CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp10 : CodonNum = 8

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp108P8SP4261SnonsynCctTct11151115113046-13048
ORF1ab/nsp108P8PP4261PsynccTccC7945330.67128513046-13048
ORF1ab/nsp108P8PP4261PsynccTccA7942150.27078113046-13048
ORF1ab/nsp108P8PP4261PsynccTccG794460.057934513046-13048
ORF1ab/nsp108P8LP4261LnonsyncCtcTt3223040.94409913046-13048
ORF1ab/nsp108P8LP4261LnonsyncCTcTC322170.05279513046-13048
ORF1ab/nsp108P8LP4261LnonsyncCTcTA32210.0031055913046-13048
ORF1ab/nsp108P8HP4261HnonsyncCtcAt7878113046-13048
ORF1ab/nsp108P8TP4261TnonsynCctAct31300.96774213046-13048
ORF1ab/nsp108P8TP4261TnonsynCcTAcG3110.032258113046-13048
ORF1ab/nsp108P8delP4261deldelCCT---2424113046-13048
ORF1ab/nsp108P8AP4261AnonsynCctGct22113046-13048
ORF1ab/nsp108P8del1P4261del1delccTcc-210.513046-13048
ORF1ab/nsp108P8del1P4261del1delCct-ct210.513046-13048
ORF1ab/nsp108P8FP4261FnonsynCCTTTC11113046-13048
ORF1ab/nsp108P8del2P4261del2delCCt--t11113046-13048

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp108P8SCctTct11151115All0.000213
ORF1ab/nsp108P8PccTccC533794All0.000102
ORF1ab/nsp108P8PccTccA215794All0.000041
ORF1ab/nsp108P8PccTccG46794All0.000009
ORF1ab/nsp108P8SCctTct660660AY.260.018685
ORF1ab/nsp108P8PccTccC364369AY.1040.722222
ORF1ab/nsp108P8PccTccG3369AY.1040.005952
ORF1ab/nsp108P8PccTccA2369AY.1040.003968
ORF1ab/nsp108P8LcCtcTt304322All0.000058
ORF1ab/nsp108P8LcCTcTC17322All0.000003
ORF1ab/nsp108P8LcCTcTA1322All0
ORF1ab/nsp108P8PccTccA108110AY.250.00065
ORF1ab/nsp108P8PccTccC2110AY.250.000012
ORF1ab/nsp108P8SCctTct8181AY.430.000359
ORF1ab/nsp108P8HcCtcAt7878All0.000015
ORF1ab/nsp108P8PccTccA5170AY.40.000079
ORF1ab/nsp108P8PccTccC1770AY.40.000026
ORF1ab/nsp108P8PccTccG270AY.40.000003
ORF1ab/nsp108P8LcCtcTt5469B.1.617.20.000203
ORF1ab/nsp108P8LcCTcTC1569B.1.617.20.000056
ORF1ab/nsp108P8PccTccC3462B.1.1.70.00003
ORF1ab/nsp108P8PccTccG1562B.1.1.70.000013
ORF1ab/nsp108P8PccTccA1362B.1.1.70.000012
ORF1ab/nsp108P8HcCtcAt4242B.1.5170.017933
ORF1ab/nsp108P8SCctTct4141AY.250.000247
ORF1ab/nsp108P8SCctTct3939B.1.617.20.000147
ORF1ab/nsp108P8SCctTct3838B.1.1.70.000034
ORF1ab/nsp108P8PccTccC3237B.1.617.20.00012
ORF1ab/nsp108P8PccTccA337B.1.617.20.000011
ORF1ab/nsp108P8PccTccG237B.1.617.20.000008
ORF1ab/nsp108P8SCctTct3434AY.1210.004601
ORF1ab/nsp108P8LcCtcTt3434AY.40.000053
ORF1ab/nsp108P8PccTccC3232AY.1030.000199
ORF1ab/nsp108P8TCctAct3031All0.000006
ORF1ab/nsp108P8TCcTAcG131All0
ORF1ab/nsp108P8SCctTct3131AY.40.000048
ORF1ab/nsp108P8LcCtcTt3030AY.1000.00138
ORF1ab/nsp108P8SCctTct2727B.1.20.000238
ORF1ab/nsp108P8delCCT---2424All0.000005
ORF1ab/nsp108P8SCctTct2222B.1.2430.001531
ORF1ab/nsp108P8LcCtcTt1717B.1.1.2140.000943
ORF1ab/nsp108P8LcCtcTt1616AY.250.000096
ORF1ab/nsp108P8LcCtcTt1212AY.1030.000075
ORF1ab/nsp108P8SCctTct1010AY.30.000099
ORF1ab/nsp108P8LcCtcTt1010B.10.000092
ORF1ab/nsp108P8PccTccA1010B.1.1.4160.00905
ORF1ab/nsp108P8LcCtcTt1010B.1.20.000088
ORF1ab/nsp108P8LcCtcTt99AY.30.00009
ORF1ab/nsp108P8LcCtcTt99B.1.10.000163
ORF1ab/nsp108P8SCctTct88AY.1170.000676
ORF1ab/nsp108P8SCctTct88AY.4.20.000174
ORF1ab/nsp108P8SCctTct88B.10.000073
ORF1ab/nsp108P8PccTccG78B.1.1600.000218
ORF1ab/nsp108P8PccTccC18B.1.1600.000031
ORF1ab/nsp108P8PccTccA57AY.430.000022
ORF1ab/nsp108P8PccTccC27AY.430.000009
ORF1ab/nsp108P8LcCtcTt67AY.440.000037
ORF1ab/nsp108P8LcCTcTC17AY.440.000006
ORF1ab/nsp108P8LcCtcTt77AY.50.000145
ORF1ab/nsp108P8SCctTct66AY.1030.000037
ORF1ab/nsp108P8SCctTct66AY.200.000233
ORF1ab/nsp108P8LcCtcTt66AY.430.000027
ORF1ab/nsp108P8SCctTct66AY.440.000037
ORF1ab/nsp108P8PccTccA46AY.440.000024
ORF1ab/nsp108P8PccTccC26AY.440.000012
ORF1ab/nsp108P8LcCtcTt66B.1.1.70.000005
ORF1ab/nsp108P8HcCtcAt66B.1.4290.000141
ORF1ab/nsp108P8SCctTct66B.6.80.049587
ORF1ab/nsp108P8SCctTct55AY.1180.000313
ORF1ab/nsp108P8SCctTct55AY.360.000741
ORF1ab/nsp108P8HcCtcAt55AY.430.000022
ORF1ab/nsp108P8PccTccG55AY.880.004421
ORF1ab/nsp108P8SCctTct55AY.9.20.000184
ORF1ab/nsp108P8PccTccC55B.1.1.3970.011261
ORF1ab/nsp108P8delCCT---55B.1.1.70.000004
ORF1ab/nsp108P8SCctTct55B.1.4590.020408
ORF1ab/nsp108P8LcCtcTt55B.1.5490.035971
ORF1ab/nsp108P8LcCtcTt44AY.1210.000541
ORF1ab/nsp108P8PccTccG34AY.260.000085
ORF1ab/nsp108P8PccTccA14AY.260.000028
ORF1ab/nsp108P8LcCtcTt44AY.360.000593
ORF1ab/nsp108P8PccTccC44AY.390.000099
ORF1ab/nsp108P8PccTccC44B.10.000037
ORF1ab/nsp108P8PccTccC24B.1.10.000036
ORF1ab/nsp108P8PccTccA24B.1.10.000036
ORF1ab/nsp108P8SCctTct44B.1.1770.000053
ORF1ab/nsp108P8LcCtcTt44B.1.2320.002149
ORF1ab/nsp108P8TCctAct34B.1.617.20.000011
ORF1ab/nsp108P8TCcTAcG14B.1.617.20.000004
ORF1ab/nsp108P8TCctAct44P.10.000063
ORF1ab/nsp108P8LcCtcTt33AY.1180.000188
ORF1ab/nsp108P8SCctTct33AY.1190.000106
ORF1ab/nsp108P8PccTccC23AY.1190.000071
ORF1ab/nsp108P8PccTccA13AY.1190.000035
ORF1ab/nsp108P8PccTccC33AY.120.20.003856
ORF1ab/nsp108P8TCctAct33AY.40.000005
ORF1ab/nsp108P8SCctTct33AY.4.40.001227
ORF1ab/nsp108P8delCCT---33AY.4.50.000322
ORF1ab/nsp108P8TCctAct33AY.50.000062
ORF1ab/nsp108P8LcCtcTt33AY.690.00056
ORF1ab/nsp108P8LcCtcTt33AY.920.000862
ORF1ab/nsp108P8HcCtcAt33B.10.000027
ORF1ab/nsp108P8SCctTct33B.1.10.000054
ORF1ab/nsp108P8PccTccA33B.1.1.5190.000119
ORF1ab/nsp108P8LcCtcTt33B.1.1600.000094
ORF1ab/nsp108P8HcCtcAt33B.1.617.20.000011
ORF1ab/nsp108P8PccTccC33C.370.000348
ORF1ab/nsp108P8SCctTct22AD.20.000438
ORF1ab/nsp108P8ACctGct22All0
ORF1ab/nsp108P8del1ccTcc-12All0
ORF1ab/nsp108P8del1Cct-ct12All0
ORF1ab/nsp108P8LcCtcTt22AY.1130.000285
ORF1ab/nsp108P8PccTccC22AY.1130.000285
ORF1ab/nsp108P8HcCtcAt22AY.250.000012
ORF1ab/nsp108P8LcCtcTt22AY.260.000057
ORF1ab/nsp108P8SCctTct22AY.270.000129
ORF1ab/nsp108P8PccTccG22AY.290.000032
ORF1ab/nsp108P8PccTccC22AY.300.000791
ORF1ab/nsp108P8SCctTct22AY.320.001065
ORF1ab/nsp108P8LcCtcTt22AY.340.000194
ORF1ab/nsp108P8TCctAct22AY.430.000009
ORF1ab/nsp108P8TCctAct22AY.440.000012
ORF1ab/nsp108P8LcCtcTt22AY.46.60.000144
ORF1ab/nsp108P8TCctAct22AY.610.00021
ORF1ab/nsp108P8SCctTct22AY.610.00021
ORF1ab/nsp108P8SCctTct22AY.690.000373
ORF1ab/nsp108P8SCctTct22AY.920.000575
ORF1ab/nsp108P8TCctAct22B.10.000018
ORF1ab/nsp108P8SCctTct22B.1.177.510.009132
ORF1ab/nsp108P8TCctAct22B.1.20.000018
ORF1ab/nsp108P8HcCtcAt22B.1.20.000018
ORF1ab/nsp108P8PccTccA22B.1.20.000018
ORF1ab/nsp108P8HcCtcAt22B.1.221.10.005814
ORF1ab/nsp108P8LcCtcTt22B.1.2430.000139
ORF1ab/nsp108P8PccTccC12B.1.2430.00007
ORF1ab/nsp108P8PccTccG12B.1.2430.00007
ORF1ab/nsp108P8PccTccC22B.1.2580.000133
ORF1ab/nsp108P8SCctTct22B.1.4290.000047
ORF1ab/nsp108P8TCctAct22B.1.4290.000047
ORF1ab/nsp108P8SCctTct22B.1.5260.000047
ORF1ab/nsp108P8SCctTct22B.1.5960.000174
ORF1ab/nsp108P8SCctTct22C.370.000232
ORF1ab/nsp108P8LcCtcTt22D.20.00015
ORF1ab/nsp108P8SCctTct22P.50.027397
ORF1ab/nsp108P8PccTccC22Q.10.000253
ORF1ab/nsp108P8HcCtcAt11A0.000387
ORF1ab/nsp108P8SCctTct11A.20.000662
ORF1ab/nsp108P8LcCtcTt11A.2.20.001689
ORF1ab/nsp108P8LcCtcTt11A.2.50.000499
ORF1ab/nsp108P8LcCtcTt11A.210.00277
ORF1ab/nsp108P8LcCtcTt11A.220.066667
ORF1ab/nsp108P8FCCTTTC11All0
ORF1ab/nsp108P8del2CCt--t11All0
ORF1ab/nsp108P8SCctTct11AY.1000.000046
ORF1ab/nsp108P8SCctTct11AY.1020.000027
ORF1ab/nsp108P8LcCtcTt11AY.1020.000027
ORF1ab/nsp108P8HcCtcAt11AY.1020.000027
ORF1ab/nsp108P8SCctTct11AY.1130.000142
ORF1ab/nsp108P8PccTccC11AY.1170.000085
ORF1ab/nsp108P8LcCtcTt11AY.120.000316
ORF1ab/nsp108P8HcCtcAt11AY.1200.000037
ORF1ab/nsp108P8SCctTct11AY.1200.000037
ORF1ab/nsp108P8PccTccG11AY.1200.000037
ORF1ab/nsp108P8LcCtcTt11AY.140.000088
ORF1ab/nsp108P8HcCtcAt11AY.160.00038
ORF1ab/nsp108P8delCCT---11AY.190.00114
ORF1ab/nsp108P8LcCtcTt11AY.200.000039
ORF1ab/nsp108P8LcCtcTt11AY.230.00007
ORF1ab/nsp108P8PccTccG11AY.30.00001
ORF1ab/nsp108P8LcCtcTt11AY.3.10.000085
ORF1ab/nsp108P8SCctTct11AY.300.000396
ORF1ab/nsp108P8LcCtcTt11AY.330.000067
ORF1ab/nsp108P8LcCtcTt11AY.390.000025
ORF1ab/nsp108P8SCctTct11AY.390.000025
ORF1ab/nsp108P8PccTccA11AY.39.10.00004
ORF1ab/nsp108P8HcCtcAt11AY.40.000002
ORF1ab/nsp108P8PccTccA11AY.4.50.000107
ORF1ab/nsp108P8SCctTct11AY.410.000294
ORF1ab/nsp108P8PccTccC11AY.420.00004
ORF1ab/nsp108P8LcCtcTt11AY.420.00004
ORF1ab/nsp108P8delCCT---11AY.430.000004
ORF1ab/nsp108P8LcCtcTt11AY.460.000104
ORF1ab/nsp108P8del2CCt--t11AY.46.20.000635
ORF1ab/nsp108P8LcCtcTt11AY.470.000031
ORF1ab/nsp108P8PccTccC11AY.50.000021
ORF1ab/nsp108P8PccTccC11AY.5.30.000337
ORF1ab/nsp108P8SCctTct11AY.5.40.000277
ORF1ab/nsp108P8delCCT---11AY.60.000041
ORF1ab/nsp108P8LcCtcTt11AY.60.000041
ORF1ab/nsp108P8LcCtcTt11AY.610.000105
ORF1ab/nsp108P8SCctTct11AY.620.000436
ORF1ab/nsp108P8LcCtcTt11AY.640.000595
ORF1ab/nsp108P8PccTccA11AY.670.000464
ORF1ab/nsp108P8delCCT---11AY.720.001361
ORF1ab/nsp108P8LcCtcTt11AY.750.000056
ORF1ab/nsp108P8LcCtcTt11AY.75.10.00018
ORF1ab/nsp108P8PccTccC11AY.820.001357
ORF1ab/nsp108P8PccTccC11AY.840.000437
ORF1ab/nsp108P8LcCTcTC11AY.900.000684
ORF1ab/nsp108P8PccTccC11AY.900.000684
ORF1ab/nsp108P8PccTccC11AY.920.000287
ORF1ab/nsp108P8TCctAct11AY.930.000273
ORF1ab/nsp108P8SCctTct11AY.980.000079
ORF1ab/nsp108P8PccTccA11AY.980.000079
ORF1ab/nsp108P8PccTccC11B0.000128
ORF1ab/nsp108P8HcCtcAt11B0.000128
ORF1ab/nsp108P8del1ccTcc-11B.1.10.000018
ORF1ab/nsp108P8delCCT---11B.1.1.10.000327
ORF1ab/nsp108P8SCctTct11B.1.1.2090.008929
ORF1ab/nsp108P8SCctTct11B.1.1.2140.000055
ORF1ab/nsp108P8SCctTct11B.1.1.280.000311
ORF1ab/nsp108P8PccTccC11B.1.1.2910.000742
ORF1ab/nsp108P8LcCtcTt11B.1.1.2940.001266
ORF1ab/nsp108P8delCCT---11B.1.1.3480.000796
ORF1ab/nsp108P8delCCT---11B.1.1.370.000193
ORF1ab/nsp108P8LcCtcTt11B.1.1.4640.001473
ORF1ab/nsp108P8ACctGct11B.1.1.70.000001
ORF1ab/nsp108P8TCctAct11B.1.1.70.000001
ORF1ab/nsp108P8LcCtcTt11B.1.1.710.006061
ORF1ab/nsp108P8PccTccC11B.1.1470.000756
ORF1ab/nsp108P8SCctTct11B.1.1600.000031
ORF1ab/nsp108P8LcCtcTt11B.1.160.310.008065
ORF1ab/nsp108P8LcCtcTt11B.1.160.320.004292
ORF1ab/nsp108P8PccTccG11B.1.160.90.007194
ORF1ab/nsp108P8delCCT---11B.1.1770.000013
ORF1ab/nsp108P8PccTccA11B.1.1770.000013
ORF1ab/nsp108P8LcCtcTt11B.1.177.180.00116
ORF1ab/nsp108P8LcCtcTt11B.1.177.200.001517
ORF1ab/nsp108P8SCctTct11B.1.177.450.000381
ORF1ab/nsp108P8LcCtcTt11B.1.177.540.000606
ORF1ab/nsp108P8LcCtcTt11B.1.177.570.000281
ORF1ab/nsp108P8HcCtcAt11B.1.177.60.000977
ORF1ab/nsp108P8PccTccG11B.1.177.600.000218
ORF1ab/nsp108P8PccTccC11B.1.177.690.001484
ORF1ab/nsp108P8delCCT---11B.1.177.830.001481
ORF1ab/nsp108P8SCctTct11B.1.2060.000816
ORF1ab/nsp108P8LcCtcTt11B.1.221.10.002907
ORF1ab/nsp108P8LcCtcTt11B.1.2400.000216
ORF1ab/nsp108P8HcCtcAt11B.1.2430.00007
ORF1ab/nsp108P8TCctAct11B.1.2430.00007
ORF1ab/nsp108P8HcCtcAt11B.1.2580.000067
ORF1ab/nsp108P8TCctAct11B.1.258.30.001675
ORF1ab/nsp108P8HcCtcAt11B.1.3010.005917
ORF1ab/nsp108P8delCCT---11B.1.3110.000275
ORF1ab/nsp108P8PccTccA11B.1.3500.002933
ORF1ab/nsp108P8PccTccA11B.1.3510.00003
ORF1ab/nsp108P8SCctTct11B.1.3510.00003
ORF1ab/nsp108P8HcCtcAt11B.1.360.000146
ORF1ab/nsp108P8PccTccA11B.1.36.120.009615
ORF1ab/nsp108P8LcCtcTt11B.1.36.160.001425
ORF1ab/nsp108P8SCctTct11B.1.36.180.00042
ORF1ab/nsp108P8LcCTcTA11B.1.3710.001122
ORF1ab/nsp108P8delCCT---11B.1.4150.014286
ORF1ab/nsp108P8LcCtcTt11B.1.4270.00005
ORF1ab/nsp108P8TCctAct11B.1.4270.00005
ORF1ab/nsp108P8LcCtcTt11B.1.4290.000024
ORF1ab/nsp108P8SCctTct11B.1.4700.001404
ORF1ab/nsp108P8PccTccA11B.1.4990.00105
ORF1ab/nsp108P8LcCtcTt11B.1.5250.000113
ORF1ab/nsp108P8LcCtcTt11B.1.5260.000024
ORF1ab/nsp108P8ACctGct11B.1.5820.000491
ORF1ab/nsp108P8PccTccC11B.1.5950.000261
ORF1ab/nsp108P8PccTccC11B.1.5960.000087
ORF1ab/nsp108P8SCctTct11B.1.6090.000479
ORF1ab/nsp108P8delCCT---11B.1.617.10.000129
ORF1ab/nsp108P8delCCT---11B.1.617.20.000004
ORF1ab/nsp108P8FCCTTTC11B.1.617.20.000004
ORF1ab/nsp108P8del1Cct-ct11B.1.617.20.000004
ORF1ab/nsp108P8HcCtcAt11B.1.6230.000536
ORF1ab/nsp108P8delCCT---11B.1.6300.005236
ORF1ab/nsp108P8SCctTct11B.1.6370.000073
ORF1ab/nsp108P8HcCtcAt11B.1.88.10.004808
ORF1ab/nsp108P8delCCT---11C.170.055556
ORF1ab/nsp108P8SCctTct11C.330.058824
ORF1ab/nsp108P8delCCT---11N.40.004255
ORF1ab/nsp108P8LcCtcTt11P.10.000016
ORF1ab/nsp108P8PccTccG11P.10.000016
ORF1ab/nsp108P8SCctTct11P.1.130.000898
ORF1ab/nsp108P8PccTccC11P.1.140.000048
ORF1ab/nsp108P8SCctTct11P.70.004367
ORF1ab/nsp108P8SCctTct11Q.30.000145
ORF1ab/nsp108P8PccTccG11Q.80.000165
ORF1ab/nsp108P8SCctTct11R.10.00009
ORF1ab/nsp108P8PccTccA11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.