CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp10 : Mut = T111I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp10	111	T111I	T4364I	nonsyn	aCa	aTa	5675	5675	1	13355-13357

Details of the mutation T111I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp10	111	T111I	aCa	aTa	5675	5675	All	0.001085
ORF1ab/nsp10	111	T111I	aCa	aTa	2427	2427	B.1.1.7	0.002173
ORF1ab/nsp10	111	T111I	aCa	aTa	608	608	B.1.1.523	0.95
ORF1ab/nsp10	111	T111I	aCa	aTa	355	355	AY.4.2	0.007699
ORF1ab/nsp10	111	T111I	aCa	aTa	277	277	AW.1	0.844512
ORF1ab/nsp10	111	T111I	aCa	aTa	184	184	AY.4	0.000286
ORF1ab/nsp10	111	T111I	aCa	aTa	131	131	B.1.617.2	0.000493
ORF1ab/nsp10	111	T111I	aCa	aTa	102	102	B.1.2	0.000898
ORF1ab/nsp10	111	T111I	aCa	aTa	74	74	AY.43	0.000328
ORF1ab/nsp10	111	T111I	aCa	aTa	70	70	AY.103	0.000435
ORF1ab/nsp10	111	T111I	aCa	aTa	66	66	AY.44	0.000402
ORF1ab/nsp10	111	T111I	aCa	aTa	57	57	AY.13	0.009176
ORF1ab/nsp10	111	T111I	aCa	aTa	52	52	B.1	0.000476
ORF1ab/nsp10	111	T111I	aCa	aTa	50	50	AY.75	0.002801
ORF1ab/nsp10	111	T111I	aCa	aTa	50	50	B.1.1	0.000907
ORF1ab/nsp10	111	T111I	aCa	aTa	49	49	B.1.177	0.000645
ORF1ab/nsp10	111	T111I	aCa	aTa	44	44	B.1.577	0.030241
ORF1ab/nsp10	111	T111I	aCa	aTa	36	36	B.1.1.228	0.109756
ORF1ab/nsp10	111	T111I	aCa	aTa	35	35	AY.102	0.000928
ORF1ab/nsp10	111	T111I	aCa	aTa	34	34	B.1.243	0.002366
ORF1ab/nsp10	111	T111I	aCa	aTa	32	32	B.1.177.12	0.004854
ORF1ab/nsp10	111	T111I	aCa	aTa	32	32	C.37	0.003714
ORF1ab/nsp10	111	T111I	aCa	aTa	30	30	B.1.36	0.004377
ORF1ab/nsp10	111	T111I	aCa	aTa	28	28	AY.3	0.000278
ORF1ab/nsp10	111	T111I	aCa	aTa	27	27	P.1	0.000425
ORF1ab/nsp10	111	T111I	aCa	aTa	25	25	L.3	0.088652
ORF1ab/nsp10	111	T111I	aCa	aTa	24	24	AY.42	0.000966
ORF1ab/nsp10	111	T111I	aCa	aTa	24	24	B.1.438.1	0.002574
ORF1ab/nsp10	111	T111I	aCa	aTa	22	22	B.1.351	0.000654
ORF1ab/nsp10	111	T111I	aCa	aTa	21	21	B.1.1.519	0.000834
ORF1ab/nsp10	111	T111I	aCa	aTa	20	20	AY.29	0.000315
ORF1ab/nsp10	111	T111I	aCa	aTa	19	19	AY.39	0.00047
ORF1ab/nsp10	111	T111I	aCa	aTa	19	19	AY.99.2	0.001751
ORF1ab/nsp10	111	T111I	aCa	aTa	17	17	AY.10	0.009009
ORF1ab/nsp10	111	T111I	aCa	aTa	17	17	B.1.232	0.009135
ORF1ab/nsp10	111	T111I	aCa	aTa	15	15	A.2.5.2	0.023585
ORF1ab/nsp10	111	T111I	aCa	aTa	15	15	B.1.1.521	0.080214
ORF1ab/nsp10	111	T111I	aCa	aTa	15	15	B.1.427	0.000757
ORF1ab/nsp10	111	T111I	aCa	aTa	14	14	AY.100	0.000644
ORF1ab/nsp10	111	T111I	aCa	aTa	14	14	AY.26	0.000396
ORF1ab/nsp10	111	T111I	aCa	aTa	14	14	B.1.177.75	0.014568
ORF1ab/nsp10	111	T111I	aCa	aTa	13	13	B.1.160	0.000405
ORF1ab/nsp10	111	T111I	aCa	aTa	13	13	B.1.177.53	0.0311
ORF1ab/nsp10	111	T111I	aCa	aTa	12	12	AY.25	0.000072
ORF1ab/nsp10	111	T111I	aCa	aTa	12	12	B.1.429	0.000282
ORF1ab/nsp10	111	T111I	aCa	aTa	12	12	B.1.597	0.055556
ORF1ab/nsp10	111	T111I	aCa	aTa	11	11	AY.85	0.004699
ORF1ab/nsp10	111	T111I	aCa	aTa	11	11	B.1.1.222	0.002244
ORF1ab/nsp10	111	T111I	aCa	aTa	11	11	B.1.526	0.000259
ORF1ab/nsp10	111	T111I	aCa	aTa	9	9	AY.34	0.000873
ORF1ab/nsp10	111	T111I	aCa	aTa	9	9	AY.69	0.00168
ORF1ab/nsp10	111	T111I	aCa	aTa	9	9	B.1.1.374	0.021378
ORF1ab/nsp10	111	T111I	aCa	aTa	8	8	AY.117	0.000676
ORF1ab/nsp10	111	T111I	aCa	aTa	8	8	AY.45	0.000973
ORF1ab/nsp10	111	T111I	aCa	aTa	8	8	AY.46.4	0.001316
ORF1ab/nsp10	111	T111I	aCa	aTa	8	8	B.1.221	0.000568
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	AY.119	0.000247
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	AY.36	0.001037
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	AY.5	0.000145
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	AY.9.2.1	0.013834
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	B.1.1.63	0.002701
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	B.1.177.44	0.003633
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	B.1.258	0.000466
ORF1ab/nsp10	111	T111I	aCa	aTa	7	7	B.1.575	0.002124
ORF1ab/nsp10	111	T111I	aCa	aTa	6	6	AY.39.1	0.000238
ORF1ab/nsp10	111	T111I	aCa	aTa	6	6	B.1.131	0.052632
ORF1ab/nsp10	111	T111I	aCa	aTa	6	6	B.1.215	0.057692
ORF1ab/nsp10	111	T111I	aCa	aTa	6	6	B.1.241	0.00487
ORF1ab/nsp10	111	T111I	aCa	aTa	6	6	B.1.400	0.002574
ORF1ab/nsp10	111	T111I	aCa	aTa	6	6	P.1.12	0.002904
ORF1ab/nsp10	111	T111I	aCa	aTa	5	5	AY.118	0.000313
ORF1ab/nsp10	111	T111I	aCa	aTa	5	5	AY.78	0.007704
ORF1ab/nsp10	111	T111I	aCa	aTa	5	5	AY.9.1	0.000419
ORF1ab/nsp10	111	T111I	aCa	aTa	5	5	P.1.13	0.004492
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	A	0.001548
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.121	0.000541
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.23	0.000279
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.47	0.000124
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.54	0.000381
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.6	0.000165
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.61	0.000419
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	AY.70	0.000834
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	B	0.000511
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	B.1.1.243	0.016327
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	B.1.258.17	0.000416
ORF1ab/nsp10	111	T111I	aCa	aTa	4	4	B.1.36.8	0.004
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.116	0.00086
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.120	0.000112
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.14	0.000264
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.20	0.000117
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.37	0.000948
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.51	0.002727
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.62	0.001307
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.8	0.001818
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.9.2	0.00011
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.91	0.002191
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	AY.98	0.000237
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.1.28	0.000934
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.1.70	0.001023
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.177.86	0.00055
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.311	0.000824
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.456	0.009804
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.517	0.001281
ORF1ab/nsp10	111	T111I	aCa	aTa	3	3	B.1.617.1	0.000387
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.111	0.000366
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.113	0.000285
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.27	0.000129
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.3.1	0.000171
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.31	0.037037
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.32	0.001065
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.33	0.000134
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.4.5	0.000215
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.5.4	0.000553
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.65	0.001066
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	AY.74	0.000231
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.1	0.000653
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.174	0.006757
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.214	0.000111
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.241	0.004141
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.306	0.000877
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.311	0.000716
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.317	0.000823
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.328	0.033898
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.368	0.006173
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.371	0.020833
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.1.448	0.004065
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.177.62	0.002384
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.177.79	0.004684
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.240	0.000431
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.369	0.00057
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.395	0.014085
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.405	0.024691
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.509	0.001732
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.523	0.004902
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.595	0.000522
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.596	0.000174
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	B.1.621	0.000177
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	C.1.2	0.008511
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	C.36	0.001821
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	P.1.14	0.000096
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	P.1.15	0.000465
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	P.2	0.000373
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	P.3	0.00319
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	Q.8	0.00033
ORF1ab/nsp10	111	T111I	aCa	aTa	2	2	R.1	0.00018
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	A.1	0.000282
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	A.2.5	0.000499
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	A.2.5.1	0.004808
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	A.28	0.002646
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AL.1	0.012987
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.104	0.001984
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.116.1	0.000311
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.16	0.00038
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.16.1	0.00047
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.19	0.00114
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.30	0.000396
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.38	0.000499
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.4.4	0.000409
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.40	0.000964
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.57	0.000656
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.7	0.000196
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.71	0.000475
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.72	0.001361
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.75.1	0.00018
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.84	0.000437
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.92	0.000287
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.93	0.000273
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.94	0.000443
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AY.98.1	0.000048
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	AZ.3	0.00152
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.136	0.021277
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.141	0.002012
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.161	0.003534
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.176	0.000439
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.220	0.001859
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.231	0.003096
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.237	0.005405
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.254	0.011236
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.291	0.000742
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.316	0.000925
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.318	0.000302
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.33	0.000421
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.354	0.004386
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.369	0.000446
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.375	0.011905
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.464	0.001473
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.50	0.000679
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.1.51	0.001718
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.160.30	0.002976
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.17	0.000821
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.20	0.001517
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.21	0.000076
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.4	0.000211
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.55	0.002331
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.60	0.000218
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.73	0.000566
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.177.83	0.001481
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.219	0.009434
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.221.3	0.000833
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.258.2	0.004505
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.258.3	0.001675
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.340	0.004292
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.349	0.000715
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.36.18	0.00042
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.36.29	0.000517
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.379	0.017241
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.398	0.002976
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.416.1	0.001563
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.420	0.010417
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.438	0.006536
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.453	0.003236
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.469	0.00361
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.470	0.001404
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.525	0.000113
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.6	0.017241
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.619.1	0.000641
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.637	0.000073
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.1.8	0.001972
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	B.52	0.010101
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	C.17	0.055556
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	C.18	0.002591
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	D.2	0.000075
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	N.4	0.004255
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	P.1.7	0.000319
ORF1ab/nsp10	111	T111I	aCa	aTa	1	1	Y.1	0.012821

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.