CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = R73R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp173R73RR73RsyncgTcgC5564890.879496482-484
ORF1ab/nsp173R73RR73RsyncgTcgA556410.073741482-484
ORF1ab/nsp173R73RR73RsyncgTcgG556260.0467626482-484

Details of the mutation R73R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp173R73RcgTcgC489556All0.000094
ORF1ab/nsp173R73RcgTcgA41556All0.000008
ORF1ab/nsp173R73RcgTcgG26556All0.000005
ORF1ab/nsp173R73RcgTcgC113113AY.4.20.002451
ORF1ab/nsp173R73RcgTcgC4852B.10.00044
ORF1ab/nsp173R73RcgTcgG352B.10.000027
ORF1ab/nsp173R73RcgTcgA152B.10.000009
ORF1ab/nsp173R73RcgTcgC4447AY.40.000068
ORF1ab/nsp173R73RcgTcgG347AY.40.000005
ORF1ab/nsp173R73RcgTcgC2929AY.230.002023
ORF1ab/nsp173R73RcgTcgC2128B.1.1.70.000019
ORF1ab/nsp173R73RcgTcgA428B.1.1.70.000004
ORF1ab/nsp173R73RcgTcgG328B.1.1.70.000003
ORF1ab/nsp173R73RcgTcgC2425B.1.20.000211
ORF1ab/nsp173R73RcgTcgG125B.1.20.000009
ORF1ab/nsp173R73RcgTcgC2424B.1.1.1290.220183
ORF1ab/nsp173R73RcgTcgC2424B.1.1.3850.107143
ORF1ab/nsp173R73RcgTcgA1424B.1.617.20.000053
ORF1ab/nsp173R73RcgTcgC924B.1.617.20.000034
ORF1ab/nsp173R73RcgTcgG124B.1.617.20.000004
ORF1ab/nsp173R73RcgTcgC2121B.1.6370.001535
ORF1ab/nsp173R73RcgTcgC1418AY.1030.000087
ORF1ab/nsp173R73RcgTcgG418AY.1030.000025
ORF1ab/nsp173R73RcgTcgC1212AY.1180.000752
ORF1ab/nsp173R73RcgTcgC1111AY.440.000067
ORF1ab/nsp173R73RcgTcgA610AY.430.000027
ORF1ab/nsp173R73RcgTcgC410AY.430.000018
ORF1ab/nsp173R73RcgTcgA1010AY.610.001048
ORF1ab/nsp173R73RcgTcgC89AY.390.000198
ORF1ab/nsp173R73RcgTcgA19AY.390.000025
ORF1ab/nsp173R73RcgTcgC67AY.30.00006
ORF1ab/nsp173R73RcgTcgG17AY.30.00001
ORF1ab/nsp173R73RcgTcgC77B.1.350.11
ORF1ab/nsp173R73RcgTcgC46B.1.10.000073
ORF1ab/nsp173R73RcgTcgG26B.1.10.000036
ORF1ab/nsp173R73RcgTcgC66C.370.000696
ORF1ab/nsp173R73RcgTcgC55AY.290.000079
ORF1ab/nsp173R73RcgTcgC55AY.450.000608
ORF1ab/nsp173R73RcgTcgC44B.1.360.000584
ORF1ab/nsp173R73RcgTcgG34B.1.5260.000071
ORF1ab/nsp173R73RcgTcgC14B.1.5260.000024
ORF1ab/nsp173R73RcgTcgC33AY.1000.000138
ORF1ab/nsp173R73RcgTcgC33AY.330.0002
ORF1ab/nsp173R73RcgTcgC33AY.400.002893
ORF1ab/nsp173R73RcgTcgA33AY.75.10.000541
ORF1ab/nsp173R73RcgTcgC33B.1.1.2140.000166
ORF1ab/nsp173R73RcgTcgC22AY.1020.000053
ORF1ab/nsp173R73RcgTcgC22AY.340.000194
ORF1ab/nsp173R73RcgTcgC22B.1.1.5190.000079
ORF1ab/nsp173R73RcgTcgC22B.1.4290.000047
ORF1ab/nsp173R73RcgTcgC22B.1.4970.00063
ORF1ab/nsp173R73RcgTcgC22B.1.617.10.000258
ORF1ab/nsp173R73RcgTcgC22P.10.000032
ORF1ab/nsp173R73RcgTcgG11AY.1110.000183
ORF1ab/nsp173R73RcgTcgC11AY.1170.000085
ORF1ab/nsp173R73RcgTcgC11AY.1200.000037
ORF1ab/nsp173R73RcgTcgA11AY.16.10.00047
ORF1ab/nsp173R73RcgTcgC11AY.250.000006
ORF1ab/nsp173R73RcgTcgC11AY.420.00004
ORF1ab/nsp173R73RcgTcgC11AY.460.000104
ORF1ab/nsp173R73RcgTcgG11AY.46.60.000072
ORF1ab/nsp173R73RcgTcgA11AY.710.000475
ORF1ab/nsp173R73RcgTcgC11AY.750.000056
ORF1ab/nsp173R73RcgTcgC11AY.9.10.000084
ORF1ab/nsp173R73RcgTcgC11B.1.1.10.000327
ORF1ab/nsp173R73RcgTcgC11B.1.1.700.000341
ORF1ab/nsp173R73RcgTcgG11B.1.1600.000031
ORF1ab/nsp173R73RcgTcgC11B.1.177.700.005917
ORF1ab/nsp173R73RcgTcgC11B.1.177.810.000189
ORF1ab/nsp173R73RcgTcgC11B.1.2210.000071
ORF1ab/nsp173R73RcgTcgC11B.1.2400.000216
ORF1ab/nsp173R73RcgTcgC11B.1.2580.000067
ORF1ab/nsp173R73RcgTcgC11B.1.3510.00003
ORF1ab/nsp173R73RcgTcgC11B.1.4430.004673
ORF1ab/nsp173R73RcgTcgC11B.1.4690.00361
ORF1ab/nsp173R73RcgTcgG11B.1.5580.004566
ORF1ab/nsp173R73RcgTcgC11B.1.5960.000087
ORF1ab/nsp173R73RcgTcgC11B.1.6210.000089
ORF1ab/nsp173R73RcgTcgG11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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