CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 225

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp12	225	T225T	T4617T	syn	acC	acT	850	741	0.871765	14113-14115
ORF1ab/nsp12	225	T225T	T4617T	syn	acC	acA	850	106	0.124706	14113-14115
ORF1ab/nsp12	225	T225T	T4617T	syn	acC	acG	850	3	0.00352941	14113-14115
ORF1ab/nsp12	225	T225A	T4617A	nonsyn	Acc	Gcc	551	548	0.994555	14113-14115
ORF1ab/nsp12	225	T225A	T4617A	nonsyn	AcC	GcT	551	2	0.00362976	14113-14115
ORF1ab/nsp12	225	T225A	T4617A	nonsyn	AcC	GcA	551	1	0.00181488	14113-14115
ORF1ab/nsp12	225	T225I	T4617I	nonsyn	aCc	aTc	394	393	0.997462	14113-14115
ORF1ab/nsp12	225	T225I	T4617I	nonsyn	aCC	aTT	394	1	0.00253807	14113-14115
ORF1ab/nsp12	225	T225N	T4617N	nonsyn	aCc	aAc	42	41	0.97619	14113-14115
ORF1ab/nsp12	225	T225N	T4617N	nonsyn	aCC	aAT	42	1	0.0238095	14113-14115
ORF1ab/nsp12	225	T225P	T4617P	nonsyn	Acc	Ccc	39	39	1	14113-14115
ORF1ab/nsp12	225	T225del	T4617del	del	ACC	---	13	13	1	14113-14115
ORF1ab/nsp12	225	T225S	T4617S	nonsyn	Acc	Tcc	3	3	1	14113-14115
ORF1ab/nsp12	225	T225D	T4617D	nonsyn	ACc	GAc	3	2	0.666667	14113-14115
ORF1ab/nsp12	225	T225D	T4617D	nonsyn	ACC	GAT	3	1	0.333333	14113-14115
ORF1ab/nsp12	225	T225del1	T4617del1	del	acC	ac-	1	1	1	14113-14115
ORF1ab/nsp12	225	T225K	T4617K	nonsyn	aCC	aAA	1	1	1	14113-14115
ORF1ab/nsp12	225	T225V	T4617V	nonsyn	ACc	GTc	1	1	1	14113-14115
ORF1ab/nsp12	225	T225E	T4617E	nonsyn	ACC	GAA	1	1	1	14113-14115

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp12	225	T225T	acC	acT	741	850	All	0.000142
ORF1ab/nsp12	225	T225T	acC	acA	106	850	All	0.00002
ORF1ab/nsp12	225	T225T	acC	acG	3	850	All	0.000001
ORF1ab/nsp12	225	T225A	Acc	Gcc	548	551	All	0.000105
ORF1ab/nsp12	225	T225A	AcC	GcT	2	551	All	0
ORF1ab/nsp12	225	T225A	AcC	GcA	1	551	All	0
ORF1ab/nsp12	225	T225I	aCc	aTc	393	394	All	0.000075
ORF1ab/nsp12	225	T225I	aCC	aTT	1	394	All	0
ORF1ab/nsp12	225	T225A	Acc	Gcc	306	306	P.6	0.962264
ORF1ab/nsp12	225	T225T	acC	acT	137	142	B.1.1.7	0.000123
ORF1ab/nsp12	225	T225T	acC	acG	3	142	B.1.1.7	0.000003
ORF1ab/nsp12	225	T225T	acC	acA	2	142	B.1.1.7	0.000002
ORF1ab/nsp12	225	T225T	acC	acT	95	106	B.1.617.2	0.000358
ORF1ab/nsp12	225	T225T	acC	acA	11	106	B.1.617.2	0.000041
ORF1ab/nsp12	225	T225T	acC	acT	101	103	AY.26	0.002859
ORF1ab/nsp12	225	T225T	acC	acA	2	103	AY.26	0.000057
ORF1ab/nsp12	225	T225I	aCc	aTc	75	75	B.1.1.7	0.000067
ORF1ab/nsp12	225	T225A	Acc	Gcc	75	75	B.1.1.7	0.000067
ORF1ab/nsp12	225	T225T	acC	acT	42	64	AY.4	0.000065
ORF1ab/nsp12	225	T225T	acC	acA	22	64	AY.4	0.000034
ORF1ab/nsp12	225	T225A	Acc	Gcc	63	63	AY.42	0.002534
ORF1ab/nsp12	225	T225T	acC	acT	47	47	B.1.2	0.000414
ORF1ab/nsp12	225	T225T	acC	acT	46	46	AY.43	0.000204
ORF1ab/nsp12	225	T225I	aCc	aTc	46	46	AY.43	0.000204
ORF1ab/nsp12	225	T225T	acC	acT	46	46	AY.59	0.024364
ORF1ab/nsp12	225	T225N	aCc	aAc	41	42	All	0.000008
ORF1ab/nsp12	225	T225N	aCC	aAT	1	42	All	0
ORF1ab/nsp12	225	T225P	Acc	Ccc	39	39	All	0.000007
ORF1ab/nsp12	225	T225I	aCc	aTc	30	30	AY.103	0.000186
ORF1ab/nsp12	225	T225P	Acc	Ccc	28	28	B.1.1.7	0.000025
ORF1ab/nsp12	225	T225I	aCc	aTc	26	27	B.1.617.2	0.000098
ORF1ab/nsp12	225	T225I	aCC	aTT	1	27	B.1.617.2	0.000004
ORF1ab/nsp12	225	T225I	aCc	aTc	21	21	B.1.429	0.000494
ORF1ab/nsp12	225	T225I	aCc	aTc	20	20	AY.4	0.000031
ORF1ab/nsp12	225	T225I	aCc	aTc	19	19	B.1.427	0.000959
ORF1ab/nsp12	225	T225I	aCc	aTc	17	17	AY.44	0.000103
ORF1ab/nsp12	225	T225T	acC	acT	14	17	AY.44	0.000085
ORF1ab/nsp12	225	T225T	acC	acA	3	17	AY.44	0.000018
ORF1ab/nsp12	225	T225T	acC	acT	17	17	B.1.1.284	0.001826
ORF1ab/nsp12	225	T225T	acC	acT	17	17	B.1.1.337	0.061151
ORF1ab/nsp12	225	T225I	aCc	aTc	17	17	B.1.177	0.000224
ORF1ab/nsp12	225	T225T	acC	acA	15	17	B.1.177	0.000198
ORF1ab/nsp12	225	T225T	acC	acT	2	17	B.1.177	0.000026
ORF1ab/nsp12	225	T225I	aCc	aTc	16	16	B.1	0.000147
ORF1ab/nsp12	225	T225del	ACC	---	13	13	All	0.000002
ORF1ab/nsp12	225	T225T	acC	acT	12	13	AY.103	0.000075
ORF1ab/nsp12	225	T225T	acC	acA	1	13	AY.103	0.000006
ORF1ab/nsp12	225	T225I	aCc	aTc	12	12	AY.47	0.000373
ORF1ab/nsp12	225	T225T	acC	acT	11	11	P.1	0.000173
ORF1ab/nsp12	225	T225T	acC	acA	5	10	AY.25	0.00003
ORF1ab/nsp12	225	T225T	acC	acT	5	10	AY.25	0.00003
ORF1ab/nsp12	225	T225T	acC	acT	9	10	AY.3	0.00009
ORF1ab/nsp12	225	T225T	acC	acA	1	10	AY.3	0.00001
ORF1ab/nsp12	225	T225T	acC	acA	10	10	B.1.1.189	0.015129
ORF1ab/nsp12	225	T225T	acC	acT	9	10	B.1.160	0.000281
ORF1ab/nsp12	225	T225T	acC	acA	1	10	B.1.160	0.000031
ORF1ab/nsp12	225	T225N	aCc	aAc	9	9	AY.117	0.000761
ORF1ab/nsp12	225	T225T	acC	acT	9	9	AY.5	0.000186
ORF1ab/nsp12	225	T225T	acC	acT	9	9	B.1.177.4	0.0019
ORF1ab/nsp12	225	T225T	acC	acT	6	8	B.1	0.000055
ORF1ab/nsp12	225	T225T	acC	acA	2	8	B.1	0.000018
ORF1ab/nsp12	225	T225A	Acc	Gcc	8	8	B.1.160	0.00025
ORF1ab/nsp12	225	T225A	Acc	Gcc	8	8	B.1.177	0.000105
ORF1ab/nsp12	225	T225I	aCc	aTc	8	8	B.1.351	0.000238
ORF1ab/nsp12	225	T225T	acC	acA	4	7	AY.20	0.000155
ORF1ab/nsp12	225	T225T	acC	acT	3	7	AY.20	0.000117
ORF1ab/nsp12	225	T225A	Acc	Gcc	7	7	AY.35	0.001631
ORF1ab/nsp12	225	T225T	acC	acT	5	7	AY.39	0.000124
ORF1ab/nsp12	225	T225T	acC	acA	2	7	AY.39	0.000049
ORF1ab/nsp12	225	T225A	Acc	Gcc	7	7	B.1	0.000064
ORF1ab/nsp12	225	T225T	acC	acT	7	7	B.1.1	0.000127
ORF1ab/nsp12	225	T225I	aCc	aTc	7	7	B.1.2	0.000062
ORF1ab/nsp12	225	T225I	aCc	aTc	7	7	B.1.637	0.000512
ORF1ab/nsp12	225	T225T	acC	acT	6	6	AY.119	0.000212
ORF1ab/nsp12	225	T225A	Acc	Gcc	6	6	B.1.617.2	0.000023
ORF1ab/nsp12	225	T225T	acC	acT	4	5	AY.100	0.000184
ORF1ab/nsp12	225	T225T	acC	acA	1	5	AY.100	0.000046
ORF1ab/nsp12	225	T225I	aCc	aTc	5	5	AY.121	0.000677
ORF1ab/nsp12	225	T225T	acC	acT	5	5	AY.75.1	0.000902
ORF1ab/nsp12	225	T225N	aCc	aAc	5	5	B.1.1.7	0.000004
ORF1ab/nsp12	225	T225N	aCc	aAc	5	5	B.1.637	0.000365
ORF1ab/nsp12	225	T225A	Acc	Gcc	2	4		0.111111
ORF1ab/nsp12	225	T225A	AcC	GcT	1	4		0.055556
ORF1ab/nsp12	225	T225A	AcC	GcA	1	4		0.055556
ORF1ab/nsp12	225	T225T	acC	acT	3	4	AY.102	0.00008
ORF1ab/nsp12	225	T225T	acC	acA	1	4	AY.102	0.000027
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	AY.103	0.000025
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	AY.25	0.000024
ORF1ab/nsp12	225	T225N	aCc	aAc	4	4	AY.3	0.00004
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	AY.34	0.000388
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	AY.43	0.000018
ORF1ab/nsp12	225	T225T	acC	acT	4	4	AY.6	0.000165
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	AY.68	0.001095
ORF1ab/nsp12	225	T225del	ACC	---	4	4	B.1.1.7	0.000004
ORF1ab/nsp12	225	T225T	acC	acT	4	4	B.1.427	0.000202
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	B.1.429	0.000094
ORF1ab/nsp12	225	T225T	acC	acT	3	4	B.1.429	0.000071
ORF1ab/nsp12	225	T225T	acC	acA	1	4	B.1.429	0.000024
ORF1ab/nsp12	225	T225I	aCc	aTc	4	4	B.1.526	0.000094
ORF1ab/nsp12	225	T225T	acC	acA	4	4	C.36.3	0.002269
ORF1ab/nsp12	225	T225A	Acc	Gcc	4	4	P.1	0.000063
ORF1ab/nsp12	225	T225N	aCc	aAc	2	3		0.111111
ORF1ab/nsp12	225	T225D	ACc	GAc	2	3		0.111111
ORF1ab/nsp12	225	T225D	ACC	GAT	1	3		0.055556
ORF1ab/nsp12	225	T225N	aCC	aAT	1	3		0.055556
ORF1ab/nsp12	225	T225S	Acc	Tcc	3	3	All	0.000001
ORF1ab/nsp12	225	T225D	ACc	GAc	2	3	All	0
ORF1ab/nsp12	225	T225D	ACC	GAT	1	3	All	0
ORF1ab/nsp12	225	T225T	acC	acT	3	3	AY.117	0.000254
ORF1ab/nsp12	225	T225T	acC	acT	3	3	AY.4.2	0.000065
ORF1ab/nsp12	225	T225I	aCc	aTc	3	3	AY.6	0.000123
ORF1ab/nsp12	225	T225P	Acc	Ccc	3	3	B.1.1	0.000054
ORF1ab/nsp12	225	T225A	Acc	Gcc	2	3	B.1.1.28	0.000622
ORF1ab/nsp12	225	T225A	AcC	GcT	1	3	B.1.1.28	0.000311
ORF1ab/nsp12	225	T225T	acC	acT	3	3	B.1.1.336	0.05
ORF1ab/nsp12	225	T225A	Acc	Gcc	3	3	B.1.177.48	0.009375
ORF1ab/nsp12	225	T225A	Acc	Gcc	3	3	C.37	0.000348
ORF1ab/nsp12	225	T225T	acC	acT	3	3	R.1	0.00027
ORF1ab/nsp12	225	T225T	acC	acT	1	2		0.055556
ORF1ab/nsp12	225	T225T	acC	acA	1	2		0.055556
ORF1ab/nsp12	225	T225N	aCc	aAc	2	2	AY.102	0.000053
ORF1ab/nsp12	225	T225T	acC	acA	1	2	AY.113	0.000142
ORF1ab/nsp12	225	T225T	acC	acT	1	2	AY.113	0.000142
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.117	0.000169
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.120	0.000074
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.14	0.000176
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.16	0.000759
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.25	0.000012
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.26	0.000057
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.29	0.000032
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.3	0.00002
ORF1ab/nsp12	225	T225A	Acc	Gcc	2	2	AY.3	0.00002
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.32	0.001065
ORF1ab/nsp12	225	T225T	acC	acT	1	2	AY.33	0.000067
ORF1ab/nsp12	225	T225T	acC	acA	1	2	AY.33	0.000067
ORF1ab/nsp12	225	T225T	acC	acT	2	2	AY.34	0.000194
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.39	0.000049
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.39.1	0.000079
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.39.2	0.003082
ORF1ab/nsp12	225	T225A	Acc	Gcc	2	2	AY.4	0.000003
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.42	0.00008
ORF1ab/nsp12	225	T225T	acC	acT	2	2	AY.46.3	0.001867
ORF1ab/nsp12	225	T225N	aCc	aAc	2	2	AY.46.6	0.000144
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.5	0.000041
ORF1ab/nsp12	225	T225N	aCc	aAc	2	2	AY.67	0.000929
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	AY.75	0.000112
ORF1ab/nsp12	225	T225T	acC	acT	2	2	AY.75	0.000112
ORF1ab/nsp12	225	T225T	acC	acT	2	2	AY.85	0.000854
ORF1ab/nsp12	225	T225T	acC	acT	2	2	AY.98	0.000158
ORF1ab/nsp12	225	T225T	acC	acA	2	2	AY.98.1	0.000097
ORF1ab/nsp12	225	T225A	Acc	Gcc	2	2	B.1.1	0.000036
ORF1ab/nsp12	225	T225T	acC	acT	2	2	B.1.1.306	0.000877
ORF1ab/nsp12	225	T225T	acC	acT	2	2	B.1.1.519	0.000079
ORF1ab/nsp12	225	T225A	Acc	Gcc	2	2	B.1.160.25	0.022222
ORF1ab/nsp12	225	T225T	acC	acT	2	2	B.1.258	0.000133
ORF1ab/nsp12	225	T225P	Acc	Ccc	2	2	B.1.258	0.000133
ORF1ab/nsp12	225	T225T	acC	acA	1	2	B.1.351	0.00003
ORF1ab/nsp12	225	T225T	acC	acT	1	2	B.1.351	0.00003
ORF1ab/nsp12	225	T225T	acC	acT	2	2	B.1.36.29	0.001035
ORF1ab/nsp12	225	T225T	acC	acT	2	2	B.1.525	0.000226
ORF1ab/nsp12	225	T225del	ACC	---	2	2	B.1.525	0.000226
ORF1ab/nsp12	225	T225T	acC	acT	2	2	B.1.576	0.001813
ORF1ab/nsp12	225	T225I	aCc	aTc	2	2	C.37	0.000232
ORF1ab/nsp12	225	T225N	aCc	aAc	2	2	P.1	0.000032
ORF1ab/nsp12	225	T225T	acC	acT	2	2	P.1.12	0.000968
ORF1ab/nsp12	225	T225T	acC	acT	2	2	P.1.14	0.000096
ORF1ab/nsp12	225	T225K	aCC	aAA	1	1		0.055556
ORF1ab/nsp12	225	T225E	ACC	GAA	1	1		0.055556
ORF1ab/nsp12	225	T225T	acC	acA	1	1	A	0.000387
ORF1ab/nsp12	225	T225S	Acc	Tcc	1	1	AF.1	0.037037
ORF1ab/nsp12	225	T225del1	acC	ac-	1	1	All	0
ORF1ab/nsp12	225	T225V	ACc	GTc	1	1	All	0
ORF1ab/nsp12	225	T225K	aCC	aAA	1	1	All	0
ORF1ab/nsp12	225	T225E	ACC	GAA	1	1	All	0
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.1	0.000396
ORF1ab/nsp12	225	T225T	acC	acA	1	1	AY.106	0.000335
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.118	0.000063
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.119	0.000035
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.12	0.000316
ORF1ab/nsp12	225	T225del	ACC	---	1	1	AY.120	0.000037
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.13	0.000161
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.16.1	0.00047
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.16.1	0.00047
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.23	0.00007
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	AY.25	0.000006
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	AY.26	0.000028
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.29	0.000016
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.33	0.000067
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.34.1	0.00051
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.39	0.000025
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.39.1	0.00004
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	AY.4.2.1	0.000149
ORF1ab/nsp12	225	T225T	acC	acA	1	1	AY.40	0.000964
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	AY.42	0.00004
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.44	0.000006
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.46.6	0.000072
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.46.6	0.000072
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.47	0.000031
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	AY.5	0.000021
ORF1ab/nsp12	225	T225del	ACC	---	1	1	AY.5.3	0.000337
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.5.4	0.000277
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.59	0.00053
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.59	0.00053
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	AY.61	0.000105
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.64	0.000595
ORF1ab/nsp12	225	T225del	ACC	---	1	1	AY.65	0.000533
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.67	0.000464
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.67	0.000464
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.7	0.000196
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.70	0.000209
ORF1ab/nsp12	225	T225T	acC	acA	1	1	AY.77	0.001127
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.8	0.000606
ORF1ab/nsp12	225	T225del	ACC	---	1	1	AY.8	0.000606
ORF1ab/nsp12	225	T225P	Acc	Ccc	1	1	AY.84	0.000437
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.85	0.000427
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.9	0.000068
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.9	0.000068
ORF1ab/nsp12	225	T225T	acC	acA	1	1	AY.95	0.000761
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AY.95	0.000761
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	AY.98.1	0.000048
ORF1ab/nsp12	225	T225T	acC	acT	1	1	AY.99.2	0.000092
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	AZ.2	0.000821
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B	0.000128
ORF1ab/nsp12	225	T225P	Acc	Ccc	1	1	B	0.000128
ORF1ab/nsp12	225	T225V	ACc	GTc	1	1	B.1	0.000009
ORF1ab/nsp12	225	T225P	Acc	Ccc	1	1	B.1	0.000009
ORF1ab/nsp12	225	T225del	ACC	---	1	1	B.1.1	0.000018
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B.1.1.1	0.000327
ORF1ab/nsp12	225	T225del	ACC	---	1	1	B.1.1.1	0.000327
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.1.1	0.000327
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.1.237	0.005405
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.1.298	0.000862
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.1.312	0.001912
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.1.33	0.000421
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.1.37	0.000193
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.1.4	0.002976
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B.1.1.409	0.002833
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.1.432	0.001266
ORF1ab/nsp12	225	T225P	Acc	Ccc	1	1	B.1.1.50	0.000679
ORF1ab/nsp12	225	T225del1	acC	ac-	1	1	B.1.1.7	0.000001
ORF1ab/nsp12	225	T225S	Acc	Tcc	1	1	B.1.1.7	0.000001
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.110.3	0.000718
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.159	0.012195
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.177.15	0.000631
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B.1.177.20	0.001517
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.177.33	0.001645
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.177.62	0.001192
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.177.73	0.000566
ORF1ab/nsp12	225	T225del	ACC	---	1	1	B.1.2	0.000009
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.2	0.000009
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.201	0.005682
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.221	0.000071
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.240	0.000216
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.243	0.00007
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.243	0.00007
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.258	0.000067
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.258	0.000067
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.311	0.000275
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.338	0.008621
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.1.351	0.00003
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	B.1.36.17	0.000494
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.382	0.008929
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.400	0.000429
ORF1ab/nsp12	225	T225P	Acc	Ccc	1	1	B.1.424	0.008065
ORF1ab/nsp12	225	T225S	Acc	Tcc	1	1	B.1.499	0.00105
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.544	0.006024
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.575	0.000303
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.609	0.000479
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B.1.617.1	0.000129
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B.1.621	0.000089
ORF1ab/nsp12	225	T225T	acC	acA	1	1	B.1.623	0.000536
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	B.1.628	0.000352
ORF1ab/nsp12	225	T225T	acC	acT	1	1	B.1.637	0.000073
ORF1ab/nsp12	225	T225A	Acc	Gcc	1	1	B.6.6	0.000889
ORF1ab/nsp12	225	T225N	aCc	aAc	1	1	C.14	0.004329
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	D.2	0.000075
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	P.1	0.000016
ORF1ab/nsp12	225	T225P	Acc	Ccc	1	1	P.1.1	0.000318
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	P.1.17	0.000162
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	P.2	0.000187
ORF1ab/nsp12	225	T225I	aCc	aTc	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.