CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 137

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12137G137GG4529GsynggTggC302930200.99702913849-13851
ORF1ab/nsp12137G137GG4529GsynggTggG302950.0016507113849-13851
ORF1ab/nsp12137G137GG4529GsynggTggA302940.0013205713849-13851
ORF1ab/nsp12137G137VG4529VnonsyngGtgTt450450113849-13851
ORF1ab/nsp12137G137CG4529CnonsynGgtTgt270270113849-13851
ORF1ab/nsp12137G137SG4529SnonsynGgtAgt194194113849-13851
ORF1ab/nsp12137G137DG4529DnonsyngGtgAt51500.98039213849-13851
ORF1ab/nsp12137G137DG4529DnonsyngGTgAC5110.019607813849-13851
ORF1ab/nsp12137G137delG4529deldelGGT---77113849-13851
ORF1ab/nsp12137G137RG4529RnonsynGgtCgt44113849-13851
ORF1ab/nsp12137G137WG4529WnonsynGgTTgG22113849-13851
ORF1ab/nsp12137G137XG4529XnonsynGgTTgA11113849-13851
ORF1ab/nsp12137G137NG4529NnonsynGGtAAt11113849-13851
ORF1ab/nsp12137G137YG4529YnonsynGGTTAC11113849-13851

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12137G137GggTggC30203029All0.000578
ORF1ab/nsp12137G137GggTggG53029All0.000001
ORF1ab/nsp12137G137GggTggA43029All0.000001
ORF1ab/nsp12137G137GggTggC28812881P.1.10.915184
ORF1ab/nsp12137G137VgGtgTt450450All0.000086
ORF1ab/nsp12137G137CGgtTgt270270All0.000052
ORF1ab/nsp12137G137SGgtAgt194194All0.000037
ORF1ab/nsp12137G137CGgtTgt143143B.1.1.4130.986207
ORF1ab/nsp12137G137VgGtgTt122122AY.340.01183
ORF1ab/nsp12137G137VgGtgTt8585AY.1000.003911
ORF1ab/nsp12137G137VgGtgTt7171AY.40.000111
ORF1ab/nsp12137G137VgGtgTt5858B.1.617.20.000218
ORF1ab/nsp12137G137DgGtgAt5051All0.00001
ORF1ab/nsp12137G137DgGTgAC151All0
ORF1ab/nsp12137G137SGgtAgt4444B.1.1.70.000039
ORF1ab/nsp12137G137GggTggC4344B.1.1.70.000038
ORF1ab/nsp12137G137GggTggA144B.1.1.70.000001
ORF1ab/nsp12137G137SGgtAgt3636AY.30.000358
ORF1ab/nsp12137G137SGgtAgt2828AY.250.000168
ORF1ab/nsp12137G137CGgtTgt2222B.1.1.70.00002
ORF1ab/nsp12137G137CGgtTgt1717B.10.000156
ORF1ab/nsp12137G137GggTggC1616AS.20.25
ORF1ab/nsp12137G137SGgtAgt1515AY.9.20.000551
ORF1ab/nsp12137G137CGgtTgt1515B.1.20.000132
ORF1ab/nsp12137G137VgGtgTt1414AY.9.10.001172
ORF1ab/nsp12137G137CGgtTgt1414B.1.10.000254
ORF1ab/nsp12137G137SGgtAgt1313B.1.3510.000386
ORF1ab/nsp12137G137SGgtAgt1212B.1.1.2840.001289
ORF1ab/nsp12137G137GggTggC1212P.10.000189
ORF1ab/nsp12137G137DgGtgAt99AY.40.000014
ORF1ab/nsp12137G137VgGtgTt99B.1.2580.000599
ORF1ab/nsp12137G137GggTggC88B.10.000073
ORF1ab/nsp12137G137DgGtgAt88B.1.1.3050.030888
ORF1ab/nsp12137G137delGGT---77All0.000001
ORF1ab/nsp12137G137GggTggC77AY.250.000042
ORF1ab/nsp12137G137VgGtgTt77B.1.1600.000218
ORF1ab/nsp12137G137GggTggC77B.1.2210.000497
ORF1ab/nsp12137G137VgGtgTt66AY.250.000036
ORF1ab/nsp12137G137DgGtgAt66AY.430.000027
ORF1ab/nsp12137G137VgGtgTt66AY.46.60.000433
ORF1ab/nsp12137G137VgGtgTt66B.1.1.470.032086
ORF1ab/nsp12137G137VgGtgTt66D.20.00045
ORF1ab/nsp12137G137CGgtTgt55AY.40.000008
ORF1ab/nsp12137G137GggTggC55AY.4.40.002046
ORF1ab/nsp12137G137VgGtgTt55AY.440.00003
ORF1ab/nsp12137G137GggTggC45B.1.10.000073
ORF1ab/nsp12137G137GggTggG15B.1.10.000018
ORF1ab/nsp12137G137VgGtgTt55B.1.177.670.038168
ORF1ab/nsp12137G137GggTggG440.222222
ORF1ab/nsp12137G137RGgtCgt44All0.000001
ORF1ab/nsp12137G137VgGtgTt44AY.1020.000106
ORF1ab/nsp12137G137VgGtgTt44AY.1030.000025
ORF1ab/nsp12137G137SGgtAgt44AY.40.000006
ORF1ab/nsp12137G137CGgtTgt44AY.650.002132
ORF1ab/nsp12137G137SGgtAgt44B.1.177.800.007648
ORF1ab/nsp12137G137VgGtgTt44B.1.2210.000284
ORF1ab/nsp12137G137DgGtgAt44B.1.2430.000278
ORF1ab/nsp12137G137DgGtgAt34B.1.617.20.000011
ORF1ab/nsp12137G137DgGTgAC14B.1.617.20.000004
ORF1ab/nsp12137G137SGgtAgt33AY.1030.000019
ORF1ab/nsp12137G137GggTggC33AY.330.0002
ORF1ab/nsp12137G137CGgtTgt33AY.440.000018
ORF1ab/nsp12137G137GggTggC33AY.470.000093
ORF1ab/nsp12137G137DgGtgAt33AY.740.000347
ORF1ab/nsp12137G137DgGtgAt33B.1.1.3540.013158
ORF1ab/nsp12137G137RGgtCgt33B.1.1.70.000003
ORF1ab/nsp12137G137CGgtTgt33B.1.4270.000151
ORF1ab/nsp12137G137VgGtgTt33B.1.4700.004213
ORF1ab/nsp12137G137SGgtAgt33B.1.5260.000071
ORF1ab/nsp12137G137SGgtAgt33B.1.617.20.000011
ORF1ab/nsp12137G137GggTggC33B.1.617.20.000011
ORF1ab/nsp12137G137WGgTTgG220.111111
ORF1ab/nsp12137G137WGgTTgG22All0
ORF1ab/nsp12137G137SGgtAgt22AY.1180.000125
ORF1ab/nsp12137G137GggTggC22AY.120.2.10.000997
ORF1ab/nsp12137G137CGgtTgt22AY.160.000759
ORF1ab/nsp12137G137SGgtAgt22AY.200.000078
ORF1ab/nsp12137G137CGgtTgt22AY.250.000012
ORF1ab/nsp12137G137DgGtgAt22AY.30.00002
ORF1ab/nsp12137G137CGgtTgt22AY.330.000134
ORF1ab/nsp12137G137CGgtTgt22AY.360.000296
ORF1ab/nsp12137G137GggTggC22AY.390.000049
ORF1ab/nsp12137G137GggTggC22AY.40.000003
ORF1ab/nsp12137G137CGgtTgt22AY.430.000009
ORF1ab/nsp12137G137SGgtAgt22AY.440.000012
ORF1ab/nsp12137G137SGgtAgt22AY.46.60.000144
ORF1ab/nsp12137G137VgGtgTt22AY.740.000231
ORF1ab/nsp12137G137VgGtgTt22AY.840.000875
ORF1ab/nsp12137G137GggTggC22AY.98.10.000097
ORF1ab/nsp12137G137SGgtAgt22AY.99.20.000184
ORF1ab/nsp12137G137CGgtTgt22B0.000256
ORF1ab/nsp12137G137SGgtAgt22B.10.000018
ORF1ab/nsp12137G137VgGtgTt22B.10.000018
ORF1ab/nsp12137G137VgGtgTt22B.1.1.10.000653
ORF1ab/nsp12137G137CGgtTgt22B.1.1.280.000622
ORF1ab/nsp12137G137DgGtgAt22B.1.1.70.000002
ORF1ab/nsp12137G137VgGtgTt22B.1.1.70.000002
ORF1ab/nsp12137G137VgGtgTt22B.1.1770.000026
ORF1ab/nsp12137G137GggTggC22B.1.1770.000026
ORF1ab/nsp12137G137GggTggC22B.1.20.000018
ORF1ab/nsp12137G137SGgtAgt22B.1.20.000018
ORF1ab/nsp12137G137VgGtgTt22B.1.2390.002442
ORF1ab/nsp12137G137CGgtTgt22B.1.2580.000133
ORF1ab/nsp12137G137CGgtTgt22B.1.2600.006689
ORF1ab/nsp12137G137CGgtTgt22B.1.264.10.095238
ORF1ab/nsp12137G137GggTggC22B.1.3510.000059
ORF1ab/nsp12137G137SGgtAgt22B.1.36.290.001035
ORF1ab/nsp12137G137GggTggC22B.1.5960.000174
ORF1ab/nsp12137G137CGgtTgt22B.1.617.20.000008
ORF1ab/nsp12137G137DgGtgAt22B.1.6370.000146
ORF1ab/nsp12137G137SGgtAgt22P.10.000032
ORF1ab/nsp12137G137CGgtTgt11A0.000387
ORF1ab/nsp12137G137GggTggC11A.10.000282
ORF1ab/nsp12137G137NGGtAAt11All0
ORF1ab/nsp12137G137YGGTTAC11All0
ORF1ab/nsp12137G137XGgTTgA11All0
ORF1ab/nsp12137G137CGgtTgt11AY.1020.000027
ORF1ab/nsp12137G137delGGT---11AY.1200.000037
ORF1ab/nsp12137G137VgGtgTt11AY.1210.000135
ORF1ab/nsp12137G137delGGT---11AY.250.000006
ORF1ab/nsp12137G137SGgtAgt11AY.260.000028
ORF1ab/nsp12137G137SGgtAgt11AY.290.000016
ORF1ab/nsp12137G137GggTggC11AY.30.00001
ORF1ab/nsp12137G137DgGtgAt11AY.300.000396
ORF1ab/nsp12137G137CGgtTgt11AY.340.000097
ORF1ab/nsp12137G137VgGtgTt11AY.390.000025
ORF1ab/nsp12137G137CGgtTgt11AY.390.000025
ORF1ab/nsp12137G137CGgtTgt11AY.39.10.00004
ORF1ab/nsp12137G137SGgtAgt11AY.39.10.00004
ORF1ab/nsp12137G137GggTggC11AY.420.00004
ORF1ab/nsp12137G137VgGtgTt11AY.420.00004
ORF1ab/nsp12137G137VgGtgTt11AY.430.000004
ORF1ab/nsp12137G137GggTggC11AY.440.000006
ORF1ab/nsp12137G137DgGtgAt11AY.440.000006
ORF1ab/nsp12137G137CGgtTgt11AY.450.000122
ORF1ab/nsp12137G137VgGtgTt11AY.50.000021
ORF1ab/nsp12137G137SGgtAgt11AY.5.30.000337
ORF1ab/nsp12137G137CGgtTgt11AY.550.000917
ORF1ab/nsp12137G137DgGtgAt11AY.550.000917
ORF1ab/nsp12137G137CGgtTgt11AY.570.000656
ORF1ab/nsp12137G137SGgtAgt11AY.60.000041
ORF1ab/nsp12137G137GggTggC11AY.610.000105
ORF1ab/nsp12137G137CGgtTgt11AY.710.000475
ORF1ab/nsp12137G137CGgtTgt11AY.850.000427
ORF1ab/nsp12137G137CGgtTgt11AY.980.000079
ORF1ab/nsp12137G137XGgTTgA11B0.000128
ORF1ab/nsp12137G137SGgtAgt11B0.000128
ORF1ab/nsp12137G137GggTggA11B0.000128
ORF1ab/nsp12137G137VgGtgTt11B0.000128
ORF1ab/nsp12137G137delGGT---11B.1.1.10.000327
ORF1ab/nsp12137G137delGGT---11B.1.1.1390.022727
ORF1ab/nsp12137G137VgGtgTt11B.1.1.1530.001095
ORF1ab/nsp12137G137CGgtTgt11B.1.1.1740.003378
ORF1ab/nsp12137G137VgGtgTt11B.1.1.1760.000439
ORF1ab/nsp12137G137delGGT---11B.1.1.2360.006897
ORF1ab/nsp12137G137CGgtTgt11B.1.1.3170.000412
ORF1ab/nsp12137G137CGgtTgt11B.1.1.3260.001761
ORF1ab/nsp12137G137delGGT---11B.1.1.3480.000796
ORF1ab/nsp12137G137GggTggC11B.1.1.3740.002375
ORF1ab/nsp12137G137VgGtgTt11B.1.1.5190.00004
ORF1ab/nsp12137G137GggTggC11B.1.1.5190.00004
ORF1ab/nsp12137G137CGgtTgt11B.1.1.5230.001563
ORF1ab/nsp12137G137delGGT---11B.1.1.70.000001
ORF1ab/nsp12137G137CGgtTgt11B.1.1.990.02381
ORF1ab/nsp12137G137DgGtgAt11B.1.1600.000031
ORF1ab/nsp12137G137SGgtAgt11B.1.1770.000013
ORF1ab/nsp12137G137CGgtTgt11B.1.1770.000013
ORF1ab/nsp12137G137GggTggC11B.1.177.160.000664
ORF1ab/nsp12137G137GggTggA11B.1.177.440.000519
ORF1ab/nsp12137G137VgGtgTt11B.1.177.810.000189
ORF1ab/nsp12137G137VgGtgTt11B.1.177.830.001481
ORF1ab/nsp12137G137VgGtgTt11B.1.177.870.000728
ORF1ab/nsp12137G137VgGtgTt11B.1.1890.004292
ORF1ab/nsp12137G137SGgtAgt11B.1.1950.005025
ORF1ab/nsp12137G137VgGtgTt11B.1.20.000009
ORF1ab/nsp12137G137YGGTTAC11B.1.20.000009
ORF1ab/nsp12137G137DgGtgAt11B.1.2210.000071
ORF1ab/nsp12137G137VgGtgTt11B.1.2430.00007
ORF1ab/nsp12137G137GggTggC11B.1.258.120.007874
ORF1ab/nsp12137G137VgGtgTt11B.1.258.170.000104
ORF1ab/nsp12137G137GggTggC11B.1.3490.000715
ORF1ab/nsp12137G137VgGtgTt11B.1.3510.00003
ORF1ab/nsp12137G137CGgtTgt11B.1.351.20.000303
ORF1ab/nsp12137G137SGgtAgt11B.1.360.000146
ORF1ab/nsp12137G137VgGtgTt11B.1.36.160.001425
ORF1ab/nsp12137G137VgGtgTt11B.1.4340.052632
ORF1ab/nsp12137G137DgGtgAt11B.1.438.10.000107
ORF1ab/nsp12137G137RGgtCgt11B.1.4560.003268
ORF1ab/nsp12137G137SGgtAgt11B.1.4970.000315
ORF1ab/nsp12137G137CGgtTgt11B.1.5260.000024
ORF1ab/nsp12137G137VgGtgTt11B.1.5260.000024
ORF1ab/nsp12137G137GggTggC11B.1.5260.000024
ORF1ab/nsp12137G137CGgtTgt11B.1.5330.009615
ORF1ab/nsp12137G137DgGtgAt11B.1.5820.000491
ORF1ab/nsp12137G137CGgtTgt11B.1.5950.000261
ORF1ab/nsp12137G137VgGtgTt11B.1.5960.000087
ORF1ab/nsp12137G137DgGtgAt11B.1.6120.002653
ORF1ab/nsp12137G137SGgtAgt11B.1.6300.005236
ORF1ab/nsp12137G137GggTggC11B.1.6360.006711
ORF1ab/nsp12137G137GggTggA11B.340.013699
ORF1ab/nsp12137G137CGgtTgt11P.10.000016
ORF1ab/nsp12137G137NGGtAAt11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.