CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 174

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12174V174IV4566InonsynGtaAta20542054113960-13962
ORF1ab/nsp12174V174VV4566VsyngtAgtG205420420.99415813960-13962
ORF1ab/nsp12174V174VV4566VsyngtAgtT205470.0034079813960-13962
ORF1ab/nsp12174V174VV4566VsyngtAgtC205450.0024342713960-13962
ORF1ab/nsp12174V174AV4566AnonsyngTagCa4141113960-13962
ORF1ab/nsp12174V174LV4566LnonsynGtaTta22200.90909113960-13962
ORF1ab/nsp12174V174LV4566LnonsynGtaCta2220.090909113960-13962
ORF1ab/nsp12174V174delV4566deldelGTA---1616113960-13962
ORF1ab/nsp12174V174del1V4566del1delgtAgt-12110.91666713960-13962
ORF1ab/nsp12174V174del1V4566del1delGta-ta1210.083333313960-13962
ORF1ab/nsp12174V174del2V4566del2delgTAg--430.7513960-13962
ORF1ab/nsp12174V174del2V4566del2delGTa--a410.2513960-13962
ORF1ab/nsp12174V174GV4566GnonsyngTagGa22113960-13962

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12174V174IGtaAta20542054All0.000393
ORF1ab/nsp12174V174VgtAgtG20422054All0.000391
ORF1ab/nsp12174V174VgtAgtT72054All0.000001
ORF1ab/nsp12174V174VgtAgtC52054All0.000001
ORF1ab/nsp12174V174VgtAgtG10951095AY.750.061345
ORF1ab/nsp12174V174IGtaAta518518B.1.4290.012188
ORF1ab/nsp12174V174IGtaAta464464B.1.617.20.001747
ORF1ab/nsp12174V174VgtAgtG303303AY.9.20.011129
ORF1ab/nsp12174V174IGtaAta203203AY.610.02127
ORF1ab/nsp12174V174VgtAgtG169170B.1.1.70.000151
ORF1ab/nsp12174V174VgtAgtT1170B.1.1.70.000001
ORF1ab/nsp12174V174VgtAgtG116118AY.40.000181
ORF1ab/nsp12174V174VgtAgtT1118AY.40.000002
ORF1ab/nsp12174V174VgtAgtC1118AY.40.000002
ORF1ab/nsp12174V174IGtaAta8888B.1.1.70.000079
ORF1ab/nsp12174V174IGtaAta8080B.10.000733
ORF1ab/nsp12174V174IGtaAta7878AY.40.000121
ORF1ab/nsp12174V174IGtaAta6464AY.60.002632
ORF1ab/nsp12174V174IGtaAta6363AY.75.10.01136
ORF1ab/nsp12174V174VgtAgtG6161AY.1030.000379
ORF1ab/nsp12174V174VgtAgtG6060B.1.1.2240.857143
ORF1ab/nsp12174V174AgTagCa4141All0.000008
ORF1ab/nsp12174V174IGtaAta3434AY.200.001321
ORF1ab/nsp12174V174IGtaAta3030B.1.2430.002088
ORF1ab/nsp12174V174IGtaAta2828AY.250.000168
ORF1ab/nsp12174V174IGtaAta2424B.1.5090.020779
ORF1ab/nsp12174V174IGtaAta2323AY.1130.003275
ORF1ab/nsp12174V174VgtAgtG2223B.1.617.20.000083
ORF1ab/nsp12174V174VgtAgtC123B.1.617.20.000004
ORF1ab/nsp12174V174LGtaTta2022All0.000004
ORF1ab/nsp12174V174LGtaCta222All0
ORF1ab/nsp12174V174IGtaAta2222AY.1180.001378
ORF1ab/nsp12174V174IGtaAta1818AY.440.00011
ORF1ab/nsp12174V174VgtAgtG1717AY.4.20.000369
ORF1ab/nsp12174V174delGTA---1616All0.000003
ORF1ab/nsp12174V174VgtAgtG1515AY.50.00031
ORF1ab/nsp12174V174IGtaAta1414AY.710.006651
ORF1ab/nsp12174V174VgtAgtG1414B.1.258.170.001456
ORF1ab/nsp12174V174IGtaAta1313AY.16.10.006109
ORF1ab/nsp12174V174del1gtAgt-1112All0.000002
ORF1ab/nsp12174V174del1Gta-ta112All0
ORF1ab/nsp12174V174IGtaAta1212AY.1160.003441
ORF1ab/nsp12174V174IGtaAta1212AY.430.000053
ORF1ab/nsp12174V174IGtaAta1111AY.1030.000068
ORF1ab/nsp12174V174VgtAgtG1011AY.250.00006
ORF1ab/nsp12174V174VgtAgtC111AY.250.000006
ORF1ab/nsp12174V174IGtaAta1111AY.30.000109
ORF1ab/nsp12174V174IGtaAta1111AY.390.000272
ORF1ab/nsp12174V174IGtaAta1111B.1.20.000097
ORF1ab/nsp12174V174VgtAgtG1010AY.540.000953
ORF1ab/nsp12174V174VgtAgtG1010B.1.1770.000132
ORF1ab/nsp12174V174IGtaAta1010B.1.3690.002852
ORF1ab/nsp12174V174VgtAgtG99AY.440.000055
ORF1ab/nsp12174V174VgtAgtG78B.1.5250.000792
ORF1ab/nsp12174V174VgtAgtT18B.1.5250.000113
ORF1ab/nsp12174V174IGtaAta88B.1.5260.000188
ORF1ab/nsp12174V174IGtaAta88P.10.000126
ORF1ab/nsp12174V174IGtaAta77AY.1020.000186
ORF1ab/nsp12174V174AgTagCa77B.1.1.2980.006034
ORF1ab/nsp12174V174VgtAgtG77B.1.20.000062
ORF1ab/nsp12174V174IGtaAta66AY.1110.001099
ORF1ab/nsp12174V174IGtaAta66AY.130.000966
ORF1ab/nsp12174V174VgtAgtG66AY.390.000148
ORF1ab/nsp12174V174IGtaAta66AY.470.000187
ORF1ab/nsp12174V174IGtaAta66AY.700.001251
ORF1ab/nsp12174V174IGtaAta66AY.970.010204
ORF1ab/nsp12174V174VgtAgtG66B.10.000055
ORF1ab/nsp12174V174del1gtAgt-66B.1.1.3690.002677
ORF1ab/nsp12174V174AgTagCa66B.1.1.70.000005
ORF1ab/nsp12174V174IGtaAta66B.1.5170.002562
ORF1ab/nsp12174V174IGtaAta66B.1.5960.000523
ORF1ab/nsp12174V174VgtAgtG55A0.001935
ORF1ab/nsp12174V174IGtaAta55AY.1100.000563
ORF1ab/nsp12174V174IGtaAta55AY.1190.000177
ORF1ab/nsp12174V174IGtaAta55AY.140.00044
ORF1ab/nsp12174V174IGtaAta55AY.750.00028
ORF1ab/nsp12174V174IGtaAta55AY.9.20.000184
ORF1ab/nsp12174V174IGtaAta55AY.980.000395
ORF1ab/nsp12174V174IGtaAta55B0.000639
ORF1ab/nsp12174V174VgtAgtG55B.1.177.600.001092
ORF1ab/nsp12174V174IGtaAta55B.1.6370.000365
ORF1ab/nsp12174V174del2gTAg--34All0.000001
ORF1ab/nsp12174V174del2GTa--a14All0
ORF1ab/nsp12174V174VgtAgtG44AY.1130.00057
ORF1ab/nsp12174V174VgtAgtG44AY.200.000155
ORF1ab/nsp12174V174IGtaAta44AY.260.000113
ORF1ab/nsp12174V174VgtAgtG44AY.290.000063
ORF1ab/nsp12174V174IGtaAta44AY.39.10.000158
ORF1ab/nsp12174V174IGtaAta44AY.420.000161
ORF1ab/nsp12174V174IGtaAta44AY.460.000416
ORF1ab/nsp12174V174IGtaAta44AY.670.001857
ORF1ab/nsp12174V174AgTagCa44B.1.10.000073
ORF1ab/nsp12174V174delGTA---44B.1.1.70.000004
ORF1ab/nsp12174V174IGtaAta44B.1.3510.000119
ORF1ab/nsp12174V174VgtAgtG44B.1.5680.004444
ORF1ab/nsp12174V174AgTagCa44B.1.617.20.000015
ORF1ab/nsp12174V174IGtaAta33AD.20.000657
ORF1ab/nsp12174V174IGtaAta33AY.1000.000138
ORF1ab/nsp12174V174VgtAgtG33AY.1180.000188
ORF1ab/nsp12174V174IGtaAta33AY.160.001139
ORF1ab/nsp12174V174IGtaAta33AY.230.000209
ORF1ab/nsp12174V174VgtAgtG33AY.30.00003
ORF1ab/nsp12174V174IGtaAta33AY.330.0002
ORF1ab/nsp12174V174LGtaTta33AY.390.000074
ORF1ab/nsp12174V174VgtAgtG23AY.430.000009
ORF1ab/nsp12174V174VgtAgtT13AY.430.000004
ORF1ab/nsp12174V174IGtaAta33AY.650.001599
ORF1ab/nsp12174V174VgtAgtG23AY.75.10.000361
ORF1ab/nsp12174V174VgtAgtC13AY.75.10.00018
ORF1ab/nsp12174V174IGtaAta33AY.98.10.000145
ORF1ab/nsp12174V174VgtAgtG23B.1.10.000036
ORF1ab/nsp12174V174VgtAgtT13B.1.10.000018
ORF1ab/nsp12174V174LGtaTta23B.1.1.70.000002
ORF1ab/nsp12174V174LGtaCta13B.1.1.70.000001
ORF1ab/nsp12174V174AgTagCa33B.1.20.000026
ORF1ab/nsp12174V174VgtAgtG33B.1.2210.000213
ORF1ab/nsp12174V174IGtaAta33B.1.2580.0002
ORF1ab/nsp12174V174LGtaTta33B.1.258.170.000312
ORF1ab/nsp12174V174VgtAgtG33B.1.5880.00273
ORF1ab/nsp12174V174LGtaTta33B.1.617.20.000011
ORF1ab/nsp12174V174GgTagGa22All0
ORF1ab/nsp12174V174VgtAgtG22AY.1170.000169
ORF1ab/nsp12174V174VgtAgtG22AY.1200.000074
ORF1ab/nsp12174V174IGtaAta22AY.1200.000074
ORF1ab/nsp12174V174VgtAgtG22AY.140.000176
ORF1ab/nsp12174V174VgtAgtG22AY.260.000057
ORF1ab/nsp12174V174IGtaAta22AY.290.000032
ORF1ab/nsp12174V174VgtAgtG22AY.300.000791
ORF1ab/nsp12174V174AgTagCa22AY.40.000003
ORF1ab/nsp12174V174IGtaAta22AY.50.000041
ORF1ab/nsp12174V174IGtaAta22AY.520.001629
ORF1ab/nsp12174V174IGtaAta22AY.600.001876
ORF1ab/nsp12174V174IGtaAta22AY.620.000871
ORF1ab/nsp12174V174VgtAgtG22AY.620.000871
ORF1ab/nsp12174V174VgtAgtG22AY.850.000854
ORF1ab/nsp12174V174VgtAgtG22AY.980.000158
ORF1ab/nsp12174V174LGtaTta22B.10.000018
ORF1ab/nsp12174V174VgtAgtG22B.1.1.2140.000111
ORF1ab/nsp12174V174VgtAgtG22B.1.1.2840.000215
ORF1ab/nsp12174V174IGtaAta22B.1.1.3480.001592
ORF1ab/nsp12174V174del2gTAg--22B.1.1.70.000002
ORF1ab/nsp12174V174VgtAgtG22B.1.177.100.001756
ORF1ab/nsp12174V174VgtAgtT22B.1.177.450.000762
ORF1ab/nsp12174V174VgtAgtG22B.1.3510.000059
ORF1ab/nsp12174V174VgtAgtG22B.1.360.000292
ORF1ab/nsp12174V174VgtAgtG22B.1.36.290.001035
ORF1ab/nsp12174V174IGtaAta22B.1.617.10.000258
ORF1ab/nsp12174V174IGtaAta22B.1.6210.000177
ORF1ab/nsp12174V174VgtAgtG22D.20.00015
ORF1ab/nsp12174V174AgTagCa22P.10.000032
ORF1ab/nsp12174V174VgtAgtG22P.10.000032
ORF1ab/nsp12174V174delGTA---22Q.10.000253
ORF1ab/nsp12174V174IGtaAta11A0.000387
ORF1ab/nsp12174V174IGtaAta11A.2.40.003367
ORF1ab/nsp12174V174IGtaAta11AU.20.002421
ORF1ab/nsp12174V174VgtAgtG11AY.1000.000046
ORF1ab/nsp12174V174VgtAgtG11AY.1010.00049
ORF1ab/nsp12174V174VgtAgtG11AY.1020.000027
ORF1ab/nsp12174V174AgTagCa11AY.1100.000113
ORF1ab/nsp12174V174IGtaAta11AY.1170.000085
ORF1ab/nsp12174V174VgtAgtG11AY.1190.000035
ORF1ab/nsp12174V174VgtAgtG11AY.120.000316
ORF1ab/nsp12174V174VgtAgtG11AY.1210.000135
ORF1ab/nsp12174V174LGtaTta11AY.140.000088
ORF1ab/nsp12174V174IGtaAta11AY.190.00114
ORF1ab/nsp12174V174VgtAgtG11AY.240.000431
ORF1ab/nsp12174V174LGtaTta11AY.250.000006
ORF1ab/nsp12174V174AgTagCa11AY.250.000006
ORF1ab/nsp12174V174LGtaTta11AY.260.000028
ORF1ab/nsp12174V174IGtaAta11AY.270.000065
ORF1ab/nsp12174V174IGtaAta11AY.29.10.000221
ORF1ab/nsp12174V174IGtaAta11AY.300.000396
ORF1ab/nsp12174V174IGtaAta11AY.340.000097
ORF1ab/nsp12174V174IGtaAta11AY.34.10.00051
ORF1ab/nsp12174V174VgtAgtC11AY.350.000233
ORF1ab/nsp12174V174IGtaAta11AY.350.000233
ORF1ab/nsp12174V174IGtaAta11AY.360.000148
ORF1ab/nsp12174V174IGtaAta11AY.370.000316
ORF1ab/nsp12174V174IGtaAta11AY.4.20.000022
ORF1ab/nsp12174V174AgTagCa11AY.420.00004
ORF1ab/nsp12174V174del1gtAgt-11AY.430.000004
ORF1ab/nsp12174V174LGtaTta11AY.440.000006
ORF1ab/nsp12174V174del2GTa--a11AY.440.000006
ORF1ab/nsp12174V174AgTagCa11AY.440.000006
ORF1ab/nsp12174V174IGtaAta11AY.46.50.000198
ORF1ab/nsp12174V174VgtAgtG11AY.470.000031
ORF1ab/nsp12174V174VgtAgtG11AY.5.40.000277
ORF1ab/nsp12174V174IGtaAta11AY.530.000288
ORF1ab/nsp12174V174AgTagCa11AY.540.000095
ORF1ab/nsp12174V174VgtAgtG11AY.60.000041
ORF1ab/nsp12174V174VgtAgtG11AY.640.000595
ORF1ab/nsp12174V174VgtAgtG11AY.650.000533
ORF1ab/nsp12174V174LGtaTta11AY.670.000464
ORF1ab/nsp12174V174VgtAgtG11AY.680.000274
ORF1ab/nsp12174V174IGtaAta11AY.740.000116
ORF1ab/nsp12174V174delGTA---11AY.750.000056
ORF1ab/nsp12174V174IGtaAta11AY.820.001357
ORF1ab/nsp12174V174IGtaAta11AY.830.001724
ORF1ab/nsp12174V174IGtaAta11AY.90.000068
ORF1ab/nsp12174V174AgTagCa11AY.9.20.000037
ORF1ab/nsp12174V174delGTA---11AY.990.001049
ORF1ab/nsp12174V174IGtaAta11AY.99.20.000092
ORF1ab/nsp12174V174VgtAgtG11AY.99.20.000092
ORF1ab/nsp12174V174delGTA---11B0.000128
ORF1ab/nsp12174V174del1gtAgt-11B.10.000009
ORF1ab/nsp12174V174IGtaAta11B.1.10.000018
ORF1ab/nsp12174V174GgTagGa11B.1.10.000018
ORF1ab/nsp12174V174del1gtAgt-11B.1.10.000018
ORF1ab/nsp12174V174delGTA---11B.1.1.10.000327
ORF1ab/nsp12174V174delGTA---11B.1.1.1390.022727
ORF1ab/nsp12174V174VgtAgtG11B.1.1.1760.000439
ORF1ab/nsp12174V174IGtaAta11B.1.1.2220.000204
ORF1ab/nsp12174V174IGtaAta11B.1.1.2290.005747
ORF1ab/nsp12174V174VgtAgtG11B.1.1.2940.001266
ORF1ab/nsp12174V174LGtaTta11B.1.1.3170.000412
ORF1ab/nsp12174V174delGTA---11B.1.1.3480.000796
ORF1ab/nsp12174V174IGtaAta11B.1.1.3510.002793
ORF1ab/nsp12174V174IGtaAta11B.1.1.3700.012658
ORF1ab/nsp12174V174VgtAgtG11B.1.1.390.00051
ORF1ab/nsp12174V174delGTA---11B.1.1.4340.000349
ORF1ab/nsp12174V174IGtaAta11B.1.1.4850.016667
ORF1ab/nsp12174V174AgTagCa11B.1.1.510.001718
ORF1ab/nsp12174V174IGtaAta11B.1.1600.000031
ORF1ab/nsp12174V174IGtaAta11B.1.1770.000013
ORF1ab/nsp12174V174AgTagCa11B.1.1770.000013
ORF1ab/nsp12174V174delGTA---11B.1.1770.000013
ORF1ab/nsp12174V174VgtAgtG11B.1.177.70.000165
ORF1ab/nsp12174V174VgtAgtG11B.1.177.790.002342
ORF1ab/nsp12174V174VgtAgtG11B.1.177.850.005435
ORF1ab/nsp12174V174IGtaAta11B.1.2060.000816
ORF1ab/nsp12174V174VgtAgtG11B.1.214.20.0006
ORF1ab/nsp12174V174IGtaAta11B.1.2340.000132
ORF1ab/nsp12174V174AgTagCa11B.1.2390.001221
ORF1ab/nsp12174V174VgtAgtG11B.1.2580.000067
ORF1ab/nsp12174V174del1gtAgt-11B.1.350.008475
ORF1ab/nsp12174V174AgTagCa11B.1.3510.00003
ORF1ab/nsp12174V174GgTagGa11B.1.36.290.000517
ORF1ab/nsp12174V174VgtAgtG11B.1.36.80.001
ORF1ab/nsp12174V174AgTagCa11B.1.4290.000024
ORF1ab/nsp12174V174VgtAgtG11B.1.4290.000024
ORF1ab/nsp12174V174IGtaAta11B.1.4530.003236
ORF1ab/nsp12174V174IGtaAta11B.1.5240.001406
ORF1ab/nsp12174V174del2gTAg--11B.1.5250.000113
ORF1ab/nsp12174V174AgTagCa11B.1.5260.000024
ORF1ab/nsp12174V174IGtaAta11B.1.5820.000491
ORF1ab/nsp12174V174VgtAgtG11B.1.5820.000491
ORF1ab/nsp12174V174VgtAgtG11B.1.595.40.007299
ORF1ab/nsp12174V174del1Gta-ta11B.1.5960.000087
ORF1ab/nsp12174V174AgTagCa11B.1.617.10.000129
ORF1ab/nsp12174V174del1gtAgt-11B.1.617.10.000129
ORF1ab/nsp12174V174VgtAgtG11B.1.6210.000089
ORF1ab/nsp12174V174delGTA---11B.340.013699
ORF1ab/nsp12174V174IGtaAta11B.400.000364
ORF1ab/nsp12174V174delGTA---11B.550.00295
ORF1ab/nsp12174V174VgtAgtG11C.370.000116
ORF1ab/nsp12174V174LGtaTta11D.20.000075
ORF1ab/nsp12174V174IGtaAta11N.80.03125
ORF1ab/nsp12174V174LGtaCta11P.10.000016
ORF1ab/nsp12174V174IGtaAta11P.1.10.000318
ORF1ab/nsp12174V174IGtaAta11P.1.150.000232
ORF1ab/nsp12174V174IGtaAta11P.1.160.000374
ORF1ab/nsp12174V174VgtAgtG11P.1.70.000319
ORF1ab/nsp12174V174IGtaAta11P.20.000187
ORF1ab/nsp12174V174IGtaAta11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.