CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp12 : CodonNum = 115

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp12115S115SS4507SsyntcAtcG5785530.95674713783-13785
ORF1ab/nsp12115S115SS4507SsyntcAtcT578200.034602113783-13785
ORF1ab/nsp12115S115SS4507SsyntcAtcC57850.0086505213783-13785
ORF1ab/nsp12115S115AS4507AnonsynTcaGca1171150.98290613783-13785
ORF1ab/nsp12115S115AS4507AnonsynTcAGcT11720.01709413783-13785
ORF1ab/nsp12115S115del1S4507del1deltCat-a5858113783-13785
ORF1ab/nsp12115S115delS4507deldelTCA---2626113783-13785
ORF1ab/nsp12115S115PS4507PnonsynTcaCca18150.83333313783-13785
ORF1ab/nsp12115S115PS4507PnonsynTcACcT1820.11111113783-13785
ORF1ab/nsp12115S115PS4507PnonsynTcACcG1810.055555613783-13785
ORF1ab/nsp12115S115XS4507XnonsyntCatAa1080.813783-13785
ORF1ab/nsp12115S115XS4507XnonsyntCatGa1020.213783-13785
ORF1ab/nsp12115S115LS4507LnonsyntCatTa640.66666713783-13785
ORF1ab/nsp12115S115LS4507LnonsynTCACTT620.33333313783-13785
ORF1ab/nsp12115S115TS4507TnonsynTcaAca33113783-13785
ORF1ab/nsp12115S115RS4507RnonsynTCaCGa11113783-13785
ORF1ab/nsp12115S115FS4507FnonsyntCAtTT11113783-13785
ORF1ab/nsp12115S115IS4507InonsynTCaATa11113783-13785

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp12115S115StcAtcG553578All0.000106
ORF1ab/nsp12115S115StcAtcT20578All0.000004
ORF1ab/nsp12115S115StcAtcC5578All0.000001
ORF1ab/nsp12115S115StcAtcG482482B.1.5260.011329
ORF1ab/nsp12115S115ATcaGca115117All0.000022
ORF1ab/nsp12115S115ATcAGcT2117All0
ORF1ab/nsp12115S115del1tCat-a5858All0.000011
ORF1ab/nsp12115S115ATcaGca5252AY.50.001074
ORF1ab/nsp12115S115del1tCat-a4747B.1.1.70.000042
ORF1ab/nsp12115S115delTCA---2626All0.000005
ORF1ab/nsp12115S115ATcaGca2525B.1.1.70.000022
ORF1ab/nsp12115S115PTcaCca1518All0.000003
ORF1ab/nsp12115S115PTcACcT218All0
ORF1ab/nsp12115S115PTcACcG118All0
ORF1ab/nsp12115S115StcAtcT1717C.370.001973
ORF1ab/nsp12115S115ATcaGca1616AE.40.695652
ORF1ab/nsp12115S115XtCatAa810All0.000002
ORF1ab/nsp12115S115XtCatGa210All0
ORF1ab/nsp12115S115StcAtcG1010B.1.1.70.000009
ORF1ab/nsp12115S115StcAtcG1010B.1.1600.000312
ORF1ab/nsp12115S115StcAtcG77AY.440.000043
ORF1ab/nsp12115S115LtCatTa46All0.000001
ORF1ab/nsp12115S115LTCACTT26All0
ORF1ab/nsp12115S115delTCA---66B.1.1.70.000005
ORF1ab/nsp12115S115StcAtcG55AY.1190.000177
ORF1ab/nsp12115S115StcAtcG55AY.4.20.000108
ORF1ab/nsp12115S115PTcaCca55B.1.1.70.000004
ORF1ab/nsp12115S115XtCatAa240.111111
ORF1ab/nsp12115S115XtCatGa240.111111
ORF1ab/nsp12115S115StcAtcG34AY.40.000005
ORF1ab/nsp12115S115StcAtcC14AY.40.000002
ORF1ab/nsp12115S115StcAtcG44B.1.177.810.000757
ORF1ab/nsp12115S115ATcaGca44B.1.6370.000292
ORF1ab/nsp12115S115TTcaAca33All0.000001
ORF1ab/nsp12115S115StcAtcG33AY.1170.000254
ORF1ab/nsp12115S115StcAtcG33AY.160.001139
ORF1ab/nsp12115S115XtCatAa33B.10.000027
ORF1ab/nsp12115S115ATcaGca33B.1.1.5190.000119
ORF1ab/nsp12115S115del1tCat-a33B.1.177.820.001432
ORF1ab/nsp12115S115del1tCat-a33B.1.3510.000089
ORF1ab/nsp12115S115StcAtcC33P.10.000047
ORF1ab/nsp12115S115ATcaGca33P.1.10.000953
ORF1ab/nsp12115S115PTcACcT220.111111
ORF1ab/nsp12115S115LTCACTT220.111111
ORF1ab/nsp12115S115ATcAGcT220.111111
ORF1ab/nsp12115S115StcAtcG22AY.1020.000053
ORF1ab/nsp12115S115delTCA---22AY.1200.000074
ORF1ab/nsp12115S115StcAtcT22AY.250.000012
ORF1ab/nsp12115S115delTCA---22AY.250.000012
ORF1ab/nsp12115S115StcAtcG22AY.30.00002
ORF1ab/nsp12115S115ATcaGca22AY.300.000791
ORF1ab/nsp12115S115delTCA---22AY.40.000003
ORF1ab/nsp12115S115delTCA---22AY.4.50.000215
ORF1ab/nsp12115S115ATcaGca22AY.440.000012
ORF1ab/nsp12115S115del1tCat-a22AY.520.001629
ORF1ab/nsp12115S115PTcaCca22B.10.000018
ORF1ab/nsp12115S115PTcaCca22B.1.10.000036
ORF1ab/nsp12115S115StcAtcT12B.1.10.000018
ORF1ab/nsp12115S115StcAtcG12B.1.10.000018
ORF1ab/nsp12115S115XtCatAa22B.1.1.70.000002
ORF1ab/nsp12115S115StcAtcG22B.1.20.000018
ORF1ab/nsp12115S115StcAtcG22B.1.4970.00063
ORF1ab/nsp12115S115StcAtcG22B.1.617.20.000008
ORF1ab/nsp12115S115ATcaGca11A0.000387
ORF1ab/nsp12115S115RTCaCGa11All0
ORF1ab/nsp12115S115ITCaATa11All0
ORF1ab/nsp12115S115FtCAtTT11All0
ORF1ab/nsp12115S115StcAtcG11AY.1010.00049
ORF1ab/nsp12115S115StcAtcG11AY.1030.000006
ORF1ab/nsp12115S115delTCA---11AY.1170.000085
ORF1ab/nsp12115S115delTCA---11AY.260.000028
ORF1ab/nsp12115S115PTcaCca11AY.260.000028
ORF1ab/nsp12115S115StcAtcG11AY.380.000499
ORF1ab/nsp12115S115ATcaGca11AY.40.000002
ORF1ab/nsp12115S115PTcaCca11AY.40.000002
ORF1ab/nsp12115S115LtCatTa11AY.430.000004
ORF1ab/nsp12115S115delTCA---11AY.46.60.000072
ORF1ab/nsp12115S115ATcaGca11AY.5.30.000337
ORF1ab/nsp12115S115PTcaCca11AY.590.00053
ORF1ab/nsp12115S115StcAtcG11AY.60.000041
ORF1ab/nsp12115S115delTCA---11AY.80.000606
ORF1ab/nsp12115S115delTCA---11AY.990.001049
ORF1ab/nsp12115S115PTcACcG11AY.990.001049
ORF1ab/nsp12115S115StcAtcG11B.10.000009
ORF1ab/nsp12115S115ATcaGca11B.1.10.000018
ORF1ab/nsp12115S115ITCaATa11B.1.10.000018
ORF1ab/nsp12115S115delTCA---11B.1.10.000018
ORF1ab/nsp12115S115delTCA---11B.1.1.10.000327
ORF1ab/nsp12115S115delTCA---11B.1.1.1390.022727
ORF1ab/nsp12115S115delTCA---11B.1.1.2360.006897
ORF1ab/nsp12115S115delTCA---11B.1.1.3480.000796
ORF1ab/nsp12115S115PTcaCca11B.1.1.4200.001006
ORF1ab/nsp12115S115StcAtcG11B.1.1.4480.002033
ORF1ab/nsp12115S115LtCatTa11B.1.1.70.000001
ORF1ab/nsp12115S115del1tCat-a11B.1.1600.000031
ORF1ab/nsp12115S115TTcaAca11B.1.1600.000031
ORF1ab/nsp12115S115XtCatAa11B.1.1770.000013
ORF1ab/nsp12115S115del1tCat-a11B.1.177.60.000977
ORF1ab/nsp12115S115StcAtcG11B.1.2470.014925
ORF1ab/nsp12115S115StcAtcG11B.1.3510.00003
ORF1ab/nsp12115S115del1tCat-a11B.1.36.10.00114
ORF1ab/nsp12115S115StcAtcG11B.1.3690.000285
ORF1ab/nsp12115S115PTcaCca11B.1.4000.000429
ORF1ab/nsp12115S115RTCaCGa11B.1.4150.014286
ORF1ab/nsp12115S115StcAtcC11B.1.4590.004082
ORF1ab/nsp12115S115ATcaGca11B.1.4620.007246
ORF1ab/nsp12115S115StcAtcG11B.1.4700.001404
ORF1ab/nsp12115S115PTcaCca11B.1.5750.000303
ORF1ab/nsp12115S115ATcaGca11B.1.617.20.000004
ORF1ab/nsp12115S115LtCatTa11B.1.617.20.000004
ORF1ab/nsp12115S115delTCA---11B.1.6300.005236
ORF1ab/nsp12115S115ATcaGca11C.350.000774
ORF1ab/nsp12115S115TTcaAca11D.20.000075
ORF1ab/nsp12115S115LtCatTa11D.20.000075
ORF1ab/nsp12115S115ATcaGca11P.10.000016
ORF1ab/nsp12115S115TTcaAca11P.10.000016
ORF1ab/nsp12115S115FtCAtTT11Q.10.000126
ORF1ab/nsp12115S115delTCA---11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.