CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = R73C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp173R73CR73CnonsynCgtTgt6456440.99845482-484
ORF1ab/nsp173R73CR73CnonsynCgTTgC64510.00155039482-484

Details of the mutation R73C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp173R73CCgtTgt644645All0.000123
ORF1ab/nsp173R73CCgTTgC1645All0
ORF1ab/nsp173R73CCgtTgt126126B.1.1.70.000113
ORF1ab/nsp173R73CCgtTgt107107AY.40.000167
ORF1ab/nsp173R73CCgtTgt4242B.1.258.231
ORF1ab/nsp173R73CCgtTgt4040D.20.003002
ORF1ab/nsp173R73CCgtTgt3232B.1.1390.02346
ORF1ab/nsp173R73CCgtTgt2222B.1.617.20.000083
ORF1ab/nsp173R73CCgtTgt1616AY.440.000097
ORF1ab/nsp173R73CCgtTgt1515AY.1200.000558
ORF1ab/nsp173R73CCgtTgt1414AY.250.000084
ORF1ab/nsp173R73CCgtTgt1414B.1.2400.003018
ORF1ab/nsp173R73CCgtTgt1010B.1.4090.007812
ORF1ab/nsp173R73CCgtTgt99AY.1030.000056
ORF1ab/nsp173R73CCgtTgt99AY.430.00004
ORF1ab/nsp173R73CCgtTgt88P.1.150.001859
ORF1ab/nsp173R73CCgtTgt77AY.200.000272
ORF1ab/nsp173R73CCgtTgt66AY.1180.000376
ORF1ab/nsp173R73CCgtTgt56B.1.10.000091
ORF1ab/nsp173R73CCgTTgC16B.1.10.000018
ORF1ab/nsp173R73CCgtTgt66B.1.20.000053
ORF1ab/nsp173R73CCgtTgt55AY.130.000805
ORF1ab/nsp173R73CCgtTgt55AY.30.00005
ORF1ab/nsp173R73CCgtTgt55AY.4.20.000108
ORF1ab/nsp173R73CCgtTgt55AY.610.000524
ORF1ab/nsp173R73CCgtTgt55C.36.30.002836
ORF1ab/nsp173R73CCgtTgt55P.10.000079
ORF1ab/nsp173R73CCgtTgt44AY.260.000113
ORF1ab/nsp173R73CCgtTgt44AY.390.000099
ORF1ab/nsp173R73CCgtTgt44AY.50.000083
ORF1ab/nsp173R73CCgtTgt44B.10.000037
ORF1ab/nsp173R73CCgtTgt44B.1.2580.000266
ORF1ab/nsp173R73CCgtTgt33AY.1000.000138
ORF1ab/nsp173R73CCgtTgt33AY.230.000209
ORF1ab/nsp173R73CCgtTgt33AY.330.0002
ORF1ab/nsp173R73CCgtTgt33B.1.1770.00004
ORF1ab/nsp173R73CCgtTgt33B.1.3510.000089
ORF1ab/nsp173R73CCgtTgt33P.1.140.000143
ORF1ab/nsp173R73CCgtTgt22A0.000774
ORF1ab/nsp173R73CCgtTgt22AY.1090.001479
ORF1ab/nsp173R73CCgtTgt22AY.4.50.000215
ORF1ab/nsp173R73CCgtTgt22AY.510.001818
ORF1ab/nsp173R73CCgtTgt22AY.9.10.000167
ORF1ab/nsp173R73CCgtTgt22B.1.1.4340.000697
ORF1ab/nsp173R73CCgtTgt22B.1.177.470.025974
ORF1ab/nsp173R73CCgtTgt22B.1.3770.009132
ORF1ab/nsp173R73CCgtTgt22B.1.4270.000101
ORF1ab/nsp173R73CCgtTgt22B.1.4290.000047
ORF1ab/nsp173R73CCgtTgt22B.1.5250.000226
ORF1ab/nsp173R73CCgtTgt22B.1.5260.000047
ORF1ab/nsp173R73CCgtTgt22B.1.6210.000177
ORF1ab/nsp173R73CCgtTgt22C.180.005181
ORF1ab/nsp173R73CCgtTgt22C.370.000232
ORF1ab/nsp173R73CCgtTgt11A.2.50.000499
ORF1ab/nsp173R73CCgtTgt11AD.20.000219
ORF1ab/nsp173R73CCgtTgt11AY.1020.000027
ORF1ab/nsp173R73CCgtTgt11AY.1100.000113
ORF1ab/nsp173R73CCgtTgt11AY.1130.000142
ORF1ab/nsp173R73CCgtTgt11AY.1170.000085
ORF1ab/nsp173R73CCgtTgt11AY.1190.000035
ORF1ab/nsp173R73CCgtTgt11AY.240.000431
ORF1ab/nsp173R73CCgtTgt11AY.290.000016
ORF1ab/nsp173R73CCgtTgt11AY.300.000396
ORF1ab/nsp173R73CCgtTgt11AY.4.30.000842
ORF1ab/nsp173R73CCgtTgt11AY.410.000294
ORF1ab/nsp173R73CCgtTgt11AY.460.000104
ORF1ab/nsp173R73CCgtTgt11AY.46.40.000165
ORF1ab/nsp173R73CCgtTgt11AY.46.60.000072
ORF1ab/nsp173R73CCgtTgt11AY.470.000031
ORF1ab/nsp173R73CCgtTgt11AY.60.000041
ORF1ab/nsp173R73CCgtTgt11AY.600.000938
ORF1ab/nsp173R73CCgtTgt11AY.750.000056
ORF1ab/nsp173R73CCgtTgt11AY.75.10.00018
ORF1ab/nsp173R73CCgtTgt11AY.800.001129
ORF1ab/nsp173R73CCgtTgt11AY.90.000068
ORF1ab/nsp173R73CCgtTgt11AY.940.000443
ORF1ab/nsp173R73CCgtTgt11AY.98.10.000048
ORF1ab/nsp173R73CCgtTgt11AY.990.001049
ORF1ab/nsp173R73CCgtTgt11B0.000128
ORF1ab/nsp173R73CCgtTgt11B.1.1.10.000327
ORF1ab/nsp173R73CCgtTgt11B.1.1.1760.000439
ORF1ab/nsp173R73CCgtTgt11B.1.1.2160.00089
ORF1ab/nsp173R73CCgtTgt11B.1.1.250.000569
ORF1ab/nsp173R73CCgtTgt11B.1.1.280.000311
ORF1ab/nsp173R73CCgtTgt11B.1.1.3060.000438
ORF1ab/nsp173R73CCgtTgt11B.1.1.3430.020833
ORF1ab/nsp173R73CCgtTgt11B.1.1.3970.002252
ORF1ab/nsp173R73CCgtTgt11B.1.1.4200.001006
ORF1ab/nsp173R73CCgtTgt11B.1.1.610.008772
ORF1ab/nsp173R73CCgtTgt11B.1.160.220.006757
ORF1ab/nsp173R73CCgtTgt11B.1.177.210.000076
ORF1ab/nsp173R73CCgtTgt11B.1.1890.004292
ORF1ab/nsp173R73CCgtTgt11B.1.2210.000071
ORF1ab/nsp173R73CCgtTgt11B.1.2340.000132
ORF1ab/nsp173R73CCgtTgt11B.1.2430.00007
ORF1ab/nsp173R73CCgtTgt11B.1.258.170.000104
ORF1ab/nsp173R73CCgtTgt11B.1.258.30.001675
ORF1ab/nsp173R73CCgtTgt11B.1.258.70.001912
ORF1ab/nsp173R73CCgtTgt11B.1.3690.000285
ORF1ab/nsp173R73CCgtTgt11B.1.3810.007812
ORF1ab/nsp173R73CCgtTgt11B.1.3960.000706
ORF1ab/nsp173R73CCgtTgt11B.1.438.10.000107
ORF1ab/nsp173R73CCgtTgt11B.1.5300.007143
ORF1ab/nsp173R73CCgtTgt11B.1.5600.00463
ORF1ab/nsp173R73CCgtTgt11B.1.5750.000303
ORF1ab/nsp173R73CCgtTgt11B.1.6050.005952
ORF1ab/nsp173R73CCgtTgt11B.350.007812
ORF1ab/nsp173R73CCgtTgt11B.400.000364
ORF1ab/nsp173R73CCgtTgt11C.36.3.10.002717
ORF1ab/nsp173R73CCgtTgt11P.1.60.001946
ORF1ab/nsp173R73CCgtTgt11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.