CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp10 : CodonNum = 64

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1064D64DD4317DsyngaTgaC1446814468113214-13216
ORF1ab/nsp1064D64ED4317EnonsyngaTgaG3803680.96842113214-13216
ORF1ab/nsp1064D64ED4317EnonsyngaTgaA380120.031578913214-13216
ORF1ab/nsp1064D64YD4317YnonsynGatTat1616113214-13216
ORF1ab/nsp1064D64GD4317GnonsyngAtgGt1414113214-13216
ORF1ab/nsp1064D64delD4317deldelGAT---1212113214-13216
ORF1ab/nsp1064D64ND4317NnonsynGatAat1010113214-13216
ORF1ab/nsp1064D64VD4317VnonsyngAtgTt22113214-13216
ORF1ab/nsp1064D64HD4317HnonsynGatCat22113214-13216

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1064D64DgaTgaC1446814468All0.002767
ORF1ab/nsp1064D64DgaTgaC1072710727AY.99.20.988572
ORF1ab/nsp1064D64DgaTgaC14171417B.1.20.012477
ORF1ab/nsp1064D64DgaTgaC617617AY.99.10.958075
ORF1ab/nsp1064D64DgaTgaC500500AY.990.524659
ORF1ab/nsp1064D64EgaTgaG368380All0.00007
ORF1ab/nsp1064D64EgaTgaA12380All0.000002
ORF1ab/nsp1064D64DgaTgaC346346B.1.5260.008133
ORF1ab/nsp1064D64EgaTgaG339339B.1.1.3720.233471
ORF1ab/nsp1064D64DgaTgaC300300B.1.1.70.000269
ORF1ab/nsp1064D64DgaTgaC6363AY.250.000379
ORF1ab/nsp1064D64DgaTgaC4747B.1.617.20.000177
ORF1ab/nsp1064D64DgaTgaC3232AY.40.00005
ORF1ab/nsp1064D64DgaTgaC2828AY.440.00017
ORF1ab/nsp1064D64DgaTgaC2727B.10.000247
ORF1ab/nsp1064D64DgaTgaC2323AY.540.002193
ORF1ab/nsp1064D64DgaTgaC1919AY.1030.000118
ORF1ab/nsp1064D64DgaTgaC1717AY.430.000075
ORF1ab/nsp1064D64YGatTat1616All0.000003
ORF1ab/nsp1064D64DgaTgaC1515P.10.000236
ORF1ab/nsp1064D64GgAtgGt1414All0.000003
ORF1ab/nsp1064D64DgaTgaC1414B.1.3710.015713
ORF1ab/nsp1064D64DgaTgaC1313AY.30.000129
ORF1ab/nsp1064D64DgaTgaC1313AY.5.30.004386
ORF1ab/nsp1064D64delGAT---1212All0.000002
ORF1ab/nsp1064D64DgaTgaC1111AY.1090.008136
ORF1ab/nsp1064D64DgaTgaC1111B.1.177.770.007988
ORF1ab/nsp1064D64DgaTgaC1111B.1.3510.000327
ORF1ab/nsp1064D64NGatAat1010All0.000002
ORF1ab/nsp1064D64DgaTgaC1010B.1.1.3740.023753
ORF1ab/nsp1064D64DgaTgaC99AY.50.000186
ORF1ab/nsp1064D64EgaTgaG89B.1.1.70.000007
ORF1ab/nsp1064D64EgaTgaA19B.1.1.70.000001
ORF1ab/nsp1064D64DgaTgaC88AY.1190.000282
ORF1ab/nsp1064D64DgaTgaC88AY.230.000558
ORF1ab/nsp1064D64DgaTgaC88B.1.10.000145
ORF1ab/nsp1064D64DgaTgaC77AY.1180.000439
ORF1ab/nsp1064D64DgaTgaC77B.1.5960.00061
ORF1ab/nsp1064D64DgaTgaC66AY.360.000889
ORF1ab/nsp1064D64DgaTgaC55AY.460.00052
ORF1ab/nsp1064D64DgaTgaC55AY.750.00028
ORF1ab/nsp1064D64YGatTat55B.10.000046
ORF1ab/nsp1064D64EgaTgaG55B.1.10.000091
ORF1ab/nsp1064D64GgAtgGt55B.1.1.70.000004
ORF1ab/nsp1064D64DgaTgaC55B.1.4270.000252
ORF1ab/nsp1064D64YGatTat440.222222
ORF1ab/nsp1064D64EgaTgaA44AY.250.000024
ORF1ab/nsp1064D64DgaTgaC44AY.330.000267
ORF1ab/nsp1064D64DgaTgaC44AY.46.20.002541
ORF1ab/nsp1064D64DgaTgaC44AY.470.000124
ORF1ab/nsp1064D64DgaTgaC44AY.840.00175
ORF1ab/nsp1064D64DgaTgaC44B.1.1600.000125
ORF1ab/nsp1064D64DgaTgaC44B.1.2370.0199
ORF1ab/nsp1064D64DgaTgaC44Q.30.00058
ORF1ab/nsp1064D64EgaTgaA330.166667
ORF1ab/nsp1064D64DgaTgaC33AY.1130.000427
ORF1ab/nsp1064D64DgaTgaC33AY.1170.000254
ORF1ab/nsp1064D64DgaTgaC33AY.390.000074
ORF1ab/nsp1064D64DgaTgaC33B0.000383
ORF1ab/nsp1064D64GgAtgGt33B.10.000027
ORF1ab/nsp1064D64DgaTgaC33B.1.1.4090.008499
ORF1ab/nsp1064D64DgaTgaC33B.1.1.5190.000119
ORF1ab/nsp1064D64delGAT---33B.1.1.70.000003
ORF1ab/nsp1064D64DgaTgaC33B.1.1770.00004
ORF1ab/nsp1064D64DgaTgaC33B.1.177.170.002463
ORF1ab/nsp1064D64DgaTgaC33B.1.4290.000071
ORF1ab/nsp1064D64HGatCat220.111111
ORF1ab/nsp1064D64HGatCat22All0
ORF1ab/nsp1064D64VgAtgTt22All0
ORF1ab/nsp1064D64EgaTgaA12AY.1030.000006
ORF1ab/nsp1064D64EgaTgaG12AY.1030.000006
ORF1ab/nsp1064D64DgaTgaC22AY.1140.000462
ORF1ab/nsp1064D64DgaTgaC22AY.130.000322
ORF1ab/nsp1064D64NGatAat22AY.250.000012
ORF1ab/nsp1064D64DgaTgaC22AY.300.000791
ORF1ab/nsp1064D64DgaTgaC22AY.46.50.000397
ORF1ab/nsp1064D64EgaTgaG22AY.470.000062
ORF1ab/nsp1064D64DgaTgaC22AY.500.001599
ORF1ab/nsp1064D64DgaTgaC22AY.590.001059
ORF1ab/nsp1064D64DgaTgaC22AY.600.001876
ORF1ab/nsp1064D64DgaTgaC22AY.610.00021
ORF1ab/nsp1064D64EgaTgaG22AY.900.001369
ORF1ab/nsp1064D64GgAtgGt22AY.98.10.000097
ORF1ab/nsp1064D64DgaTgaC22B.1.1.2030.033898
ORF1ab/nsp1064D64DgaTgaC22B.1.1.4480.004065
ORF1ab/nsp1064D64DgaTgaC22B.1.1.5260.007092
ORF1ab/nsp1064D64NGatAat22B.1.1.70.000002
ORF1ab/nsp1064D64EgaTgaG22B.1.20.000018
ORF1ab/nsp1064D64DgaTgaC22B.1.2430.000139
ORF1ab/nsp1064D64DgaTgaC22B.1.466.20.000782
ORF1ab/nsp1064D64DgaTgaC22B.1.5950.000522
ORF1ab/nsp1064D64DgaTgaC22B.1.617.10.000258
ORF1ab/nsp1064D64DgaTgaC22C.370.000232
ORF1ab/nsp1064D64DgaTgaC22D.20.00015
ORF1ab/nsp1064D64DgaTgaC22P.1.10.000635
ORF1ab/nsp1064D64DgaTgaC22P.1.140.000096
ORF1ab/nsp1064D64DgaTgaC11A0.000387
ORF1ab/nsp1064D64DgaTgaC11AY.1000.000046
ORF1ab/nsp1064D64DgaTgaC11AY.1020.000027
ORF1ab/nsp1064D64DgaTgaC11AY.1050.000643
ORF1ab/nsp1064D64DgaTgaC11AY.1110.000183
ORF1ab/nsp1064D64DgaTgaC11AY.1160.000287
ORF1ab/nsp1064D64EgaTgaA11AY.200.000039
ORF1ab/nsp1064D64NGatAat11AY.200.000039
ORF1ab/nsp1064D64delGAT---11AY.250.000006
ORF1ab/nsp1064D64DgaTgaC11AY.290.000016
ORF1ab/nsp1064D64DgaTgaC11AY.340.000097
ORF1ab/nsp1064D64DgaTgaC11AY.350.000233
ORF1ab/nsp1064D64DgaTgaC11AY.39.10.00004
ORF1ab/nsp1064D64NGatAat11AY.40.000002
ORF1ab/nsp1064D64EgaTgaG11AY.4.20.000022
ORF1ab/nsp1064D64DgaTgaC11AY.410.000294
ORF1ab/nsp1064D64NGatAat11AY.430.000004
ORF1ab/nsp1064D64VgAtgTt11AY.440.000006
ORF1ab/nsp1064D64DgaTgaC11AY.46.10.001027
ORF1ab/nsp1064D64DgaTgaC11AY.46.30.000934
ORF1ab/nsp1064D64NGatAat11AY.46.60.000072
ORF1ab/nsp1064D64DgaTgaC11AY.520.000814
ORF1ab/nsp1064D64delGAT---11AY.600.000938
ORF1ab/nsp1064D64GgAtgGt11AY.610.000105
ORF1ab/nsp1064D64DgaTgaC11AY.620.000436
ORF1ab/nsp1064D64DgaTgaC11AY.640.000595
ORF1ab/nsp1064D64EgaTgaG11AY.70.000196
ORF1ab/nsp1064D64NGatAat11AY.740.000116
ORF1ab/nsp1064D64DgaTgaC11AY.920.000287
ORF1ab/nsp1064D64EgaTgaG11B0.000128
ORF1ab/nsp1064D64EgaTgaA11B.10.000009
ORF1ab/nsp1064D64VgAtgTt11B.10.000009
ORF1ab/nsp1064D64delGAT---11B.10.000009
ORF1ab/nsp1064D64DgaTgaC11B.1.1.10.000327
ORF1ab/nsp1064D64delGAT---11B.1.1.10.000327
ORF1ab/nsp1064D64DgaTgaC11B.1.1.2140.000055
ORF1ab/nsp1064D64DgaTgaC11B.1.1.2160.00089
ORF1ab/nsp1064D64DgaTgaC11B.1.1.3110.000358
ORF1ab/nsp1064D64DgaTgaC11B.1.1.3180.000302
ORF1ab/nsp1064D64delGAT---11B.1.1.3480.000796
ORF1ab/nsp1064D64DgaTgaC11B.1.1.3980.003226
ORF1ab/nsp1064D64EgaTgaA11B.1.1.3980.003226
ORF1ab/nsp1064D64DgaTgaC11B.1.1.4200.001006
ORF1ab/nsp1064D64YGatTat11B.1.1.70.000001
ORF1ab/nsp1064D64YGatTat11B.1.1600.000031
ORF1ab/nsp1064D64EgaTgaG11B.1.1770.000013
ORF1ab/nsp1064D64delGAT---11B.1.1770.000013
ORF1ab/nsp1064D64DgaTgaC11B.1.177.750.001041
ORF1ab/nsp1064D64delGAT---11B.1.177.830.001481
ORF1ab/nsp1064D64YGatTat11B.1.177.830.001481
ORF1ab/nsp1064D64DgaTgaC11B.1.177.870.000728
ORF1ab/nsp1064D64YGatTat11B.1.20.000009
ORF1ab/nsp1064D64DgaTgaC11B.1.2100.002132
ORF1ab/nsp1064D64DgaTgaC11B.1.214.20.0006
ORF1ab/nsp1064D64DgaTgaC11B.1.214.30.007143
ORF1ab/nsp1064D64YGatTat11B.1.2340.000132
ORF1ab/nsp1064D64DgaTgaC11B.1.2580.000067
ORF1ab/nsp1064D64DgaTgaC11B.1.3330.010526
ORF1ab/nsp1064D64DgaTgaC11B.1.36.260.002857
ORF1ab/nsp1064D64DgaTgaC11B.1.36.80.001
ORF1ab/nsp1064D64DgaTgaC11B.1.3750.00082
ORF1ab/nsp1064D64DgaTgaC11B.1.3960.000706
ORF1ab/nsp1064D64GgAtgGt11B.1.4260.001009
ORF1ab/nsp1064D64GgAtgGt11B.1.4290.000024
ORF1ab/nsp1064D64EgaTgaG11B.1.4290.000024
ORF1ab/nsp1064D64DgaTgaC11B.1.4460.02
ORF1ab/nsp1064D64EgaTgaG11B.1.466.20.000391
ORF1ab/nsp1064D64DgaTgaC11B.1.5090.000866
ORF1ab/nsp1064D64GgAtgGt11B.1.5260.000024
ORF1ab/nsp1064D64NGatAat11B.1.5260.000024
ORF1ab/nsp1064D64DgaTgaC11B.1.5270.003704
ORF1ab/nsp1064D64DgaTgaC11B.1.5300.007143
ORF1ab/nsp1064D64DgaTgaC11B.1.5800.004065
ORF1ab/nsp1064D64YGatTat11B.1.5960.000087
ORF1ab/nsp1064D64DgaTgaC11B.1.6060.006024
ORF1ab/nsp1064D64YGatTat11B.1.617.10.000129
ORF1ab/nsp1064D64EgaTgaG11B.1.617.20.000004
ORF1ab/nsp1064D64DgaTgaC11B.1.6230.000536
ORF1ab/nsp1064D64DgaTgaC11B.1.6370.000073
ORF1ab/nsp1064D64EgaTgaG11B.1.830.015385
ORF1ab/nsp1064D64delGAT---11P.10.000016
ORF1ab/nsp1064D64EgaTgaG11P.1.10.000318
ORF1ab/nsp1064D64DgaTgaC11P.1.120.000484
ORF1ab/nsp1064D64DgaTgaC11P.1.170.000162
ORF1ab/nsp1064D64DgaTgaC11P.1.70.000319
ORF1ab/nsp1064D64delGAT---11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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