CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = L16R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp116L16RL16RnonsyncTccGc29280.965517311-313
ORF1ab/nsp116L16RL16RnonsyncTCcGT2910.0344828311-313

Details of the mutation L16R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp116L16RcTccGc2829All0.000005
ORF1ab/nsp116L16RcTCcGT129All0
ORF1ab/nsp116L16RcTccGc99P.1.140.00043
ORF1ab/nsp116L16RcTccGc77B.1.1.70.000006
ORF1ab/nsp116L16RcTccGc22AY.430.000009
ORF1ab/nsp116L16RcTccGc22B.1.1.330.000842
ORF1ab/nsp116L16RcTccGc11AY.30.00001
ORF1ab/nsp116L16RcTccGc11AY.350.000233
ORF1ab/nsp116L16RcTccGc11AY.390.000025
ORF1ab/nsp116L16RcTccGc11AY.40.000002
ORF1ab/nsp116L16RcTccGc11AY.460.000104
ORF1ab/nsp116L16RcTccGc11AY.46.20.000635
ORF1ab/nsp116L16RcTCcGT11B0.000128
ORF1ab/nsp116L16RcTccGc11B.1.1.3170.000412
ORF1ab/nsp116L16RcTccGc11B.1.360.000146

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.