CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = T170I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1170T170IT170InonsynaCcaTc137413741773-775

Details of the mutation T170I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1170T170IaCcaTc13741374All0.000263
ORF1ab/nsp1170T170IaCcaTc387387B.1.1.70.000346
ORF1ab/nsp1170T170IaCcaTc179179B.1.1.5190.007108
ORF1ab/nsp1170T170IaCcaTc7979B.1.20.000696
ORF1ab/nsp1170T170IaCcaTc7575B.1.3510.002229
ORF1ab/nsp1170T170IaCcaTc6565AY.440.000396
ORF1ab/nsp1170T170IaCcaTc6464AY.40.0001
ORF1ab/nsp1170T170IaCcaTc5252B.1.4290.001224
ORF1ab/nsp1170T170IaCcaTc4545N.90.267857
ORF1ab/nsp1170T170IaCcaTc3737B.1.1.1410.074447
ORF1ab/nsp1170T170IaCcaTc3333B.1.1.830.089431
ORF1ab/nsp1170T170IaCcaTc3232B.1.617.20.00012
ORF1ab/nsp1170T170IaCcaTc2828B.1.10.000508
ORF1ab/nsp1170T170IaCcaTc2424B.1.3500.070381
ORF1ab/nsp1170T170IaCcaTc1919B.1.1.1700.023691
ORF1ab/nsp1170T170IaCcaTc1616B.1.360.002334
ORF1ab/nsp1170T170IaCcaTc1515B.10.000137
ORF1ab/nsp1170T170IaCcaTc1414B.1.2210.000994
ORF1ab/nsp1170T170IaCcaTc1313C.160.013786
ORF1ab/nsp1170T170IaCcaTc99B.1.258.170.000936
ORF1ab/nsp1170T170IaCcaTc88AY.1030.00005
ORF1ab/nsp1170T170IaCcaTc88AY.430.000035
ORF1ab/nsp1170T170IaCcaTc77AY.540.000667
ORF1ab/nsp1170T170IaCcaTc66B.1.1.280.001867
ORF1ab/nsp1170T170IaCcaTc66B.1.6320.040268
ORF1ab/nsp1170T170IaCcaTc66P.10.000095
ORF1ab/nsp1170T170IaCcaTc55B.1.1.250.002843
ORF1ab/nsp1170T170IaCcaTc55B.1.1.3540.02193
ORF1ab/nsp1170T170IaCcaTc55B.1.177.810.000947
ORF1ab/nsp1170T170IaCcaTc55B.1.4380.03268
ORF1ab/nsp1170T170IaCcaTc55B.1.4990.005252
ORF1ab/nsp1170T170IaCcaTc44AY.250.000024
ORF1ab/nsp1170T170IaCcaTc44AY.260.000113
ORF1ab/nsp1170T170IaCcaTc44AY.270.000259
ORF1ab/nsp1170T170IaCcaTc44AY.39.10.000158
ORF1ab/nsp1170T170IaCcaTc44B.1.1.2140.000222
ORF1ab/nsp1170T170IaCcaTc44B.1.1770.000053
ORF1ab/nsp1170T170IaCcaTc44B.1.2580.000266
ORF1ab/nsp1170T170IaCcaTc33AD.20.000657
ORF1ab/nsp1170T170IaCcaTc33AY.290.000047
ORF1ab/nsp1170T170IaCcaTc33AY.60.000123
ORF1ab/nsp1170T170IaCcaTc33AY.75.10.000541
ORF1ab/nsp1170T170IaCcaTc33B.1.1.1610.010601
ORF1ab/nsp1170T170IaCcaTc33B.1.2430.000209
ORF1ab/nsp1170T170IaCcaTc33B.1.3060.017143
ORF1ab/nsp1170T170IaCcaTc33B.1.4040.003906
ORF1ab/nsp1170T170IaCcaTc33B.1.5170.001281
ORF1ab/nsp1170T170IaCcaTc33B.1.6250.007059
ORF1ab/nsp1170T170IaCcaTc33P.1.140.000143
ORF1ab/nsp1170T170IaCcaTc22AY.1020.000053
ORF1ab/nsp1170T170IaCcaTc22AY.200.000078
ORF1ab/nsp1170T170IaCcaTc22AY.30.00002
ORF1ab/nsp1170T170IaCcaTc22AY.340.000194
ORF1ab/nsp1170T170IaCcaTc22AY.390.000049
ORF1ab/nsp1170T170IaCcaTc22AY.4.20.000043
ORF1ab/nsp1170T170IaCcaTc22AY.46.60.000144
ORF1ab/nsp1170T170IaCcaTc22B.1.1.2160.001781
ORF1ab/nsp1170T170IaCcaTc22B.1.1.2940.002532
ORF1ab/nsp1170T170IaCcaTc22B.1.1080.011628
ORF1ab/nsp1170T170IaCcaTc22B.1.1260.002551
ORF1ab/nsp1170T170IaCcaTc22B.1.177.860.000367
ORF1ab/nsp1170T170IaCcaTc22B.1.4270.000101
ORF1ab/nsp1170T170IaCcaTc22D.20.00015
ORF1ab/nsp1170T170IaCcaTc11A.190.009434
ORF1ab/nsp1170T170IaCcaTc11AY.1160.000287
ORF1ab/nsp1170T170IaCcaTc11AY.120.2.10.000498
ORF1ab/nsp1170T170IaCcaTc11AY.160.00038
ORF1ab/nsp1170T170IaCcaTc11AY.16.10.00047
ORF1ab/nsp1170T170IaCcaTc11AY.230.00007
ORF1ab/nsp1170T170IaCcaTc11AY.520.000814
ORF1ab/nsp1170T170IaCcaTc11AY.590.00053
ORF1ab/nsp1170T170IaCcaTc11AY.650.000533
ORF1ab/nsp1170T170IaCcaTc11AY.820.001357
ORF1ab/nsp1170T170IaCcaTc11AY.99.20.000092
ORF1ab/nsp1170T170IaCcaTc11B.1.1.1710.003676
ORF1ab/nsp1170T170IaCcaTc11B.1.1.2280.003049
ORF1ab/nsp1170T170IaCcaTc11B.1.1.3070.002532
ORF1ab/nsp1170T170IaCcaTc11B.1.1.3170.000412
ORF1ab/nsp1170T170IaCcaTc11B.1.1.330.000421
ORF1ab/nsp1170T170IaCcaTc11B.1.1.980.018519
ORF1ab/nsp1170T170IaCcaTc11B.1.177.170.000821
ORF1ab/nsp1170T170IaCcaTc11B.1.177.210.000076
ORF1ab/nsp1170T170IaCcaTc11B.1.177.40.000211
ORF1ab/nsp1170T170IaCcaTc11B.1.2340.000132
ORF1ab/nsp1170T170IaCcaTc11B.1.36.370.002778
ORF1ab/nsp1170T170IaCcaTc11B.1.3960.000706
ORF1ab/nsp1170T170IaCcaTc11B.1.4030.003268
ORF1ab/nsp1170T170IaCcaTc11B.1.466.20.000391
ORF1ab/nsp1170T170IaCcaTc11B.1.5870.001898
ORF1ab/nsp1170T170IaCcaTc11B.1.5940.03125
ORF1ab/nsp1170T170IaCcaTc11B.1.5960.000087
ORF1ab/nsp1170T170IaCcaTc11B.1.6210.000089
ORF1ab/nsp1170T170IaCcaTc11B.580.010204
ORF1ab/nsp1170T170IaCcaTc11C.110.010638
ORF1ab/nsp1170T170IaCcaTc11N.10.016949
ORF1ab/nsp1170T170IaCcaTc11N.30.005814

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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