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CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = Y136H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1136Y136HY136HnonsynTacCac1161161671-673

Details of the mutation Y136H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1136Y136HTacCac116116All0.000022
ORF1ab/nsp1136Y136HTacCac1919AY.470.000591
ORF1ab/nsp1136Y136HTacCac1717B.1.1.70.000015
ORF1ab/nsp1136Y136HTacCac1212AY.40.000019
ORF1ab/nsp1136Y136HTacCac99AY.440.000055
ORF1ab/nsp1136Y136HTacCac99B.1.177.770.006536
ORF1ab/nsp1136Y136HTacCac66B.1.617.20.000023
ORF1ab/nsp1136Y136HTacCac44AY.430.000018
ORF1ab/nsp1136Y136HTacCac33AY.250.000018
ORF1ab/nsp1136Y136HTacCac33B.1.4290.000071
ORF1ab/nsp1136Y136HTacCac33B.1.6210.000266
ORF1ab/nsp1136Y136HTacCac22AY.370.000632
ORF1ab/nsp1136Y136HTacCac22AY.4.20.000043
ORF1ab/nsp1136Y136HTacCac22B.10.000018
ORF1ab/nsp1136Y136HTacCac22B.1.177.860.000367
ORF1ab/nsp1136Y136HTacCac22B.1.20.000018
ORF1ab/nsp1136Y136HTacCac22D.20.00015
ORF1ab/nsp1136Y136HTacCac22P.10.000032
ORF1ab/nsp1136Y136HTacCac11AY.1020.000027
ORF1ab/nsp1136Y136HTacCac11AY.290.000016
ORF1ab/nsp1136Y136HTacCac11AY.30.00001
ORF1ab/nsp1136Y136HTacCac11AY.610.000105
ORF1ab/nsp1136Y136HTacCac11AY.750.000056
ORF1ab/nsp1136Y136HTacCac11AY.9.10.000084
ORF1ab/nsp1136Y136HTacCac11AY.9.20.000037
ORF1ab/nsp1136Y136HTacCac11B.1.1.2840.000107
ORF1ab/nsp1136Y136HTacCac11B.1.1.5190.00004
ORF1ab/nsp1136Y136HTacCac11B.1.1600.000031
ORF1ab/nsp1136Y136HTacCac11B.1.1640.014925
ORF1ab/nsp1136Y136HTacCac11B.1.177.810.000189
ORF1ab/nsp1136Y136HTacCac11B.1.2060.000816
ORF1ab/nsp1136Y136HTacCac11B.1.4780.011765
ORF1ab/nsp1136Y136HTacCac11B.1.5610.000397
ORF1ab/nsp1136Y136HTacCac11B.1.575.10.002439
ORF1ab/nsp1136Y136HTacCac11B.1.5820.000491

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.