CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp1 : Mut = L16F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp116L16FL16FnonsynCtcTtc9919810.989909311-313
ORF1ab/nsp116L16FL16FnonsynCtCTtT991100.0100908311-313

Details of the mutation L16F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp116L16FCtcTtc981991All0.000188
ORF1ab/nsp116L16FCtCTtT10991All0.000002
ORF1ab/nsp116L16FCtcTtc200200AY.1190.007062
ORF1ab/nsp116L16FCtcTtc182182B.1.1.70.000163
ORF1ab/nsp116L16FCtcTtc5959B.1.617.20.000222
ORF1ab/nsp116L16FCtcTtc4951AY.40.000076
ORF1ab/nsp116L16FCtCTtT251AY.40.000003
ORF1ab/nsp116L16FCtcTtc4343AY.750.002409
ORF1ab/nsp116L16FCtcTtc2828AY.4.20.000607
ORF1ab/nsp116L16FCtcTtc2727AY.250.000162
ORF1ab/nsp116L16FCtcTtc2323AY.430.000102
ORF1ab/nsp116L16FCtcTtc2323B.1.20.000203
ORF1ab/nsp116L16FCtcTtc2121P.10.000331
ORF1ab/nsp116L16FCtcTtc2020B.1.177.150.012618
ORF1ab/nsp116L16FCtcTtc1919AY.870.01582
ORF1ab/nsp116L16FCtcTtc1818AY.440.00011
ORF1ab/nsp116L16FCtcTtc1818P.1.10.005718
ORF1ab/nsp116L16FCtcTtc1313AY.260.000368
ORF1ab/nsp116L16FCtcTtc1111AY.1000.000506
ORF1ab/nsp116L16FCtcTtc1111B.10.000101
ORF1ab/nsp116L16FCtcTtc1111B.1.1770.000145
ORF1ab/nsp116L16FCtcTtc810B.1.10.000145
ORF1ab/nsp116L16FCtCTtT210B.1.10.000036
ORF1ab/nsp116L16FCtcTtc99AY.30.00009
ORF1ab/nsp116L16FCtcTtc99B.1.5260.000212
ORF1ab/nsp116L16FCtcTtc77AY.1130.000997
ORF1ab/nsp116L16FCtcTtc77AY.290.00011
ORF1ab/nsp116L16FCtcTtc66AY.1030.000037
ORF1ab/nsp116L16FCtcTtc66AY.390.000148
ORF1ab/nsp116L16FCtcTtc55AY.1210.000677
ORF1ab/nsp116L16FCtcTtc55AY.140.00044
ORF1ab/nsp116L16FCtcTtc55AY.50.000103
ORF1ab/nsp116L16FCtcTtc34AY.230.000209
ORF1ab/nsp116L16FCtCTtT14AY.230.00007
ORF1ab/nsp116L16FCtcTtc44AY.540.000381
ORF1ab/nsp116L16FCtcTtc44B.1.1.5190.000159
ORF1ab/nsp116L16FCtcTtc44B.1.177.570.001124
ORF1ab/nsp116L16FCtcTtc44B.1.2430.000278
ORF1ab/nsp116L16FCtcTtc44B.1.4270.000202
ORF1ab/nsp116L16FCtcTtc33AY.1020.00008
ORF1ab/nsp116L16FCtcTtc33AY.130.000483
ORF1ab/nsp116L16FCtcTtc33AY.16.10.00141
ORF1ab/nsp116L16FCtcTtc33AY.240.001293
ORF1ab/nsp116L16FCtcTtc33AY.470.000093
ORF1ab/nsp116L16FCtcTtc33AY.550.002752
ORF1ab/nsp116L16FCtcTtc33AY.9.10.000251
ORF1ab/nsp116L16FCtcTtc33AY.99.20.000276
ORF1ab/nsp116L16FCtcTtc33B.1.1.2220.000612
ORF1ab/nsp116L16FCtcTtc33B.1.4290.000071
ORF1ab/nsp116L16FCtcTtc33B.1.5960.000261
ORF1ab/nsp116L16FCtcTtc23B.1.617.10.000258
ORF1ab/nsp116L16FCtCTtT13B.1.617.10.000129
ORF1ab/nsp116L16FCtcTtc22AY.160.000759
ORF1ab/nsp116L16FCtcTtc22AY.23.10.000835
ORF1ab/nsp116L16FCtcTtc22AY.270.000129
ORF1ab/nsp116L16FCtcTtc22AY.450.000243
ORF1ab/nsp116L16FCtcTtc22AY.460.000208
ORF1ab/nsp116L16FCtcTtc22AY.60.000082
ORF1ab/nsp116L16FCtcTtc22AY.620.000871
ORF1ab/nsp116L16FCtCTtT22B.1.1.2140.000111
ORF1ab/nsp116L16FCtcTtc22B.1.1600.000062
ORF1ab/nsp116L16FCtcTtc22B.1.177.20.009091
ORF1ab/nsp116L16FCtcTtc22B.1.3510.000059
ORF1ab/nsp116L16FCtcTtc12B.1.36.180.00042
ORF1ab/nsp116L16FCtCTtT12B.1.36.180.00042
ORF1ab/nsp116L16FCtcTtc22B.1.6300.010471
ORF1ab/nsp116L16FCtcTtc22C.370.000232
ORF1ab/nsp116L16FCtcTtc22Q.80.00033
ORF1ab/nsp116L16FCtcTtc11AA.10.007246
ORF1ab/nsp116L16FCtcTtc11AY.100.00053
ORF1ab/nsp116L16FCtcTtc11AY.1100.000113
ORF1ab/nsp116L16FCtcTtc11AY.1170.000085
ORF1ab/nsp116L16FCtcTtc11AY.1180.000063
ORF1ab/nsp116L16FCtcTtc11AY.1200.000037
ORF1ab/nsp116L16FCtcTtc11AY.170.008197
ORF1ab/nsp116L16FCtcTtc11AY.200.000039
ORF1ab/nsp116L16FCtcTtc11AY.330.000067
ORF1ab/nsp116L16FCtcTtc11AY.350.000233
ORF1ab/nsp116L16FCtcTtc11AY.39.10.00004
ORF1ab/nsp116L16FCtcTtc11AY.420.00004
ORF1ab/nsp116L16FCtcTtc11AY.46.50.000198
ORF1ab/nsp116L16FCtcTtc11AY.570.000656
ORF1ab/nsp116L16FCtcTtc11AY.680.000274
ORF1ab/nsp116L16FCtcTtc11AY.70.000196
ORF1ab/nsp116L16FCtcTtc11AY.700.000209
ORF1ab/nsp116L16FCtcTtc11AY.740.000116
ORF1ab/nsp116L16FCtcTtc11AY.75.10.00018
ORF1ab/nsp116L16FCtcTtc11AY.80.000606
ORF1ab/nsp116L16FCtcTtc11AY.90.000068
ORF1ab/nsp116L16FCtcTtc11AY.9.20.000037
ORF1ab/nsp116L16FCtcTtc11AY.980.000079
ORF1ab/nsp116L16FCtcTtc11AY.98.10.000048
ORF1ab/nsp116L16FCtcTtc11B.1.1.2160.00089
ORF1ab/nsp116L16FCtCTtT11B.1.1.2840.000107
ORF1ab/nsp116L16FCtcTtc11B.1.1.2940.001266
ORF1ab/nsp116L16FCtcTtc11B.1.1.3690.000446
ORF1ab/nsp116L16FCtcTtc11B.1.1.3890.006061
ORF1ab/nsp116L16FCtcTtc11B.1.1.4340.000349
ORF1ab/nsp116L16FCtcTtc11B.1.1.630.000386
ORF1ab/nsp116L16FCtcTtc11B.1.177.40.000211
ORF1ab/nsp116L16FCtcTtc11B.1.177.650.000665
ORF1ab/nsp116L16FCtcTtc11B.1.2060.000816
ORF1ab/nsp116L16FCtcTtc11B.1.2100.002132
ORF1ab/nsp116L16FCtcTtc11B.1.2340.000132
ORF1ab/nsp116L16FCtcTtc11B.1.2410.000812
ORF1ab/nsp116L16FCtcTtc11B.1.2580.000067
ORF1ab/nsp116L16FCtcTtc11B.1.258.170.000104
ORF1ab/nsp116L16FCtcTtc11B.1.3130.006579
ORF1ab/nsp116L16FCtcTtc11B.1.3400.004292
ORF1ab/nsp116L16FCtcTtc11B.1.3460.001311
ORF1ab/nsp116L16FCtcTtc11B.1.4260.001009
ORF1ab/nsp116L16FCtcTtc11B.1.428.20.033333
ORF1ab/nsp116L16FCtcTtc11B.1.5010.007353
ORF1ab/nsp116L16FCtcTtc11B.1.6090.000479
ORF1ab/nsp116L16FCtcTtc11B.1.6120.002653
ORF1ab/nsp116L16FCtcTtc11B.1.6330.041667
ORF1ab/nsp116L16FCtcTtc11B.1.6370.000073
ORF1ab/nsp116L16FCtcTtc11C.1.20.004255
ORF1ab/nsp116L16FCtcTtc11C.260.007353
ORF1ab/nsp116L16FCtcTtc11P.1.100.000269
ORF1ab/nsp116L16FCtcTtc11P.1.140.000048
ORF1ab/nsp116L16FCtcTtc11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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