CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 202

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12202V202VV4594VsyngtTgtC183890.48633914044-14046
ORF1ab/nsp12202V202VV4594VsyngtTgtA183720.39344314044-14046
ORF1ab/nsp12202V202VV4594VsyngtTgtG183220.12021914044-14046
ORF1ab/nsp12202V202AV4594AnonsyngTtgCt5252114044-14046
ORF1ab/nsp12202V202IV4594InonsynGttAtt4949114044-14046
ORF1ab/nsp12202V202delV4594deldelGTT---1818114044-14046
ORF1ab/nsp12202V202FV4594FnonsynGttTtt1414114044-14046
ORF1ab/nsp12202V202del1V4594del1delgTtg-t540.814044-14046
ORF1ab/nsp12202V202del1V4594del1delGtt-tt510.214044-14046
ORF1ab/nsp12202V202CV4594CnonsynGTtTGt44114044-14046
ORF1ab/nsp12202V202LV4594LnonsynGttCtt44114044-14046
ORF1ab/nsp12202V202GV4594GnonsyngTtgGt22114044-14046
ORF1ab/nsp12202V202del2V4594del2delgTTg--11114044-14046

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12202V202VgtTgtC89183All0.000017
ORF1ab/nsp12202V202VgtTgtA72183All0.000014
ORF1ab/nsp12202V202VgtTgtG22183All0.000004
ORF1ab/nsp12202V202AgTtgCt5252All0.00001
ORF1ab/nsp12202V202IGttAtt4949All0.000009
ORF1ab/nsp12202V202VgtTgtC2527AY.40.000039
ORF1ab/nsp12202V202VgtTgtA227AY.40.000003
ORF1ab/nsp12202V202VgtTgtA1119B.1.1.70.00001
ORF1ab/nsp12202V202VgtTgtC819B.1.1.70.000007
ORF1ab/nsp12202V202delGTT---1818All0.000003
ORF1ab/nsp12202V202VgtTgtA1717AY.340.001648
ORF1ab/nsp12202V202VgtTgtA1717B.1.4290.0004
ORF1ab/nsp12202V202FGttTtt1414All0.000003
ORF1ab/nsp12202V202AgTtgCt1313B.1.1.70.000012
ORF1ab/nsp12202V202VgtTgtG1212AY.30.000119
ORF1ab/nsp12202V202IGttAtt99AY.40.000014
ORF1ab/nsp12202V202AgTtgCt99B.1.177.620.010727
ORF1ab/nsp12202V202delGTT---88B.1.1.70.000007
ORF1ab/nsp12202V202VgtTgtC88B.1.2580.000532
ORF1ab/nsp12202V202VgtTgtA66AY.870.004996
ORF1ab/nsp12202V202AgTtgCt66B.1.617.20.000023
ORF1ab/nsp12202V202del1gTtg-t45All0.000001
ORF1ab/nsp12202V202del1Gtt-tt15All0
ORF1ab/nsp12202V202AgTtgCt55AY.1020.000133
ORF1ab/nsp12202V202IGttAtt55B.1.4760.5
ORF1ab/nsp12202V202VgtTgtC45B.1.617.20.000015
ORF1ab/nsp12202V202VgtTgtG15B.1.617.20.000004
ORF1ab/nsp12202V202CGTtTGt44All0.000001
ORF1ab/nsp12202V202LGttCtt44All0.000001
ORF1ab/nsp12202V202IGttAtt44AY.1030.000025
ORF1ab/nsp12202V202VgtTgtC44AY.140.000352
ORF1ab/nsp12202V202CGTtTGt44AY.30.00004
ORF1ab/nsp12202V202IGttAtt44AY.4.40.001637
ORF1ab/nsp12202V202VgtTgtA24AY.50.000041
ORF1ab/nsp12202V202VgtTgtC14AY.50.000021
ORF1ab/nsp12202V202VgtTgtG14AY.50.000021
ORF1ab/nsp12202V202AgTtgCt44AY.780.006163
ORF1ab/nsp12202V202FGttTtt44B.10.000037
ORF1ab/nsp12202V202VgtTgtC34B.10.000027
ORF1ab/nsp12202V202VgtTgtA14B.10.000009
ORF1ab/nsp12202V202IGttAtt44B.1.1770.000053
ORF1ab/nsp12202V202VgtTgtA24B.1.5260.000047
ORF1ab/nsp12202V202VgtTgtC24B.1.5260.000047
ORF1ab/nsp12202V202VgtTgtG33AY.200.000117
ORF1ab/nsp12202V202VgtTgtC33AY.46.40.000494
ORF1ab/nsp12202V202VgtTgtA33AY.610.000314
ORF1ab/nsp12202V202VgtTgtC33AY.750.000168
ORF1ab/nsp12202V202VgtTgtA23B.1.1600.000062
ORF1ab/nsp12202V202VgtTgtC13B.1.1600.000031
ORF1ab/nsp12202V202VgtTgtC23B.1.1770.000026
ORF1ab/nsp12202V202VgtTgtA13B.1.1770.000013
ORF1ab/nsp12202V202AgTtgCt33B.1.20.000026
ORF1ab/nsp12202V202VgtTgtC23B.1.20.000018
ORF1ab/nsp12202V202VgtTgtG13B.1.20.000009
ORF1ab/nsp12202V202GgTtgGt22All0
ORF1ab/nsp12202V202AgTtgCt22AY.1030.000012
ORF1ab/nsp12202V202IGttAtt22AY.250.000012
ORF1ab/nsp12202V202VgtTgtC22AY.300.000791
ORF1ab/nsp12202V202VgtTgtC22AY.390.000049
ORF1ab/nsp12202V202AgTtgCt22AY.40.000003
ORF1ab/nsp12202V202VgtTgtC22AY.4.20.000043
ORF1ab/nsp12202V202VgtTgtC22AY.420.00008
ORF1ab/nsp12202V202VgtTgtC22AY.430.000009
ORF1ab/nsp12202V202IGttAtt22AY.430.000009
ORF1ab/nsp12202V202IGttAtt22AY.680.000547
ORF1ab/nsp12202V202delGTT---22AY.990.002099
ORF1ab/nsp12202V202AgTtgCt22B.1.1.1700.002494
ORF1ab/nsp12202V202IGttAtt22B.1.1.70.000002
ORF1ab/nsp12202V202VgtTgtC22B.1.177.870.001456
ORF1ab/nsp12202V202IGttAtt22B.1.2580.000133
ORF1ab/nsp12202V202VgtTgtA22B.1.36.290.001035
ORF1ab/nsp12202V202IGttAtt22B.1.5090.001732
ORF1ab/nsp12202V202delGTT---22B.1.5250.000226
ORF1ab/nsp12202V202IGttAtt22B.1.617.20.000008
ORF1ab/nsp12202V202del1gTtg-t22B.1.6270.00404
ORF1ab/nsp12202V202FGttTtt11A.10.000282
ORF1ab/nsp12202V202del2gTTg--11All0
ORF1ab/nsp12202V202VgtTgtC11AY.1030.000006
ORF1ab/nsp12202V202VgtTgtC11AY.1060.000335
ORF1ab/nsp12202V202VgtTgtG11AY.1170.000085
ORF1ab/nsp12202V202VgtTgtC11AY.1180.000063
ORF1ab/nsp12202V202VgtTgtC11AY.1200.000037
ORF1ab/nsp12202V202IGttAtt11AY.1210.000135
ORF1ab/nsp12202V202IGttAtt11AY.16.10.00047
ORF1ab/nsp12202V202AgTtgCt11AY.250.000006
ORF1ab/nsp12202V202del2gTTg--11AY.250.000006
ORF1ab/nsp12202V202VgtTgtC11AY.290.000016
ORF1ab/nsp12202V202IGttAtt11AY.30.00001
ORF1ab/nsp12202V202del1Gtt-tt11AY.40.000002
ORF1ab/nsp12202V202FGttTtt11AY.420.00004
ORF1ab/nsp12202V202IGttAtt11AY.420.00004
ORF1ab/nsp12202V202AgTtgCt11AY.430.000004
ORF1ab/nsp12202V202LGttCtt11AY.440.000006
ORF1ab/nsp12202V202VgtTgtA11AY.540.000095
ORF1ab/nsp12202V202VgtTgtC11AY.570.000656
ORF1ab/nsp12202V202FGttTtt11AY.60.000041
ORF1ab/nsp12202V202delGTT---11AY.650.000533
ORF1ab/nsp12202V202FGttTtt11AY.650.000533
ORF1ab/nsp12202V202FGttTtt11AY.660.00107
ORF1ab/nsp12202V202IGttAtt11AY.690.000187
ORF1ab/nsp12202V202delGTT---11AY.90.000068
ORF1ab/nsp12202V202VgtTgtG11AY.99.20.000092
ORF1ab/nsp12202V202IGttAtt11AY.99.20.000092
ORF1ab/nsp12202V202FGttTtt11B0.000128
ORF1ab/nsp12202V202AgTtgCt11B0.000128
ORF1ab/nsp12202V202IGttAtt11B.10.000009
ORF1ab/nsp12202V202LGttCtt11B.10.000009
ORF1ab/nsp12202V202VgtTgtA11B.1.10.000018
ORF1ab/nsp12202V202LGttCtt11B.1.10.000018
ORF1ab/nsp12202V202delGTT---11B.1.1.10.000327
ORF1ab/nsp12202V202VgtTgtC11B.1.1.2140.000055
ORF1ab/nsp12202V202AgTtgCt11B.1.1.3150.008475
ORF1ab/nsp12202V202IGttAtt11B.1.1.370.000193
ORF1ab/nsp12202V202delGTT---11B.1.1.4090.002833
ORF1ab/nsp12202V202del1gTtg-t11B.1.160.110.005714
ORF1ab/nsp12202V202AgTtgCt11B.1.1770.000013
ORF1ab/nsp12202V202VgtTgtC11B.1.177.600.000218
ORF1ab/nsp12202V202GgTtgGt11B.1.20.000009
ORF1ab/nsp12202V202delGTT---11B.1.20.000009
ORF1ab/nsp12202V202FGttTtt11B.1.20.000009
ORF1ab/nsp12202V202FGttTtt11B.1.3330.010526
ORF1ab/nsp12202V202VgtTgtG11B.1.360.000146
ORF1ab/nsp12202V202VgtTgtC11B.1.36.160.001425
ORF1ab/nsp12202V202VgtTgtA11B.1.36.170.000494
ORF1ab/nsp12202V202FGttTtt11B.1.3960.000706
ORF1ab/nsp12202V202IGttAtt11B.1.4290.000024
ORF1ab/nsp12202V202VgtTgtC11B.1.4780.011765
ORF1ab/nsp12202V202VgtTgtG11B.1.5750.000303
ORF1ab/nsp12202V202del1gTtg-t11B.1.5960.000087
ORF1ab/nsp12202V202LGttCtt11B.1.6060.006024
ORF1ab/nsp12202V202GgTtgGt11B.1.617.20.000004
ORF1ab/nsp12202V202VgtTgtC11B.1.619.10.000641
ORF1ab/nsp12202V202VgtTgtA11B.1.6370.000073
ORF1ab/nsp12202V202FGttTtt11B.1.88.10.004808
ORF1ab/nsp12202V202delGTT---11B.340.013699
ORF1ab/nsp12202V202VgtTgtA11D.20.000075
ORF1ab/nsp12202V202VgtTgtA11P.10.000016
ORF1ab/nsp12202V202AgTtgCt11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.