CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = R175C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1175R175CR175CnonsynCgtTgt105810540.996219788-790
ORF1ab/nsp1175R175CR175CnonsynCgTTgC105840.00378072788-790

Details of the mutation R175C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1175R175CCgtTgt10541058All0.000202
ORF1ab/nsp1175R175CCgTTgC41058All0.000001
ORF1ab/nsp1175R175CCgtTgt357357AY.40.000556
ORF1ab/nsp1175R175CCgtTgt117117B.1.1.70.000105
ORF1ab/nsp1175R175CCgtTgt6060B.1.617.20.000226
ORF1ab/nsp1175R175CCgtTgt5252AY.430.00023
ORF1ab/nsp1175R175CCgtTgt4343AY.440.000262
ORF1ab/nsp1175R175CCgtTgt2425AY.1030.000149
ORF1ab/nsp1175R175CCgTTgC125AY.1030.000006
ORF1ab/nsp1175R175CCgtTgt1821AY.1020.000477
ORF1ab/nsp1175R175CCgTTgC321AY.1020.00008
ORF1ab/nsp1175R175CCgtTgt2020AY.250.00012
ORF1ab/nsp1175R175CCgtTgt1818AY.4.20.00039
ORF1ab/nsp1175R175CCgtTgt1717AY.330.001135
ORF1ab/nsp1175R175CCgtTgt1717AY.98.10.000823
ORF1ab/nsp1175R175CCgtTgt1717B.1.20.00015
ORF1ab/nsp1175R175CCgtTgt1515AY.420.000603
ORF1ab/nsp1175R175CCgtTgt1313AY.1190.000459
ORF1ab/nsp1175R175CCgtTgt1010AY.30.000099
ORF1ab/nsp1175R175CCgtTgt99AY.1140.00208
ORF1ab/nsp1175R175CCgtTgt99AY.230.000628
ORF1ab/nsp1175R175CCgtTgt99AY.50.000186
ORF1ab/nsp1175R175CCgtTgt88AY.370.002528
ORF1ab/nsp1175R175CCgtTgt88AY.7.10.000902
ORF1ab/nsp1175R175CCgtTgt88B.10.000073
ORF1ab/nsp1175R175CCgtTgt77AY.1050.004502
ORF1ab/nsp1175R175CCgtTgt77AY.1060.002344
ORF1ab/nsp1175R175CCgtTgt77B.1.3510.000208
ORF1ab/nsp1175R175CCgtTgt66AY.190.006842
ORF1ab/nsp1175R175CCgtTgt66AY.200.000233
ORF1ab/nsp1175R175CCgtTgt66AY.260.00017
ORF1ab/nsp1175R175CCgtTgt66AY.290.000095
ORF1ab/nsp1175R175CCgtTgt66AY.39.10.000238
ORF1ab/nsp1175R175CCgtTgt66P.10.000095
ORF1ab/nsp1175R175CCgtTgt55AY.140.00044
ORF1ab/nsp1175R175CCgtTgt55AY.9.10.000419
ORF1ab/nsp1175R175CCgtTgt55B.1.258.160.008183
ORF1ab/nsp1175R175CCgtTgt55B.1.4290.000118
ORF1ab/nsp1175R175CCgtTgt44AY.1000.000184
ORF1ab/nsp1175R175CCgtTgt44AY.1200.000149
ORF1ab/nsp1175R175CCgtTgt44AY.70.000784
ORF1ab/nsp1175R175CCgtTgt44B.1.177.40.000844
ORF1ab/nsp1175R175CCgtTgt44B.1.5960.000349
ORF1ab/nsp1175R175CCgtTgt33AY.460.000312
ORF1ab/nsp1175R175CCgtTgt33AY.46.60.000217
ORF1ab/nsp1175R175CCgtTgt33AY.470.000093
ORF1ab/nsp1175R175CCgtTgt33AY.690.00056
ORF1ab/nsp1175R175CCgtTgt33AY.9.20.00011
ORF1ab/nsp1175R175CCgtTgt33B.1.1.5190.000119
ORF1ab/nsp1175R175CCgtTgt33B.1.1.700.001023
ORF1ab/nsp1175R175CCgtTgt22AY.10.000791
ORF1ab/nsp1175R175CCgtTgt22AY.1110.000366
ORF1ab/nsp1175R175CCgtTgt22AY.120.000632
ORF1ab/nsp1175R175CCgtTgt22AY.3.10.000171
ORF1ab/nsp1175R175CCgtTgt22AY.350.000466
ORF1ab/nsp1175R175CCgtTgt22AY.4.50.000215
ORF1ab/nsp1175R175CCgtTgt22AY.520.001629
ORF1ab/nsp1175R175CCgtTgt22AY.60.000082
ORF1ab/nsp1175R175CCgtTgt22AY.90.000135
ORF1ab/nsp1175R175CCgtTgt22AY.920.000575
ORF1ab/nsp1175R175CCgtTgt22AY.980.000158
ORF1ab/nsp1175R175CCgtTgt22B.1.1770.000026
ORF1ab/nsp1175R175CCgtTgt22B.1.2340.000264
ORF1ab/nsp1175R175CCgtTgt22B.1.4970.00063
ORF1ab/nsp1175R175CCgtTgt22B.1.5260.000047
ORF1ab/nsp1175R175CCgtTgt22B.1.5950.000522
ORF1ab/nsp1175R175CCgtTgt22C.380.016129
ORF1ab/nsp1175R175CCgtTgt110.055556
ORF1ab/nsp1175R175CCgtTgt11A.10.000282
ORF1ab/nsp1175R175CCgtTgt11AM.40.003571
ORF1ab/nsp1175R175CCgtTgt11AY.1010.00049
ORF1ab/nsp1175R175CCgtTgt11AY.1180.000063
ORF1ab/nsp1175R175CCgtTgt11AY.1210.000135
ORF1ab/nsp1175R175CCgtTgt11AY.130.000161
ORF1ab/nsp1175R175CCgtTgt11AY.170.008197
ORF1ab/nsp1175R175CCgtTgt11AY.23.10.000417
ORF1ab/nsp1175R175CCgtTgt11AY.340.000097
ORF1ab/nsp1175R175CCgtTgt11AY.34.10.00051
ORF1ab/nsp1175R175CCgtTgt11AY.390.000025
ORF1ab/nsp1175R175CCgtTgt11AY.400.000964
ORF1ab/nsp1175R175CCgtTgt11AY.450.000122
ORF1ab/nsp1175R175CCgtTgt11AY.46.30.000934
ORF1ab/nsp1175R175CCgtTgt11AY.540.000095
ORF1ab/nsp1175R175CCgtTgt11AY.700.000209
ORF1ab/nsp1175R175CCgtTgt11AY.75.10.00018
ORF1ab/nsp1175R175CCgtTgt11AY.760.004831
ORF1ab/nsp1175R175CCgtTgt11AY.800.001129
ORF1ab/nsp1175R175CCgtTgt11AY.870.000833
ORF1ab/nsp1175R175CCgtTgt11AY.930.000273
ORF1ab/nsp1175R175CCgtTgt11AY.940.000443
ORF1ab/nsp1175R175CCgtTgt11B.1.10.000018
ORF1ab/nsp1175R175CCgtTgt11B.1.1.1890.001513
ORF1ab/nsp1175R175CCgtTgt11B.1.1.2840.000107
ORF1ab/nsp1175R175CCgtTgt11B.1.1.3110.000358
ORF1ab/nsp1175R175CCgtTgt11B.1.1.3180.000302
ORF1ab/nsp1175R175CCgtTgt11B.1.1.3510.002793
ORF1ab/nsp1175R175CCgtTgt11B.1.1.630.000386
ORF1ab/nsp1175R175CCgtTgt11B.1.160.160.000929
ORF1ab/nsp1175R175CCgtTgt11B.1.177.210.000076
ORF1ab/nsp1175R175CCgtTgt11B.1.177.700.005917
ORF1ab/nsp1175R175CCgtTgt11B.1.2210.000071
ORF1ab/nsp1175R175CCgtTgt11B.1.2430.00007
ORF1ab/nsp1175R175CCgtTgt11B.1.258.170.000104
ORF1ab/nsp1175R175CCgtTgt11B.1.2930.0125
ORF1ab/nsp1175R175CCgtTgt11B.1.3560.001727
ORF1ab/nsp1175R175CCgtTgt11B.1.36.180.00042
ORF1ab/nsp1175R175CCgtTgt11B.1.3720.010989
ORF1ab/nsp1175R175CCgtTgt11B.1.4230.010204
ORF1ab/nsp1175R175CCgtTgt11B.1.4270.00005
ORF1ab/nsp1175R175CCgtTgt11B.1.5870.001898
ORF1ab/nsp1175R175CCgtTgt11B.1.6090.000479
ORF1ab/nsp1175R175CCgtTgt11B.1.6120.002653
ORF1ab/nsp1175R175CCgtTgt11B.1.619.10.000641
ORF1ab/nsp1175R175CCgtTgt11B.1.621.10.000506
ORF1ab/nsp1175R175CCgtTgt11B.1.6370.000073
ORF1ab/nsp1175R175CCgtTgt11B.580.010204
ORF1ab/nsp1175R175CCgtTgt11D.20.000075
ORF1ab/nsp1175R175CCgtTgt11P.1.170.000162
ORF1ab/nsp1175R175CCgtTgt11P.1.70.000319
ORF1ab/nsp1175R175CCgtTgt11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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