CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = Y136N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1136Y136NY136NnonsynTacAac5125110.998047671-673
ORF1ab/nsp1136Y136NY136NnonsynTaCAaT51210.00195312671-673

Details of the mutation Y136N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1136Y136NTacAac511512All0.000098
ORF1ab/nsp1136Y136NTaCAaT1512All0
ORF1ab/nsp1136Y136NTacAac155155AY.120.048989
ORF1ab/nsp1136Y136NTacAac3636AY.430.000159
ORF1ab/nsp1136Y136NTacAac3333AY.40.000051
ORF1ab/nsp1136Y136NTacAac3131B.1.1.70.000028
ORF1ab/nsp1136Y136NTacAac2828B.1.617.20.000105
ORF1ab/nsp1136Y136NTacAac2626AY.250.000156
ORF1ab/nsp1136Y136NTacAac2525B.10.000229
ORF1ab/nsp1136Y136NTacAac1919AY.470.000591
ORF1ab/nsp1136Y136NTacAac1717AY.440.000103
ORF1ab/nsp1136Y136NTacAac1313AY.30.000129
ORF1ab/nsp1136Y136NTacAac88AY.610.000838
ORF1ab/nsp1136Y136NTacAac66B.1.10.000109
ORF1ab/nsp1136Y136NTacAac55AY.1030.000031
ORF1ab/nsp1136Y136NTacAac55AY.390.000124
ORF1ab/nsp1136Y136NTacAac55AY.46.40.000823
ORF1ab/nsp1136Y136NTacAac55AY.750.00028
ORF1ab/nsp1136Y136NTacAac55B.1.1.370.000964
ORF1ab/nsp1136Y136NTacAac44B.1.6230.002146
ORF1ab/nsp1136Y136NTacAac44P.1.140.000191
ORF1ab/nsp1136Y136NTacAac33AY.270.000194
ORF1ab/nsp1136Y136NTacAac33AY.290.000047
ORF1ab/nsp1136Y136NTacAac33B.1.1770.00004
ORF1ab/nsp1136Y136NTacAac33B.1.20.000026
ORF1ab/nsp1136Y136NTacAac33B.1.6210.000266
ORF1ab/nsp1136Y136NTacAac22A.10.000564
ORF1ab/nsp1136Y136NTacAac22AY.1200.000074
ORF1ab/nsp1136Y136NTacAac22AY.140.000176
ORF1ab/nsp1136Y136NTacAac22AY.260.000057
ORF1ab/nsp1136Y136NTacAac22AY.3.10.000171
ORF1ab/nsp1136Y136NTacAac22AY.4.20.000043
ORF1ab/nsp1136Y136NTacAac22AY.510.001818
ORF1ab/nsp1136Y136NTacAac22AY.540.000191
ORF1ab/nsp1136Y136NTacAac22AY.99.20.000184
ORF1ab/nsp1136Y136NTacAac22B0.000256
ORF1ab/nsp1136Y136NTacAac22B.1.1.4090.005666
ORF1ab/nsp1136Y136NTacAac22B.1.1.5190.000079
ORF1ab/nsp1136Y136NTacAac22B.1.177.320.002699
ORF1ab/nsp1136Y136NTaCAaT12B.1.2580.000067
ORF1ab/nsp1136Y136NTacAac12B.1.2580.000067
ORF1ab/nsp1136Y136NTacAac22B.1.4290.000047
ORF1ab/nsp1136Y136NTacAac22B.6.60.001778
ORF1ab/nsp1136Y136NTacAac11AU.20.002421
ORF1ab/nsp1136Y136NTacAac11AY.1000.000046
ORF1ab/nsp1136Y136NTacAac11AY.1020.000027
ORF1ab/nsp1136Y136NTacAac11AY.1100.000113
ORF1ab/nsp1136Y136NTacAac11AY.1180.000063
ORF1ab/nsp1136Y136NTacAac11AY.1190.000035
ORF1ab/nsp1136Y136NTacAac11AY.130.000161
ORF1ab/nsp1136Y136NTacAac11AY.160.00038
ORF1ab/nsp1136Y136NTacAac11AY.46.50.000198
ORF1ab/nsp1136Y136NTacAac11AY.46.60.000072
ORF1ab/nsp1136Y136NTacAac11AY.60.000041
ORF1ab/nsp1136Y136NTacAac11AY.690.000187
ORF1ab/nsp1136Y136NTacAac11AY.7.10.000113
ORF1ab/nsp1136Y136NTacAac11AY.98.10.000048
ORF1ab/nsp1136Y136NTacAac11B.1.1.1710.003676
ORF1ab/nsp1136Y136NTacAac11B.1.1.1760.000439
ORF1ab/nsp1136Y136NTacAac11B.1.1.2280.003049
ORF1ab/nsp1136Y136NTacAac11B.1.1.3110.000358
ORF1ab/nsp1136Y136NTacAac11B.1.1.3180.000302
ORF1ab/nsp1136Y136NTacAac11B.1.1.4300.041667
ORF1ab/nsp1136Y136NTacAac11B.1.1.770.041667
ORF1ab/nsp1136Y136NTacAac11B.1.1600.000031
ORF1ab/nsp1136Y136NTacAac11B.1.160.300.002976
ORF1ab/nsp1136Y136NTacAac11B.1.1660.008475
ORF1ab/nsp1136Y136NTacAac11B.1.177.40.000211
ORF1ab/nsp1136Y136NTacAac11B.1.2790.000514
ORF1ab/nsp1136Y136NTacAac11B.1.2890.00266
ORF1ab/nsp1136Y136NTacAac11B.1.3510.00003
ORF1ab/nsp1136Y136NTacAac11B.1.351.30.000876
ORF1ab/nsp1136Y136NTacAac11B.1.3610.001289
ORF1ab/nsp1136Y136NTacAac11B.1.3800.006623
ORF1ab/nsp1136Y136NTacAac11B.1.5260.000024
ORF1ab/nsp1136Y136NTacAac11B.1.5380.008065
ORF1ab/nsp1136Y136NTacAac11B.4.70.010101
ORF1ab/nsp1136Y136NTacAac11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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