsp12228G228CGgtTgt1212B.1.214.20.007194
ORF1ab/nsp12228G228RGgtCgt910All0.000002
ORF1ab/nsp12228G228RGgTAgG110All0
ORF1ab/nsp12228G228DgGtgAt99AY.440.000055
ORF1ab/nsp12228G228SGgtAgt99B.10.000082
ORF1ab/nsp12228G228CGgtTgt88A0.003096
ORF1ab/nsp12228G228SGgtAgt88AY.400.007715
ORF1ab/nsp12228G228DgGtgAt88AY.470.000249
ORF1ab/nsp12228G228VgGtgTt88B.1.1.70.000007
ORF1ab/nsp12228G228CGgtTgt77AY.1070.003262
ORF1ab/nsp12228G228SGgtAgt77AY.16.10.003289
ORF1ab/nsp12228G228CGgtTgt77P.1.70.002235
ORF1ab/nsp12228G228DgGtgAt66B.10.000055
ORF1ab/nsp12228G228CGgtTgt66P.10.000095
ORF1ab/nsp12228G228VgGTgTC250.111111
ORF1ab/nsp12228G228VgGtgTt250.111111
ORF1ab/nsp12228G228VgGTgTG150.055556
ORF1ab/nsp12228G228DgGtgAt55AY.1210.000677
ORF1ab/nsp12228G228SGgtAgt55AY.200.000194
ORF1ab/nsp12228G228CGgtTgt55AY.250.00003
ORF1ab/nsp12228G228GggTggC55AY.40.000008
ORF1ab/nsp12228G228CGgtTgt55AY.4.30.004209
ORF1ab/nsp12228G228SGgtAgt55AY.420.000201
ORF1ab/nsp12228G228GggTggC55AY.46.60.000361
ORF1ab/nsp12228G228GggTggC55B.1.1.4340.001743
ORF1ab/nsp12228G228delGGT---55B.1.1.70.000004
ORF1ab/nsp12228G228CGgtTgt55B.1.1770.000066
ORF1ab/nsp12228G228VgGtgTt55B.1.617.20.000019
ORF1ab/nsp12228G228VgGtgTt55D.20.000375
ORF1ab/nsp12228G228SGgtAgt240.111111
ORF1ab/nsp12228G228SGgTAgC240.111111
ORF1ab/nsp12228G228IGGTATC240.111111
ORF1ab/nsp12228G228IGGtATt240.111111
ORF1ab/nsp12228G228IGGtATt24All0
ORF1ab/nsp12228G228IGGTATC24All0
ORF1ab/nsp12228G228CGgtTgt44AY.1020.000106
ORF1ab/nsp12228G228SGgtAgt44AY.1030.000025
ORF1ab/nsp12228G228CGgtTgt44AY.30.00004
ORF1ab/nsp12228G228CGgtTgt44AY.440.000024
ORF1ab/nsp12228G228SGgtAgt44AY.480.00186
ORF1ab/nsp12228G228CGgtTgt44AY.750.000224
ORF1ab/nsp12228G228CGgtTgt44B0.000511
ORF1ab/nsp12228G228SGgtAgt44B.1.2340.000528
ORF1ab/nsp12228G228SGgtAgt44B.1.3510.000119
ORF1ab/nsp12228G228VgGtgTt44B.1.5960.000349
ORF1ab/nsp12228G228DgGtgAt44D.20.0003
ORF1ab/nsp12228G228DgGtgAt44P.10.000063
ORF1ab/nsp12228G228SGgtAgt44P.1.140.000191
ORF1ab/nsp12228G228SGgtAgt44Q.30.00058
ORF1ab/nsp12228G228GggTggC230.111111
ORF1ab/nsp12228G228GggTggG130.055556
ORF1ab/nsp12228G228DgGtgAt33AY.1020.00008
ORF1ab/nsp12228G228SGgtAgt33AY.1200.000112
ORF1ab/nsp12228G228SGgtAgt33AY.390.000074
ORF1ab/nsp12228G228CGgtTgt33AY.390.000074
ORF1ab/nsp12228G228CGgtTgt33AY.420.000121
ORF1ab/nsp12228G228SGgtAgt33AY.430.000013
ORF1ab/nsp12228G228CGgtTgt33AY.470.000093
ORF1ab/nsp12228G228SGgtAgt33AY.520.002443
ORF1ab/nsp12228G228SGgtAgt33AY.680.000821
ORF1ab/nsp12228G228DgGtgAt33B.1.10.000054
ORF1ab/nsp12228G228SGgtAgt33B.1.1.3060.001315
ORF1ab/nsp12228G228SGgtAgt33B.1.1.5190.000119
ORF1ab/nsp12228G228RGgtCgt33B.1.20.000026
ORF1ab/nsp12228G228DgGtgAt33B.1.20.000026
ORF1ab/nsp12228G228SGgtAgt33B.1.20.000026
ORF1ab/nsp12228G228DgGtgAt33B.1.2580.0002
ORF1ab/nsp12228G228SGgtAgt33B.1.258.170.000312
ORF1ab/nsp12228G228SGgtAgt33B.1.3460.003932
ORF1ab/nsp12228G228DgGtgAt33B.1.3610.003866
ORF1ab/nsp12228G228DgGtgAt33B.1.4040.003906
ORF1ab/nsp12228G228DgGtgAt33B.1.617.20.000011
ORF1ab/nsp12228G228SGgtAgt22AY.1020.000053
ORF1ab/nsp12228G228GggTggC22AY.1020.000053
ORF1ab/nsp12228G228VgGtgTt22AY.1030.000012
ORF1ab/nsp12228G228CGgtTgt22AY.120.10.000642
ORF1ab/nsp12228G228CGgtTgt22AY.140.000176
ORF1ab/nsp12228G228SGgtAgt22AY.250.000012
ORF1ab/nsp12228G228GggTggC22AY.30.00002
ORF1ab/nsp12228G228CGgtTgt22AY.360.000296
ORF1ab/nsp12228G228SGgtAgt22AY.470.000062
ORF1ab/nsp12228G228SGgtAgt22AY.550.001835
ORF1ab/nsp12228G228SGgtAgt22AY.640.00119
ORF1ab/nsp12228G228SGgtAgt22AY.75.10.000361
ORF1ab/nsp12228G228SGgtAgt22AY.9.20.000073
ORF1ab/nsp12228G228SGgtAgt22AY.98.10.000097
ORF1ab/nsp12228G228DgGtgAt22AY.99.20.000184
ORF1ab/nsp12228G228VgGtgTt22B.10.000018
ORF1ab/nsp12228G228GggTggC12B.10.000009
ORF1ab/nsp12228G228GggTggG12B.10.000009
ORF1ab/nsp12228G228CGgtTgt22B.1.10.000036
ORF1ab/nsp12228G228DgGtgAt22B.1.1.4130.013793
ORF1ab/nsp12228G228DgGtgAt22B.1.1.5190.000079
ORF1ab/nsp12228G228RGgtCgt22B.1.1770.000026
ORF1ab/nsp12228G228VgGtgTt22B.1.20.000018
ORF1ab/nsp12228G228CGgtTgt22B.1.2400.000431
ORF1ab/nsp12228G228DgGtgAt22B.1.2430.000139
ORF1ab/nsp12228G228SGgtAgt22B.1.2890.005319
ORF1ab/nsp12228G228CGgtTgt22B.1.3110.000549
ORF1ab/nsp12228G228CGgtTgt22B.1.4270.000101
ORF1ab/nsp12228G228DgGtgAt22B.1.4270.000101
ORF1ab/nsp12228G228CGgtTgt22B.1.4290.000047
ORF1ab/nsp12228G228GggTggC22B.1.4290.000047
ORF1ab/nsp12228G228GggTggC22B.1.4370.041667
ORF1ab/nsp12228G228delGGT---22B.1.5250.000226
ORF1ab/nsp12228G228DgGtgAt22B.1.5260.000047
ORF1ab/nsp12228G228DgGtgAt22B.1.6280.000705
ORF1ab/nsp12228G228VgGtgTt22B.1.6370.000146
ORF1ab/nsp12228G228SGgtAgt22P.10.000032
ORF1ab/nsp12228G228SGgtAgt22Q.80.00033
ORF1ab/nsp12228G228MGGTATG110.055556
ORF1ab/nsp12228G228RGgTAgG110.055556
ORF1ab/nsp12228G228VgGtgTt11A.2.50.000499
ORF1ab/nsp12228G228WGgTTgG11All0
ORF1ab/nsp12228G228MGGTATG11All0
ORF1ab/nsp12228G228CGgtTgt11AY.1110.000183
ORF1ab/nsp12228G228CGgtTgt11AY.1130.000142
ORF1ab/nsp12228G228DgGtgAt11AY.1170.000085
ORF1ab/nsp12228G228SGgtAgt11AY.1180.000063
ORF1ab/nsp12228G228SGgtAgt11AY.1190.000035
ORF1ab/nsp12228G228delGGT---11AY.1200.000037
ORF1ab/nsp12228G228SGgtAgt11AY.130.000161
ORF1ab/nsp12228G228SGgtAgt11AY.140.000088
ORF1ab/nsp12228G228GggTggC11AY.160.00038
ORF1ab/nsp12228G228SGgtAgt11AY.190.00114
ORF1ab/nsp12228G228GggTggC11AY.230.00007
ORF1ab/nsp12228G228VgGtgTt11AY.240.000431
ORF1ab/nsp12228G228VgGtgTt11AY.250.000006
ORF1ab/nsp12228G228RGgtCgt11AY.250.000006
ORF1ab/nsp12228G228SGgtAgt11AY.260.000028
ORF1ab/nsp12228G228SGgtAgt11AY.270.000065
ORF1ab/nsp12228G228DgGtgAt11AY.280.00189
ORF1ab/nsp12228G228SGgtAgt11AY.280.00189
ORF1ab/nsp12228G228CGgtTgt11AY.280.00189
ORF1ab/nsp12228G228SGgtAgt11AY.290.000016
ORF1ab/nsp12228G228CGgtTgt11AY.290.000016
ORF1ab/nsp12228G228SGgtAgt11AY.30.00001
ORF1ab/nsp12228G228SGgtAgt11AY.3.10.000085
ORF1ab/nsp12228G228SGgtAgt11AY.310.018519
ORF1ab/nsp12228G228SGgtAgt11AY.320.000532
ORF1ab/nsp12228G228DgGtgAt11AY.360.000148
ORF1ab/nsp12228G228CGgtTgt11AY.380.000499
ORF1ab/nsp12228G228DgGtgAt11AY.390.000025
ORF1ab/nsp12228G228CGgtTgt11AY.39.10.00004
ORF1ab/nsp12228G228VgGtgTt11AY.4.20.000022
ORF1ab/nsp12228G228CGgtTgt11AY.4.50.000107
ORF1ab/nsp12228G228VgGtgTt11AY.430.000004
ORF1ab/nsp12228G228SGgtAgt11AY.440.000006
ORF1ab/nsp12228G228GggTggC11AY.440.000006
ORF1ab/nsp12228G228SGgtAgt11AY.460.000104
ORF1ab/nsp12228G228CGgtTgt11AY.5.30.000337
ORF1ab/nsp12228G228delGGT---11AY.5.30.000337
ORF1ab/nsp12228G228CGgtTgt11AY.590.00053
ORF1ab/nsp12228G228SGgtAgt11AY.610.000105
ORF1ab/nsp12228G228delGGT---11AY.650.000533
ORF1ab/nsp12228G228VgGtgTt11AY.720.001361
ORF1ab/nsp12228G228delGGT---11AY.80.000606
ORF1ab/nsp12228G228VgGtgTt11AY.850.000427
ORF1ab/nsp12228G228SGgtAgt11AY.880.000884
ORF1ab/nsp12228G228DgGtgAt11AY.9.10.000084
ORF1ab/nsp12228G228CGgtTgt11AY.9.20.000037
ORF1ab/nsp12228G228CGgtTgt11AY.940.000443
ORF1ab/nsp12228G228SGgtAgt11AY.99.20.000092
ORF1ab/nsp12228G228AgGTgCC11B.10.000009
ORF1ab/nsp12228G228delGGT---11B.1.10.000018
ORF1ab/nsp12228G228delGGT---11B.1.1.10.000327
ORF1ab/nsp12228G228DgGtgAt11B.1.1.10.000327
ORF1ab/nsp12228G228GggTggC11B.1.1.2070.001182
ORF1ab/nsp12228G228CGgtTgt11B.1.1.2140.000055
ORF1ab/nsp12228G228CGgtTgt11B.1.1.2770.000759
ORF1ab/nsp12228G228DgGtgAt11B.1.1.2840.000107
ORF1ab/nsp12228G228SGgtAgt11B.1.1.2940.001266
ORF1ab/nsp12228G228DgGtgAt11B.1.1.2940.001266
ORF1ab/nsp12228G228SGgtAgt11B.1.1.3050.003861
ORF1ab/nsp12228G228SGgtAgt11B.1.1.3150.008475
ORF1ab/nsp12228G228SGgTAgC11B.1.1.4090.002833
ORF1ab/nsp12228G228CGgtTgt11B.1.1.440.00241
ORF1ab/nsp12228G228CGgtTgt11B.1.1.5190.00004
ORF1ab/nsp12228G228RGgtCgt11B.1.1.5190.00004
ORF1ab/nsp12228G228SGgtAgt11B.1.1.5210.005348
ORF1ab/nsp12228G228SGgtAgt11B.1.1460.004237
ORF1ab/nsp12228G228SGgtAgt11B.1.1590.012195
ORF1ab/nsp12228G228VgGtgTt11B.1.1770.000013
ORF1ab/nsp12228G228SGgtAgt11B.1.177.110.001698
ORF1ab/nsp12228G228DgGtgAt11B.1.177.730.000566
ORF1ab/nsp12228G228SGgtAgt11B.1.177.810.000189
ORF1ab/nsp12228G228delGGT---11B.1.20.000009
ORF1ab/nsp12228G228CGgtTgt11B.1.20.000009
ORF1ab/nsp12228G228WGgTTgG11B.1.20.000009
ORF1ab/nsp12228G228SGgtAgt11B.1.2140.003663
ORF1ab/nsp12228G228SGgtAgt11B.1.2210.000071
ORF1ab/nsp12228G228CGgtTgt11B.1.2340.000132
ORF1ab/nsp12228G228DgGtgAt11B.1.2400.000216
ORF1ab/nsp12228G228VgGtgTt11B.1.2400.000216
ORF1ab/nsp12228G228RGgtCgt11B.1.2580.000067
ORF1ab/nsp12228G228VgGtgTt11B.1.2580.000067
ORF1ab/nsp12228G228SGgtAgt11B.1.2580.000067
ORF1ab/nsp12228G228SGgtAgt11B.1.258.140.00098
ORF1ab/nsp12228G228DgGtgAt11B.1.2980.002114
ORF1ab/nsp12228G228CGgtTgt11B.1.3190.003049
ORF1ab/nsp12228G228DgGtgAt11B.1.3510.00003
ORF1ab/nsp12228G228VgGtgTt11B.1.351.30.000876
ORF1ab/nsp12228G228SGgtAgt11B.1.360.000146
ORF1ab/nsp12228G228CGgtTgt11B.1.360.000146
ORF1ab/nsp12228G228SGgtAgt11B.1.36.360.000602
ORF1ab/nsp12228G228DgGtgAt11B.1.36.80.001
ORF1ab/nsp12228G228CGgtTgt11B.1.3960.000706
ORF1ab/nsp12228G228DgGtgAt11B.1.3990.001934
ORF1ab/nsp12228G228DgGtgAt11B.1.4290.000024
ORF1ab/nsp12228G228AgGtgCt11B.1.4290.000024
ORF1ab/nsp12228G228CGgtTgt11B.1.438.10.000107
ORF1ab/nsp12228G228DgGtgAt11B.1.4500.011364
ORF1ab/nsp12228G228DgGtgAt11B.1.4510.008197
ORF1ab/nsp12228G228GggTggC11B.1.466.20.000391
ORF1ab/nsp12228G228VgGtgTt11B.1.4710.002732
ORF1ab/nsp12228G228DgGtgAt11B.1.5170.000427
ORF1ab/nsp12228G228CGgtTgt11B.1.5170.000427
ORF1ab/nsp12228G228CGgtTgt11B.1.5250.000113
ORF1ab/nsp12228G228DgGtgAt11B.1.5250.000113
ORF1ab/nsp12228G228VgGtgTt11B.1.5260.000024
ORF1ab/nsp12228G228AgGtgCt11B.1.5510.00129
ORF1ab/nsp12228G228DgGtgAt11B.1.5820.000491
ORF1ab/nsp12228G228CGgtTgt11B.1.5960.000087
ORF1ab/nsp12228G228RGgtCgt11B.1.617.20.000004
ORF1ab/nsp12228G228GggTggC11B.1.617.20.000004
ORF1ab/nsp12228G228AgGtgCt11B.1.617.20.000004
ORF1ab/nsp12228G228GggTggC11B.1.6210.000089
ORF1ab/nsp12228G228CGgtTgt11B.1.621.10.000506
ORF1ab/nsp12228G228DgGtgAt11B.1.6230.000536
ORF1ab/nsp12228G228VgGtgTt11B.30.000831
ORF1ab/nsp12228G228CGgtTgt11B.4.60.016667
ORF1ab/nsp12228G228SGgtAgt11C.10.002392
ORF1ab/nsp12228G228GggTggC11D.20.000075
ORF1ab/nsp12228G228CGgtTgt11D.20.000075
ORF1ab/nsp12228G228SGgtAgt11D.20.000075
ORF1ab/nsp12228G228VgGtgTt11P.10.000016
ORF1ab/nsp12228G228CGgtTgt11P.1.100.000269
ORF1ab/nsp12228G228DgGtgAt11P.1.140.000048
ORF1ab/nsp12228G228SGgtAgt11P.20.000187
ORF1ab/nsp12228G228DgGtgAt11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.